The application of job analysis, the O*NET and competency modelling in New Zealand organisations

The present study aimed to gain an understanding of the extent to which human resource professionals are using and applying job analysis, the Occupational Information Network (O*NET) and competency modelling in New Zealand organisations. This study also explored the research-practice gap in job analysis, as examined through the O*NET and the influence of Taylor and Cable's (2004) article on the O*NET database. An online questionnaire was completed by 107 participants, who were members of the Human Resource Institute of New Zealand research stream. Findings suggest there is high awareness of job analysis, however the application of job analysis in the organisation is commonly hindered by the limited understanding and knowledge amongst human resource professionals. Findings on competency modelling suggest, there has been a possible increase in the application of competency modelling in organisations since Markus, Cooper-Thomas and Allpress (2005) study. The article by Taylor and Cable (2004) has had little influence on the application of the O*NET, suggesting a potential research-practice gap is present in the job analysis area. Specifically, the O*NET database could benefit Human Resource Management (HRM), through supporting the development of job descriptions and person specifications. Human resource professionals could benefit further from extending their awareness of job analysis and competency modelling to the application of these processes in HRM. The need for future research and practical implications for HRM and organisational psychology are discussed

Vitamin D status is heritable and under environment‐dependent selection in the wild

Vitamin D has a well‐established role in skeletal health and is increasingly linked to chronic disease and mortality in humans and companion animals. Despite the clear significance of vitamin D for health and obvious implications for fitness under natural conditions, no longitudinal study has tested whether the circulating concentration of vitamin D is under natural selection in the wild. Here, we show that concentrations of dietary‐derived vitamin D(2) and endogenously produced vitamin D(3) metabolites are heritable and largely polygenic in a wild population of Soay sheep (Ovis aries). Vitamin D(2) status was positively associated with female adult survival, and vitamin D(3) status predicted female fecundity in particular, good environment years when sheep density and competition for resources was low. Our study provides evidence that vitamin D status has the potential to respond to selection, and also provides new insights into how vitamin D metabolism is associated with fitness in the wild

Polymer nano-doplets forming liquid bridges in chemically structured slit pores: A computer simulation

Using a coarse-grained bead-spring model of flexible polymer chains, the structure of a polymeric nanodroplet adsorbed on a chemically decorated flat wall is investigated by means of Molecular Dynamics simulation. We consider sessile drops on a lyophilic (attractive for the monomers) region of circular shape with radius R_D while the remaining part of the substrate is lyophobic. The variation of the droplet shape, including its contact angle, with R_D is studied, and the density profiles across these droplets also are obtained. In addition, the interaction of droplets adsorbed on two walls forming a slit pore with two lyophilic circular regions just opposite of one another is investigated, paying attention to the formation of a liquid bridge between both walls. A central result of our study is the measurement of the force between the two substrate walls at varying wall separation as well as the kinetics of droplet merging. Our results are compared to various phenomenological theories developed for liquid droplets of mesoscopic rather than nanoscopic size.Comment: 8 pages, 9 figures, accepted in J. Chem. Phys. 200

The Grizzly, February 2, 1998

Ursinus to Receive Grant • New Position Causes Concern • Students Remember Joe Hastings • Who\u27s Who at Ursinus • Volkmer Honored • Opinion: American Democracy Under Siege • Jim Fielder\u27s Return Postponed • Ursinus Contributor Dies • Field Hockey Academic All-Americans Honored • Athletic Honor Roll: Asper Pins Down First Player Profile • Bears Fight For Conference Lead • Flying High with Women\u27s Gymnastics • Disgruntled Swimmers Express Concerns About Pool Closinghttps://digitalcommons.ursinus.edu/grizzlynews/1412/thumbnail.jp

Birth weight and stuttering:Evidence from three birth cohorts

Purpose Previous studies have produced conflicting results with regard to the association between birth weight and developmental stuttering. This study sought to determine whether birth weight was associated with childhood and/or adolescent stuttering in three British birth cohort samples. Methods Logistic regression analyses were carried out on data from the Millenium Cohort Study (MCS), British Cohort Study (BCS70) and National Child Development Study (NCDS), whose initial cohorts comprised over 56,000 individuals. The outcome variables were parent-reported stuttering in childhood or in adolescence; the predictors, based on prior research, were birth weight, sex, multiple birth status, vocabulary score and mother's level of education. Birth weight was analysed both as a categorical variable (low birth weight, <2500 g; normal range; high birth weight, ≥ 4000 g) and as a continuous variable. Separate analyses were carried out to determine the impact of birth weight and the other predictors on stuttering during childhood (age 3, 5 and 7 and MCS, BCS70 and NCDS, respectively) or at age 16, when developmental stuttering is likely to be persistent. Results None of the multivariate analyses revealed an association between birth weight and parent-reported stuttering. Sex was a significant predictor of stuttering in all the analyses, with males 1.6 to 3.6 times more likely than females to stutter. Conclusion Our results suggest that birth weight is not a clinically useful predictor of childhood or persistent stuttering

Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male Sex, Mismatch Repair Protein Expression, Lymph Node Positivity, and an ‘Immune Cold’ Phenotype Associated with Poor Survival

Acknowledgments: The authors would like to thank NHS Grampian Biorepository, in particular Joan Wilson, Victoria Morrison, Kristine Nellany, and Nadine Hay, for their assistance in preparing tissue for this project. The authors also thank Tasneem O Atezia and Christina A Christopoulou for their contribution to this project during their time in the McLean laboratory. The laboratory work was instigated when M.H.M., R.J.P. and D.P.B. were based at the Institute of Medical Sciences, University of Aberdeen. Funding This work was funded by project grants from NHS Grampian Endowments and Friends of Anchor (https://www.friendsofanchor.org, charity no. SC025332). Within the McLean laboratory at the University of Aberdeen, SH received a Medical Research Scotland Summer Studentship, and AH received an Aberdeen Summer Research Studentship (University of Aberdeen).Peer reviewedPublisher PD

Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Function and CT Coronary Angiogram (CorCTCA) study

Background: Microvascular and/or vasospastic anginas are relevant causes of ischemia with no obstructive coronary artery disease (INOCA) in patients after computed tomography coronary angiography (CTCA). Objectives: Our research has 2 objectives. The first is to undertake a diagnostic study, and the second is to undertake a nested, clinical trial of stratified medicine. Design: A prospective, multicenter, randomized, blinded, sham-controlled trial of stratified medicine (NCT03477890) will be performed. All-comers referred for clinically indicated CTCA for investigation of suspected coronary artery disease (CAD) will be screened in 3 regional centers. Following informed consent, eligible patients with angina symptoms are enrolled before CTCA and remain eligible if CTCA excludes obstructive CAD. Diagnostic study: Invasive coronary angiography involving an interventional diagnostic procedure (IDP) to assess for disease endotypes: (1) angina due to obstructive CAD (fractional flow reserve ≤0.80); (2) microvascular angina (coronary flow reserve &lt;2.0 and/or index of microvascular resistance &gt;25); (3) microvascular angina due to small vessel spasm (acetylcholine); (4) vasospastic angina due to epicardial coronary spasm (acetylcholine); and (5) noncoronary etiology (normal coronary function). The IDP involves direct invasive measurements using a diagnostic coronary guidewire followed by provocation testing with intracoronary acetylcholine. The primary outcome of the diagnostic study is the reclassification of the initial CTCA diagnosis based on the IDP. Stratified medicine trial: Participants are immediately randomized 1:1 in the catheter laboratory to therapy stratified by endotype (intervention group) or not (control group). The primary outcome of the trial is the mean within-subject change in Seattle Angina Questionnaire score at 6 months. Secondary outcomes include safety, feasibility, diagnostic utility (impact on diagnosis and certainty), and clinical utility (impact on treatment and investigations). Health status assessments include quality of life, illness perception, anxiety-depression score, treatment satisfaction, and physical activity. Participants who are not randomized will enter a follow-up registry. Health and economic outcomes in the longer term will be assessed using electronic patient record linkage. Value: CorCTCA will prospectively characterize the prevalence of disease endotypes in INOCA and determine the clinical value of stratified medicine in this population

Vitamin D status in cats with feline immunodeficiency virus

Feline immunodeficiency virus (FIV) is a lentivirus that can lead to a syndrome of acquired immune dysfunction. Infected cats often remain asymptomatic for several years before immune dysfunction leads to an increased risk for the development of systemic diseases, neoplasia and opportunistic infections. FIV is structurally related to human immunodeficiency virus (HIV) and the pathogenesis of FIV‐related disease is similar to that seen in HIV‐infected patients. Observational studies have documented an association between low plasma vitamin D and HIV infection. Vitamin D status has been shown to be associated with HIV‐related disease progression, morbidity and mortality. The objective of this study was to examine the hypothesis that vitamin D status, as assessed by serum 25‐hydroxyvitamin D [25(OH)D] concentrations, are lower in cats with FIV infection compared to healthy control cats. Serum 25(OH)D concentrations were measured in 20 healthy cats, 39 hospitalized ill cats and 59 cats infected with FIV. Cats which were FIV infected had significantly lower 25(OH)D concentrations compared to healthy control cats. Serum 25(OH)D concentrations were not significantly different between FIV‐infected cats and hospitalized ill cats. Further investigations are warranted to determine whether vitamin D status influences the prognosis of cats infected with FIV