488 research outputs found

    Voltaiq data format—A standard data format for collection of battery data to enable big data comparisons and analyses across the battery lifecycle

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    Batteries have enabled modernization of society through portability of electricity. Batteries are also a crucial component to enabling clean technologies of the future such as grid storage and electrified transportation. Because of their ubiquity in modern society, global organizations develop and commercialize batteries for their electrified products. Across the field of battery development, in both commercial and academic settings, there is broad utility in standardization of data formats amongst disparate data sources, labs, equipment, organizations, industries, and lifecycle phases. Due to the way the nascent industry developed, there is a lack of standardization for how performance data is recorded, which is now hindering the industry’s ability to learn from data and accelerate growth. Herein, we describe the different types of data, formats, conventions, and standardization for each phase in the battery lifecycle. Next, we provide a standard data format and conventions for the community to either utilize in their data collection practices or map their existing data into: the Voltaiq Data Format (VDF). This standard data format provides the flexibility needed to capture the variability in data formats and conventions along the battery lifecycle. The utility of this standard format aids in collaboration within and across organizations, accelerating innovation across the industry, and paves the way for the battery community to start utilizing the power of machine learning and data science

    A comprehensive assessment of environmental exposures among 1000 North American patients with primary sclerosing cholangitis, with and without inflammatory bowel disease

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    BACKGROUND: The relationships between primary sclerosing cholangitis (PSC) and the environment are largely unknown. AIM: To validate associations reported in previous studies and to identify novel environmental exposures among PSC patients. METHODS: We performed a multicenter, case-control analysis utilising self-administered questionnaires. Responses between cases (n = 1000) and controls (n = 663) were compared using multivariable logistic regression adjusted for age and gender. The model was further stratified based on inflammatory bowel disease (IBD) status (with IBD n = 741 without IBD n = 259). RESULTS: Smoking was associated with PSC only when IBD was present (OR, 0.5; 95% CI 0.4-0.7) but not among those PSC patients without IBD (OR, 0.9; 95% CI 0.7-1.2). Compared to controls, women with PSC (irrespective of the presence of IBD) were less likely to have received hormone replacement therapy (HRT; OR, 0.5; 95% CI 0.4-0.7) and were more likely to have recurrent urinary tract infections (OR, 1.6; 95% CI 1.2-2.3). PSC patients regardless of gender or IBD status were less likely to eat fish (OR, 0.4; 95% CI 0.3-0.6) and grilled/barbecued meat (OR, 0.8; 95% CI 0.7-0.9). In contrast, PSC patients with and without IBD were more likely to consume steak/burgers that were more well done (OR, 1.3; 95% CI 1.2-1.5). CONCLUSIONS: IBD (rather than PSC) is associated with smoking. Women with PSC are more likely to have recurrent urinary tract infections and less likely to receive HRT. Dietary intake and methods of food preparation differ in PSC patients when compared to controls

    Systematic Identification of Cellular Signals Reactivating Kaposi Sarcoma–Associated Herpesvirus

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    The herpesvirus life cycle has two distinct phases: latency and lytic replication. The balance between these two phases is critical for viral pathogenesis. It is believed that cellular signals regulate the switch from latency to lytic replication. To systematically evaluate the cellular signals regulating this reactivation process in Kaposi sarcoma–associated herpesvirus, the effects of 26,000 full-length cDNA expression constructs on viral reactivation were individually assessed in primary effusion lymphoma–derived cells that harbor the latent virus. A group of diverse cellular signaling proteins were identified and validated in their effect of inducing viral lytic gene expression from the latent viral genome. The results suggest that multiple cellular signaling pathways can reactivate the virus in a genetically homogeneous cell population. Further analysis revealed that the Raf/MEK/ERK/Ets-1 pathway mediates Ras-induced reactivation. The same pathway also mediates spontaneous reactivation, which sets the first example to our knowledge of a specific cellular pathway being studied in the spontaneous reactivation process. Our study provides a functional genomic approach to systematically identify the cellular signals regulating the herpesvirus life cycle, thus facilitating better understanding of a fundamental issue in virology and identifying novel therapeutic targets

    Innovation for an inclusive future

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    This workshop will focus on setting the agenda for research, practice and policy in support of inclusive design for third generation computer-based products. The next generation of technology represents an unprecedented opportunity to improve the quality of life for groups of users who have previously faced exclusion, such as those with impairments and older citizens. At the same time it risks creating a greater digital divide and further exclusion. How we approach design for this new generation will determine whether or not the third wave will provide positive advances towards an inclusive digital world. We therefore need to put forward both a rationale for inclusive design and provide pointers towards technical development and design practice in support of inclusion. It is our belief that there is not only a strong moral case for design for inclusion but also significant commercial incentive, which may be key to persuading influential players to focus on inclusion. Therefore one of our key objectives is to describe and promote the advantages of designing ‘in from the edges’ of the user population rather than designing for a notional ‘average’ user

    Firm preparation for ISO 9001 certification: the case of the hotel industry in Portugal

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    The purpose of this study is to assess whether companies conduct preparations, such as managing culture, before starting to implement an ISO 9001 Quality Management System (QMS). Based on a literature review, the paper develops a model of firm preparation for ISO 9001 certification and several research hypotheses. The survey research method adopted consists of data collection through questionnaires – sent to hotels of four and five stars, in Portugal, in two different moments (2012 and 2014) – and of a longitudinal data analysis based on non-parametric statistical tests. Results show that the majority of companies conduct preparations before starting to implement an ISO 9001 QMS. However, most companies do not assess their initial situation, nor do they plan for the preparations. One of the significant implications from this research is that a more coherent and integrated approach in ISO 9001 preparation is required. Other implications for practice and for research are also noted. This is the first study, as far as the authors are aware of, that addresses the topic of planning for the preparations that a company can make before starting to implement an ISO 9001 QMS.Fundação para a Ciência e a Tecnologia (grant UID/ECO/04007/2013) e FEDER/COMPETE (POCI-01-0145- FEDER-007659)info:eu-repo/semantics/publishedVersio

    Examining the quality and management of non-geometric building information modelling data at project hand-over

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    Through the exponential global increase of Building Information Modelling (BIM) adoption across the Construction industry, and the emergence of inter-connected, strategic and data-rich solutions; such as Big Data, the Internet of Things and Smart Cities, the importance associated with activities and decisions reliant on exact data input, transaction, analysis, and resulting actions becomes exponentially magnified. The supply of inaccurate BIM data may negatively impact on systems and processes that require fully assured data of appropriate quality/veracity, to support informed decision making, deliver functionality, facilitate services, or direct strategic actions within the built environment. This preliminary research intends to provide a catalyst for discussion, analysis and information retrieval relating to Building Information Modelling (BIM) processes where non-geometric data errors may; or are predicted to occur within a project environment. This may result in the delivery of data that cannot be described as representing truth or of good quality, and therefore of little value or use to the data user. The wider aspects of this research investigates specifically non-geometric data veracity & associated dimensions of data quality; in order to discover and explore future solutions to resolve current industry data quality assessment challenges. This paper provides feedback from the research focusing on the current state, presenting existing industry challenges and proposes further research areas based on initial findings

    Upotreba živinih mjernih uređaja u zdravstvenim ustanovama u Hrvatskoj

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    In 2009, we conducted a survey to assess the use of mercury-based thermometers and sphygmomanometers and their disposal in Croatian healthcare facilities. The questionnaire addressing the use of mercury-based medical devices, waste management, preferences between mercury-based and electronic devices, and the knowledge on mercury toxicity was filled by ward nurses affiliated with 40 (71.4 %) out of 56 contacted healthcare facilities. Only one of these facilities had given up the use of mercury-containing medical devices at the time. As many as 84.6 % of the nurses believed that broken devices did not increase the risk of mercury exposure, even though 90 % claimed they were aware of mercury toxicity. In fact, 69.4 % of the nurses preferred mercury-containing devices on account of their precision and reliability and because they received little training in the use of electronic devices. Breaking of thermometers and sphygmomanometers is common in healthcare facilities. The number of broken thermometers and sphygmomanometers was estimated to 278 and fi ve per month, respectively. Only 18 (46.2 %) of the surveyed healthcare facilities claimed to have had a proper disposal procedure for mercury from broken devices. Nurses, who most often handle these devices and collect mercury spills, are primarily exposed to mercury vapours via inhalation. Croatia has adopted the EU Directive 76/769/EEC intended to reduce mercury exposure in the living and working environment. Our survey suggests that all healthcare professionals need training in proper management of broken mercury-based medical devices, nurses in particular. To reduce the risk of exposure, all Croatian healthcare facilities should implement guidelines for staff protection and programmes to gradually replace mercury-based with electronic devices.Živa je štetni čimbenik izravno povezan s provođenjem zdravstvene zaštite. Tijekom 2009. provedeno je istraživanje u zdravstvenim ustanovama RH, s ciljem procjene uporabe živinih mjernih instrumenata, toplomjera i tlakomjera te načina odlaganja razbijenih uređaja. Upitnik o uporabi živinih uređaja, zbrinjavanju otpada, sklonostima uporabi živinih, odnosno elektroničkih mjernih uređaja te pitanja o poznavanju toksičnosti žive, ispunile su odjelne medicinske sestre iz 40 (71,4 %) od 56 zdravstvenih ustanova. Samo u jednoj ustanovi živini se mjerni uređaji uopće ne rabe. Čak 84,6 % ispitanica smatra da nisu dodatno izložene živi iz razbijenih uređaja, iako je 90 % svjesno toksičnosti Hg. Zbog njihove preciznosti, pouzdanosti i nedostatka edukacije o uporabi i održavanju elektroničkih uređaja prednost uporabi živinih uređaja daje 69,4 % medicinskih sestara. Razbijanje toplomjera i tlakomjera čest je incident u zdravstvenim ustanovama. Procijenjeni broj mjesečno razbijenih toplomjera bio je do 278, a razbijenih tlakomjera do 5. U samo 18 (46,2 %) ustanova pravilno se odlagala živa iz razbijenih uređaja. Medicinske sestre koje najčešće rukuju uređajima i prikupljaju živu najizloženije su živinim parama putem inhalacije. U Hrvatskoj su doneseni pravni akti s namjerom smanjenja prisutnosti žive u životnom i radnom okolišu. Time je stupila na snagu EU direktiva 76/769/EEZ-a o smanjenju proizvodnje i prometa uređaja koji ju sadržavaju. Rezultati upućuju na potrebu edukacije svih zdravstvenih radnika, posebno medicinskih sestara, o zbrinjavanju razbijenih živinih mjernih uređaja. Radi smanjenja potencijalne izloženosti i osiguranja boljih zdravstvenih uvjeta na radnome mjestu sve hrvatske zdravstvene ustanove trebaju provoditi smjernice za zaštitu radnika i programe za smanjenje uporabe žive uporabom zamjenskih toplomjera i tlakomjera dostupnih na tržištu
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