333 research outputs found
Learn, Teach, Heal: Articulations of Indigeneity and Spirituality in Indigenous Tourism in British Columbia, Canada
âLearn, Teach, Healâ encapsulates what seems to be occurring in Indigenous Tourism on Vancouver Island and the Haida Gwaii in British Columbia, Canada. Operating as a âTourist-researcherâ in 2017 and 2018, I was there at a time when Indigenous Tourism was booming, partly facilitated by the political movement of Truth & Reconciliation. Tourism is often seen as a shallow, commercial and artificial activity, yet such a view risks speaking over the various reasons why hosts choose to engage in the industry. This dissertation offers a case study based on tours, performances and interviews with six people. The research foregrounds the voices and experiences of: Andy Everson, Tana Thomas, Roy Henry Vickers, Tsimka Martin, Kâodi Nelson and Alix Goetzinger. In listening to how they present their work, I study how indigeneity and spirituality were being articulated in ways that relate to processes of decolonisation. Whilst they were all engaged in tourism for their own different reasons, a common theme that emerged was the goal to use tourism to learn, teach and heal, both for themselves and for their guests. Learning how to be guides and performers, their languages, traditional practices, histories and politics, they were able to explore with tourists aspects of their indigeneity and spirituality, illustrate diversity of peoples and practices, and teach about their values and hopes for the future. Healing is gained through having a space to learn and to teach, and to restore pride to the communities by taking control of the narratives. It is my contention that Indigenous Tourism is offering these six people sites of âbecomingâ and âreclaimingâ in a way that puts decolonisation into practice
ORCID EPrints Implementation Survey Analysis
This report explores the results of a survey of users on their requirements and plans for integrating ORCID functionality into EPrints repository software. The community was invited to share their use cases, and an online survey based on this information was conducted to determine the priorities and needs of the wider community
Helen Matthews Lewis: Living Social Justice in Appalachia
Often referred to as the leader of inspiration in Appalachian studies, Helen Matthews Lewis linked scholarship with activism and encouraged deeper analysis of the region. Lewis shaped the field of Appalachian studies by emphasizing community participation and challenging traditional perceptions of the region and its people. Helen Matthews Lewis: Living Social Justice in Appalachia, a collection of Lewisâs writings and memories that document her life and work, begins in 1943 with her job on the yearbook staff at Georgia State College for Women with Mary Flannery OâConnor.
Editors Patricia D. Beaver and Judith Jennings highlight the achievements of Lewisâs extensive career, examining her role as a teacher and activist at Clinch Valley College (now University of Virginia at Wise) and East Tennessee State University in the 1960s, as well as her work with Appalshop and the Highland Center. Helen Matthews Lewis connects Lewisâs works to wider social movements by examining the history of progressive activism in Appalachia. The book provides unique insight into the development of regional studies and the life of a dynamic revolutionary, delivering a captivating and personal narrative of one womanâs mission of activism and social justice.
Helen Matthews Lewis has served as the director of the Berea College Appalachian Center, Appalshopâs Appalachian History Film Project, and the Highlander Research and Education Center. She is coauthor of Mountain Sisters: From Convent to Community in Appalachia and Colonialism in Modern America: The Appalachian Case.
Patricia D. Beaver, director of the Center for Appalachian Studies and professor of anthropology at Appalachian State University, is coeditor of Tales from Sacred Wind: Coming of Age in Appalachia.
Judith Jennings, executive director of the Kentucky Foundation for Women, is the author of Gender, Religion, and Radicalism in the Long Eighteenth Century: The âIngenious Quakerâ and Her Connections.
This book will be welcomed by those of us who found in Helen a role model who combines the life of the mind, the thirst for social justice, and the wisdom of soulful humor. For those others who are looking for such a role model have you made a discovery!ââRichard A. Couto, editor of Political and Civic Leadership: A Reference Handbook
This rich collection of memories, photographs, commentaries, and archival documents is an exemplary weave of history and biographyâthe lived story of Appalachian social movements over much of the twentieth century. The sweeping chronicle of Helen Lewisâs actions and words reveals how she continues to make history by living social justice and refusing to capitulate to unjust power. The lessons could not be more timely, instructive, and inspiring. --Barbara Ellen Smith, author of Neither Separate Nor Equal: Women, Race and Class in the South
It is one thing to speak truth to power. Helen does that with intelligence and wit -- to southern segregationists, coal companies, and academic institutions. Itâs another thing to speak truth with the powerless. On nearly every page of this wonderful book, Helen combines her commitment to those who lack power with trust in their agency. She breaks into the unruly and uncontainable, and wraps \u27the belt of truth around our waist.\u27 --Anne Lewis, director of Morristown: in the air and sun
In showcasing Helen Matthews Lewis, Beaver and Jennings remind us that an individual impassioned to do the right thing will make a positive difference. . . . the editors have also offered us Lewis\u27 legacy as a challenge to examine our own roles vis-a-vis committing to transform our communities. --Courier-Journal
Lewis has achieved the status of an icon among Appalachian activists and scholars. . . . An important book. --Appalachian Heritage
âBrings together in one volume Lewisâs many contributions to Appalachian Studies. . . . The book reveals the breadth and depth of scholarship and activism in Appalachia and will no doubt become a classic.â--West Virginia History
âProvides a more intimate insight into her life and her impact on people and society than a more formal portrait could. . . . Recommended.â--Choice
A fitting tribute to a woman who deserves greater acknowledgment and appreciation for her lifetime of work in Appalachia and for the betterment of struggling communities everywhere...The work is a success. -- Joseph Witt- -- Journal of Agricultural and Environmental Ethics
Winner of the Appalachian Writers Associationâs Book of the Year Award for Nonfictionhttps://uknowledge.uky.edu/upk_appalachian_studies/1028/thumbnail.jp
Dataset for ORCID EPrints Implementation
A survey canvassing user requirements for integration of EPrints software with the ORCID service was circulated to four mailing lists. Although the target audience was the UK EPrints user community, the survey was open to anyone, so included a number of international responses. This dataset includes an anonymised version of the download of results from Bristol Online Surveys and a copy of the survey form.A survey was circulated to four mailing lists - [email protected], [email protected], [email protected], [email protected]
Although the target audience was the UK EPrints user community, the survey was open to anyone, so included a number of international responses.
A copy of the survey form is included with the dataset.
Analysis was taken from the Bristol Online Surveys tool. No further processing was carried out.Data has been redacted as follows:
Institution names have been replaced with a country.
Job roles have been removed
Other data points in free text comments that would identify a respondent, an individual or an institution have been replaced with a generic term (e.g. [deleted name]).Columns have the full text of the question. Additionally, a copy of the original survey has been provided for information.
Some observations in the report are based on email correspondence which is unsuitable for sharing
ORCID EPrints Implementation Survey Analysis
This report explores the results of a survey of users on their requirements and plans for integrating ORCID functionality into EPrints repository software. The community was invited to share their use cases, and an online survey based on this information was conducted to determine the priorities and needs of the wider community
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry.
Hepatitis C virus (HCV) is an enveloped positive-stranded RNA hepatotropic virus. HCV pseudoparticles infect liver-derived cells, supporting a model in which liver-specific molecules define HCV internalization. Three host cell molecules have been reported to be important entry factors or receptors for HCV internalization: scavenger receptor BI, the tetraspanin CD81, and the tight junction protein claudin-1 (CLDN1). None of the receptors are uniquely expressed within the liver, leading us to hypothesize that their organization within hepatocytes may explain receptor activity. Since CD81 and CLDN1 act as coreceptors during late stages in the entry process, we investigated their association in a variety of cell lines and human liver tissue. Imaging techniques that take advantage of fluorescence resonance energy transfer (FRET) to study protein-protein interactions have been developed. Aequorea coerulescens green fluorescent protein- and Discosoma sp. red-monomer fluorescent protein-tagged forms of CD81 and CLDN1 colocalized, and FRET occurred between the tagged coreceptors at comparable frequencies in permissive and nonpermissive cells, consistent with the formation of coreceptor complexes. FRET occurred between antibodies specific for CD81 and CLDN1 bound to human liver tissue, suggesting the presence of coreceptor complexes in liver tissue. HCV infection and treatment of Huh-7.5 cells with recombinant HCV E1-E2 glycoproteins and anti-CD81 monoclonal antibody modulated homotypic (CD81-CD81) and heterotypic (CD81-CLDN1) coreceptor protein association(s) at specific cellular locations, suggesting distinct roles in the viral entry process
One-pot synthesis of micron-sized polybetaine particles: innovative use of supercritical carbon dioxide
Polybetaines exhibit unique properties combining anti-polyelectrolyte and low protein fouling behaviour, as well as biocompatibility. To date, the synthesis of polybetaine particles >50 nm has proved to be extremely challenging with standard emulsion and dispersion techniques being unsuccessful. Here we present the first reported synthesis of micron-sized, discrete cross-linked polybetaine particles, using polymerisation in scCO2 with methanol as a co-solvent. Discrete particles are produced only when the methanol is efficiently removed in situ using scCO2 extraction. A relatively high crosslinking agent initial concentration (10 wt%) was found to result in the most well defined particles, and particle integrity reduced as the crosslinking agent initial concentration was decreased. A monomer loading of between 3.0 Ă 10â2 mol Lâ1 and 1.8 Ă 10â1 mol Lâ1 resulted in discrete micron sized particles, with significant agglomoration occuring as the monomer loading was increased further. A spherical morphology and extremely low size dispersity was observed by SEM analysis for the optimised particles. The particles were readily re-dispersed in aqueous solution and light scattering measurements confirmed their low size dispersity
Education, Employment, and Americaâs Opioid Epidemic
America is embroiled in an opioid epidemic that continues to take a toll on American citizensâ quality of life, utility, and mortality rates, as well as the nationâs economy. Researchers have examined information from Substance Abuse and Mental Health Services Administrationâs (SAMHSA) Treatment Episode Data Set (TEDS) (Drug and Alcohol Services Information Systems [DASIS], 2009) in order to get an idea about which populations are able to access opioid treatment in America, the District of Columbia, and Puerto Rico. Details of education levels and employment rates for those being treated could offer answers about individuals and populations impacted by the opioid epidemic. The purpose of this study was to examine whether individuals who had been in treatment for heroin and/or opioids in 2014 have a higher level of education than individuals in treatment for heroin and/or opioids in 1998, and to determine if individuals in treatment for heroin and/or opioids in 2014 have higher rates of employment than individuals in treatment for heroin and/or opioids in 1998 (DASIS, 2009). Researchers used a T-test on the TEDS and found statistically significant changes in levels of education and static rates of employment from 1998 to 2014 (DASIS, 2009)
Autophenomenography and martial arts: future directions for practitioner research, Etnografia e Ricerca Qualitativa / Ethnography and Qualitative Research, Bergamo, Italy, June 7-8.
The various senses, including the classical five (sight, sound, smell, touch and taste) of Greco-Roman thought, are key to contemporary ethnography and other evolving qualitative research traditions. The sociology and anthropology of sport have made advances to the understanding of everyday and exceptional bodily experience,
and this has extended to the field of martial arts and combat sports, as well as other bodily arts. This paper explores the novel and ever-evolving use of the method known as auto/phenomenography, which connects to approaches in autoethnography. Drawing on the pioneering work of Allen Collinson and Hockey, as well as that of
their collaborators, we first examine the nature of what auto/phenomenography entails as a unique form of automethodology through field notes, reflections, audio recordings and also photography and other visual methods. Following this introduction, we consider some of the recent studies using this first-person, longitudinal design in the martial arts and other fighting systems
The production of Necator americanus larvae for use in experimental human infection
Background: Although there is unprecedented interest in experimental human hookworm infection, details of hookworm manufacture and characterisation have been sparsely reported. In this report, we detail the production and characterisation of Necator americanus larvae for use in a recently published clinical trial.
Methods: Faeces was obtained from an experimentally infected donor. Faecal hookworm DNA was determined by quantitative PCR. Paired samples were incubated in either sterile water or sterile water mixed with antimicrobials (amphotericin and gentamicin). Coproculture was performed by modified Harada-Mori method. The harvested larvae were then processed in either sterile water or antiseptic solution. Larval yield was then calculated (larvae per gram), larval viability was determined by thermally induced motility assay and microbial burden was determined at the day of harvest, at 48 h and at 7 days.
Results: Twenty-eight faecal cultures were performed over 16 months. The faecal hookworm DNA content was variable over this time. There was no association of larval yield with faecal hookworm DNA content. Pre-treatment of faeces with antimicrobials did not influence larval yield. Larval motility was 85.3% (95% CI 79.3â91.3%). Incubation of larvae in antiseptics did not reduce viability at 14 days with a marginal mean of 68.6% (95% CI 59.1â78.1%) washed in water vs. 63.3% (95% CI 53.8 â 72.9%) when incubated in betadine (pâ=â0.38). Larvae washed in sterile water did not meet microbial bioburden criteria. Incubation in antiseptic resulted in acceptable microbial bioburden at 48 h but not at 7 days. Although the addition of gentamicin did reduce the microbial bio-burden acceptable levels, it was found to significantly lower larval motility at 7 days compared to incubation in sterile water and motility at 7 days 37.8% (95% CI 4.7â70.9%) vs. 67.3% (95% CI 35.2â99.3%, pâ<â0.001), respectively.
Conclusions: Despite standardised culture methodologies and the use of a single donor, larval yield varied considerably between batches and had no association with faecal hookworm DNA. Larval viability decreases over time and the age of larvae at time of use are likely to be important. Microbial bioburden maybe temporarily reduced by incubation in antiseptics and has little effect on viability. Incubation of larvae in gentamicin is effective at reducing microbial bioburden but is deleterious to larval viability
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