391 research outputs found
Estimating the stability of heartbeat counting in middle childhood: a twin study
There is growing interest in interoception, the perception of the body’s internal state, and its relevance for health across development. Most evidence linking interoception to health has used the heartbeat counting task. However, the temporal stability of the measure, particularly during childhood, and the etiological factors that underlie stability, remain largely unexamined. Using data from the ECHO twin sample we estimated the magnitude of genetic and environmental influences on the stability of heartbeat counting across two years (age 8-10), the longest timeframe examined. Heartbeat counting accuracy was modestly correlated across time, (r=.35), and accuracy improved with age. Non-shared environmental factors accounted for the most variance at both time points and were the main contributors to temporal stability of heartbeat counting. Future research should seek to identify these non-shared environmental factors and elucidate whether this relatively modest stability reflects variability of interoception across development or unreliability of the heartbeat counting task
Tracing chemical evolution over the extent of the Milky Way's Disk with APOGEE Red Clump Stars
We employ the first two years of data from the near-infrared, high-resolution
SDSS-III/APOGEE spectroscopic survey to investigate the distribution of
metallicity and alpha-element abundances of stars over a large part of the
Milky Way disk. Using a sample of ~10,000 kinematically-unbiased red-clump
stars with ~5% distance accuracy as tracers, the [alpha/Fe] vs. [Fe/H]
distribution of this sample exhibits a bimodality in [alpha/Fe] at intermediate
metallicities, -0.9<[Fe/H]<-0.2, but at higher metallicities ([Fe/H]=+0.2) the
two sequences smoothly merge. We investigate the effects of the APOGEE
selection function and volume filling fraction and find that these have little
qualitative impact on the alpha-element abundance patterns. The described
abundance pattern is found throughout the range 5<R<11 kpc and 0<|Z|<2 kpc
across the Galaxy. The [alpha/Fe] trend of the high-alpha sequence is
surprisingly constant throughout the Galaxy, with little variation from region
to region (~10%). Using simple galactic chemical evolution models we derive an
average star formation efficiency (SFE) in the high-alpha sequence of ~4.5E-10
1/yr, which is quite close to the nearly-constant value found in
molecular-gas-dominated regions of nearby spirals. This result suggests that
the early evolution of the Milky Way disk was characterized by stars that
shared a similar star formation history and were formed in a well-mixed,
turbulent, and molecular-dominated ISM with a gas consumption timescale (1/SFE)
of ~2 Gyr. Finally, while the two alpha-element sequences in the inner Galaxy
can be explained by a single chemical evolutionary track this cannot hold in
the outer Galaxy, requiring instead a mix of two or more populations with
distinct enrichment histories.Comment: 18 pages, 17 figures. Accepted for publication in Ap
Formation and Evolution of the Disk System of the Milky Way: [alpha/Fe] Ratios and Kinematics of the SEGUE G-Dwarf Sample
We employ measurements of the [alpha/Fe] ratio derived from low-resolution
(R~2000) spectra of 17,277 G-type dwarfs from the SEGUE survey to separate them
into likely thin- and thick-disk subsamples. Both subsamples exhibit strong
gradients of orbital rotational velocity with metallicity, of opposite signs,
-20 to -30 km/s/dex for the thin-disk and +40 to +50 km/s/dex for the
thick-disk population. The rotational velocity is uncorrelated with
Galactocentric distance for the thin-disk subsample, and exhibits a small trend
for the thick-disk subsample. The rotational velocity decreases with distance
from the plane for both disk components, with similar slopes (-9.0 {\pm} 1.0
km/s/kpc). Thick-disk stars exhibit a strong trend of orbital eccentricity with
metallicity (about -0.2/dex), while the eccentricity does not change with
metallicity for the thin-disk subsample. The eccentricity is almost independent
of Galactocentric radius for the thin-disk population, while a marginal
gradient of the eccentricity with radius exists for the thick-disk population.
Both subsamples possess similar positive gradients of eccentricity with
distance from the Galactic plane. The shapes of the eccentricity distributions
for the thin- and thick-disk populations are independent of distance from the
plane, and include no significant numbers of stars with eccentricity above 0.6.
Among several contemporary models of disk evolution we consider, radial
migration appears to have played an important role in the evolution of the
thin-disk population, but possibly less so for the thick disk, relative to the
gas-rich merger or disk heating scenarios. We emphasize that more physically
realistic models and simulations need to be constructed in order to carry out
the detailed quantitative comparisons that our new data enable.Comment: Accepted for publication in ApJ, 18 pages, 12 figures, 2 tables,
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Atypical Social Modulation of Imitation in Autism Spectrum Conditions.
Appropriate modulation of imitation according to social context is important for successful social interaction. In the present study we subliminally primed high-functioning adults with ASC and age- and IQ-matched controls with either a pro- or non- social attitude. Following priming, an automatic imitation paradigm was used to acquire an index of imitation. Whereas imitation levels were higher for pro-socially primed relative to non-socially primed control participants, there was no difference between pro- and non- socially primed individuals with ASC. We conclude that high-functioning adults with ASC demonstrate atypical social modulation of imitation. Given the importance of imitation in social interaction we speculate that difficulties with the modulation of imitation may contribute to the social problems characteristic of ASC
The Apache Point Observatory Galactic Evolution Experiment: First Detection of High Velocity Milky Way Bar Stars
Commissioning observations with the Apache Point Observatory Galactic
Evolution Experiment (APOGEE), part of the Sloan Digital Sky Survey III, have
produced radial velocities (RVs) for ~4700 K/M-giant stars in the Milky Way
bulge. These high-resolution (R \sim 22,500), high-S/N (>100 per resolution
element), near-infrared (1.51-1.70 um; NIR) spectra provide accurate RVs
(epsilon_v~0.2 km/s) for the sample of stars in 18 Galactic bulge fields
spanning -1-32 deg. This represents the largest
NIR high-resolution spectroscopic sample of giant stars ever assembled in this
region of the Galaxy. A cold (sigma_v~30 km/s), high-velocity peak (V_GSR \sim
+200 km/s) is found to comprise a significant fraction (~10%) of stars in many
of these fields. These high RVs have not been detected in previous MW surveys
and are not expected for a simple, circularly rotating disk. Preliminary
distance estimates rule out an origin from the background Sagittarius tidal
stream or a new stream in the MW disk. Comparison to various Galactic models
suggests that these high RVs are best explained by stars in orbits of the
Galactic bar potential, although some observational features remain
unexplained.Comment: 7 pages, 4 figures, accepted for publication in ApJ Letter
Real Potential
There\u27s a student in my philosophy class who has real potential. I might express this thought in any of the following ways: She is potentially a philosopher ; She is a potential philosopher ; She has the potential to be a philosopher. The first way uses a cognate of potential as an adverb to modify is. The second ways uses potential as an adjective to modify philosopher. However, the third way uses potential as a noun to refer to something that the student has. What kind of thing is this potential? One worry about even asking this question is that this nominalization of the adjective potential suggests a metaphysical picture that is an artifact of language. This is even more strongly suggested by the less ambiguous nominalization potentiality. Once we have the term potentiality, we have a new kind of entity to countenance, and questions about its nature arise. One might argue, just because we use the word potentiality, we should not think that it refers to a thing that someone can have.
There is something disingenuous about such an argument. It proceeds as if the adverbial and adjectival uses of potential are unproblematic, and questions only arise with the nominalization. But it is not obvious what it means to potentially be something, or what it means to be a potential something. To say that someone is potentially a philosopher is to talk about a way of being that falls short of actuality. And a potential philosopher is not a kind of philosopher at all. So what is it? Each of the three above formulations is a modal claim. If there is anything philosophical puzzling about a potentiality claim, it is not going to go away by translating it into an equivalent modal claim.
In this chapter I defend the existence of potentialities against anti-realist arguments, and make a proposal as to their nature. The proposal, in short, is that potentialities are properties, specifically dispositions, though more needs to be said about properties and dispositions. I will do this in Part I. In Part II, I will address two lines of argument against potentialities: that they are reducible, and that they are causally inert
Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a predominantly female autoimmune disease that affects multiple organ systems. Herein, we report on an X-chromosome gene association with SLE. Methyl-CpG-binding protein 2 (MECP2) is located on chromosome Xq28 and encodes for a protein that plays a critical role in epigenetic transcriptional regulation of methylation-sensitive genes. Utilizing a candidate gene association approach, we genotyped 21 SNPs within and around MECP2 in SLE patients and controls. We identify and replicate association between SLE and the genomic element containing MECP2 in two independent SLE cohorts from two ethnically divergent populations. These findings are potentially related to the overexpression of methylation-sensitive genes in SLE
SDSS-IV from 2014 to 2016: A Detailed Demographic Comparison over Three Years
The Sloan Digital Sky Survey (SDSS) is one of the largest international
astronomy organizations. We present demographic data based on surveys of its
members from 2014, 2015 and 2016, during the fourth phase of SDSS (SDSS-IV). We
find about half of SDSS-IV collaboration members were based in North America, a
quarter in Europe, and the remainder in Asia and Central and South America.
Overall, 26-36% are women (from 2014 to 2016), up to 2% report non-binary
genders. 11-14% report that they are racial or ethnic minorities where they
live. The fraction of women drops with seniority, and is also lower among
collaboration leadership. Men in SDSS-IV were more likely to report being in a
leadership role, and for the role to be funded and formally recognized. SDSS-IV
collaboration members are twice as likely to have a parent with a college
degree, than the general population, and are ten times more likely to have a
parent with a PhD. This trend is slightly enhanced for female collaboration
members. Despite this, the fraction of first generation college students (FGCS)
is significant (31%). This fraction increased among collaboration members who
are racial or ethnic minorities (40-50%), and decreased among women (15-25%).
SDSS-IV implemented many inclusive policies and established a dedicated
committee, the Committee on INclusiveness in SDSS (COINS). More than 60% of the
collaboration agree that the collaboration is inclusive; however, collaboration
leadership more strongly agree with this than the general membership. In this
paper, we explain these results in full, including the history of inclusive
efforts in SDSS-IV. We conclude with a list of suggested recommendations based
on our findings, which can be used to improve equity and inclusion in large
astronomical collaborations, which we argue is not only moral, but will also
optimize their scientific output.Comment: 30 pages, 9 figures, accepted in PAS
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