To What Extent Did Assumptions About Local Ethnic Identities, Fostered Amongst UN Officials During the Bosnia Mission, Frame Their Policies for the Kosovo Mission?

This thesis focuses on the role of an international actor - United Nations (UN) - and its missions in Bosnia and Herzegovina (UNMBiH) during 1992-1995 and Kosovo (UNMIK) in the post war conflict period of peace building. It scrutinizes the tenor of UN peace building missions in these territories by analysing the scope of the policies introduced and the effectiveness (or ineffectiveness) of the international actors' activities during the times of war in Bosnia and Herzegovina (BiH) before the conflict in Kosovo and Metohija (KiM); and the current situation in these two territories. The thesis will also argue that the ethnic identities played a critical role in relation building between the UN and ethnic groups, where the one ethnic group (Serbs) was recognised as a crucial factor for the conflict's escalation and development. A further focus in this thesis is not only to provide constructive discussion of the ineffectiveness of policies and missions introduced by International Actors (IA) but also to challenge the UN and IA's decision for non-intervention in BiH and to address the consequence of subsequent humanitarian-military intervention in KiM. This paper outlines an analysis of the lack of literature relating to the historical-sociological perspective of the ethnic groups' in BiH. The lack of understanding of the complex relationships among the ethnicities is an additional gap. This is exacerbated by the lack of understanding of the complex relationships among the ethnicities, within itself, as well as the differences among the groups within each ethnic group. It appears that the literature is unable to acknowledge the structural formation of societies in BiH, and to make proper segmentation in understanding the particular group of people (Rex, 2001) as a collection of peoples with different sociological characteristics combined into something called 'ethnicity'. The handicap of such literature leads to the categorisation and generalisation of ethnicities; not at one particular area of an ethnic group's presence but to the generalisation of the peoples' ethnicities (all Serbs are barbarous, similar to the Germans after WWII). This paper argues that such generalisations developed the notion that the particular ethnic group (Serbs) has an 'evil' character, regardless of the territorial occupation (Bosnia as well as Serbia and Diaspora). In addition, the lack of recognising Serbs as a people composed of different individual (local) ethnic groups led to the global generalisation about Serbs. And yet, such generalisations, by the modern western actors, i.e. UN, EU (European Union) and USA (United States of America), led to the employment of negative assumptions about the Serbs which served as a tool for, and added impetus to, the implementation of a strategy to achieve the Western objectives of the devaluation of Serbian dominance in Bosnia and across the Balkan Peninsula. Therefore the quality of literature, in addressing the questions about the conflict in BiH and later KiM, beside its attempts to offer some sustainable answers, remains inadequate and poor. This unsubstantiated position, offered by many involved in former-Yugoslavian conflict discussions, to offer an informed conclusion, persists as a never-ending debate. Yet, the discourse about the guilty factor in BiH and KiM remains in the shape of the 'evil' Serbian nation

EFFECT OF SIMVASTATIN TREATMENT ON BONE MINERAL DENSITY IN HYPERCHOLESTEROLEMIC POSTMENOPAUSAL WOMEN

Statins are able to reduce cardiovascular morbidity and mortality mainly through their hypocholesterolemic effect. Beyond the inhibition of cholesterol synthesis, the identification of pleiotropic mechanisms has motivated many studies to evaluate the effects of statin use on bone mineral density (BMD) modification.The aim of our study was to evaluate whether simvastatin treatment (20 mg/d) could modify BMD in hypercholesterolemic women (n=28) after one-year treatment as compared with a control group treated only with a diet (n=11). The exclusion criteria was current or previous therapy with statins, bisphosphonates and/or estrogens. The following parameters were determined at the beginning and after one year, and those are: total cholesterol, triglycerides, HDL-C and LDL-C (Friedewald equation). The BMD was measured at the lumbar spine by dual energy x-ray absorpiometry (DEXA).In the simvastatin treated group, BMD showed an insignificant 2,812% increase after 12 months, respectively (0,965+0,111 v 0,992+0,110, P>0,05). The group treated only with hypolipidic diet demonstrated a 3,45% decrease in BMD (respectively, 1,042+0,181 v 1.006+0,182; P>0,05) after 12 months. Nevertheless, the comparison of average BMD changes between the two examined groups during one year showed a significant value diference (-0,027+0,037 v 0,036+0,036; P<0,0006).As partly suggested by retrospective or observational data, this longitudinal study indicates that simvastatin treatment achieves a beneficial effect on BMD

SUSTAINABLE DEVELOPMENT OF TRUST AND POLICE PRESENCE IN SCHOOLS: IMPLICATIONS FOR SCHOOL SAFETY POLICY

The study aims to determine the trust and presence of police officers in schools in Serbia, as well as the perception of the principals and secretaries, teachers and staff, parents, and students on how successful the specific police units dedicated to schools were in fulfilling their tasks. The ex-post analysis was conducted through PEST/SWAT analysis, mapping the key actors and using batteries of online questionnaires, besides interviews with the MOI representatives, surveyed with personal interviewing, computer-aided surveying, desk analysis, and content analysis. The survey was conducted from September 2021 to June 2022. The research methods were implemented in 1140 schools in Serbia, and 8,617 people were included in surveys: police officers (308); principals and secretaries (1085); the team for protection against discrimination (982); teachers and staff (2988); parents (938) and students (2316). The relationships between the covariates and perception were investigated using the t-test, one-way ANOVA, multivariate linear regression, and binary regression. The results showed that a project of school police officers was not fully recognized as one of the strategically essential instruments for safe schools; trust is low, but presence is high. Besides that, the results suggest that the entire public believes that police are needed in schools and that it positively affects school safety. Regarding school safety policy, it is necessary to undertake three measures for the sustainable development of trust and the presence of police in school: regulatory, informative-educational, and institutional-organizational.

Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies

We developed new iminosugar-based glycosidase inhibitors against SARS-CoV-2. Known drugs (miglustat, migalastat, miglitol, and swainsonine) were chosen as lead compounds to develop three classes of glycosidase inhibitors (α-glucosidase, α-galactosidase, and mannosidase). Molecular modelling of the lead compounds, synthesis of the compounds with the highest docking scores, enzyme inhibition tests, and in vitro antiviral assays afforded rationally designed inhibitors. Two highly active α-glucosidase inhibitors were discovered, where one of them is the most potent iminosugar-based anti-SARS-CoV-2 agent to date (EC90 = 1.94 µM in A549-ACE2 cells against Omicron BA.1 strain). However, galactosidase inhibitors did not exhibit antiviral activity, whereas mannosidase inhibitors were both active and cytotoxic. As our iminosugar-based drug candidates act by a host-directed mechanism, they should be more resilient to drug resistance. Moreover, this strategy could be extended to identify potential drug candidates for other viral infections

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

To What Extent Did Assumptions About Local Ethnic Identities, Fostered Amongst UN Officials During the Bosnia Mission, Frame Their Policies for the Kosovo Mission?

This thesis focuses on the role of an international actor - United Nations (UN) - and its missions in Bosnia and Herzegovina (UNMBiH) during 1992-1995 and Kosovo (UNMIK) in the post war conflict period of peace building. It scrutinizes the tenor of UN peace building missions in these territories by analysing the scope of the policies introduced and the effectiveness (or ineffectiveness) of the international actors' activities during the times of war in Bosnia and Herzegovina (BiH) before the conflict in Kosovo and Metohija (KiM); and the current situation in these two territories. The thesis will also argue that the ethnic identities played a critical role in relation building between the UN and ethnic groups, where the one ethnic group (Serbs) was recognised as a crucial factor for the conflict's escalation and development. A further focus in this thesis is not only to provide constructive discussion of the ineffectiveness of policies and missions introduced by International Actors (IA) but also to challenge the UN and IA's decision for non-intervention in BiH and to address the consequence of subsequent humanitarian-military intervention in KiM. This paper outlines an analysis of the lack of literature relating to the historical-sociological perspective of the ethnic groups' in BiH. The lack of understanding of the complex relationships among the ethnicities is an additional gap. This is exacerbated by the lack of understanding of the complex relationships among the ethnicities, within itself, as well as the differences among the groups within each ethnic group. It appears that the literature is unable to acknowledge the structural formation of societies in BiH, and to make proper segmentation in understanding the particular group of people (Rex, 2001) as a collection of peoples with different sociological characteristics combined into something called 'ethnicity'. The handicap of such literature leads to the categorisation and generalisation of ethnicities; not at one particular area of an ethnic group's presence but to the generalisation of the peoples' ethnicities (all Serbs are barbarous, similar to the Germans after WWII). This paper argues that such generalisations developed the notion that the particular ethnic group (Serbs) has an 'evil' character, regardless of the territorial occupation (Bosnia as well as Serbia and Diaspora). In addition, the lack of recognising Serbs as a people composed of different individual (local) ethnic groups led to the global generalisation about Serbs. And yet, such generalisations, by the modern western actors, i.e. UN, EU (European Union) and USA (United States of America), led to the employment of negative assumptions about the Serbs which served as a tool for, and added impetus to, the implementation of a strategy to achieve the Western objectives of the devaluation of Serbian dominance in Bosnia and across the Balkan Peninsula. Therefore the quality of literature, in addressing the questions about the conflict in BiH and later KiM, beside its attempts to offer some sustainable answers, remains inadequate and poor. This unsubstantiated position, offered by many involved in former-Yugoslavian conflict discussions, to offer an informed conclusion, persists as a never-ending debate. Yet, the discourse about the guilty factor in BiH and KiM remains in the shape of the 'evil' Serbian nation

To What Extent Did Assumptions About Local Ethnic Identities, Fostered Amongst UN Officials During the Bosnia Mission, Frame Their Policies for the Kosovo Mission?

This thesis focuses on the role of an international actor - United Nations (UN) - and its missions in Bosnia and Herzegovina (UNMBiH) during 1992-1995 and Kosovo (UNMIK) in the post war conflict period of peace building. It scrutinizes the tenor of UN peace building missions in these territories by analysing the scope of the policies introduced and the effectiveness (or ineffectiveness) of the international actors' activities during the times of war in Bosnia and Herzegovina (BiH) before the conflict in Kosovo and Metohija (KiM); and the current situation in these two territories. The thesis will also argue that the ethnic identities played a critical role in relation building between the UN and ethnic groups, where the one ethnic group (Serbs) was recognised as a crucial factor for the conflict's escalation and development. A further focus in this thesis is not only to provide constructive discussion of the ineffectiveness of policies and missions introduced by International Actors (IA) but also to challenge the UN and IA's decision for non-intervention in BiH and to address the consequence of subsequent humanitarian-military intervention in KiM. This paper outlines an analysis of the lack of literature relating to the historical-sociological perspective of the ethnic groups' in BiH. The lack of understanding of the complex relationships among the ethnicities is an additional gap. This is exacerbated by the lack of understanding of the complex relationships among the ethnicities, within itself, as well as the differences among the groups within each ethnic group. It appears that the literature is unable to acknowledge the structural formation of societies in BiH, and to make proper segmentation in understanding the particular group of people (Rex, 2001) as a collection of peoples with different sociological characteristics combined into something called 'ethnicity'. The handicap of such literature leads to the categorisation and generalisation of ethnicities; not at one particular area of an ethnic group's presence but to the generalisation of the peoples' ethnicities (all Serbs are barbarous, similar to the Germans after WWII). This paper argues that such generalisations developed the notion that the particular ethnic group (Serbs) has an 'evil' character, regardless of the territorial occupation (Bosnia as well as Serbia and Diaspora). In addition, the lack of recognising Serbs as a people composed of different individual (local) ethnic groups led to the global generalisation about Serbs. And yet, such generalisations, by the modern western actors, i.e. UN, EU (European Union) and USA (United States of America), led to the employment of negative assumptions about the Serbs which served as a tool for, and added impetus to, the implementation of a strategy to achieve the Western objectives of the devaluation of Serbian dominance in Bosnia and across the Balkan Peninsula. Therefore the quality of literature, in addressing the questions about the conflict in BiH and later KiM, beside its attempts to offer some sustainable answers, remains inadequate and poor. This unsubstantiated position, offered by many involved in former-Yugoslavian conflict discussions, to offer an informed conclusion, persists as a never-ending debate. Yet, the discourse about the guilty factor in BiH and KiM remains in the shape of the 'evil' Serbian nation.</p