434 research outputs found
Resolving photon number states in a superconducting circuit
Electromagnetic signals are always composed of photons, though in the circuit
domain those signals are carried as voltages and currents on wires, and the
discreteness of the photon's energy is usually not evident. However, by
coupling a superconducting qubit to signals on a microwave transmission line,
it is possible to construct an integrated circuit where the presence or absence
of even a single photon can have a dramatic effect. This system is called
circuit quantum electrodynamics (QED) because it is the circuit equivalent of
the atom-photon interaction in cavity QED. Previously, circuit QED devices were
shown to reach the resonant strong coupling regime, where a single qubit can
absorb and re-emit a single photon many times. Here, we report a circuit QED
experiment which achieves the strong dispersive limit, a new regime of cavity
QED in which a single photon has a large effect on the qubit or atom without
ever being absorbed. The hallmark of this strong dispersive regime is that the
qubit transition can be resolved into a separate spectral line for each photon
number state of the microwave field. The strength of each line is a measure of
the probability to find the corresponding photon number in the cavity. This
effect has been used to distinguish between coherent and thermal fields and
could be used to create a photon statistics analyzer. Since no photons are
absorbed by this process, one should be able to generate non-classical states
of light by measurement and perform qubit-photon conditional logic, the basis
of a logic bus for a quantum computer.Comment: 6 pages, 4 figures, hi-res version at
http://www.eng.yale.edu/rslab/papers/numbersplitting_hires.pd
Implementation of a Toffoli Gate with Superconducting Circuits
The quantum Toffoli gate allows universal reversible classical computation.
It is also an important primitive in many quantum circuits and quantum error
correction schemes. Here we demonstrate the realization of a Toffoli gate with
three superconducting transmon qubits coupled to a microwave resonator. By
exploiting the third energy level of the transmon qubit, the number of
elementary gates needed for the implementation of the Toffoli gate, as well as
the total gate time can be reduced significantly in comparison to theoretical
proposals using two-level systems only. We characterize the performance of the
gate by full process tomography and Monte Carlo process certification. The gate
fidelity is found to be %.Comment: 4 pages, 5figure
Preparation and Measurement of Three-Qubit Entanglement in a Superconducting Circuit
Traditionally, quantum entanglement has played a central role in foundational
discussions of quantum mechanics. The measurement of correlations between
entangled particles can exhibit results at odds with classical behavior. These
discrepancies increase exponentially with the number of entangled particles.
When entanglement is extended from just two quantum bits (qubits) to three, the
incompatibilities between classical and quantum correlation properties can
change from a violation of inequalities involving statistical averages to sign
differences in deterministic observations. With the ample confirmation of
quantum mechanical predictions by experiments, entanglement has evolved from a
philosophical conundrum to a key resource for quantum-based technologies, like
quantum cryptography and computation. In particular, maximal entanglement of
more than two qubits is crucial to the implementation of quantum error
correction protocols. While entanglement of up to 3, 5, and 8 qubits has been
demonstrated among spins, photons, and ions, respectively, entanglement in
engineered solid-state systems has been limited to two qubits. Here, we
demonstrate three-qubit entanglement in a superconducting circuit, creating
Greenberger-Horne-Zeilinger (GHZ) states with fidelity of 88%, measured with
quantum state tomography. Several entanglement witnesses show violation of
bi-separable bounds by 830\pm80%. Our entangling sequence realizes the first
step of basic quantum error correction, namely the encoding of a logical qubit
into a manifold of GHZ-like states using a repetition code. The integration of
encoding, decoding and error-correcting steps in a feedback loop will be the
next milestone for quantum computing with integrated circuits.Comment: 7 pages, 4 figures, and Supplementary Information (4 figures)
Study of decays to the final state and evidence for the decay
A study of decays is performed for the first time
using data corresponding to an integrated luminosity of 3.0
collected by the LHCb experiment in collisions at centre-of-mass energies
of and TeV. Evidence for the decay
is reported with a significance of 4.0 standard deviations, resulting in the
measurement of
to
be .
Here denotes a branching fraction while and
are the production cross-sections for and mesons.
An indication of weak annihilation is found for the region
, with a significance of
2.4 standard deviations.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-022.html,
link to supplemental material inserted in the reference
The Mind’s Eye on Personal Profiles: A Cognitive Perspective on Profile Elements that Inform Initial Trustworthiness Assessments in Virtual Project Teams
Rusman, E., Van Bruggen, J., Sloep, P., Valcke, M., & Koper, R. (2013). The Mind’s Eye on Personal Profiles: A Cognitive Perspective on Profile Elements that Inform Initial Trustworthiness Assessments and Social Awareness in Virtual Project Teams. Computer Supported Cooperative Work (CSCW), 22(2-3), 159-179.Collaboration in virtual project teams heavily relies on interpersonal trust, for which perceived trustworthiness is an important determinant. This study provides insight in the information that trustors value to assess a trustee’s professional trustworthiness in the initial phase of a virtual project team. We expect trustors in virtual teams to value those particular information elements that provide them with relevant cues of trust warranting properties of a trustee. We identified a list of commonly highly valued information elements to inform trustworthiness assessments (n=226). We then analysed explanations for preferences with the help of a theory-grounded coding scheme. Results show that respondents value those particular information elements that provide them with multiple cues to assess the trustworthiness of a trustee. This enables them to become aware of and assess the trustworthiness of another. Information elements that provide unique cues could not be identified. Insight in these information preferences can inform the design of artefacts, such as personal profile templates, to support acquaintanceships in the initial phase of a virtual project team
Demonstration of Two-Qubit Algorithms with a Superconducting Quantum Processor
By harnessing the superposition and entanglement of physical states, quantum
computers could outperform their classical counterparts in solving problems of
technological impact, such as factoring large numbers and searching databases.
A quantum processor executes algorithms by applying a programmable sequence of
gates to an initialized register of qubits, which coherently evolves into a
final state containing the result of the computation. Simultaneously meeting
the conflicting requirements of long coherence, state preparation, universal
gate operations, and qubit readout makes building quantum processors
challenging. Few-qubit processors have already been shown in nuclear magnetic
resonance, cold ion trap and optical systems, but a solid-state realization has
remained an outstanding challenge. Here we demonstrate a two-qubit
superconducting processor and the implementation of the Grover search and
Deutsch-Jozsa quantum algorithms. We employ a novel two-qubit interaction,
tunable in strength by two orders of magnitude on nanosecond time scales, which
is mediated by a cavity bus in a circuit quantum electrodynamics (cQED)
architecture. This interaction allows generation of highly-entangled states
with concurrence up to 94%. Although this processor constitutes an important
step in quantum computing with integrated circuits, continuing efforts to
increase qubit coherence times, gate performance and register size will be
required to fulfill the promise of a scalable technology.Comment: 6 pages, 1 table, 4 figures, and Supplementary Information (3 pages,
3 figures); Expanded author list, updated references, and minor improvements
to text and figure
Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis
O-linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAc addition to numerous cellular proteins including transcription and nuclear pore complexes and plays a key role in cellular signaling. One differentially spliced isoform of OGT is normally targeted to mitochondria (mOGT) but is quite cytotoxic when expressed in cells compared with the ncOGT isoform. To understand the basis of this selective cytotoxicity, we constructed a fully functional ecdysone-inducible GFP–OGT. Elevated GFP–OGT expression induced a dramatic increase in intracellular O-GlcNAcylated proteins. Furthermore, enhanced OGT expression efficiently triggered programmed cell death. Apoptosis was dependent upon the unique N-terminus of mOGT, and its catalytic activity. Induction of mOGT expression triggered programmed cell death in every cell type tested including INS-1, an insulin-secreting cell line. These studies suggest that deregulated activity of the mitochondrially targeted mOGT may play a role in triggering the programmed cell death observed with diseases such as diabetes mellitus and neurodegeneration
Expansion and subfunctionalisation of flavonoid 3',5'-hydroxylases in the grapevine lineage
<p>Abstract</p> <p>Background</p> <p>Flavonoid 3',5'-hydroxylases (F3'5'Hs) and flavonoid 3'-hydroxylases (F3'Hs) competitively control the synthesis of delphinidin and cyanidin, the precursors of blue and red anthocyanins. In most plants, <it>F3'5'H </it>genes are present in low-copy number, but in grapevine they are highly redundant.</p> <p>Results</p> <p>The first increase in <it>F3'5'H </it>copy number occurred in the progenitor of the eudicot clade at the time of the γ triplication. Further proliferation of <it>F3'5'H</it>s has occurred in one of the paleologous loci after the separation of Vitaceae from other eurosids, giving rise to 15 paralogues within 650 kb. Twelve reside in 9 tandem blocks of ~35-55 kb that share 91-99% identity. The second paleologous <it>F3'5'H </it>has been maintained as an orphan gene in grapevines, and lacks orthologues in other plants. Duplicate <it>F3'5'H</it>s have spatially and temporally partitioned expression profiles in grapevine. The orphan <it>F3'5'H </it>copy is highly expressed in vegetative organs. More recent duplicate <it>F3'5'H</it>s are predominately expressed in berry skins. They differ only slightly in the coding region, but are distinguished in the structure of the promoter. Differences in <it>cis</it>-regulatory sequences of promoter regions are paralleled by temporal specialisation of gene transcription during fruit ripening. Variation in anthocyanin profiles consistently reflects changes in the <it>F3'5'H </it>mRNA pool across different cultivars. More <it>F3'5'H </it>copies are expressed at high levels in grapevine varieties with 93-94% of 3'5'-OH anthocyanins. In grapevines depleted in 3'5'-OH anthocyanins (15-45%), fewer <it>F3'5'H </it>copies are transcribed, and at lower levels. Conversely, only two copies of the gene encoding the competing F3'H enzyme are present in the grape genome; one copy is expressed in both vegetative and reproductive organs at comparable levels among cultivars, while the other is transcriptionally silent.</p> <p>Conclusions</p> <p>These results suggest that expansion and subfunctionalisation of <it>F3'5'H</it>s have increased the complexity and diversification of the fruit colour phenotype among red grape varieties.</p
Inter-organizational governance and trilateral trust building: a case study of crowdsourcing-based open innovation in China
In a case study of a Chinese crowdsourcing intermediary, we explore the impact of inter-organizational governance on trilateral trust-building. We show that formal control and relational governance mechanisms are essential for swift and knowledge-based trust in R&D crowdsourcing. The case also indicates that Chinese businesses continue to use guanxi (informal personal connections) as a relational and contingent mechanism to maintain affect-based trust, but guanxi is shown to inhibit the growth of Internet-based crowdsourcing for open innovation in China
Sugar and abscisic acid signaling orthologs are activated at the onset of ripening in grape
The onset of ripening involves changes in sugar metabolism, softening, and color development. Most understanding of this process arises from work in climacteric fruits where the control of ripening is predominately by ethylene. However, many fruits such as grape are nonclimacteric, where the onset of ripening results from the integration of multiple hormone signals including sugars and abscisic acid (ABA). In this study, we identified ten orthologous gene families in Vitis vinifera containing components of sugar and ABA-signaling pathways elucidated in model systems, including PP2C protein phosphatases, and WRKY and homeobox transcription factors. Gene expression was characterized in control- and deficit-irrigated, field-grown Cabernet Sauvignon. Sixty-seven orthologous genes were identified, and 38 of these were expressed in berries. Of the genes expressed in berries, 68% were differentially expressed across development and/or in response to water deficit. Orthologs of several families were induced at the onset of ripening, and induced earlier and to higher levels in response to water deficit; patterns of expression that correlate with sugar and ABA accumulation during ripening. Similar to field-grown berries, ripening phenomena were induced in immature berries when cultured with sucrose and ABA, as evidenced by changes in color, softening, and gene expression. Finally, exogenous sucrose and ABA regulated key orthologs in culture, similar to their regulation in the field. This study identifies novel candidates in the control of nonclimacteric fruit ripening and demonstrates that grape orthologs of key sugar and ABA-signaling components are regulated by sugar and ABA in fleshy fruit
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