11 research outputs found
β-cyclodextrin-polyurethane polymer: A neutral and eco-friendly heterogeneous catalyst for the one-pot synthesis of 1,4-dihydropyridine and polyhydroquinolien derivatives via Hantzsch reaction under solvent-free conditions
An efficient synthesis of 1,4-dihydropyridine & polyhydroquinolien
derivatives using b-Cyclodextrin-polyurethane polymer (β-CDPU) as a
stationary microvessel and neutral heterogeneous catalyst via a four
component coupling of aldehydes, β-ketoester (2 mol) and ammonium acetate
under solvent-free conditions is described. Compared with the classical
Hantzsch reaction, this new method has the advantages of good yield, short
reaction time and methodological simplicity. β-CDPU was proved to be an
efficient heterogeneous catalyst which could be easily handled and removed
from the reaction mixture by simple filtration, and also recovered and
reused without loss of reactivity