Corporate governance and corporate social responsibility reporting: a case study of Malaysia

Corporate social responsibility (CSR) is relatively a new concept to developing countries, hence it is less prevalent as compared to developed countries. There is growing consensus that CSR is highly contextual. The literature indicates that the concept and practices of CSR vary depending on the country, region, culture, management perspectives, and geographical and business systems. Accordingly, it can be concluded that existing CSR in developed countries cannot be employed in developing countries. The need for companies to be positively perceived by their stakeholders and to stay competitive has led to the necessity of companies to communicate their social responsibility initiatives. Loss of social confidence due to crises has also prompted companies to report on their CSR activities to enable consumers and investors to make informed choices and rational investment decisions. Various efforts have been undertaken to encourage companies to report on CSR activities. Nevertheless, the practise of CSR reporting in developing countries remains in embryonic form. Researchers propose corporate governance good practice should promote ethics, fairness, transparency and accountability which form the foundation of CSR practices. Given the increasing importance attached to both corporate governance and CSR, this study primary objective is to investigate the effects of corporate governance practices on the extent of CSR reporting in Malaysia. Hypotheses are developed by reference to several theoretical constructs namely agency, resource dependence, neo-institutional sociology and stakeholder-agency theories. This study employs content analysis to examine the annual reports of 450 non-financial companies listed on Bursa Malaysia over the years 2008-2013. A self-constructed CSR checklist consisting of 51 CSR-related items categorised under six themes was used to measure the extent of CSR reporting in the annual reports. To determine the influence of corporate governance on CSR reporting, multiple regression analysis was utilised. The results show that over time, companies are increasingly disclosing more information on CSR, suggesting that this area is increasingly gaining the attention of companies. The effective role played by government and regulators is seen as the likely reason for the increasing reporting trend. Theme wise, most companies are inclined towards reporting human resource information; demonstrating that satisfying the needs of their workers is central to their success. Although on the whole the reported levels in Malaysia fall short of disclosure in developed countries and also several countries in the same region, the increasing trend appears promising. Given more time, CSR reporting levels may approach those reported in developed countries. This study also looks at the influence of ownership structure and board of directors attributes on the level of CSR reporting in Malaysia. Specifically, it attempts to examine the effect of ownership by directors and institutions, board independence, board meeting frequency, board diversity and CEO duality on CSR reporting. Nevertheless, despite continuous government efforts to improve the practise of corporate governance among companies, this study failed to find any significant impact of board meeting frequency, board diversity and CEO duality on CSR reporting level. Meanwhile, the association between board independence and directors who are finance experts and CSR reporting are found to be industry-specific, suggestive that the environments in certain industries deter the board from increasing CSR. Interestingly, this study exhibits significant results for both ownership by directors and institutions. Shareholdings by directors prove to have negative bearing on CSR reporting due to the entrenchment effect. Institutional ownership while demonstrating a significant result, contributes to a lower reporting of CSR information. On the whole, the results imply that the prevalent dominant family ownership of companies in Malaysia is an impediment to the effective practise of CSR. This study is significant because it is one of the first to provide empirical evidence on the effect of corporate governance mechanisms on CSR reporting in a developing country. This study provides feedback to regulators and policymakers on the effectiveness of their efforts in promoting accountability and transparency through increased CSR reporting. In addition, it also offers an overview of the effectiveness of corporate governance practices in Malaysia which should enable regulators to improve the system of corporate governance especially increasing CSR practices

Rabies Vaccination and Immune Status of Owned Dogs in Zaria, Nigeria

Nigerian Veterinary Journal, Vol. 32(3): 2011; 204 - 20

Phytochemical Screening and Hepatoprotective Effect of Alhagi maurorum Boiss (Leguminosae) Against Paracetamol-Induced Hepatotoxicity in Rabbits

Purpose: To evaluate the hepatoprotective activity of aqueous-ethanol (30:70 %) extract of Alhagi maurorum Boiss. (Leguminosae) whole plant against paracetamol-induced liver injury in experimental rabbits.Methods: Aqueous-ethanol extract of Alhagi maurorum at doses of 250 mg/kg and 500 mg/kg body weight, p.o., was administered for 7 days in paracetamol (2 gm/kg, s.c.) intoxicated rabbits and compared with silymarine (50 mg/kg, p.o.)-treated rabbits. Biochemical parameters, alkaline phosphatase (ALP), serum glutamic oxalacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and total bilirubin (TB) levels were recorded to investigate the degree of improvement in the conditions of the rabbits. The liver was removed, washed with normal saline and preserved in 10 % formalin and used in histopathological studies of hepatic architecture by microscopy. Phytochemical screening of the extract was also carried out.Results: The levels of biochemical parameters were increased in paracetamol intoxicated rabbits when compared with the normal group. The extract, at doses of 250 and 500 mg/kg, exhibited significant (p < 0.001) reduction in biochemical parameters (ALP, SGOT, SGPT and TB). Hepatoprotective activity was also confirmed by histopathological findings. Furthermore, the phytochemical profile of the extract revealed the presence of tannins, alkaloids, saponins and flavonoids.Conclusion: These results suggest that Alhagi maurorum extract possesses significant hepatoprotective effect against paracetamol-induced hepatotoxicity and this may be due to the presence of flavonoids and tannins.Keywords: Alhagi maurorum, Hepatoprotective, Paracetamol, Silymarin, Histopatholog

Molecular epidemiology of group A human rotaviruses in North West region, Cameroon

Background: Rotavirus (RV) is the most common cause of severe diarrhea in children <5 years of age worldwide accounting for 527,000 deathsannually. Over 80% of these deaths occur in South Asia and sub-Saharan Africa. RV vaccines have significantly reduced RV-associated morbidityand mortalities in several countries like the United States and Mexico while vaccine trials have proved efficacious in Ghana and other developingcountries. However, there is paucity of data on RV infection in Cameroon where diarrhea is a major childhood disease. Methods: A total of 534 stool specimens collected between January 2003 and December 2004 from children with acute gastroenteritis in five health districts in the NWR of Cameroon were screened for group A human rotavirus antigen by ELISA and their electropherotypes determined by Polyacrylamide gel electrophoresis.Results: RV was detected in 153 (28.7%) diarrheic specimens with infection occurring throughout the year, being more commonin children under two years of age (P < 0.01) with the highest incidence in the 7-9 months age group (P <0.05). Sub clinical infections (9%)occurred mostly in children aged 0 - 6 months old (P<0.01). Source of drinking water was not associated with RV infection. Elevenelectropherotype patterns were detected with predominance of long electropherotypes (92.8%) and mixed electropherotypes were seen only inhospitalized children. Some isolates showed overlapping or merged genome segments 7 and 8 or 9 and presenting with 10 segments of the RV genome. Conclusion: RV is a significant cause of pediatric diarrhea in the NWR affecting mostly children under 2 years of age. Continuous RVsurveillance and nationwide surveys are recommended to improve the health of young children in Cameroon. More research is needed to fullycharacterize the isolated RV strains.Key words: Rotavirus, diarrhea, molecular epidemiology, electropherotype

Hydrological responses to climate and land use change at watershed scale_ Malaysia

The hydrological effects of climate variation and land use conversion can occur at various spatial scales, but the most important sources of these changes are at the regional or watershed scale. In addition, the managerial and technical measures are primarily implemented at local and watershed scales in order to mitigate adverse impacts of human activities on the renewable resources of the watershed. Therefore, quantitative estimation of the possible hydrological consequences of potential land use and climate changes on hydrological regime at watershed scale is of tremendous importance. This paper focuses on the impacts of climate change as well as land use change on the hydrological processes of river basin based on pertinent published literature which were precisely scrutinized. The various causes, forms, and consequences of such impacts were discussed to synthesize the key findings of literature in reputable sources and to identify gaps in the knowledge where further research is required. Results indicate that the watershed-scale studies were found as a gap in tropical regions. Also, these studies are important to facilitate the application of results to real environment. Watershed scale studies are essential to measure the extent of influences made to the hydrological conditions and understanding of causes and effects of climate variation and land use conversion on hydrological cycle and water resources

Edge-selenated graphene nanoplatelets as durable metal-free catalysts for iodine reduction reaction in dye-sensitized solar cells

Metal-free carbon-based electrocatalysts for dye-sensitized solar cells (DSSCs) are sufficiently active in Co(II)/Co(III) electrolytes but are not satisfactory in the most commonly used iodide/triiodide (I-/I-3(-)) electrolytes. Thus, developing active and stable metal-free electrocatalysts in both electrolytes is one of the most important issues in DSSC research. We report the synthesis of edge-selenated graphene nanoplatelets (SeGnPs) prepared by a simple mechanochemical reaction between graphite and selenium (Se) powders, and their application to the counter electrode (CE) for DSSCs in both I-/I-3(-) and Co(II)/Co(III) electrolytes. The edge-selective doping and the preservation of the pristine graphene basal plane in the SeGnPs were confirmed by various analytical techniques, including atomic-resolution transmission electron microscopy. Tested as the DSSC CE in both Co(bpy)(3)(2+/3+) (bpy = 2,2'-bipyridine) and I-/I-3(-) electrolytes, the SeGnP-CEs exhibited outstanding electrocatalytic performance with ultimately high stability. The SeGnP-CE-based DSSCs displayed a higher photovoltaic performance than did the Pt-CE-based DSSCs in both SM315 sensitizer with Co(bpy)(3)(2+/3+) and N719 sensitizer with I-/I-3(-) electrolytes. Furthermore, the I-3(-) reduction mechanism, which has not been fully understood in carbon-based CE materials to date, was clarified by an electrochemical kinetics study combined with density functional theory and nonequilibrium Green's function calculations.ope

Quantitative Measure to Differentiate Wicket Spike from Interictal Epileptiform Discharges

A number of benign EEG patterns are often misinterpreted as interictal epileptiform discharges (IEDs) because of their epileptiform appearances, one of them is wicket spike. Differentiating wicket spike from IEDs may help in preventing epilepsy misdiagnosis. The temporal location of IEDs and wicket spike were chosen from 143 EEG recordings. Amplitude, duration and angles were measured from the wave triangles and were used as the variables. In this study, linear discriminant analysis is used to create the formula to differentiate wicket spike from IEDs consisting spike and sharp waves. We obtained a formula with excellent accuracy. This study emphasizes the need for objective criteria to distinguish wicket spike from IEDs to avoid misreading of the EEG and misdiagnosis of epilepsy

Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells

AbstractPiperlongumine (PL), isolated from the fruit of Long pepper, Piper longum, is a cancer-inhibiting compound that selectively kills tumor cells while sparing their normal counterparts. Here we evaluated the efficacy with which PL suppresses malignant B cells derived from a newly developed, double-transgenic mouse model of human endemic Burkitt lymphoma (BL), designated mCD40-LMP1/iMycEμ. PL inhibited tumor cell proliferation in a concentration-dependent manner and induced apoptosis of neoplastic but not normal B cells. Treatment with PL resulted in downregulation of EBV-encoded LMP1, cellular Myc, constitutive NF-κB activity, and a host of LMP1-Myc-NF-κB-regulated target genes including Aurka, Bcat1, Bub1b, Ccnb1, Chek1, Fancd2, Tfrc and Xrcc6. Of note, p21Cip1-encoding Cdkn1a was suppressed independent of changes in Trp53 mRNA levels and p53 DNA-binding activity. Considering the central role of the LMP1–NF-κB–Myc axis in B-lineage neoplasia, these findings further our understanding of the mechanisms by which PL inhibits B-lymphoma and provide a preclinical rationale for the inclusion of PL in new interventions in blood cancers

Trend analysis of major hydroclimatic variables in the Langat River basin, Malaysia

Trend analyses of monthly, seasonal and annual rainfall, air temperature, and streamflow were performed using Mann‐Kendall test within the Langat River basin to identify gradual trends and abrupt shifts for 1980 − 2010. Annual rainfall showed an increasing trend in upstream flow, a combination of decreasing and increasing trends in middle stream flow, and a decreasing trend in downstream flow. Monthly rainfall in most months displayed an insignificant increasing trend upstream. Stations with significant increasing trends showed larger trends in summer than those of other seasons. However, they were similar to the trends observed in annual rainfall. Annual minimum air temperature showed a significant decreasing trend upstream and significant increasing trends in the middle stream and downstream areas. Annual maximum air temperature portrayed increasing trends in both upstream and middle stream areas, and a decreasing trend for the downstream area. Both monthly and seasonal maximum air temperatures exhibited an increasing trend midstream, whereas they demonstrated trends of both decreasing and/or increasing temperatures at upstream and downstream areas. Annual streamflow in upper, middle and lower catchment areas exhibited significant increasing trend at the rates of 0.036, 0.023 and 0.001 × 103 m3/y at α = 0.01, respectively. Seasonal streamflow in the upstream, midstream and downstream areas displayed an increasing trend for spring (0.55, 0.33 and 0.013 m3/y respectively) and summer (0.51, 0.37, 0.018 m3/y respectively). The greatest magnitude of increased streamflow occurred in the spring (0.54 m3/y). Significant increasing trends of monthly streamflow were noticed in January and August, but insignificant trends were found in May, September and November at all stations. Annual streamflow records at the outlet of the basin were positively correlated with the annual rainfall variable. This study concludes that the climate of the Langat River basin has been getting wetter and warmer during 1980‐2010

High-dose Immunoglobulin Infusion for Thrombotic Thrombocytopenic Purpura Refractory to Plasma Exchange and Steroid Therapy

The outcomes of the treatment of thrombotic thrombocytopenic purpura (TTP) have been shown to be improved by the administration of plasma exchange. However, treatment options are currently limited for cases refractory to plasma exchange. The autoantibodies that block the activity of ADAMTS13 have been demonstrated to play a role in the pathogenesis of TTP; therefore, high-dose immunoglobulin, which can neutralize these autoantibodies, may be useful for refractory TTP. However, successful treatment with high-dose immunoglobulin for TTP refractory to plasma exchange and corticosteroids has yet to be reported in Korea. Herein, we describe a refractory case which was treated successfully with high-dose immunoglobulin. A 29-year-old male diagnosed with TTP failed to improve after plasma exchange coupled with additional high-dose corticosteroid therapy. As a salvage treatment, we initiated a 7-day regimen of high-dose immunoglobulin (400 mg/kg) infusions, which resulted in a complete remission, lasting up to the last follow-up at 18 months. High-dose immunoglobulin may prove to be a useful treatment for patients refractory to plasma exchange; it may also facilitate recovery and reduce the need for plasma exchange