465 research outputs found
Scientific CCD technology at JPL
Charge-coupled devices (CCD's) were recognized for their potential as an imaging technology almost immediately following their conception in 1970. Twenty years later, they are firmly established as the technology of choice for visible imaging. While consumer applications of CCD's, especially the emerging home video camera market, dominated manufacturing activity, the scientific market for CCD imagers has become significant. Activity of the Jet Propulsion Laboratory and its industrial partners in the area of CCD imagers for space scientific instruments is described. Requirements for scientific imagers are significantly different from those needed for home video cameras, and are described. An imager for an instrument on the CRAF/Cassini mission is described in detail to highlight achieved levels of performance
Electrode level Monte Carlo model of radiation damage effects on astronomical CCDs
Current optical space telescopes rely upon silicon Charge Coupled Devices
(CCDs) to detect and image the incoming photons. The performance of a CCD
detector depends on its ability to transfer electrons through the silicon
efficiently, so that the signal from every pixel may be read out through a
single amplifier. This process of electron transfer is highly susceptible to
the effects of solar proton damage (or non-ionizing radiation damage). This is
because charged particles passing through the CCD displace silicon atoms,
introducing energy levels into the semi-conductor bandgap which act as
localized electron traps. The reduction in Charge Transfer Efficiency (CTE)
leads to signal loss and image smearing. The European Space Agency's
astrometric Gaia mission will make extensive use of CCDs to create the most
complete and accurate stereoscopic map to date of the Milky Way. In the context
of the Gaia mission CTE is referred to with the complementary quantity Charge
Transfer Inefficiency (CTI = 1-CTE). CTI is an extremely important issue that
threatens Gaia's performances. We present here a detailed Monte Carlo model
which has been developed to simulate the operation of a damaged CCD at the
pixel electrode level. This model implements a new approach to both the charge
density distribution within a pixel and the charge capture and release
probabilities, which allows the reproduction of CTI effects on a variety of
measurements for a large signal level range in particular for signals of the
order of a few electrons. A running version of the model as well as a brief
documentation and a few examples are readily available at
http://www.strw.leidenuniv.nl/~prodhomme/cemga.php as part of the CEMGA java
package (CTI Effects Models for Gaia).Comment: Accepted by MNRAS on 13 February 2011. 15 pages, 7 figures and 5
table
Sub-electron noise charge-coupled devices
A charge coupled device designed for celestial spectroscopy has achieved readout noise as low as 0.6 electrons rms. A nondestructive output circuit was operated in a special manner to read a single pixel multiple times. Off-chip electronics averaged the multiple values, reducing the random noise by the square root of the number of readouts. Charge capacity was measured to be 500,000 electrons. The device format is 1600 pixels horizontal by 64 pixels vertical. Pixel size is 28 microns square. Two output circuits are located at opposite ends of the 1600 bit CCD register. The device was thinned and operated backside illuminated at -110 degrees C. Output circuit design, layout, and operation are described. Presented data includes the photon transfer curve, noise histograms, and bar-target images down to 3 electrons signal. The test electronics are described, and future improvements are discussed
Detection of sub-shot-noise spatial correlation in high-gain parametric down-conversion
Using a 1GW-1ps pump laser pulse in high gain parametric down-conversion
allows us to detect sub-shot-noise spatial quantum correlation with up to one
hundred photoelectrons per mode, by means of a high efficiency CCD. The
statistics is performed in single-shot over independent spatial replica of the
system. The paper highlights the evidence of quantum correlation between
symmetrical signal and idler spatial areas in the far field, in the high gain
regime. In accordance with the predictions of numerical calculations the
observed transition from the quantum to the classical regime is interpreted as
a consequence of the narrowing of the down-converted beams in the very high
gain regime.Comment: 4,2 pages, 4 figure
Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47
Recent studies suggest that exposure to endocrine-disrupting compounds (EDCs) may play a role in the development of obesity. EDCs such as the flame retardant 2,2′,4,4′-tetrabrominated diphenyl ether (BDE-47) have been shown to enhance adipocyte differentiation in the murine 3T3-L1 model. The mechanisms by which EDCs direct preadipocytes to form adipocytes are poorly understood. Here, we examined transcriptional and epigenetic mechanisms underlying the induction of in vitro adipocyte differentiation by BDE-47. Quantitative high content microscopy revealed concentration-dependent enhanced adipocyte differentiation following exposure to BDE-47 or the antidiabetic drug troglitazone (TROG). BDE-47 modestly activated the key adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARγ) in COS7 cells, transiently transfected with a GAL4 reporter construct. Increased gene expression was observed for Pparγ2, leptin (Lep), and glucose-6-phophatase catalytic subunit (G6pc) in differentiated 3T3-L1 cells after BDE-47 exposure compared to TROG.
Methylation-sensitive high resolution melting (MS-HRM) revealed significant demethylation of three CpG sites in the Pparγ2 promoter after exposure to both BDE-47 and TROG in differentiated 3T3-L1 cells. This study shows the potential of BDE-47 to
induce adipocyte differentiation through various mechanisms that include Pparγ2 gene induction and promoter demethylation accompanied by activation of PPARγ, and possible disruption of glucose homeostasis and IGF1 signaling
Development of EM-CCD-based X-ray detector for synchrotron applications
A high speed, low noise camera system for crystallography and X-ray imaging applications is developed and successfully demonstrated. By coupling an electron-multiplying (EM)-CCD to a 3:1 fibre-optic taper and a CsI(Tl) scintillator, it was possible to detect hard X-rays. This novel approach to hard X-ray imaging takes advantage of sub-electron equivalent readout noise performance at high pixel readout frequencies of EM-CCD detectors with the increase in the imaging area that is offered through the use of a fibre-optic taper. Compared with the industry state of the art, based on CCD camera systems, a high frame rate for a full-frame readout (50 ms) and a lower readout noise (<1 electron root mean square) across a range of X-ray energies (6–18 keV) were achieved
New advancements in charge-coupled device technology: sub-electron noise and 4096x4096 pixel CCDs
This paper reports on two new advancements in CCD technology. The first area of development has produced a special purpose CCD designed for ultra low-signal level imaging and spectroscopy applications that require sub-electron read noise floors. A nondestructive output circuit operating near its 1/f noise regime is clocked in a special manner to read a single pixel multiple times. Off-chip electronics average the multiple values, reducing the random noise by the square-root of the number of samples taken. Noise floors below 0.5 electrons rms are reported. The second development involves the design and performance of a high resolution imager of 4096 x 4096 pixels, the largest CCD manufactured in terms of pixel count. The device utilizes a 7.5-micron pixel fabricated with three-level poly-silicon to achieve high yield
Background Rejection in the DMTPC Dark Matter Search Using Charge Signals
The Dark Matter Time Projection Chamber (DMTPC) collaboration is developing
low-pressure gas TPC detectors for measuring WIMP-nucleon interactions. Optical
readout with CCD cameras allows for the detection for the daily modulation in
the direction of the dark matter wind, while several charge readout channels
allow for the measurement of additional recoil properties. In this article, we
show that the addition of the charge readout analysis to the CCD allows us too
obtain a statistics-limited 90% C.L. upper limit on the rejection factor
of for recoils with energies between 40 and 200
keV. In addition, requiring coincidence between charge signals
and light in the CCD reduces CCD-specific backgrounds by more than two orders
of magnitude.Comment: 8 pages, 6 figures. For proceedings of DPF 2011 conferenc
Radiation Hardness Studies in a CCD with High-Speed Column Parallel Readout
Charge Coupled Devices (CCDs) have been successfully used in several high
energy physics experiments over the past two decades. Their high spatial
resolution and thin sensitive layers make them an excellent tool for studying
short-lived particles. The Linear Collider Flavour Identification (LCFI)
collaboration is developing Column-Parallel CCDs (CPCCDs) for the vertex
detector of the International Linear Collider (ILC). The CPCCDs can be read out
many times faster than standard CCDs, significantly increasing their operating
speed. The results of detailed simulations of the charge transfer inefficiency
(CTI) of a prototype CPCCD are reported and studies of the influence of gate
voltage on the CTI described. The effects of bulk radiation damage on the CTI
of a CPCCD are studied by simulating the effects of two electron trap levels,
0.17 and 0.44 eV, at different concentrations and operating temperatures. The
dependence of the CTI on different occupancy levels (percentage of hit pixels)
and readout frequencies is also studied. The optimal operating temperature for
the CPCCD, where the effects of the charge trapping are at a minimum, is found
to be about 230 K for the range of readout speeds proposed for the ILC. The
results of the full simulation have been compared with a simple analytic model.Comment: 3 pages, 6 figures; presented at IEEE'07, ALCPG'07, ICATPP'0
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