Maude Adams

Maude Adams was a hugely successful American stage actress of the late nineteenth and early twentieth centuries. She was perhaps most famous for her performance as Peter Pan. Whilst she never appeared on screen she nevertheless made a significant contribution to the film industry through research she coordinated into lighting technology and color cinematography during the 1920s. Notoriously private, Adams gave few interviews and few personal papers survive. As a result her own thoughts on her work remain elusive and for the most part this research has relied on film trade journals, newspaper reports, and previous biographies

cDNA cloning of MCT1, a monocarboxylate transporter from rat skeletal muscle

AbstractPCR was used to amplify the coding region of CHO MCT1 cDNA. This was then used to screen a rat skeletal muscle cDNA library which lead to the isolation of a full length cDNA encoding MCT1 from rat. The cDNA derived amino acid sequence shows 94% and 86% identity to CHO and human MCT1, respectively

Psychosocial predictors of postnatal anxiety and depression: Using Structural Equation Modelling to investigate the relationship between pressure to breastfeed, healthcare professional support, postnatal guilt and shame, and postnatal anxiety and depression within an infant feeding context

In high income settings, high perceived pressure to breastfeed and poor perceived quality of healthcare professional support have been associated with early breastfeeding cessation, guilt, and shame. This is important because guilt and shame significantly predict postnatal anxiety and depression. No previous attempts have been made to provide quantitative evidence for relationships mapped between the postnatal social context, infant feeding method, and emotional wellbeing outcomes. The current study aimed to empirically investigate aforementioned pathways. Structural equation modelling was applied to survey data provided online by 876 mothers. Guilt and shame both significantly predicted anxiety and depression. Poor healthcare professional support and high pressure to breastfeed increased anxiety and depression, and these effects were explained by indirect pathways through increases in guilt and shame. Formula feeding exclusivity was negatively correlated with postnatal anxiety symptoms. This finding may be explained by feelings of relief associated with observed infant weight gain and being able to share infant feeding responsibilities with others e.g., one’s partner. This relationship, however, was counterbalanced by an indirect pathway where greater formula feeding exclusivity positively predicted guilt, which in turn increased postnatal anxiety score. While guilt acted as mediator of infant feeding method to increase postnatal depression and anxiety, shame acted independently of infant feeding method. These identified differences provide empirical support for the transferability of general definitions of guilt (i.e., as remorse for having committed a moral transgression) and shame (i.e., internalisation of transgressive remorse to the self), to an infant feeding context. Recommendations for healthcare practitioners and the maternal social support network are discussed

Exploring fraity and sarcopenia in older adults admitted to acute medical unit, looking at prevalence, trajectory, and outcomes:A protocol testing the feasibility and acceptability of the TYSON study

BackgroundFrailty and sarcopenia are common in older people and are associated with adverse outcomes including increased mortality and morbidity. It is unclear whether screening for frailty and sarcopenia would identify specific populations most at risk of poor outcomes during unplanned hospital admissions, which screening tools should be used and what the trajectory of both conditions are over the course of an admission. The TYSON study is an observational cohort study aiming to determine the prevalence, trajectory and outcomes associated with frailty and sarcopenia in different patient cohorts. This protocol tests the feasibility and acceptability of TYSON processes.ObjectivesTo determine in acutely admitted medical patients who are older adults: Primary: The feasibility and acceptability of frailty and sarcopenia assessments; Secondary: (1) Differences in community and hospital frailty assessments, as assessed by the medical team, the patient and elderly care physicians, (2) The dynamic changes in frailty and sarcopenia during a hospital admission, and patient outcomes; Exploratory: Inflammatory and metabolic mediators associated with frailty and sarcopenia.MethodsA single centre, prospective observational study including patients aged ≥ 65 years admitted to an acute medical unit. Frailty assessments include the Rockwood clinical frailty and e-frailty index. Sarcopenia assessments include the Bilateral Anterior Thigh Thickness (BATT) measurement. Each participant will be asked to complete 5 visits, at day 0, day 3, day 7, month 3 and month 6. Blood samples will be collected to explore inflammatory and metabolic markers associated with frailty and sarcopenia. The study and protocol have been ethically approved by the Health Research Authority (REC 20/WA/0263).DiscussionThe study will determine the feasibility and acceptability of frailty and sarcopenia assessments in an acute hospital setting, and inform on the prevalence, trajectory and associated outcomes of frailty and sarcopenia in this group of patients. An inflammatory and metabolic profile will be explored in frailty and sarcopenia

Modern slavery, environmental degradation and climate change: present and future pathways for addressing the nexus

Roundtable Report based on the findings of an event hosted by the Rights Lab, Delta 8.7 and funded by WWF U.S. to support the development of a collaborative action plan to support efforts for the antislavery and environmental communities to work together to tackle the modern slavery-environmental degradation-climate change nexus

High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation

Leaf senescence is an essential developmental process that impacts dramatically on crop yields and involves altered regulation of thousands of genes and many metabolic and signaling pathways, resulting in major changes in the leaf. The regulation of senescence is complex, and although senescence regulatory genes have been characterized, there is little information on how these function in the global control of the process. We used microarray analysis to obtain a highresolution time-course profile of gene expression during development of a single leaf over a 3-week period to senescence. A complex experimental design approach and a combination of methods were used to extract high-quality replicated data and to identify differentially expressed genes. The multiple time points enable the use of highly informative clustering to reveal distinct time points at which signaling and metabolic pathways change. Analysis of motif enrichment, as well as comparison of transcription factor (TF) families showing altered expression over the time course, identify clear groups of TFs active at different stages of leaf development and senescence. These data enable connection of metabolic processes, signaling pathways, and specific TF activity, which will underpin the development of network models to elucidate the process of senescence

Resilience and post‐traumatic growth in the transition to motherhood during the COVID ‐19 pandemic: A qualitative exploratory study

Most perinatal research relating to COVID‐19 focuses on its negative impact on maternal and parental mental health. Currently, there are limited data on how to optimise positive health during the pandemic. We aimed to bridge this knowledge gap by exploring how women have adapted to becoming a new parent during the pandemic and to identify elements of resilience and growth within their narratives. Mothers of infants under the age of 4 months were recruited as part of a wider UK mixed‐methods study. Semi‐structured interviews with 20 mothers elicited data about how COVID‐19 had influenced their transition to parent a new infant, and if and how they adapted during the pandemic, what strategies they used, and if and how these had been effective. Directed qualitative content analysis was undertaken, and pre‐existing theoretical frameworks of resilience and post‐traumatic growth (PTG) were used to analyse and interpret the data set. The findings show evidence of a range of resilience and PTG concepts experienced during the pandemic in this cohort. Salient resilience themes included personal (active coping, reflective functioning, and meaning‐making), relational (social support, partner relationships, and family relationships), and contextual (health and social connectedness) factors. There was also evidence of PTG in terms of the potential for new work‐related and leisure opportunities, and women developing wider and more meaningful connections with others. Although further research is needed, and with individuals from diverse socioeconomic backgrounds, these findings emphasise the significance of social support and connectivity as vital to positive mental health. Opportunities to increase digital innovations to connect and support new parents should be maximised to buffer the negative impacts of further social distancing and crisis situations

Ecological interactions between Antarctic krill (Euphausia superba) and baleen whales in the South Sandwich Islands region – Exploring predator-prey biomass ratios

Following the cessation of whaling, the southwest Atlantic humpback whale (Megaptera novaeangliae) population is thought to be close to pre-exploitation size, reversing 20th century changes in abundance. Using a model-based approach applied to concurrently collected data on baleen whale abundance and Antarctic krill (Euphausia superba) biomass in the South Sandwich Islands (SSI) region, we explore ecological interactions between these taxa. Krill biomass and baleen whale density were highest to the north and northeast of the SSI, where the Antarctic Circumpolar Current (ACC) is deflected around the island chain. Humpback whale density was elevated at locations of krill biomass density >150 gm-2. Krill consumption by baleen whales was estimated at 19–29% of the available krill standing stock. We used historic whaling data to confirm the plausibility of these consumption rates and found evidence of rapid weight gain in humpback whales, such that blubber depleted during the breeding season could be restored in a much shorter period than previously assumed. Little is known about krill replenishment rates in the flow of the ACC, or about niche separation between recovering baleen whale populations; both factors may affect species carrying capacities and further monitoring will be required to inform the management of human activities in the region

2002 AAPP Monograph Series: African American Professors Program

The African American Professors Program (AAPP) at the University of South Carolina is pleased to produce the second edition of its annual monograph series. It is fitting that the program contrives to assume a leadership role in promoting scholarly products that prove to be useful in research endeavors by faculty and students in higher education. Scholars who have contributed manuscripts for this monograph are to be commended for adding this additional responsibility to their academic workload. Writing across disciplines adds to the intellectual diversity of these papers. From neophytes, relatively speaking, to an array of very experienced individuals, the chapters have been researched and comprehensively written. Founded in 1997 through the Department of Educational Leadership and Policies in the College of Education, AAPP was designed to address the underrepresentation of African American professors on college and university campuses. Its mission is to expand the pool of these professors in critical academic and research areas. Sponsored by the University of South Carolina, the W.K. Kellogg Foundation, and the South Carolina General Assembly, the program recruits students with bachelor\u27s, master\u27s, and doctoral degrees for disciplines in which African Americans, currently, are underrepresented. An important component of the program is the mentoring experience that is provided. Each student is assigned to a mentor professor who guides the student through a selected academic program and provides various learning experiences. When possible, the mentor serves as chair of the student\u27s doctoral committee. The mentor, also, provides opportunities for the student to team teach, conduct research, and co-author publications. Students have opportunities to attend committee, faculty, and professional meetings, as well as to engage in a range of activities that characterize professional life in academia. Scholars enrolled in the program also are involved in programmatic and institutional workshops, independent research, and program development. The continuation of this monograph series is seen as responding to an opportunity to be sensitive to an academic expectation of graduates as they pursue career placement and, also, one that allows for the dissemination of AAPP products to a broader community. We hope that you will read this monograph of the African American Professors Program with enthusiasm or enlightenment. John McFadden, Ph.D. The Benjamin Elijah Mays Professor Director, African American Professors Program University of South Carolinahttps://scholarcommons.sc.edu/mcfadden_monographs/1000/thumbnail.jp