Descriptors for terpene esters from chromatographic and partition measurements: Estimation of human odor detection thresholds

We have used gas chromatographic retention data together with other data to obtain Abraham descriptors for 30 terpene esters. These include the air-water partition coefficient, as log Kw, for which no experimental values are available for any terpene ester. The other descriptors are the ester dipolarity, S, the hydrogen bond basicity, B, (the ester hydrogen bond acidity is zero for the esters studied), and L the logarithm of the air-hexadecane partition coefficient. Both S and B are larger than those for simple aliphatic esters, as expected from the terpene ester structures that include ring systems and ethylenic double bonds. These descriptors can then be used to obtain a large number of physicochemical and environmental properties of terpene esters. We have analyzed experimental results on human odor detection thresholds and have constructed another equation for the calculation of these thresholds, to go with a previous equation that we have reported. Then the descriptors for terpene esters can be used to estimate the important odor detection thresholds

Traces of the (m)other: deconstructing hegemonic historical narrative in Teat(r)o Oficina Uzyna Uzona's Os Sertões

This article focuses on the way in which renowned São Paulo-based theatre company Teat(r)o Oficina Uzyna Uzona deconstructs hegemonic historical narrative in their 2000 - 2007 25 hour-long production of Euclides da Cunha’s seminal Brazilian novel Os sertões (“Rebellion in the Backlands”), an account of the War of Canudos (1896-1897), the first major act of State terrorism carried out by the nascent Brazilian Federal Government on the country’s subaltern population. The Teat(r)o Oficina’s epic adaptation fuses events from the colonial period, the military dictatorship and contemporary 21st Century São Paulo to relate the repetitive cycles of misappropriation, oppression and resistance that have characterized the history of Brazil and its people over the centuries. However, any fatalistic view of victimhood as an essential aspect of Brazilian subjectivity is radically challenged by the vibrant, rhythmic, material impact of the theatrical super-signs underpinning the performance text. Drawing on Julia Kristeva’s notion of the semiotic - the pre-linguistic, illogical, rhythmical materialism of language intimately related to a primordial relationship with the abject mother – I shall suggest that it is the rhythmic, libidinal force of the performance and its extensive use of the cultural manifestations of Brazil’s subaltern population that imbues Os Sertões with the silent presence-as-absence of the abject Brazilian (M)Other – the Black, Indigenous and Mestiza matriarchal line whose alternative discourse is often barred from hegemonic accounts of Brazilian historiography. Her silent heritage is embodied on stage by the members of the Oficina, who reclaim an alienating national heritage for themselves by transforming the often tragic tale of Brazil’s past into a joyous celebration of tenacious vitality

As redes editoriais do ILARI no Rio da Prata e a modernização das ciências sociais durante a Guerra Fria cultural latino-americana

O Instituto Latino-Americano de Relações Internacionais (ILARI), financiado pela Fundação Ford e vinculado ao controverso Congresso pela Liberdade da Cultura (CLC), estimulou desde seu início, em 1965, a renovação das ciências sociais na América Latina por meio de encontros e pesquisas, bem como da publicação da revista Aportes e de acordos com editoras locais ”“ como Paidós e Jorge Álvares, de Buenos Aires, e Alfa, de Montevidéu. Este trabalho aborda as políticas editoriais do ILARI, que se transformaram em um canal de legitimação e promoção da figura do cientista social, cuja emergência deve ser compreendida no marco da Guerra Fria cultural, marcada pelos debates sobre as possíveis vias de desenvolvimento das sociedades periféricas. Essa figura, que acaba por suplantar a do ensaísta e disputa espaço com as do intelectual comprometido e do intelectual revolucionário, aparece legitimada por um discurso sobre a modernização, associado a uma produção “objetiva” de saberes

As disputas regionais no Brasil do ponto de vista de São Paulo

Resenha de: WEISTEIN, Bárbara. A cor da modernidade: a branquitude e a formação da identidade paulista. São Paulo: Edusp, 2022. 655 p

Patterns of Individual Shopping Behavior

Much of economic theory is built on observations of aggregate, rather than individual, behavior. Here, we present novel findings on human shopping patterns at the resolution of a single purchase. Our results suggest that much of our seemingly elective activity is actually driven by simple routines. While the interleaving of shopping events creates randomness at the small scale, on the whole consumer behavior is largely predictable. We also examine income-dependent differences in how people shop, and find that wealthy individuals are more likely to bundle shopping trips. These results validate previous work on mobility from cell phone data, while describing the unpredictability of behavior at higher resolution.Comment: 4 pages, 5 figure

Muita politicagem, pouca política os problemas da polícia são

A partir de uma tematização crítica do que seja, ou possa ser, o "crime organizado", este ensaio contextualiza e desenvolve a trajetória profissional de um(a) hipotético(a) jovem policial, compartilhando uma visão de base etnográfica sobre as "frágeis fronteiras" entre conveniência, convivência e conivência diante de atividades ilícitas. Segue a pista de uma expressão cotidiana dos policiais fluminenses: "a polícia tem vários patrões", que serve para criticar, contemporizar, explicar ou justificar o que compreendem como o "comprometimento" ou o "envolvimento" de policiais com os mais diversos interesses, incluindo os que se associam ao chamado "crime organizado". Compartilha elementos de um diagnóstico da clientelização policial que contextualizam e conformam as condições de possibilidade do uso do mandato policial para fins particulares e suas implicações.The presente essay departs from a critical appraisal of what is, or would be, the "organized crime" to develop and contextualize the professional trajectory of a hypothetical young police officer, showing an ethnographic perception of the "frail frontiers" that separate police convenience, coexistence and connivance with illicit activities. It follows the lead provided by a common saying of Rio de Janeiro police officers - "the police have many bosses" - in order to criticize, palliate, explain or justify their "connection" or "involvement" with a wide variety of interests, including some that are associated with the so-called "organized crime". It also mentions the elements of a diagnosis of police "clientelization", which contextualize and shape the conditions of the possibility of using the police mandate for private purposes and its implications

Da tradução de “Uma revolução conservadora na edição”, de Pierre Bourdieu

Esta tradução do artigo “Une révolution conservatrice dans l’édition”, de Pierre Bourdieu, requer alguns esclarecimentos

A New Strategy To Identify Rare Blood Donors: Single Polymerase Chain Reaction Multiplex Snapshot Reaction For Detection Of 16 Blood Group Alleles

Background. As an alternative to phenotyping, large-scale DNA-based assays, which are feasible for high-throughput donor red blood cell typing, were developed for determination of blood group polymorphisms. However, high-throughput genotyping platforms based on these technologies are still expensive and the inclusion of single nucleotide polymorphisms and analysis of the alleles depend on the manufacturer's determination. To overcome this limitation and in order to develop an assay to enable the screening of rare donors, we developed a SNaPshot assay for analysis of nine single nucleotide polymorphisms related to antigens that are difficult to assess using conventional serology. Materials and methods. The single polymerase chain reaction multiplex SNaPshot reaction was optimized to identify nine single nucleotide polymorphisms determining 16 alleles: KEL*3/KEL*4, KEL*6/KEL*7, DI*1/DI*2, DI*3/DI*4, YT*1/YT*2, CO*1/CO*2, DO*1/DO*2, DO*4, DO*5. We designed a single multiplex PCR with primers encompassing the blood group single nucleotide polymorphisms and performed an internal reaction with probe primers able to discriminate the alleles after fragment analysis. The SNaPshot assay was validated with 140 known alleles previously determined by PCR restriction fragment length polymorphism. Results. We were able to simultaneous detect nine single nucleotide polymorphisms defining 16 blood group alleles on an assay based on a multiplex PCR combined with a single base extension using genomic DNA. Discussion. This study demonstrates a robust genotyping strategy for conducting rare donor screening which can be applied in blood centers and could be an important tool for identifying antigen-negative donors and, therefore, for providing rare blood. © SIMTI Servizi Srl.12SUPPL.1s256s263Jungbauer, C., Routine use of DNA testing for red cell antigens in blood centres (2011) Transfus Apher Sci, 45, pp. 61-68Nance, S.T., How to find, recruit and maintain rare blood donors (2009) Curr Opin Hematol, 16, pp. 503-508Veldhuisen, B., Van Der Schoot, C.E., De Haas, M., Blood group genotyping: From patient to high-throughput donor screening (2009) Vox Sang, 97, pp. 198-206Moulds, J.M., Future of molecular testing for red blood cell antigens (2010) Clin Lab Med, 30, pp. 419-429Patnaik, S.K., Helmberg, W., Blumenfeld, O.O., BGMUT: NCBI dbRBC database of allelic variations of genes encoding antigens of blood group systems (2012) Nucleic Acids Res, 40, pp. D1023-D1029Vallone, P.M., Butler, J.M., AutoDimer: A screening tool for primer-dimer and hairpin structures (2004) Biotechniques, 37, pp. 226-231Baleotti Jr., W., Rios, M., Reid, M.E., Dombrock gene analysis in Brazilian people reveals novel alleles (2006) Vox Sang, 91, pp. 81-87Rios, M., Hue-Roye, K., Oyen, R., Insights into the Holleyand Joseph- phenotypes (2002) Transfusion, 42, pp. 52-58Baleotti Jr., W., Rios, M., Reid, M.E., A novel DI*A allele without the Band 3-Memphis mutation in Amazonian Indians (2003) Vox Sang, 84, pp. 326-330Arnoni, C., Latini, F.R.M., Person, R.M., Padronização das técnicas de PCR-RFLP para genotipagem dos alelos KEL*3/ KEL*4 e KEL*5/KEL*6 (2011) Rev Bras Hematol Hemoter, 33 (SUPPL.2), pp. 332-488Baleotti Jr., W., Suzuki, R.B., Ruiz, M., A PCR-RFLP strategy for Wright typing (2011) Rev Bras Hematol Hemoter, 33 (SUPPL. 2), pp. 332-488Brazilian Real - United States Dollar Exchange Rate from Central Bank of Brazil, , http://www4.bcb.gov.br/pec/taxas, April 1st to April 30th, 27/03/2013Daniels, G., The molecular genetics of blood group polymorphism (2009) Hum Genet, 126, pp. 729-742Logdberg, L., Reid, M.E., Zelinski, T., Human blood group genes 2010: Chromosomal locations and cloning strategies revisited (2011) Transfus Med Rev, 25, pp. 36-46Di Cristofaro, J., Silvy, M., Chiaroni, J., Bailly, P., Single PCR multiplex SNaPshot reaction for detection of eleven blood group nucleotide polymorphisms: Optimization, validation, and one year of routine clinical use (2010) J Mol Diagn, 12, pp. 453-460Ferri, G., Pelotti, S., Multiplex ABO genotyping by minisequencing (2009) Methods Mol Biol, 496, pp. 51-58Palacajornsuk, P., Halter, C., Isakova, V., Detection of blood group genes using multiplex SNaPshot method (2009) Transfusion, 49, pp. 740-749Silvy, M., Simon, S., Gouvitsos, J., Weak D and DEL alleles detected by routine SNaPshot genotyping: Identification of four novel RHD alleles (2011) Transfusion, 51, pp. 401-411Silvy, M., Di Cristofaro, J., Beley, S., Identification of RHCE and KEL alleles in large cohorts of Afro-Caribbean and Comorian donors by multiplex SNaPshot and fragment assays: A transfusion support for sickle cell disease patients (2011) Br J Haematol, 154, pp. 260-270Pastinen, T., Kurg, A., Metspalu, A., Minisequencing: A specific tool for DNA analysis and diagnostics on oligonucleotide arrays (1997) Genome Res, 7, pp. 606-614Syvanen, A.C., From gels to chips: "Minisequencing" primer extension for analysis of point mutations and single nucleotide polymorphisms (1999) Hum Mutat, 13, pp. 1-10Information notebook (2011) Blood and Hemoderivates Brasília, , Ministério da Saúde. Secretaria de Atenção à Saúde. Coordenação-Geral de Sangue e Hemoderivados. Hemotherapy production. Unified Health System - SUS Brazil - (Public and private contractors). Private non-contracted services by Unified Health System (SUS Brazil). 4th edSantos, N.P., Ribeiro-Rodrigues, E.M., Ribeiro-Dos-Santos, A.K., Assessing individual interethnic admixture and population substructure using a 48-insertion-deletion (INSEL) ancestry-informative marker (AIM) panel (2010) Hum Mutat, 31, pp. 184-190Storry, J.R., Human blood groups: Inheritance and importance in transfusion medicine (2003) J Infus Nurs, 26, pp. 367-37

INFORMATION SECURITY AND QUALITY MANAGEMENT SYSTEMS INTEGRATION: CHALLENGES AND CRITICAL FACTORS

Implementing a new management system in organizations that already have a certified management system can be challenging. This research discussed enabler factors that influence the integration of an information security management system certified following ISO 27001 with a quality management system certified following ISO 9001. Five factors were identified as the basis of this research: Implementation Model, Human Resources, Resources Availability, Standard Issues, and Standards Integration. Four factors were validated through the qualitative study with consultants specialized in implementing and integrating these standards. Then, by prioritizing these factors through the Analytic Hierarchy Process method, it was found that the most relevant aspect is Standards Integration for the managers from the institution object of study. For specialist consultants, the most pertinent factor is Human Resources