Differentiated Induction: An Enhanced Model for the New Teacher Induction Program

The Ontario Ministry of Education established the New Teacher Induction Program (NTIP) in 2006 to facilitate a smoother transition into the teaching profession for beginning teachers. This program intends to provide another full year of training and support to beginning teachers. The components of NTIP are: (a) a system orientation; (b) peer mentorship; and (c) targeted professional learning opportunities. Through the provision of differentiated professional learning communities and enhanced mentoring opportunities, this Organizational Improvement Plan (OIP) revises the existing induction structure in the Tungsten Board of Education. Using an adaptive, situational leadership style, the NTIP Facilitator employs the Awareness, Desire, Knowledge, Ability, and Reinforcement(ADKAR)model and the Care, Relate, Examine, Acquire, Try, Expand and Renew(CREATER)change management models to guide the change process. The change implementation plan and communication plan both leverage existing teacher leaders to facilitate the professional learning communities and provides individualized follow-up supports through in-class instructional coaching opportunities. The Plan-Do-Study-Act (PDSA)model monitors and evaluates progress. Enhanced opportunities for professional capacity building supports the implementation of instructional practices, improvements to teacher self-efficacy, reduces attrition rates, and improves outcomes for learners

Dietetic Students’ Changes in Attitudes after Participating in Online Interprofessional Education

Interprofessional education (IPE) is an accreditation requirement and an important component of training for future registered dietitian nutritionists (RDNs) and access to quality IPE is often limited in online programs. An online IPE module was developed to provide dietetics students the opportunity to build collaborative skills with students in other healthcare training programs. A research study was designed to answer the following research question: How and to what extent does participation in an online IPE module impact online dietetics students’ attitudes of interprofessional practice? Participants were dietetics students enrolled in an upper-division online dietetics course. Data gathered included a retrospective pre-post survey, reflection journal entries, and focus group interviews. Results suggested that the online IPE intervention had a positive impact on dietetics students’ attitudes of interprofessional practice and enhanced their understanding of the roles of members of the interprofessional team. The opportunity for participants to work on a final project as part of an interprofessional team likely contributed to the positive shared learning experiences and overall growth in interprofessional collaboration

Landscape and Garden Plants Sample Submission to the Plant and Pest Diagnostic Clinic

Diagnoses are made easier and turnaround time is improved when the quality of plant samples is maintained. This NebGuide discusses the proper guidelines for submitting landscape and garden plants, turf, and tree samples to UNL’s Plant and Pest Diagnostic Clinic. There are several important things to consider when collecting, packaging, and sending plant or insect samples for diagnosis in a plant diagnostic laboratory. Collect an adequate amount of plant material. When feasible, the sample should include the entire plant — roots, stems, leaves, flowers, and fruits. Whole plants are needed to properly evaluate the sample. If the whole plant is not available, photos of the symptomatic plants can improve accuracy of diagnosis

Psychobiological Models of Adolescent Risk: Implications for Prevention and Intervention

Psychobiological models of risk have much to contribute to the prevention of and intervention with risky behavior among adolescents. Emerging research is beginning to provide better information about mechanisms underlying individual differences in risky behavior (e.g., differences in self-regulation) and providing insight into unique vulnerabilities that occur during adolescence (e.g., increases in reward seeking). This work suggests ways in which prevention programming can be designed to be sensitive to both individual differences and developmental timing. Psychobiological models of risk also have practical implications for the manner and methods of conducting prevention and intervention work. Future work in both the etiology and prevention of risky behavior can benefit from ongoing dialogue and has the potential to result in a more sophisticated understanding of the mechanisms of change related to risky behavior

Imbalance in the response of pre- and post-synaptic components to amyloidopathy

Alzheimer’s disease (AD)-associated synaptic dysfunction drives the progression of pathology from its earliest stages. Aβ species, both soluble and in plaque deposits, have been causally related to the progressive, structural and functional impairments observed in AD. It is, however, still unclear how Aβ plaques develop over time and how they progressively affect local synapse density and turnover. Here we observed, in a mouse model of AD, that Aβ plaques grow faster in the earlier stages of the disease and if their initial area is > 500 µm2; this may be due to deposition occurring in the cloud part of the plaque. In addition, synaptic turnover is higher in the presence of amyloid pathology and this is paralleled by a reduction in pre- but not post-synaptic densities. Plaque proximity does not appear to have an impact on synaptic dynamics. These observations indicate an imbalance in the response of the pre- and post-synaptic terminals and that therapeutics, alongside targeting the underlying pathology, need to address changes in synapse dynamics

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Emergency and urgent care systems in Australia, Denmark, England, France, Germany and the Netherlands - Analyzing organization, payment and reforms.

INTRODUCTION: Increasing numbers of hospital emergency department (ED) visits pose a challenge to health systems in many countries. This paper aims to examine emergency and urgent care systems, in six countries and to identify reform trends in response to current challenges. METHODS: Based on a literature review, six countries - Australia, Denmark, England, France, Germany and the Netherlands - were selected for analysis. Information was collected using a standardized questionnaire that was completed by national experts. These experts reviewed relevant policy documents and provided information on (1) the organization and planning of emergency and urgent care, (2) payment systems for EDs and urgent primary care providers, and (3) reform initiatives. RESULTS: In the six countries four main reform approaches could be identified: (a) extending the availability of urgent primary care, (b) concentrating and centralizing the provision of urgent primary care, (c) improving coordination between urgent primary care and emergency care, and (d) concentrating emergency care provision at fewer institutions. The design of payment systems for urgent primary care and for emergency care is often aligned to support these reforms. CONCLUSION: Better guidance of patients and a reconfiguration of emergency and urgent care are the most important measures taken to address the current challenges. Nationwide planning of all emergency care providers, closely coordinated reforms and informing patients can support future reforms

The Grizzly, November 19, 1990

Frat Pledges\u27 Academics • Where Does Your Student Activity Fee Go? • Foreign Policy and the Press • Thanksgiving Food Drive • Date Rape Discussed • New Food Plans Developed • Campus Jobs = Easy $$$ • The Musser Experience • A Legend Lives On • Economics Conference Returns • Language Labs: Olin Addition • Television: Whose Reality is it Anyway? • Berman Art • Ursinus Band • Men\u27s Basketball Plays in Scranton Tournament • Gymnasts Prepare for Season • MAC Academic Honor Roll • Swimmers Waste Time at Kings Meet • Ski Club Plans Trip • All-Star Baseball Clinic to be Held at UC • Letters: Is the Grizzly Still a Newspaper?; Support our Positive Efforts; Bring Back our Salt • A Meal Choice? • Slinging Mud to Win • What was the Question? • A New Dimension to Medicinehttps://digitalcommons.ursinus.edu/grizzlynews/1265/thumbnail.jp

Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial

Background: Rucaparib, a poly(ADP-ribose) polymerase inhibitor, has anticancer activity in recurrent ovarian carcinoma harbouring a BRCA mutation or high percentage of genome-wide loss of heterozygosity. In this trial we assessed rucaparib versus placebo after response to second-line or later platinum-based chemotherapy in patients with high-grade, recurrent, platinum-sensitive ovarian carcinoma. Methods: In this randomised, double-blind, placebo-controlled, phase 3 trial, we recruited patients from 87 hospitals and cancer centres across 11 countries. Eligible patients were aged 18 years or older, had a platinum-sensitive, high-grade serous or endometrioid ovarian, primary peritoneal, or fallopian tube carcinoma, had received at least two previous platinum-based chemotherapy regimens, had achieved complete or partial response to their last platinum-based regimen, had a cancer antigen 125 concentration of less than the upper limit of normal, had a performance status of 0–1, and had adequate organ function. Patients were ineligible if they had symptomatic or untreated central nervous system metastases, had received anticancer therapy 14 days or fewer before starting the study, or had received previous treatment with a poly(ADP-ribose) polymerase inhibitor. We randomly allocated patients 2:1 to receive oral rucaparib 600 mg twice daily or placebo in 28 day cycles using a computer-generated sequence (block size of six, stratified by homologous recombination repair gene mutation status, progression-free interval after the penultimate platinum-based regimen, and best response to the most recent platinum-based regimen). Patients, investigators, site staff, assessors, and the funder were masked to assignments. The primary outcome was investigator-assessed progression-free survival evaluated with use of an ordered step-down procedure for three nested cohorts: patients with BRCA mutations (carcinoma associated with deleterious germline or somatic BRCA mutations), patients with homologous recombination deficiencies (BRCA mutant or BRCA wild-type and high loss of heterozygosity), and the intention-to-treat population, assessed at screening and every 12 weeks thereafter. This trial is registered with ClinicalTrials.gov, number NCT01968213; enrolment is complete. Findings: Between April 7, 2014, and July 19, 2016, we randomly allocated 564 patients: 375 (66%) to rucaparib and 189 (34%) to placebo. Median progression-free survival in patients with a BRCA-mutant carcinoma was 16·6 months (95% CI 13·4–22·9; 130 [35%] patients) in the rucaparib group versus 5·4 months (3·4–6·7; 66 [35%] patients) in the placebo group (hazard ratio 0·23 [95% CI 0·16–0·34]; p<0·0001). In patients with a homologous recombination deficient carcinoma (236 [63%] vs 118 [62%]), it was 13·6 months (10·9–16·2) versus 5·4 months (5·1–5·6; 0·32 [0·24–0·42]; p<0·0001). In the intention-to-treat population, it was 10·8 months (8·3–11·4) versus 5·4 months (5·3–5·5; 0·36 [0·30–0·45]; p<0·0001). Treatment-emergent adverse events of grade 3 or higher in the safety population (372 [99%] patients in the rucaparib group vs 189 [100%] in the placebo group) were reported in 209 (56%) patients in the rucaparib group versus 28 (15%) in the placebo group, the most common of which were anaemia or decreased haemoglobin concentration (70 [19%] vs one [1%]) and increased alanine or aspartate aminotransferase concentration (39 [10%] vs none). Interpretation: Across all primary analysis groups, rucaparib significantly improved progression-free survival in patients with platinum-sensitive ovarian cancer who had achieved a response to platinum-based chemotherapy. ARIEL3 provides further evidence that use of a poly(ADP-ribose) polymerase inhibitor in the maintenance treatment setting versus placebo could be considered a new standard of care for women with platinum-sensitive ovarian cancer following a complete or partial response to second-line or later platinum-based chemotherapy. Funding: Clovis Oncology