516 research outputs found

    Caça e pastorícia no calcolítico do NW de Portugal: o caso da estação arqueológica de Bitarados

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    Os autores publicam as primeiras evidências arqueozoológicas relacionadas com a pastorícia e com a caça detectadas no Calcolítico do Noroeste do País, recolhidas no sítio arqueológico de Bitarados (concelho de Esposende) as quais foram objecto de comparação com os resultados obtidos para outras áreas do Noroeste Peninsular.Hunting and pastoralism in the Calcolithic of the NW of Portugal: the case study of Bitarados - The authors publish the first bones of animals related to the pastoral and the hunting found in the Calcolithic of the Northwest of Portugal, collected in the archaeological site of Bitarados (municipality of Esposende) which have been compared with results for other areas of the Northwest of Iberia

    The vitality of pattern recognition and image analysis

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    Editorial sobre la selección de mejores artículos presentados en la conferencia internacional IbPRIA 2015 celebrada en Madeira, Portugal

    Challenges and Opportunities to Increase Carbon Sequestration in Subtropical Grazing Lands

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    Livestock production has a significant environmental footprint. However, adoption of regenerative grazing land management practices can serve as a means of producing food with lower, or even net positive environmental impacts. Globally, much of the grazing land ecosystems are degraded due to improper management. This is particularly true in the southeastern US, where extensive areas of planted pastures are degraded due to inadequate nutrient and soil management. In this presentation, we will discuss the opportunities and challenges associated with increasing soil and ecosystem C sequestration in subtropical grazing lands through regenerative management practices. Introductio

    Gene structure, transcripts and calciotropic effects of the PTH family of peptides in Xenopus and chicken

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    <p>Abstract</p> <p>Background</p> <p>Parathyroid hormone (PTH) and PTH-related peptide (PTHrP) belong to a family of endocrine factors that share a highly conserved N-terminal region (amino acids 1-34) and play key roles in calcium homeostasis, bone formation and skeletal development. Recently, PTH-like peptide (PTH-L) was identified in teleost fish raising questions about the evolution of these proteins. Although PTH and PTHrP have been intensively studied in mammals their function in other vertebrates is poorly documented. Amphibians and birds occupy unique phylogenetic positions, the former at the transition of aquatic to terrestrial life and the latter at the transition to homeothermy. Moreover, both organisms have characteristics indicative of a complex system in calcium regulation. This study investigated PTH family evolution in vertebrates with special emphasis on <it>Xenopus </it>and chicken.</p> <p>Results</p> <p>The PTH-L gene is present throughout the vertebrates with the exception of placental mammals. Gene structure of PTH and PTH-L seems to be conserved in vertebrates while PTHrP gene structure is divergent and has acquired new exons and alternative promoters. Splice variants of PTHrP and PTH-L are common in <it>Xenopus </it>and chicken and transcripts of the former have a widespread tissue distribution, although PTH-L is more restricted. PTH is widely expressed in fish tissue but from <it>Xenopus </it>to mammals becomes largely restricted to the parathyroid gland. The N-terminal (1-34) region of PTH, PTHrP and PTH-L in <it>Xenopus </it>and chicken share high sequence conservation and the capacity to modify calcium fluxes across epithelia suggesting a conserved role in calcium metabolism possibly via similar receptors.</p> <p>Conclusions</p> <p>The parathyroid hormone family contains 3 principal members, PTH, PTHrP and the recently identified PTH-L. In teleosts there are 5 genes which encode PTHrP (2), PTH (2) and PTH-L and in tetrapods there are 3 genes (PTHrP, PTH and PTH-L), the exception is placental mammals which have 2 genes and lack PTH-L. It is hypothesized that genes of the PTH family appeared at approximately the same time during the vertebrate radiation and evolved via gene duplication/deletion events. PTH-L was lost from the genome of eutherian mammals and PTH, which has a paracrine distribution in lower vertebrates, became the product of a specific endocrine tissue in Amphibia, the parathyroid gland. The PTHrP gene organisation diverged and became more complex in vertebrates and retained its widespread tissue distribution which is congruent with its paracrine nature.</p

    Medios sociales y riesgo de imagen

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    Clear-water scour at comparatively large cylindrical piers

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    New long-duration clear-water scour data were collected at single cylindrical piers with the objective of investigating the effect of sediment coarseness, Dp=D50 (Dp = pier diameter; D50 = median grain size) on the equilibrium scour depth and improving the scour depth time evolution modeling by making use of the exponential function suggested in the literature. Experiments were carried out for the flow intensity close to the threshold condition of initiation of sediment motion, imposing wide changes of sediment coarseness and flow shallowness, d=Dp (d = approach flow depth). The effect of sediment coarseness on the equilibrium scour depth was identified; existing predictors were modified to incorporate this effect for U=Uc ≈ 1.0; Dp=D50 > ≈60 and d=Dp ≥ 0.5; the complete characterization of a known scour depth time evolution model was achieved for U=Uc ≈ 1.0, 60 < Dp=D50 < 500 and 0.5 ≤ d=Dp ≤ 5.0

    Magnetoliposomes containing magnesium ferrite nanoparticles for enhanced therapeutic potential of curcumin

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    In this work, magnesium ferrite nanoparticles with superparamagnetic behavior and sizes around 20 nm were prepared and characterized. The structural and magnetic properties of these nanoparticles were evaluated by XRD, SEM and SQUID. In order to further develop applications in cancer therapy, the prepared MgFe2O4 nanoparticles were covered with a lipid bilayer (solid magnetoliposomes) or incorporated in lipid vesicles, forming aqueous magnetoliposomes.info:eu-repo/semantics/publishedVersio

    Actinomycosis Causing Recurrent Perianal Fistulae

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    Actinomycosis is a rare but easily curable infection that should be considered in the differential diagnosis of perianal fistulizing disease. We present the case of a 26-year-old woman with complex perianal fistulae, including trans-sphincteric and suprasphincteric fistulous tracts and a rectovaginal fistula, requiring multiple abscess drainages, seton placement, and antibiotic courses, with little improvement. After extensive investigation, Actinomyces spp. was identified in anal cytology. The patient underwent a 6-week course of intravenous penicillin followed by oral amoxicillin, with remarkable improvement. This case illustrates the importance of pursuing less common diagnoses in refractory complex perianal disease, such as actinomycosis.info:eu-repo/semantics/publishedVersio

    A estação arqueológica das Boucinhas, Regueira, Vitorino de Piães, Ponte de Lima (Norte de Portugal)

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    Publicam-se os resultados das sondagens arqueológicas realizadas no povoado da Idade do Bronze da Boucinha, em Vitorino de Piães, Ponte de Lima.Projeto FCT: The Entre-Douro-e-Minho landscape since middle of 3rd to the end of 2nd millenia BC.info:eu-repo/semantics/publishedVersio
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