Modelo conceptual de un SIG gerencial para el manejo de la información espacial en el área ambiental de la central hidroeléctrica Manduriacu

The large volume of spatial data generated around the environmental management of a hydroelectric project creates the need for implementing a geographic information system that enables the management of spatial data to serve as a support for environmental management and further as a tool for planning and decision making. Geographic Information Systems allow not only for a support at the conceptual level structuring management tasks, but also at the organizational level. For this reason the present thesis aims to investigate the reach of GIS methodologies beyond a design for a conceptual model of spatial data management, and provide the guidelines for the administration and creation of a technical unit that is proposed to be capable of meeting the needs of internal users regarding the identified environmental management tasks related to GIS for the hydropower project.El gran volumen de información espacial que se genera en el área ambiental de un proyecto Hidroeléctrico crea la necesidad de implementar un sistema de información geográfica que permita el manejo de los datos espaciales para que sirvan de soporte a la Gerencia ambiental y ayudar a que este sea una herramienta de planificación y toma de decisiones. Los Sistemas de información geográfico permiten llegar a esos niveles siempre que se tenga una estructura de manejo no solo a nivel conceptual si no a nivel organizacional, por esta razón el presente trabajo pretende llegar a no solo plantear un modelo conceptual de almacenamiento de información, si no también dar las directrices de la administración y creación de una unidad capaz de atender las necesidades de los clientes internos de la Gerencia Ambiental

Cualificación docente en habilidades blandas como factor de mejora de la gestión escolar en tres Instituciones Educativas Rurales de Montería

The objective of this research is to optimize the learning of soft skills in the teachers of the Rural Educational Institutions of the city of Montería Córdoba. Which are official. Based on a quantitative approach, of a Pre-experimental type with an Experimental design. The selected sample will be primary and secondary teachers, both provisional and owned by three (3) rural educational institutions: IE Santa Fe, IE San José de Jaraquiel and IE Pueblo Bujo. This research seeks to implement a soft skills training model in teachers that allows them to develop dynamically and intuitively and that can be the constant support of the student. The research gives rise to the further development of soft skills in students in the future and serves as a basis for future research.La presente investigación tiene como objetivo optimizar el aprendizaje en habilidades blandas en los docentes de las Instituciones Educativas Rurales de  la ciudad de Montería Córdoba. Las cuales son de carácter oficial. Con base a un enfoque cuantitativo,  de tipo Pre- experimental con diseño  Experimental. La muestra seleccionada serán los docentes de  primaria y secundaria, tanto provisionales  como en propiedad de tres, (3) instituciones educativas rurales: IE Santa Fe, IE San José de Jaraquiel y IE Pueblo Bujo. Con esta investigación se busca implementar un modelo de formación en habilidades blandas en los docentes que  les permita desarrollarse de manera dinámica e intuitiva  y que puedan ser el apoyo constante del educando.  La investigación da pie a que, en el futuro, se profundice el desarrollo de las habilidades blandas en los estudiantes y sirva de base para futuras investigaciones

Cualificación docente en habilidades blandas como factor de mejora de la gestión escolar en tres Instituciones Educativas Rurales de Montería

The objective of this research is to optimize the learning of soft skills in the teachers of the Rural Educational Institutions of the city of Montería Córdoba. Which are official. Based on a quantitative approach, of a Pre-experimental type with an Experimental design. The selected sample will be primary and secondary teachers, both provisional and owned by three (3) rural educational institutions: IE Santa Fe, IE San José de Jaraquiel and IE Pueblo Bujo. This research seeks to implement a soft skills training model in teachers that allows them to develop dynamically and intuitively and that can be the constant support of the student. The research gives rise to the further development of soft skills in students in the future and serves as a basis for future research.La presente investigación tiene como objetivo optimizar el aprendizaje en habilidades blandas en los docentes de las Instituciones Educativas Rurales de  la ciudad de Montería Córdoba. Las cuales son de carácter oficial. Con base a un enfoque cuantitativo,  de tipo Pre- experimental con diseño  Experimental. La muestra seleccionada serán los docentes de  primaria y secundaria, tanto provisionales  como en propiedad de tres, (3) instituciones educativas rurales: IE Santa Fe, IE San José de Jaraquiel y IE Pueblo Bujo. Con esta investigación se busca implementar un modelo de formación en habilidades blandas en los docentes que  les permita desarrollarse de manera dinámica e intuitiva  y que puedan ser el apoyo constante del educando.  La investigación da pie a que, en el futuro, se profundice el desarrollo de las habilidades blandas en los estudiantes y sirva de base para futuras investigaciones

Diversity of clinical, radiographic and genealogical findings in 41 families with amelogenesis imperfecta

Amelogenesis imperfecta (AI) is a group of enamel development disorders that alter the structure and chemical composition of the tissue. There is great variability in the clinical presentation; according to Witkop, AI can be categorized into 14 subtypes, which makes its diagnosis extremely complex. Objective: This study aimed to describe and determine the frequency of clinical and radiographic features and inheritance patterns found in 41 Chilean families diagnosed with diverse types of AI. Material and Methods: We analyzed the clinical records, photographs, pedigrees and radiographs of 121 individuals recruited between 2003 and 2016. All of the information was included in a database that was analyzed using the application Stata 14. Results: The 72 affected individuals had average age of 16 years, and no sex association with the presence of AI was found. The most frequent clinical subtypes were as follows: 43% hypomature, 25% hypoplastic, 21% hypomature/hypoplastic, 7% hypocalcified and 4% hypocalcified/hypoplastic. The number of severely affected teeth was 22, which occurred in the patients with hypocalcified and hypocalcified/hypoplasic AI who presented the highest number of damaged teeth. Caries and periodontal disease were found in 47 and 32% of the patients, respectively. Malocclusions were observed in 43% of the individuals with AI, with open bite being the most frequent. Radiographically, the thickness of the enamel decreased in 51% of the patients, and 80% showed decreased radiopacity of the enamel compared to that of dentin. Autosomal dominant inheritance pattern was found in 37% of the families with hypoplastic AI, and autosomal recessive pattern was present in 56% of the other clinical subtypes, but more frequently in those affected with hypomature and hypocalcified AI. Conclusion: Of the five clinical subtypes, autosomal recessive hypomature, autosomal dominant hypoplastic and autosomal recessive hypomature/hypoplastic AI were the most prevalent subtypes in this group

The genetic population structure of Robinson Crusoe Island, Chile

Studies examining genetic conditions common in Latin America are highly underrepresented in the scientific literature. Understanding of the population structure is limited, particularly Chile, in part due to the lack of available population specific data. An important first-step in elucidating disease mechanisms in Latin America countries is to understand the genetic structure of isolated populations. Robinson Crusoe Island (RCI) is a small land mass off the coast of Chile. The current population of over 900 inhabitants are primarily descended from a small number of founders who colonized the island in the late 1800s. Extensive genealogical records can trace the ancestry of almost the entire population. We perform a comprehensive genetic analysis to investigate the ancestry of the island population, examining ancestral mitochondrial and Y chromosome haplogroups, as well as autosomal admixture. Mitochondrial and Y chromosome haplogroups indicated a substantial European genetic contribution to the current RCI population. Analysis of the mitochondrial haplogroups found in the present-day population revealed that 79.1% of islanders carried European haplogroups, compared to 60.0% of the mainland Chilean controls from Santiago. Both groups showed a substantially lower contribution of indigenous haplogroups than expected. Analysis of the Y chromosome haplogroups also showed predominantly European haplogroups detected in 92.3% of male islanders and 86.7% of mainland Chilean controls. Using the near-complete genealogical data collected from the RCI population, we successfully inferred the ancestral haplogroups of 16/23 founder individuals, revealing genetic ancestry from Northern and Southern Europe. As mitochondrial and Y investigations only provide information for direct maternal and paternal lineages, we expanded this to investigate genetic admixture using the autosomes. Admixture analysis identified substantial indigenous genetic admixture in the RCI population (46.9%), higher than that found in the Santiago mainland Chilean controls (43.4%), but lower than a more representative Chilean population (Chile_GRU) (49.1%). Our study revealed the Robinson Crusoe Island population show a substantial genetic contribution for indigenous Chileans, similar to the level reported in mainland Chileans. However, direct maternal and paternal haplogroup analysis revealed strong European genetic contributions consistent with the history of the Island

Association of common ATM variants with familial breast cancer in a South American population

Background: The ATM gene has been frequently involved in hereditary breast cancer as a low-penetrance susceptibility gene but evidence regarding the role of ATM as a breast cancer susceptibility gene has been contradictory. Methods: In this study, a full mutation analysis of the ATM gene was carried out in patients from 137 Chilean breast cancer families, of which 126 were BRCA1/2 negatives and 11 BRCA1/2 positives. We further perform a case-control study between the subgroup of 126 cases BRCA1/2 negatives and 200 controls for the 5557G > A missense variant and the IVS38-8T > C and the IVS24-9delT polymorphisms. Results: In the full mutation analysis we detected two missense variants and eight intronic polymorphisms. Carriers of the variant IVS24-9delT, or IVS38-8T > C, or 5557G > A showed an increase in breast cancer risk. The higher significance was observed in the carriers of IVS38-8T > C (OR = 3.09 [95% CI 1.11-8.59], p = 0.024). The IVS24-9 T/(-T), IVS38-8 T/C, 5557 G/A composite genotype confered a 3.19 fold increase in breast cancer risk (OR = 3.19 [ 95% CI 1.16-8.89], p = 0.021). The haplotype estimation suggested a strong linkage disequilibrium between the three markers (D' = 1). We detected only three haplotypes in the cases and control samples, some of these may be founder haplotypes in the Chilean population. Conclusion: The IVS24-9 T/(-T), IVS38-8 T/C, 5557 G/A composite genotype alone or in combination with certain genetic background and/or environmental factors, could modify the cancer risk by increasing genetic inestability or by altering the effect of the normal DNA damage response

Genome-wide analysis of genetic susceptibility to language impairment in an isolated Chilean population

Specific language impairment (SLI) is an unexpected deficit in the acquisition of language skills and affects between 5 and 8% of pre-school children. Despite its prevalence and high heritability, our understanding of the aetiology of this disorder is only emerging. In this paper, we apply genome-wide techniques to investigate an isolated Chilean population who exhibit an increased frequency of SLI. Loss of heterozygosity (LOH) mapping and parametric and non-parametric linkage analyses indicate that complex genetic factors are likely to underlie susceptibility to SLI in this population. Across all analyses performed, the most consistently implicated locus was on chromosome 7q. This locus achieved highly significant linkage under all three non-parametric models (max NPL=6.73, P=4.0 × 10−11). In addition, it yielded a HLOD of 1.24 in the recessive parametric linkage analyses and contained a segment that was homozygous in two affected individuals. Further, investigation of this region identified a two-SNP haplotype that occurs at an increased frequency in language-impaired individuals (P=0.008). We hypothesise that the linkage regions identified here, in particular that on chromosome 7, may contain variants that underlie the high prevalence of SLI observed in this isolated population and may be of relevance to other populations affected by language impairments

Comprensión lectora 1 : cuaderno de trabajo para estudiantes de primer grado de Secundaria 2018

Cuaderno de trabajo sobre comprensión lectora para estudiantes de primer grado de Secundaria. Texto para el año escolar 2018

LA U INVESTIGA: Revista Científica. Facultad Ciencias de la Salud. Volumen 2. Número 1

La revista científica La U investiga de la Facultad Ciencias de la Salud tiene como objetivo difundir los resultados de investigaciones realizadas por estudiantes y profesionales de la salud nacionales e internacionales a través de artículos científicos; que permitan generar nuevos conocimientos y aportar en la solución de los problemas de salud de la población.• Evaluación del riesgo individual ergonómico en el Personal administrativo de empresas públicas de La provincia de Imbabura. • Importancia de la determinación de la hemoglobina Glicocilada como desencadenante de tratamiento Preventivo contra la diabetes mellitus tipo 2. • Factores predisponentes para sustitución renal en pacientes dializados en el hospital San Vicente De Paúl – Ibarra. • Evolución del hijo de madre adolescente. Hospital Enrique Cabrera - julio del 2011 julio del 2012. • Relación del control de tronco con actividades de la vida diaria en pacientes con accidente cerebro vascular del Hospital San Vicente De Paúl. • Manejo laparoscópico de un quiste hepático simple recidivante. • Tumor fibroso solitario pleural. reporte de un cas