9 research outputs found
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
- Author
- Abbas Sh
- Abbas Sh
- Abbassi Oa
- Abbott T
- Abdelgadir Am
- Abdelrahman A
- Abdelrahman M
- Abdelrahman M
- Abdelwahed A
- Abellan M
- Abellán Am
- Abellán Am
- Abulafi M
- Acharya A
- Acosta A
- Adam Me
- Adams Re
- Adegbola So
- Adegbola So
- Adimonye A
- Adnan M
- Afshar S
- Agresta F
- Agua Ia
- Aguayo Jl
- Agudo Ar
- Ahad A
- Ahel J
- Ahern Dp
- Ahmad A
- Ahmed B
- Ahmed G
- Ahmed Os
- Ahmed Os
- Ahmed S
- Ainsworth P
- Ais G
- Ais G
- Aisoni F
- Akbari K
- Akhtar K
- Akinsola O
- Akram F
- Al-Faham Z
- Al-Khafaji N
- Al-Khyatt W
- Al-Musawi S
- Al-Sarireh B
- Al-Sheikh M
- Alagna V
- Alani M
- Alberca-Paramo A
- Aldrey I
- Alexander R
- Alhammali T
- Alhammali T
- Ali M
- Aljorfi A
- Allen M
- Allington J
- Alonzo A
- Alshafei A
- Altomare Ma
- Alvarez Cm
- Alvarez E
- Alvarez-Gallego M
- Amaducci E
- Amarasinghe R
- Amayo A
- Ambrona-Zafra D
- Amin V
- Ammendola M
- Amtul N
- Amtul N
- Amuthalingam T
- Anandan L
- Anania G
- Anania M
- Anderson Dj
- Anderson O
- Andolfi E
- Andreani Sm
- Andreani Sm
- Andrews B
- Ang A
- Ang A
- Angelieri D
- Angelini M
- Angrisani M
- Anguita F
- Ansaloni L
- Ansari A
- Aravind B
- Archer Je
- Arcuri Ga
- Arcuri Ga
- Aremu Ma
- Arenal-Vera Jj
- Aresu S
- Aresu S
- Argenio G
- Argenti F
- Armellini A
- Arnau M
- Arredondo J
- Arroyo A
- Arshad F
- Arunachalam S
- Arunachalam S
- Arunachalam S
- Aruparayil N
- Asensio-Gomez L
- Ashmore Dl
- Ashmore Dl
- Ashour O
- Ashraf N
- Asmadi Aa
- Assaf N
- Assaf N
- Assaf N
- Athersmith Mj
- Atzeni J
- Avalapati H
- Avanzolini A
- Avanzolini A
- Awokoya Oo
- Ayllón-Gámez S
- Ayube-Brown J
- Azabdaftari A
- Azevedo J
- Azevedo Jm
- Baddams Ts
- Badenoch T
- Badii B
- Badran A
- Baeza-Murcia M
- Bagga R
- Baginski A
- Bailey Ja
- Bailey S
- Bailey S
- Bailon-Cuadrado M
- Baird C
- Bairos F
- Baker B
- Balai Ej
- Balasubramaniam A
- Balestra F
- Ball A
- Ball A
- Ball A.
- Ballabio M
- Ballester Mm
- Bandyopadhyay Sk
- Banks A
- Bansal H
- Baraghini M
- Barbosa L
- Barker T
- Barker T
- Barnieh W
- Baronio G
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- Barrie A
- Barter Ca
- Bartoli A
- Bascuas-Rodrigo B
- Baseggio M
- Bastianpillai J
- Bawa S
- Baz-Figueroa C
- Bazán-Hinojo Mc
- Bazán-Hinojo Mc
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- Bedoya S
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- Beltran-De-Heredia J
- Beltran-De-Heredia J
- Belvedere A
- Benevento A
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- Bernal-Sprekelsen Jc
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- Bevan Ke
- Bevan V
- Beverstock A
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- Bhanderi S
- Bhanderi S
- Bhanderi S
- Bhanderi S.
- Bhangu A. Nepogodiev D
- Bhangu A
- Bhangu A
- Bhangu A
- Bhangu A
- Bhargava A
- Biancafarina A
- Biancafarina A
- Bianchi Cl
- Bianchi Cl
- Bianco A
- Bilku D
- Birindelli A
- Birindelli A
- Birindelli A
- Blackford Od
- Blackwell J
- Blake L
- Blanco F
- Blanco-Colino R
- Blanco-Colino R
- Blanco-Colino R
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- Blazeby Jm
- Blencowe N. S.
- Blencowe Ns
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- Blencowe Ns
- Boddy Ap
- Boereboom C
- Bogdan M
- Bohra P
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- Boland M
- Bolger Jc
- Bolger Jc
- Bolton W
- Bolzon S
- Bond S
- Bond-Smith G
- Bondurri A
- Bonfante P
- Bonomo M
- Borg Cm
- Borges Fc
- Borghi F
- Borghol K
- Boshier Pr
- Botelho P
- Bowen J
- Bowerman H
- Bowley D
- Bowman Cr
- Bowman Cr
- Boyd-Carson H
- Boza K
- Bradshaw Cj
- Branagan G
- Bravo-Gutiérrez Af
- Bravo-Gutiérrez Af
- Brennan S
- Brett M
- Brewer H
- Brewer Hk
- Brewer Hk
- Brews R
- Brien Jo
- Bronder C
- Brown A
- Brown Ag
- Brown Ce
- Brown Ce
- Brown Ce
- Brown M
- Brown M
- Brown Od
- Brown R
- Bruce Js
- Brunelli Db
- Bryan Es
- Buckley-Jones S
- Bukhari W
- Bull C
- Bullivant Jk
- Burke J
- Burns Km
- Burnside D
- Busuttil A
- Byrne Be
- Byrnes Ck
- Caballero A
- Caldeira Ab
- Caldwell M
- Callan R
- Calussi M
- Calvo H
- Calvo M
- Cameron Fc
- Campagnaro T
- Campagnaro T
- Campbell U
- Campbell Um
- Campbell W
- Cannata G
- Cannavò M
- Cantafio S
- Capelli P
- Carcoforo P
- Carden Ca
- Carder C
- Cardona R
- Cardoso D
- Carlucci M
- Carney K
- Caro A
- Carral-Freire M
- Carrano Fm
- Carrano Fm
- Cartwright H
- Carvalho Lc
- Carvalho N
- Casimiro C
- Castagnoli G
- Castagnoli G
- Caula C
- Caula C
- Cavallo D
- Cavero A
- Cay P
- Ceccarelli G
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cerdán-Santacruz C
- Cervellera M
- Cesari Mc
- Chalk A
- Chambers B
- Chan D
- Chan T
- Chan Wh
- Chandler Sb
- Chandratreya N
- Chandratreya N
- Chapman J
- Chapman Sj
- Chapple Ks
- Charalabopoulos A
- Charalambous Mp
- Chasty B
- Chatzikonstantinou M
- Chatzikonstantinou M
- Chauhan P
- Chauhan P
- Chauhan P.
- Cheah Wl
- Chean Cs
- Chean Cs
- Checcacci P
- Cheng Sa
- Cheruvu M
- Chessa A
- Chessa A
- Chetta G
- Chetta N
- Chianese G
- Chillitupa Cz
- Chimetto A
- Chin My
- Chishti Ia
- Chitsabesan P
- Chng S
- Choi S
- Chok Sm
- Chok Sm
- Chong B
- Choolani-Bhojwani E
- Choong Jh
- Choong Jh
- Choong Jh
- Chowdhary M
- Chowdhury F
- Chowdhury F
- Choy Ch
- Choy Ch
- Chrastek D
- Christian L
- Christides A
- Christopoulos P
- Chudek D
- Chui K
- Cianchi F
- Cidoncha A
- Cillara N
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- Cillara N
- Cipparrone M
- Cirillo B
- Clark Gl
- Clark S
- Clement Kd
- Clement Kd
- Clements B
- Clements C
- Clements J
- Clements J.
- Clements Ja
- Clements Jd
- Clements Jm
- Clements Jm
- Clements Js
- Clerici F
- Clingan R
- Cloney L
- Clough E
- Coccolini F
- Coccolini F
- Cocorullo G
- Coe Po
- Cohen Ja
- Colangelo E
- Coletta D
- Coletta D
- Coletti M
- Collado-Roura F
- Collier-Wakefield O
- Colombo F
- Colombo F
- Colvin Da
- Colvin Da
- Compagnoni B
- Conci S
- Connelly Tm
- Connor Kl
- Connor Kl
- Connor Mj
- Connor Mj
- Conti D
- Contine Ac
- Contreras Rg
- Contreras-Saiz E
- Cook V
- Cooke F
- Coppola M
- Coratti F
- Corbellini C
- Cordoba E
- Cordoba E
- Cormenzana Ob
- Correia D
- Correia J
- Cortés Gv
- Cosci M
- Cossu F
- Costa Sd
- Costamagna D
- Cotton Ae
- Couch Dg
- Cousins L
- Couso Jr
- Cox M
- Coyle D
- Creasy W
- Cremades P
- Criado Adc
- Crone A
- Crozier J
- Cruccu A
- Cruickshank N
- Cuadrado Mm
- Cucinotta E
- Cuello-Guzmán E
- Cunha P
- Currow C
- Curti R
- Curtis Nj
- Curtis-Martínez C
- Cynthia G
- Cánovas-Moreno G
- D'Ambra L
- D'Amico Fe
- D'Amico Fe
- D'Amico Fe
- D'Auria M
- D'Auria M
- D'Souza N
- Daga O
- Dalmia S
- Dandy R
- Daniels I
- Danquah-Boateng D
- Dar Fa
- Dar Fa
- Dart K
- Das A
- Daureeawoo R
- Davidson Jr
- Davidson S
- Davies Pl
- Davis S
- De Andres U
- De Burgos Cb
- De Chaves-Rodríguez Pg
- De Freitas S
- De Luca E
- De Marchi F
- De Marco P
- De Nardi P
- De Nardi P
- De Nisco C
- De Padua C
- De Prizio M
- De-La-Herranz-Guerrero P
- De-Manzoni-Garberini A
- De-Manzoni-Garberini A
- De-Manzoni-Garberini A
- De-Marchi Ja
- De-Marchi Ja
- De-Soto-Cardenal B
- Dean Ea
- Dean S
- Del Basso C
- Del Pozo E
- Del-Valle-Ruiz Sr
- Delgado-Plasencia Lj
- Delimpalta C
- Delimpalta C
- Delogu D
- Denley S
- Dennison G
- Depalma N
- Deserra A
- Desiderio J
- Devezas V
- Devine Aa
- Dhar M
- Dharamavaram S
- Dhari Aa
- Dhesi S
- Di Cintio A
- Di Franco F
- Di Gioia P
- Di Saverio S
- Di Zitti L
- Diaz A
- Dickson Ea
- Divekar Ga
- Dixon F
- Dobbs S
- Dobson C
- Docherty Ja
- Doherty C
- Dominguez-Sanchez C
- Donaldson G
- Donaldson G
- Donohoe No
- Donohoe No
- Douka E
- Doulias T
- Dova L
- Downey M
- Doyle C
- Doyle C
- Drake T. M.
- Drake Tm
- Drye N
- Du Dt
- Dubois As
- Dubois As
- Dudek Jg
- Dujovne P
- Dujovne P
- Dunning Pg
- Duran-Muñoz-Cruzado Vm.
- Durbacz M
- Dyal A
- Dyson S
- Díaz-Vico T
- Eardley Nj
- Earnshaw L
- Easdon S
- Ebied H
- Echazarreta E
- Edwards Se
- Egan Rj
- Egan Rj
- Eguaras I
- Eiben I
- Eiben Ie
- Eiben P
- El-Masry S
- El-Tayar O
- El-Tayar O
- Elbetti C
- Elgaddal S
- Elia M
- Ellis B
- Elseedawy M
- Elshaer M
- Elshaer M
- Emslie Km
- Engall N
- Engall N
- Engall N
- English Wj
- Ercolani G
- Erdas E
- Erdas E
- Eretta Co
- Escoll-Rufino J
- Escuder J
- Esmail Hd
- Espin-Basany E
- Espin-Basany E
- Espina B
- Espinosa J
- Esteves Mb
- Ettles C
- Evans J
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- Everden A
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- Ezerska E
- Fadel M
- Fahmy Se
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- Fairfield Cj
- Falaschi F
- Falco N
- Fanibi Bf
- Fareleira A
- Farhan-Alanie M
- Farina V
- Faris Ar
- Farrell Sm
- Farrow Ez
- Farrow Ez
- Farrés R
- Fasuyi Ja
- Faulkner G
- Fawzi F
- Fehervari M
- Feleppa C
- Feliu F
- Feo Cv
- Ferguson N
- Fermiñán A
- Fernandes C
- Fernández Ec
- Fernández Md
- Fernández-Candela A
- Fernández-Martínez D
- Fernández-Martínez D
- Fernández-Martínez D
- Feroci F
- Ferrara F
- Ferrara F
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- Ferrer-Vilela I
- Fijo Lm
- Finch Jg
- Finlayson H
- Finotti E
- Fiore L
- Fiorot A
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- Fleming Ta
- Fleres F
- Foers W
- Foley Nm
- Foley Nm
- Fontaine C
- Fontana T
- Fontani A
- Fooks P
- Foppa C
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- Forouzanfar A
- Foschi D
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- Franco M
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- Franklin D
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- Gaines E
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- García M
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- García Na
- García V
- García-Carrero M
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- García-Granero A
- García-Granero A
- García-Gutierrez C
- García-Novoa A
- García-Novoa A
- García-Pérez Jm
- García-Rivera Co
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- Gennai A
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- Ghazala R
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- Giraudo G
- Giubilo C
- Giudicissi R
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- Glasbey Jc
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- Golda T
- Golder Am
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- Gomez-Carmona Z
- Gomez-Facundo H
- Gomez-Rosado Jc
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- Gonzálvez-Guardiola P
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- Grandi S
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- Graveston J
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- Griffith Jp
- Griffiths E
- Griffiths Ea
- Griffiths Np
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- Griggs R
- Grimaldo Eg
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- Gurung S
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- Haines S
- Hajibandeh S
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- Hamelmann Rn
- Hanif Z
- Hanley C
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- Hanna T
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- Hollyman M
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- Horsfield E
- Howie Ee
- Hraishawi I
- Huang J
- Hudson-Peacock Nj
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- Hunter I
- Hureibi Ka
- Hureibi Ka
- Hussain A
- Hussain N
- Hussaini Sa
- Hussein A
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- Hutchinson B
- Iannone I
- Ibrahim Y
- Ikram S
- Ilozue T
- Imperatore M
- Inama M
- Inama M
- Infante H
- Iosif E
- Iqbal Mr
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- Irukulla S
- Irwin R
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- Islam N
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- Ivey P
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- Julià D
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- Keegan R
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- Kirkham En
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- Kouroumpas E
- Krishnamoorthy A
- Krivan S
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- Ladwa N
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- Lorettu A
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- Ly C
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- Maderuelo Vm
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- Malik Y
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- Maqboul F
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- Marangoni G
- Marano A
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- Maretto I
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- Mcilwrath Ac
- Mcintyre R
- Mckay Sc
- Mckelvie Ma
- Mckenna M
- Mckeon J
- Mckevitt Kl
- Mckinley Nc
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- Mcmahon Sv
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- Mcnally L
- Mcquaid M
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- Medina-Arana V
- Mehigan B
- Melis A
- Melis M
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- Menzies D
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- Merichal-Resina M
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- Moroni P
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- Morrison F
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- Morrison-Jones V
- Morton Dg
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- Motiwala Fh
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- Mowbray Ng
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- Mozo As
- Mughal Z
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- Neale A
- Neary Pm
- Nehikhare I
- Nelli T
- Neophytou Gi
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- Newton Rc
- Newton Rc
- Ng J
- Ng M
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- Nickson S
- Nicol D
- Nicolosi A
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- O'Hagan Sc
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- O'Neill E
- O'Neill M
- O'Neill N
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- Oakey M
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- Occhioni G
- Odeh A
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- Ogbuokiri C
- Ojea-Ruiz-Yherla L
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- Okorocha E
- Olagbaiye O
- Oliva I
- Olivares-Oliver C
- Oliver Jr
- Olivier Jb
- Olivier Jb
- Olmos V
- Ooi R
- Orawiec P
- Orizu M
- Orizu M
- Orlando G
- Orme N
- Ormiston R
- Ormiston R
- Osterberg A
- Padilla E
- Padilla-Valverde D
- Paget C
- Pais M
- Pala M
- Palani-Velu Lk
- Palani-Velu Lk
- Pan Y
- Panagiotopoulos Sp
- Panda N
- Panda N
- Panda N
- Pandey V
- Pandya D
- Pandya R
- Paniagua M
- Pankin Gp
- Papandrea M
- Parajó Ae
- Paramasevon Kr
- Pareja-Ciuró F
- Parisi A
- Park Jh
- Park Jh
- Parkola Mj
- Parra Jm
- Parwaiz I
- Pascua-Sole M
- Pascual-Miguelañez I
- Pasquali S
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F
- Pata F.
- Pata G
- Pata G
- Pata G
- Patel As
- Patel By
- Patel By
- Patel C
- Patel H
- Patel Mm
- Patel N
- Patel Pk
- Patel Rt
- Patil Sd
- Patti S
- Pau R
- Payne Cj
- Payne Re
- Payá-Llorente C
- Payá-Llorente C
- Peacock M
- Pearce J
- Pearce J
- Pearce L
- Pearce L
- Pearson R
- Pedder A
- Peirce Cb
- Peiris Gb
- Peixoto R
- Peleki A
- Peleki A
- Pellegrino L
- Pellicanò Ga
- Pellicer-Franco E
- Pellino G
- Pento V
- Pento V
- Peponis C
- Peprah D
- Pereira A
- Pereira Am
- Pereira J
- Pereira-Mosquera E
- Perera Mi
- Perez-Calvo J
- Perin A
- Pertile D
- Pertile D
- Peña-Barturen C
- Phelan L
- Photiou D
- Pierre R
- Pietrabissa A
- Pigem A
- Pila U
- Pilkington Jp
- Pineño-Flores C
- Pinillos-Somalo A
- Pinkney Td
- Pinkney Td
- Pinkney Td
- Pinna E
- Pino-Perez O
- Pirari Pf
- Pisanu A
- Piu F
- Planellas P
- Plua-Muniz Kt
- Poacher A
- Podda F
- Podda M
- Podda M
- Podda M
- Poillucci G
- Pollard H
- Ponchietti L
- Popova D
- Poudevigne M
- Prats Ma
- Prideaux A
- Prieto-Nieto Mi
- Primo Jc
- Pronin S
- Provenza G
- Puerta E
- Pulighe F
- Pullabatla-Venkata Up
- Punj S
- Pérez-Sanchez Le
- Quddus A
- Quill S
- Quinn Em
- Quinn Hc
- Rabie M
- Rabie Ma
- Rabie Mr
- Radwan Rw
- Radwan Rw
- Rahim A
- Rahman M
- Rahmani Ls
- Rajagopal S
- Rajaram R
- Rajaretnam N
- Rajjoub Y
- Rallage H
- Ramcharan S
- Ramirez L
- Ramirez-Redondo Aa
- Ramos Xh
- Ramos-Bernado Mi
- Ramírez-Faraco M
- Ranathunga S
- Rangarajan K
- Rao M
- Rao V
- Raofi A
- Rashid M
- Rate A
- Ravindran R
- Raymond M
- Raza Ss
- Recreo Ac
- Reddy A
- Reddy A
- Redmond Ae
- Redondo E
- Redondo E
- Redondo-Calvo Fj
- Reese G
- Regina G
- Rehman S
- Rehman S
- Rekhraj S
- Ren Kz
- Renshaw S
- Renshaw S
- Renzi Cr
- Resende Fm
- Rezacova M
- Rezvani S
- Riaz W
- Riba-Combatti L
- Ribaudo M
- Ribeiro B
- Rich Je
- Richardson Td
- Ridaura N
- Riera E
- Rigby S
- Rigney B
- Rinkoff S
- Ripoli Mc
- Robb Hd
- Robertson C
- Robinson A
- Robinson A
- Robinson D
- Robinson D
- Rocha R
- Rodger V
- Rodicio-Miravalles Jl
- Rodriguez L
- Rodriguez-Lopez M
- Rodriguez-Lopez M
- Rodriguez-Lopez M
- Rodríguez Ec
- Rojo Ja
- Roldán-Ortiz S
- Rolph R
- Romano J
- Romano R
- Romario Uf
- Romoli L
- Roncero Ls
- Ronda Rn
- Roomi S
- Rosa Mj
- Rosat A
- Roscio F
- Roscio F
- Roscio F
- Rossi C
- Rossi D
- Rossi Gm
- Roth N
- Rothnie K
- Roxburgh C
- Roy C
- Ruano A
- Rubbini M
- Rudland I
- Ruffolo C
- Rufo E
- Ruggiu Gv
- Ruiz-Marín M
- Ruiz-Marín M
- Rupani S
- Rupasinghe Sn
- Rupasinghe Sn
- Rutherford Dg
- Ruzvidzo F
- Ruzzenente A
- Saad M
- Saad M
- Saavedra-Chacón M
- Saba A
- Sabia D
- Sacco R
- Sacks R
- Sadek S
- Saghir N
- Sagnotta A
- Sagnotta A
- Saha A
- Sahay Sj
- Sahnan K
- Sahnan K
- Sainz B
- Sainz B
- Sajid Ms
- Salama Y
- Salamone G
- Salamone G
- Salamone G
- Salamone G
- Salandini Mc
- Salem A
- Salim S
- Salva Ab
- Salvador H
- Samartin C
- Sammarco G
- Sammarco G
- Samuel M
- Sana S
- Sanchez Er
- Sanchez Er
- Sanchez L
- Sanchez-Garcia S
- Sanchez-Guillen L
- Sanchez-Guillen L
- Sanchez-Martinez A
- Sancho-Muriel J
- Sandu L
- Sanna S
- Santamaria C
- Santamaría Pc
- Santarrufina-Martínez S
- Santos Sc
- Santurro L
- Sanz-Navarro S
- Sarmah P
- Sarmah P
- Sarmah P
- Sarveswaran J
- Sasia D
- Sasia D
- Saunders S
- Savill A
- Savino G
- Savino G
- Savioli F
- Scabini S
- Scabini S
- Scabini S
- Scandroglio Is
- Scanlon K
- Scatizzi M
- Scialandrone G
- Scricciolo M
- Sebastian Jf
- Sebastián-Tomás Jc
- Seddon Tc
- Segalini E
- Segura-Sampedro Jj
- Sena G
- Sena-Ruiz F
- Seneviratne N
- Sepe C
- Serventi F
- Serventi F
- Seth M
- Setshwaelo T
- Sezen E
- Sgardelis P
- Sgrò A
- Sgrò A
- Sgrò A
- Shah J
- Shah K
- Shah Sm
- Shah Sm
- Shaikh Ia
- Shakoor Z
- Shanmuganathan V
- Shanmugarajah K
- Sharma A
- Sharma A
- Sharma P
- Sharp Ol
- Sharp Ol
- Shaw Av
- Shepherd Ja
- Sherif Ma
- Shet S
- Shetty Vd
- Shingler G
- Shiwani Mh
- Shrestha D
- Shurlock J
- Sian T
- Siaw O
- Siddique K
- Siddiqui Mn
- Siddiqui Za
- Sierra-Grañón Je
- Siggens Kl
- Sihra N
- Silva A
- Silva I
- Silvestri V
- Simioni A
- Simmonds L
- Simmonds L
- Simo V
- Simoes J
- Simpson Dj
- Singh A
- Singh J
- Singh P
- Singh S
- Singhal T
- Singhal T
- Sivaloganathan P
- Skalamera I
- Skerritt C
- Slezak I
- Smallcombe N
- Smart Cj
- Smart Cj
- Smart Nj
- Smart Nj
- Smoker H
- Soares A. S.
- Soares As
- Soares As
- Soares As
- Soares As
- Soares As
- Soh B
- Solaini L
- Solar-García L
- Soliani P
- Solinas L
- Sooriyamoorthy T
- Soria-Aledo V
- Soria-Aledo V
- Soriano Jt
- Sorrentino L
- Sousa Hs
- Souter J
- Sparta C
- Spaziani A
- Speake D
- Speake D
- Springate El
- Sreedharan L
- Sreedharan L
- Staderini F
- Stecca T
- Stella M
- Stephens Gf
- Stephens Gf
- Stevenson R
- Stewart Dj
- Stoica I
- Storey R
- Stoyanov Ti
- Strachan E
- Strange Ja
- Stubbs Bm
- Stupalkowska W
- Stupalkowska W
- Suarez-Cabrera A
- Suero Ca
- Sultana A
- Summerfield L
- Sunter H
- Surg Pt
- Suriyakumar S
- Suárez-Sánchez A
- Swords C
- Symons N
- Szentpali K
- Szucs A
- Szucs A
- Sánchez-Cifuentes A
- Sánchez-Fuentes Mn
- Sánchez-Rubio M
- Tabain V
- Taglietti L
- Tague Le
- Tahir W
- Tailor K
- Tallon-Aguilar L
- Tallon-Aguilar L
- Tamayo-López Mj
- Tamborska A
- Tamini N
- Tamini N
- Tamini N
- Tan Cy
- Tan Cy
- Tan E
- Tan Hl
- Tan S
- Tang Am
- Tapiolas I
- Tarazi M
- Tatulli F
- Tay Yh
- Tayeh S
- Taylor M
- Taylor Ns
- Taylor Ns
- Taze D
- Tee A
- Tejero-Pintor Fj
- Tenconi Sm
- Tezas S
- Thaha Ma
- Thakral N
- Thakur D
- Thava B
- Thavanesan N
- Thavanesan N
- Thaventhiran Aj
- Theodoropoulou K
- Thomas At
- Thomas L
- Thompson C
- Thompson Db
- Thompson Db
- Thompson R
- Thompson R
- Thoukididou Sn
- Tiedt La
- Tiedt La
- Ting N
- Tinoco-González J
- Tinsley Bj
- Tognarelli Jm
- Tojal A
- Tokidis E
- Tomasoni M
- Tonini V
- Toomey D
- Toomey Db
- Torkington J
- Torkington J
- Torrado Aa
- Torrance A
- Torrance A
- Townsend Dc
- Townsend Dc
- Tozer Pj
- Trail M
- Trail M
- Trastulli S
- Trew F
- Trostchansky I
- Trujillo-Diaz Jj
- Tsang B
- Tudyka V
- Tudyka V
- Turnbull A
- Turner Ej
- Tutino R
- Twum-Barima Cs
- Twum-Barima Cs
- Tyler R
- Tyler R
- Ugarte-Sierra B
- Vacca A
- Vaccari S
- Vakis S
- Valente Pm
- Valiani Sv
- Vallejo-Bernad C
- Vallve-Bernal M
- Van Boxel Gi
- Vance-Daniel J
- Vannucchi A
- Varcada M
- Vargas-Pierola Hj
- Vaughan Em
- Vaughan Em
- Vazquez-Fernandez Ap
- Vega L
- Velchuru Vr
- Velho R
- Venkata Up
- Venkatasubramaniam Ak
- Venn Ml
- Venn Ml
- Venugopal R
- Verea S
- Veres T
- Veres T
- Verroiotou M
- Vescio G
- Vettoretto N
- Vigorita V
- Vijay V
- Vila-Zarate C
- Villarejo-Campos P
- Vinnicombe Z
- Viscosi F
- Vitish-Sharma P
- Viviani E
- Viñas Nl
- Vohra R
- Vohra R
- Vulcano I
- Waite K
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- Wauchope J
- Weatherburn Lw
- Weaver J
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- Wensley F
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- Wong Sy
- Woo R
- Wood Cs
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- Woodward A
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- Wright E
- Wright Hl
- Wu F
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- Yalamarthi S
- Yang P
- Yanni F
- Yardimci E
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- Yen Sk
- Yeung K
- Yeung K
- Yoganathan S
- Yoong S
- Youssef H
- Yow L
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- Zalla T
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- Zelazek M
- Zerpa C
- Zhang Ay
- Zhou S
- Zorrilla L
- Zuin M
- Zurleni Tz
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Background
Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.
Methods
A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).
Results
Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).
Conclusion
Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified
Absolute parameters for AI Phoenicis using WASP photometry (vol 591, A124, 2016) (Erratum)
- Publication venue
- 'EDP Sciences'
- Publication date
- 17/12/2018
- Field of study
Erratum to: A&A 591, A124 (2016), https://doi.org/10.1051/0004-6361/20162858
Recommended from our members
Validation of the Scientific Program for the Dark Energy Spectroscopic Instrument
- Author
- A Gontcho S Gontcho
- Adame AG
- Aguilar J
- Ahlen S
- Alam S
- Aldering G
- Alexander DM
- Alfarsy R
- Allende Prieto C
- Alvarez M
- Alves O
- Anand A
- Andrade-Oliveira F
- Armengaud E
- Asorey J
- Avila S
- Aviles A
- Bailey S
- Balaguera-Antolínez A
- Ballester O
- Baltay C
- Bault A
- Bautista J
- Behera J
- Beltran SF
- BenZvi S
- Beraldo e Silva L
- Bermejo-Climent JR
- Berti A
- Besuner R
- Beutler F
- Bianchi D
- Blake C
- Blum R
- Bolton AS
- Brieden S
- Brodzeller A
- Brooks D
- Brown Z
- Buckley-Geer E
- Burtin E
- Cabayol-Garcia L
- Cai Z
- Canning R
- Cardiel-Sas L
- Carnero Rosell A
- Castander FJ
- Cervantes-Cota JL
- Chabanier S
- Chaussidon E
- Chaves-Montero J
- Chen S
- Chen X
- Chuang C
- Claybaugh T
- Cole S
- Cooper AP
- Cuceu A
- Davis TM
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- de Belsunce R
- de la Cruz R
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- de Mattia A
- Demina R
- Demirbozan U
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- Ding J
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- Doshi R
- Douglass K
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- Eftekharzadeh S
- Eisenstein DJ
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- Ereza J
- Escoffier S
- Fagrelius P
- Fan X
- Fanning K
- Fawcett VA
- Ferraro S
- Flaugher B
- Font-Ribera A
- Forero-Romero JE
- Forero-Sánchez D
- Frenk CS
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- Juneau S
- Karaçaylı NG
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- Kehoe R
- Kent S
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- Kirkby D
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- Kitaura F
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- Meneses-Rizo J
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- Weaverdyck N
- Wechsler RH
- White M
- Xie Y
- Yang J
- Yu J
- Yuan S
- Yèche C
- Zhang H
- Zhang Z
- Zhao C
- Zheng Z
- Zhiwei P
- Zhou R
- Zhou Z
- Zou H
- Zou S
- Zu Y
- Publication venue
- The Astronomical Journal
- Publication date
- 15/01/2024
- Field of study
Abstract
The Dark Energy Spectroscopic Instrument (DESI) was designed to conduct a survey covering 14,000 deg2 over 5 yr to constrain the cosmic expansion history through precise measurements of baryon acoustic oscillations (BAO). The scientific program for DESI was evaluated during a 5 month survey validation (SV) campaign before beginning full operations. This program produced deep spectra of tens of thousands of objects from each of the stellar Milky Way Survey (MWS), Bright Galaxy Survey (BGS), luminous red galaxy (LRG), emission line galaxy (ELG), and quasar target classes. These SV spectra were used to optimize redshift distributions, characterize exposure times, determine calibration procedures, and assess observational overheads for the 5 yr program. In this paper, we present the final target selection algorithms, redshift distributions, and projected cosmology constraints resulting from those studies. We also present a One-Percent Survey conducted at the conclusion of SV covering 140 deg2 using the final target selection algorithms with exposures of a depth typical of the main survey. The SV indicates that DESI will be able to complete the full 14,000 deg2 program with spectroscopically confirmed targets from the MWS, BGS, LRG, ELG, and quasar programs with total sample sizes of 7.2, 13.8, 7.46, 15.7, and 2.87 million, respectively. These samples will allow exploration of the Milky Way halo, clustering on all scales, and BAO measurements with a statistical precision of 0.28% over the redshift interval z < 1.1, 0.39% over the redshift interval 1.1 < z < 1.9, and 0.46% over the redshift interval 1.9 < z < 3.5.</jats:p
Recommended from our members
Validation of the Scientific Program for the Dark Energy Spectroscopic Instrument
- Author
- A Gontcho S Gontcho
- Adame AG
- Aguilar J
- Ahlen S
- Alam S
- Aldering G
- Alexander DM
- Alfarsy R
- Allende Prieto C
- Alvarez M
- Alves O
- Anand A
- Andrade-Oliveira F
- Armengaud E
- Asorey J
- Avila S
- Aviles A
- Bailey S
- Balaguera-Antolínez A
- Ballester O
- Baltay C
- Bault A
- Bautista J
- Behera J
- Beltran SF
- BenZvi S
- Beraldo e Silva L
- Bermejo-Climent JR
- Berti A
- Besuner R
- Beutler F
- Bianchi D
- Blake C
- Blum R
- Bolton AS
- Brieden S
- Brodzeller A
- Brooks D
- Brown Z
- Buckley-Geer E
- Burtin E
- Cabayol-Garcia L
- Cai Z
- Canning R
- Cardiel-Sas L
- Carnero Rosell A
- Castander FJ
- Cervantes-Cota JL
- Chabanier S
- Chaussidon E
- Chaves-Montero J
- Chen S
- Chen X
- Chuang C
- Claybaugh T
- Cole S
- Cooper AP
- Cuceu A
- Davis TM
- Dawson K
- de Belsunce R
- de la Cruz R
- de la Macorra A
- de Mattia A
- Demina R
- Demirbozan U
- DeRose J
- Dey A
- Dey B
- Dhungana G
- Ding J
- Ding Z
- Doel P
- Doshi R
- Douglass K
- Edge A
- Eftekharzadeh S
- Eisenstein DJ
- Elliott A
- Ereza J
- Escoffier S
- Fagrelius P
- Fan X
- Fanning K
- Fawcett VA
- Ferraro S
- Flaugher B
- Font-Ribera A
- Forero-Romero JE
- Forero-Sánchez D
- Frenk CS
- Garcia-Quintero C
- García LÁ
- García-Bellido J
- Garrison LH
- Gil-Marín H
- Golden-Marx J
- Gonzalez-Morales AX
- Gonzalez-Perez V
- Gordon C
- Graur O
- Green D
- Gruen D
- Guy J
- Gänsicke BT
- Hadzhiyska B
- Hahn C
- Han JJ
- Hanif MMS
- Herrera-Alcantar HK
- Honscheid K
- Hou J
- Howlett C
- Huterer D
- Iršič V
- Ishak M
- Jana A
- Jiang L
- Jimenez J
- Jing YP
- Joudaki S
- Joyce R
- Jullo E
- Juneau S
- Karaçaylı NG
- Karim T
- Kehoe R
- Kent S
- Khederlarian A
- Kim S
- Kirkby D
- Kisner T
- Kitaura F
- Kizhuprakkat N
- Kneib J
- Koposov SE
- Kovács A
- Kremin A
- Krolewski A
- Lahav O
- Lambert A
- Lamman C
- Lan T-W
- Landriau M
- Lang D
- Lange JU
- Lasker J
- Le Guillou L
- Leauthaud A
- Levi ME
- Li TS
- Linder E
- Lyons A
- L’Huillier B
- Magneville C
- Manera M
- Manser CJ
- Margala D
- Martini P
- McDonald P
- Medina GE
- Medina-Varela L
- Meisner A
- Mena-Fernández J
- Meneses-Rizo J
- Mezcua M
- Miquel R
- Montero-Camacho P
- Moon J
- Moore S
- Moustakas J
- Mueller E
- Mundet J
- Muñoz-Gutiérrez A
- Myers AD
- Nadathur S
- Napolitano L
- Neveux R
- Newman JA
- Nie J
- Niz G
- Norberg P
- Noriega HE
- Paillas E
- Palanque-Delabrouille N
- Palmese A
- Parkinson D
- Penmetsa S
- Percival WJ
- Pieri M
- Poppett C
- Porredon A
- Prada F
- Pucha R
- Pérez-Fernández A
- Pérez-Ràfols I
- Raichoor A
- Ramirez-Solano S
- Ramírez-Pérez C
- Rashkovetskyi M
- Ravoux C
- Rocher A
- Rockosi C
- Ross AJ
- Rossi G
- Ruggeri R
- Ruhlmann-Kleider V
- Sabiu CG
- Said K
- Saintonge A
- Samushia L
- Sanchez E
- Saulder C
- Schaan E
- Schlafly EF
- Schlegel D
- Scholte D
- Schubnell M
- Seo H
- Shafieloo A
- Sharples R
- Sheu W
- Silber J
- Sinigaglia F
- Siudek M
- Slepian Z
- Smith A
- Sprayberry D
- Stephey L
- Sun Z
- Suárez-Pérez J
- Tan T
- Tarlé G
- Tojeiro R
- Ureña-López LA
- Vaisakh R
- Valcin D
- Valdes F
- Valluri M
- Vargas-Magaña M
- Variu A
- Verde L
- Walther M
- Wang B
- Wang MS
- Weaver BA
- Weaverdyck N
- Wechsler RH
- White M
- Xie Y
- Yang J
- Yu J
- Yuan S
- Yèche C
- Zhang H
- Zhang Z
- Zhao C
- Zheng Z
- Zhiwei P
- Zhou R
- Zhou Z
- Zou H
- Zou S
- Zu Y
- Publication venue
- The Astronomical Journal
- Publication date
- 22/01/2024
- Field of study
Abstract
The Dark Energy Spectroscopic Instrument (DESI) was designed to conduct a survey covering 14,000 deg2 over 5 yr to constrain the cosmic expansion history through precise measurements of baryon acoustic oscillations (BAO). The scientific program for DESI was evaluated during a 5 month survey validation (SV) campaign before beginning full operations. This program produced deep spectra of tens of thousands of objects from each of the stellar Milky Way Survey (MWS), Bright Galaxy Survey (BGS), luminous red galaxy (LRG), emission line galaxy (ELG), and quasar target classes. These SV spectra were used to optimize redshift distributions, characterize exposure times, determine calibration procedures, and assess observational overheads for the 5 yr program. In this paper, we present the final target selection algorithms, redshift distributions, and projected cosmology constraints resulting from those studies. We also present a One-Percent Survey conducted at the conclusion of SV covering 140 deg2 using the final target selection algorithms with exposures of a depth typical of the main survey. The SV indicates that DESI will be able to complete the full 14,000 deg2 program with spectroscopically confirmed targets from the MWS, BGS, LRG, ELG, and quasar programs with total sample sizes of 7.2, 13.8, 7.46, 15.7, and 2.87 million, respectively. These samples will allow exploration of the Milky Way halo, clustering on all scales, and BAO measurements with a statistical precision of 0.28% over the redshift interval z < 1.1, 0.39% over the redshift interval 1.1 < z < 1.9, and 0.46% over the redshift interval 1.9 < z < 3.5.</jats:p
Weighing stars from birth to death: mass determination methods across the HRD
- Author
- A Bressan
- A Chontos
- A Claret
- A Drazdauskas
- A Escorza
- A Escorza
- A Frebel
- A Gallenne
- A Gallenne
- A Gianninas
- A Herrero
- A Maeder
- A Moya
- A Serenelli
- A Sollima
- A Sozzetti
- A Stokholm
- A Tkachenko
- A Tkachenko
- A Tkachenko
- A Tkachenko
- A Tkachenko
- A Udalski
- A Weiss
- A Zurlo
- AC Sippel
- ACS Jørgensen
- AD Romero
- AD Romero
- AF Marino
- AH Córsico
- AH Córsico
- AK Dupree
- AK Dupree
- AL Kraus
- AM Serenelli
- AN Cox
- AP Milone
- AP Milone
- AS Eddington
- AW Mann
- AYQ Ho
- B Burnett
- B Campbell
- B Davies
- B Giesers
- B Kimmig
- B Macintosh
- B Mennesson
- B Nsamba
- B Nsamba
- B Paxton
- BF Lane
- BM Rendle
- BR Jørgensen
- C Aerts
- C Aerts
- C Aerts
- C Aerts
- C Aerts
- C Charbonnel
- C Chiosi
- C Genest-Beaulieu
- C Johnston
- C Johnston
- C Liu
- C Marois
- C Weidner
- CA Hummel
- CA Hummel
- CA Hummel
- CA Hummel
- CAL Bailer-Jones
- CHS Lacy
- CL Sahlholdt
- CL Sahlholdt
- CS Rosenthal
- D Foreman-Mackey
- D Gandolfi
- D Graczyk
- D Graczyk
- D Huber
- D Jones
- D Koester
- D Lorenzo-Oliveira
- D Stello
- D Stello
- DB Guenther
- DE Winget
- DG Koch
- DH Ferguson
- DJ Mullan
- DK Feuillet
- DM Bowman
- DM Bowman
- DR Reese
- DR Xiong
- DW Kurtz
- DW Kurtz
- DW Latham
- E Aubourg
- E Brandi
- E Carretta
- E Carretta
- E Corsaro
- E Corsaro
- E Cukanovaite
- E Gallo
- E García-Berro
- E Gillen
- E Hertzsprung
- E Jofré
- E Moravveji
- E Semenova
- E Tolstoy
- EJ Farrell
- EL Martín
- EP Bellinger
- EP Bellinger
- ER Beasor
- EV Garcia
- F Grundahl
- F Martins
- F Martins
- F Niederhofer
- F Pepe
- F Pont
- F Thévenin
- F Özel
- FA Bastien
- FA Bastien
- FC Fekel
- FC Fekel
- FRN Schneider
- FRN Schneider
- FRN Schneider
- FW Dyson
- G Buldgen
- G Buldgen
- G Chabrier
- G Coppola
- G Costa
- G Fontaine
- G Fontaine
- G Handler
- G Li
- G Meylan
- G Michaud
- G Pietrzyński
- G Pietrzyński
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- G Takeda
- G Tinetti
- G Torres
- G Torres
- G Torres
- G Torres
- G Torres
- G Torres
- G Wagstaff
- G Windmiller
- G Zhou
- GA Feiden
- GC Angelou
- GC Angelou
- GC Angelou
- GH Schaefer
- GR Davies
- GR Ricker
- GS Da Costa
- GW Marcy
- H Hensberge
- H Otí Floranes
- H Sana
- H Schild
- HC Spruit
- HE Bond
- HE Bond
- HE Bond
- HE Bond
- HE Bond
- HN Russell
- HP Osborn
- HR Coelho
- HR Neilson
- HR Neilson
- HW Leung
- I Baraffe
- I Baraffe
- I Czekala
- I Czekala
- I Czekala
- I Czekala
- I González-Santamaría
- I González-Santamaría
- I Ribas
- IW Roxburgh
- J Andersen
- J Antoniadis
- J Bagnuolo
- J Casares
- J Choi
- J Christensen-Dalsgaard
- J Christensen-Dalsgaard
- J De Ridder
- J Higl
- J Irwin
- J Lin
- J MacDonald
- J Prieto-Arranz
- J Southworth
- J Southworth
- J Southworth
- J Southworth
- J Strader
- J Tayar
- J Tonry
- JA Cardelli
- JA Carter
- JA Dittmann
- JA Guzik
- JA Kirkby-Kent
- JA Kirkby-Kent
- JC Mermilliod
- JC Morales
- JC Morales
- JC Morales
- JC van Eyken
- JC Zinn
- JD Cummings
- JD Hartman
- JE Gunn
- JF Donati
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- JJ Hermes
- JJD Do Nascimento
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- JN Bahcall
- JS Kalirai
- JSG Mombarg
- JSG Mombarg
- JT Mackereth
- JTL Duvall
- JW Lee
- JW Xie
- K Belkacem
- K Brogaard
- K El-Badry
- K Fricke
- K Kremer
- K Liu
- K Pavlovski
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- K Verma
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- KA Kretke
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- KG Stassun
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- KG Stassun
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- KM Exter
- KP Schröder
- KP Simon
- L Bugnet
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- L Chomiuk
- L da Silva
- L Fossati
- L Ghezzi
- L Hendriks
- L Mahy
- L Mahy
- L Szigeti
- LG Althaus
- LG Althaus
- LR Doyle
- M Afşar
- M Aizenman
- M Asplund
- M Asplund
- M Auvergne
- M Bazot
- M Bazot
- M Bergemann
- M Carlos
- M Carlos
- M Castro
- M Deal
- M Deleuil
- M Gieles
- M Giersz
- M Gruberbauer
- M Konacki
- M Konacki
- M López-Morales
- M Martig
- M Mayor
- M Michielsen
- M Ness
- M Ortiz
- M Rozyczka
- M Salaris
- M Salaris
- M Salaris
- M Santander-García
- M Schofield
- M Shetrone
- M Simon
- M Simon
- M Vučković
- MAT Groenewegen
- MG Pedersen
- MG Pedersen
- MG Pedersen
- MH Pinsonneault
- MJ Pecaut
- ML Rawls
- MM Miller Bertolami
- MN Lund
- MR Mokiem
- MS Cunha
- MS Cunha
- MW Muterspaugh
- N Bastian
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- N Bastian
- N Castro
- N Giammichele
- N Grevesse
- N Langer
- N Lodieu
- N Reindl
- N Themeßl
- N Yusof
- NEQ Paust
- NP Gentile Fusillo
- O De Marco
- OJ Hall
- OY Malkov
- P Bergeron
- P Das
- P Degroote
- P Delorme
- P Demarque
- P Eggenberger
- P Gaulme
- P Hadrava
- P Jofré
- P Jofré
- P Kervella
- P Marigo
- PA Cargile
- PE Tremblay
- PE Tremblay
- PE Tremblay
- PE Tremblay
- PFL Maxted
- PFL Maxted
- PG Beck
- PG Beck
- PG Beck
- PG Breen
- PI Pápics
- PP Eggleton
- R Gafeira
- R Handberg
- R Martínez-Arnáiz
- R Schönrich
- RA García
- RA Wade
- RD Blandford
- RE Wilson
- RF Christy
- RG Athay
- RG Gratton
- RH Østensen
- RHD Townsend
- RJ Rutten
- RJ Siverd
- RJ Stancliffe
- RM Ouazzani
- RP Grabhorn
- RP Schiavon
- RS Stobie
- RW Hilditch
- RW Hilditch
- S Basu
- S Basu
- S Burssens
- S Cassisi
- S Catalán
- S Deheuvels
- S Deheuvels
- S Deheuvels
- S Frandsen
- S Gossage
- S Guilloteau
- S Hasselquist
- S Hekker
- S Hekker
- S Kamann
- S Migliari
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- S Xu
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- SB Howell
- SG Parsons
- SJ Smartt
- SL Martell
- SM Andrews
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- SM Simkin
- SP Malla
- SRG Joyce
- SS Larsen
- SS Larsen
- T Appourchaux
- T Gardner
- T Kallinger
- T Kallinger
- T Kallinger
- T Masseron
- T Masseron
- T Sonoi
- T Sukhbold
- T Van Reeth
- T Van Reeth
- T Van Reeth
- TC Hillwig
- TJ David
- TJ David
- TJL de Boer
- TJL de Boer
- TL Campante
- TM Rogers
- TR White
- TR White
- TS Metcalfe
- TS Metcalfe
- TS Rodrigues
- TS Rodrigues
- TSH North
- TY Steiman-Cameron
- U Heber
- V Burkholder
- V Fragkou
- V Fragkou
- V Hénault-Brunet
- V Schaffenroth
- V Silva Aguirre
- V Silva Aguirre
- V Van Eylen
- V Van Eylen
- V Van Eylen
- V Weidemann
- W Szewczuk
- WF Welsh
- WH Ball
- WJ Borucki
- WJ Chaplin
- WJ Chaplin
- WJ Chaplin
- WW Weiss
- X Delfosse
- Y Gómez Maqueo Chew
- Y Lebreton
- Y Lebreton
- Y Wu
- Z Eker
- Z Eker
- Z Shkedy
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Management of the Hypertensive Child
- Author
- A Calzolari
- A DiPietro
- A Fiebeler
- A Grimsrud
- A Mahmud
- A Mehta
- A Mimran
- A Nickavar
- A Parashar
- A Pelliccia
- A Rossi
- AB Alper Jr
- AB Fogo
- AB Kramer
- AB Zubrow
- ABR Maggio
- AC Tissot
- AC Truttmann
- AD Struthers
- AE Caballero
- AJ Claxton
- AK Bidani
- AK Gupta
- AL Kent
- AM Bender
- AM Zivkovic
- American Diabetes Association
- AP Rocchini
- AP Traon
- AR Alqahtani
- AR Sinaiko
- AS Brem
- AV Chobanian
- B Carlberg
- B Dahlof
- B Engelhardt
- B Falkner
- B Falkner
- B Falkner
- B Oneda
- B Rodriguez-Iturbe
- B Sibai
- B Soffer
- B Torrance
- BC Rossier
- BD LaMarca
- BM Brenner
- BM Brenner
- BM Brenner
- BP Marriott
- C Feldstein
- C Gennaro Di
- C Gimpel
- C Hadtstein
- C Hanevold
- C Monder
- C Yallampalli
- CA Thomas
- CA Thomas
- CD Boyle
- CD Pereira
- CE Johnson
- CJ Reissig
- CL Ogden
- CL Ogden
- CM Brown
- CM Cheung
- CM Nzerue
- Committee on Nutrition and the Council on Sports Medicine and Fitness
- CS Kase
- CS Wiysonge
- CW Belsha
- D Cherney
- D Ellis
- D Ellis
- D Ellis
- D McAreavey
- D Singh
- D Zeeuw de
- DA Calhoun
- DA Sica
- DA Sica
- DA Sica
- DB Wiest
- DI Feig
- DI Feig
- DI Feig
- DL Batisky
- DL Bhatt
- DM Silverstein
- DM Silverstein
- DM Silverstein
- DS Celermajer
- DS Geller
- DS Goldstein
- DS Kohane
- DS Wald
- DW Egger
- DW Matthews
- E Casiglia
- E Constantine
- E Lurbe
- E Lurbe
- E O’Brien
- E Pimenta
- E Ritz
- E Urbina
- E Wuhl
- EA Rosei
- ED Deeks
- EG Neilson
- EJ Lewis
- EM Freel
- ES Ford
- F Barbe
- F Lobelo
- F Mantero
- F Sofi
- FC Luft
- FC Luft
- FD McBryde
- FH Messerli
- FM Sacks
- FM Sacks
- G Bakris
- G Bobrie
- G Evoniuk
- G Grassi
- G Grassi
- G Guron
- G Keller
- G Mancia
- G Mancia
- G Mancia
- G Mancia
- G Mancia
- G Mancia
- G Mancia
- G Mancia
- G Morineau
- G Parati
- G Wolf
- GA Bray
- GA Mansoor
- GA Mansoor
- GA Pincomb
- GB Hammer
- GD Simonetti
- GD Simonetti
- GL Bakris
- GL Bakris
- GL Bakris
- H Gavras
- H Krum
- H Masuzaki
- H Sun
- H Wang
- H Yoshida
- HE Abboud
- HH Parving
- HH Parving
- HJ Adrogue
- HO Dickinson
- HP Patel
- HR Toka
- HT Hulsen
- IB Puddey
- J Fessel
- J He
- J Lea
- J Oliver
- J Samuels
- J Turmel
- JA Berman
- JA Blumenthal
- JA Cutler
- JA Oliver
- JB Gouyon
- JB Kostis
- JC Xu
- JD Bisognano
- JD Rosario Del
- JD Tobias
- JE Hall
- JE Hall
- JE Hall
- JE Hollander
- JE Liu
- JE Neter
- JE Sullivan
- JF Mann
- JH Mitchell
- JJ Leddy
- JK Healy
- JL MacDonald
- JL Tanji
- JM Dionne
- JM Flack
- JM Geleijnse
- JM Hagberg
- JM Roberts
- JM Sorof
- JM Sorof
- JM Sorof
- JM Sorof
- JM Sorof
- JM Sorof
- JP Bantle
- JR Treadwell
- JS Gilbert
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JT Flynn
- JW Graves
- K Chavanu
- K Gaddam
- K Heusser
- K Jamerson
- K Kilian
- K Narkiewicz
- K Pacak
- K Pacak
- K Rahmouni
- K Tullus
- KA Griffin
- KDIGO BP Work Group
- KF Buchi
- KG Parhofer
- KL Donnelly
- KL McNiece
- KM Barlow
- KO Yeates
- KP Conrad
- L Amar
- L Landsberg
- L Lozano
- L Osterberg
- L Patzer
- LD Johnston
- LD Johnston
- LG Navar
- LH Lindholm
- LJ Appel
- LJ Appel
- LJ Burton
- LJ Mullins
- LM Prisant
- LR Krakoff
- M Azizi
- M Azizi
- M Bochud
- M Burnier
- M Ehrhart-Bornstein
- M Litwin
- M Litwin
- M Marre
- M Mazzali
- M Mitsnefes
- M Molnar
- M Ruano
- MA Bailey
- MA Ferguson
- MA Weber
- MA Weber
- MB Vos
- MC Harter
- MD Esler
- ME Ernst
- MF Leitzmann
- MG Bianchetti
- MG Mohaupt
- MH Bonnet
- MH Fasting
- MI New
- MI New
- MI Phillips
- MJ Brown
- MJ Brown
- MJ Gregoski
- MJ Klag
- MJ Sarnak
- MM Mitsnefes
- MM Ng
- MM Ribeiro
- MN Eakin
- MP Castaneda
- MP Ponda
- MP Schlaich
- MR Carnethon
- MR Meyers
- MR Weir
- MR Wofford
- MU Nwankwo
- MW Kirkwood
- MY Arar
- N Dhaun
- N Dhaun
- N Rasouli
- N Sood
- NA Graudal
- NA Graudal
- National Heart Lung and Blood Institute
- National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents
- ND Vaziri
- NJ Farpour-Lambert
- NK Hollenberg
- NK Pollock
- NM Kaplan
- NR Cook
- NS Beckett
- NS Kirkby
- O Toka
- OP Wanne
- P Anagnostis
- P Bajracharya
- P Borusiak
- P Kampus
- P Zhao
- PA James
- PA Richey
- PE Marik
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GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
- Author
- Abdelrazik M
- Abedalthagafi M
- Abel L
- Abel L
- Abellan J
- Abernathy C
- Abraheem A
- Acklery A
- Acosta-Isaac R
- Adam R
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- Adams N
- Adanini O
- Afolabi D
- Agasou A
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- Agravante K
- Agrawal S
- Aguado JM
- Aguilar C
- Aguilar PM
- Aguilera-Albesa S
- Ahmad N
- Ahmadhaider N
- Ahmed A
- Ahmed C
- Aitkin E
- Akeroyd L
- Akhtar MN
- Akinkugbe O
- Al-Moasseb H
- Alasdair F
- Alba J
- Albu S
- Alcalá-Gallardo KAM
- Alcoba-Florez J
- Aldridge J
- Alex B
- Alexander P
- Alfonso J
- Algarin-Lara HR
- Ali A
- Ali HH
- Ali IAM
- Ali S
- Allan A
- Allan E
- Allan J
- Alldis Z
- Allen L
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- Allen S
- Allibone S
- Allison KS
- Ally SM
- Almadana V
- Almaden-Boyle C
- Almeida J
- Almoguera B
- Alonso MR
- Altabaibeh A
- Alvarez N
- Alvaro A
- Alves MDM
- Amamio M
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- Amin V
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- Anderson M
- Anderson P
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- Anderson S
- Anderson T
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- Andrew A
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- Antoine P
- Antonijoan MR
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- Anumakonda V
- Anwer M
- Apetri E
- Aquino M
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- Aranda C
- Arango C
- Araque C
- Araujo IMT
- Araujo NK
- Aravindan L
- Arbane G
- Arcanjo AC
- Archer K
- Arden T
- Arias SS
- Arif S
- Armistead J
- Armstrong D
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- Badal B
- Baddeley A
- Bafitis V
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- Bretherick AD
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- Cardwell A
- Carioca AAF
- Carmody M
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- Carpintero MS
- Carracedo A
- Carracedo A
- Carratto TMT
- Carrera LG
- Carrillo-Avila JA
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- Carter E
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- Castaño CF
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- Chiquillo-Gómez S
- Chisholm C
- Choudhr O
- Choudhury Y
- Chukkambotla S
- Chávez MEQ
- Cid-Lopez MA
- Cienfuegos-Jimenez O
- Cinquina Z
- Clamp S
- Clapham M
- Clarey E
- Claridge H
- Clark A
- Clark A
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- Clark R
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- Clement I
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- Clohisey S
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- Conejo IP
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- Conyngham J-A
- Cooke GS
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- Cordero-Lorenzana ML
- Corella D
- Corin C
- Cornell S
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- Corner A
- Corral MA
- Corrales A
- Cortes-Sanchez JL
- Corton M
- Cosgrove D
- Cosier T
- Costa TX
- Cother N
- Coton Z
- Cottam L-J
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- Coventry T
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- Cuerda VM
- Cuesta L
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- da Silva Filipe A
- da Silva GV
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- Dagutao Z
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- Daly Z
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- DAmato F
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- Dantas-Komatsu RCS
- Dark P
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- Darnaude MT
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- Day A
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- de Andrés R
- de Araújo JNG
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- de Bustamante AD
- de Gordoa LO-R
- de Heredia ML
- de Juan C
- De la Cruz Troca J
- de la Horra C
- de la Hoz AB
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- de Neef M
- De Queiroz JG
- de Quirós FGB
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- de Sousa Alves Neri JL
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- del Campo-Pérez V
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- García-García I
- García-Ibarbia C
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- Íñiguez M
- Publication venue
- Springer Nature
- Publication date
- 17/05/2023
- Field of study
Data availability: Downloadable summary data are available through the GenOMICC data site (https://genomicc.org/data). Summary statistics are available, but without the 23andMe summary statistics, except for the 10,000 most significant hits, for which full summary statistics are available. The full GWAS summary statistics for the 23andMe discovery dataset will be made available through 23andMe to qualified researchers under an agreement with 23andMe that protects the privacy of the 23andMe participants. For further information and to apply for access to the data, see the 23andMe website (https://research.23andMe.com/dataset-access/). All individual-level genotype and whole-genome sequencing data (for both academic and commercial uses) can be accessed through the UKRI/HDR UK Outbreak Data Analysis Platform (https://odap.ac.uk). A restricted dataset for a subset of GenOMICC participants is also available through the Genomics England data service. Monocyte RNA-seq data are available under the title ‘Monocyte gene expression data’ within the Oxford University Research Archives (https://doi.org/10.5287/ora-ko7q2nq66). Sequencing data will be made freely available to organizations and researchers to conduct research in accordance with the UK Policy Framework for Health and Social Care Research through a data access agreement. Sequencing data have been deposited at the European Genome–Phenome Archive (EGA), which is hosted by the EBI and the CRG, under accession number EGAS00001007111.Extended data figures and tables are available online at https://www.nature.com/articles/s41586-023-06034-3#Sec21 .Supplementary information is available online at https://www.nature.com/articles/s41586-023-06034-3#Sec22 .Code availability:
Code to calculate the imputation of P values on the basis of SNPs in linkage disequilibrium is available at GitHub (https://github.com/baillielab/GenOMICC_GWAS).Acknowledgements: We thank the members of the Banco Nacional de ADN and the GRA@CE cohort group; and the research participants and employees of 23andMe for making this work possible. A full list of contributors who have provided data that were collated in the HGI project, including previous iterations, is available online (https://www.covid19hg.org/acknowledgements).Change history: 11 July 2023: A Correction to this paper has been published at: https://doi.org/10.1038/s41586-023-06383-z. -- In the version of this article initially published, the name of Ana Margarita Baldión-Elorza, of the SCOURGE Consortium, appeared incorrectly (as Ana María Baldion) and has now been amended in the HTML and PDF versions of the article.Copyright © The Author(s) 2023, Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown1 to be highly efficient for discovery of genetic associations2. Despite the advanced stage of illness at presentation, we have shown that host genetics in patients who are critically ill with COVID-19 can identify immunomodulatory therapies with strong beneficial effects in this group3. Here we analyse 24,202 cases of COVID-19 with critical illness comprising a combination of microarray genotype and whole-genome sequencing data from cases of critical illness in the international GenOMICC (11,440 cases) study, combined with other studies recruiting hospitalized patients with a strong focus on severe and critical disease: ISARIC4C (676 cases) and the SCOURGE consortium (5,934 cases). To put these results in the context of existing work, we conduct a meta-analysis of the new GenOMICC genome-wide association study (GWAS) results with previously published data. We find 49 genome-wide significant associations, of which 16 have not been reported previously. To investigate the therapeutic implications of these findings, we infer the structural consequences of protein-coding variants, and combine our GWAS results with gene expression data using a monocyte transcriptome-wide association study (TWAS) model, as well as gene and protein expression using Mendelian randomization. We identify potentially druggable targets in multiple systems, including inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).GenOMICC was funded by Sepsis Research (the Fiona Elizabeth Agnew Trust), the Intensive Care Society, a Wellcome Trust Senior Research Fellowship (to J.K.B., 223164/Z/21/Z), the Department of Health and Social Care (DHSC), Illumina, LifeArc, the Medical Research Council, UKRI, a BBSRC Institute Program Support Grant to the Roslin Institute (BBS/E/D/20002172, BBS/E/D/10002070 and BBS/E/D/30002275) and UKRI grants MC_PC_20004, MC_PC_19025, MC_PC_1905 and MRNO2995X/1. A.D.B. acknowledges funding from the Wellcome PhD training fellowship for clinicians (204979/Z/16/Z), the Edinburgh Clinical Academic Track (ECAT) programme. This research is supported in part by the Data and Connectivity National Core Study, led by Health Data Research UK in partnership with the Office for National Statistics and funded by UK Research and Innovation (grant MC_PC_20029). Laboratory work was funded by a Wellcome Intermediate Clinical Fellowship to B.F. (201488/Z/16/Z). We acknowledge the staff at NHS Digital, Public Health England and the Intensive Care National Audit and Research Centre who provided clinical data on the participants; and the National Institute for Healthcare Research Clinical Research Network (NIHR CRN) and the Chief Scientist’s Office (Scotland), who facilitate recruitment into research studies in NHS hospitals, and to the global ISARIC and InFACT consortia. GenOMICC genotype controls were obtained using UK Biobank Resource under project 788 funded by Roslin Institute Strategic Programme Grants from the BBSRC (BBS/E/D/10002070 and BBS/E/D/30002275) and Health Data Research UK (HDR-9004 and HDR-9003). UK Biobank data were used in the GSMR analyses presented here under project 66982. The UK Biobank was established by the Wellcome Trust medical charity, Medical Research Council, Department of Health, Scottish Government and the Northwest Regional Development Agency. It has also had funding from the Welsh Assembly Government, British Heart Foundation and Diabetes UK. The work of L.K. was supported by an RCUK Innovation Fellowship from the National Productivity Investment Fund (MR/R026408/1). J.Y. is supported by the Westlake Education Foundation. SCOURGE is funded by the Instituto de Salud Carlos III (COV20_00622 to A.C., PI20/00876 to C.F.), European Union (ERDF) ‘A way of making Europe’, Fundación Amancio Ortega, Banco de Santander (to A.C.), Cabildo Insular de Tenerife (CGIEU0000219140 ‘Apuestas científicas del ITER para colaborar en la lucha contra la COVID-19’ to C.F.) and Fundación Canaria Instituto de Investigación Sanitaria de Canarias (PIFIISC20/57 to C.F.). We also acknowledge the contribution of the Centro National de Genotipado (CEGEN) and Centro de Supercomputación de Galicia (CESGA) for funding this project by providing supercomputing infrastructures. A.D.L. is a recipient of fellowships from the National Council for Scientific and Technological Development (CNPq)-Brazil (309173/2019-1 and 201527/2020-0)
A second update on mapping the human genetic architecture of COVID-19
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- Tucci A
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- Turebayeva G
- Turki S
- Turley C
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- Turnbull A
- Turner L
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- Turner V
- Turner-Bone I
- Turney S
- Turtle L
- Turvey SE
- Tusié-Luna T
- Tutt G
- Tutton R
- Twiss S
- Tyl D
- Tyler A
- Tzoulaki I
- Téllez L
- Uchimura Y
- Ueda S
- Ueda T
- Uellendahl-Werth F
- Uitterlinden AG
- Ullum H
- Umeda A
- Upadhyay KJ
- Upton J
- Urioste M
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- Uwamino Y
- Vadgama N
- Vadla MS
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- Valdés PA
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- Valenti L
- Valenzuela-Jorquera H
- Vallerga CL
- Valsecchi MG
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- Van Heel DA
- Van Heel DA
- Van Koutrick L
- Vandernoot I
- Varghese M
- Vasilevska-Ristovska J
- Vassell K
- Vedage D
- Veerapen K
- Vega J
- Vehreschild MJGT
- Velasco DG
- Velázquez-Cruz R
- Venkatesh H
- Verdugo RA
- Verdugo RA
- Vergasova E
- Verlander M
- Vertue M
- Verula J
- Vigueras-Hernández A
- Vigurs C
- Villa A
- Villalonga JM
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- Virgilio E
- Virginia M-RA
- Vitart V
- Vizcaychipi M
- Vlasschaert C
- Vochin A
- Volland S
- Von Hohenstaufen Puoti KA
- Voza A
- Vuylsteke A
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- Vázquez-Pérez JA
- Wacker EM
- Wackett T
- Wadams B
- Waddell G
- Waddington N
- Wagner R
- Wagstaff V
- Waite AAC
- Wakabayashi A
- Wakahara K
- Wakefield P
- Wakinshaw F
- Waldron J
- Walker C
- Walker D
- Walker L
- Walker R
- Walker S
- Walker S
- Wall A
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- Walter J
- Walters RK
- Walton O
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- Wang X
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- Whiteley S
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- Whitney J
- Whitton C
- Whyte C
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- Wiegrebe S
- Wienbrandt L
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- Wilding L
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- Wilfling S
- Wiliams A
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- Wilkinson B
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- Winkler TW
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- Wittig M
- Witzke O
- Wolf-Roberts R
- Wolford BN
- Wong I
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- Wong J
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- Woodward E
- Woodward J
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- Woolley AE
- Worner R
- Worsley L
- Wray G
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- Wrobel N
- Wu Y
- Wulandari R
- Wylie K
- Wyllie DH
- Wynter I
- Xavier K
- Xue X
- Yagi K
- Yamada M
- Yamada Y
- Yamagata K
- Yamasaki M
- Yang J
- Yaspan B
- Yassen AM
- Yasui Y
- Yates B
- Yatomi M
- Ye C
- Yermakovich D
- Yeung RSM
- Yi X
- Yonekawa A
- Yoo S
- Yoon K
- Yoshida K
- Yoshida S
- Yoshida S
- Yoshida T
- Yoshihara T
- Yoshiya K
- Yoshiyama T
- Young M
- Yue F
- Yun N
- Yáñez CE
- Yáñez Z
- Zainulabid UA
- Zainy T
- Zak A
- Zaki A
- Zamikula J
- Zamudio IPM
- Zanella A
- Zapata-Contreras D
- Zapatamartinez M
- Zarate R
- Zarei N
- Zavaleta DAF
- Zawadzki P
- Zawati MH
- Zborowski AC
- Zeberg H
- Zechner M
- Zhang Q
- Zhao X
- Zheng C
- Zheng T
- Zhlawi HJ
- Zhlawi MWJ
- Zholdybayeva E
- Zhou W
- Zhu W
- Zitter L
- Zoller H
- Zongo O
- Zorloni C
- Zuñiga-Pacheco P
- Zárate RN
- Zúñiga-Ramos J
- Álvarez BG
- Ávila-Arcos MA
- Ávila-Arcos MC
- Özer O
- Überla K
- Þorsteinsdóttir U
- Publication venue
- Nature Research
- Publication date
- 21/06/2023
- Field of study
Mapping the human genetic architecture of COVID-19
- Author
- Abdelrazik M
- Abdullah T
- Abe R
- Abe S
- Abecasis GR
- Abel L
- Abernathy C
- Abraheem A
- Abul-Husn NS
- Acosta-Herrera M
- Acquilini D
- Acquilini D
- Adachi T
- Adachi Y
- Adams C
- Adams K
- Adanini O
- Adeleye O
- Adeniji K
- Adra D
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agranoff D
- Agrawal S
- Aguirre LA
- Agwuh K
- Ahmad HF
- Ahmad N
- Ahmed A
- Ahmed C
- Ahmed KA
- Ai M
- Ail D
- Akeroyd L
- Akhtar MN
- Akhtar S
- Akinkugbe O
- Aksentijevich A
- Al Thani A
- Al-Muftah W
- Al-Sarraj Y
- Alarcon C
- Alarcon-Riquelme ME
- Alasdair F
- Alaverdian D
- Alavere H
- Albertos R
- Albillos A
- Albrecht W
- Albrich W
- Albrich WC
- Aldera EL
- Aldridge J
- Alegria A
- Alex B
- Alexander P
- Alfonso J
- Algera AG
- Ali A
- Ali IMA
- Ali S
- Aliberti S
- Allan A
- Allan E
- Allan J
- Alldis Z
- Allen L
- Allen S
- Allibone S
- Allison KS
- Allos R
- Ally SM
- Almaden-Boyle C
- Altabaibeh A
- Altmueller J
- Alvaro A
- Amar D
- Amin V
- Amitrano S
- Amiya S
- Ampuero J
- Anan R
- Anania S
- Anastasescu E
- Anderson F
- Anderson J
- Anderson M
- Anderson P
- Anderson S
- Anderson S
- Anderson T
- Ando A
- Andolfo I
- Andrade V
- Andretta F
- Andreucci E
- Andreucci E
- Andrew A
- Andrew B
- Andrew G
- Andrews E
- Andrews SJ
- Andrews SJ
- Andrews SJ
- Andrews SJ
- Andrikopoulos P
- Anedda F
- Aneli S
- Anemoli V
- Angelini C
- Angus B
- Annis A
- Antcliffe D
- Antinori A
- Antoni MD
- Anumakonda V
- Anwar M
- Anzai T
- Apetri E
- Arai D
- Arana E
- Arbane G
- Archer K
- Arciero E
- Arden T
- Arias SS
- Arif S
- Arimura K
- Armstrong J
- Armstrong JA
- Armstrong L
- Armstrong R
- Arning N
- Arnold S
- Arora J
- Artuso R
- Arumugam P
- Asakura T
- Asano K
- Aschard H
- Ascolillo S
- Ashish A
- Ashley E
- Ashraf S
- Ashraf S
- Ashton L
- Ashworth M
- Asiimwe IG
- Aslibekyan S
- Asselta R
- Atanasovska B
- Atkinson D
- Atkinson EG
- Attwood B
- Aucella F
- Augustin M
- Auld D
- Auld F
- Austin K
- Austin P
- Auton A
- Auton A
- Avendano-Ortiz J
- Awano N
- Ayers A
- Azarzar S
- Aziz F
- Azuma M
- Azuure C
- Azzolini E
- Baba R
- Baba T
- Bach B
- Bacher P
- Bachetti T
- Badalamenti S
- Badia JR
- Badji RM
- Bahmer T
- Baikady RR
- Baillie JK
- Baillie JK
- Baillie JK
- Baillie JK
- Baines B
- Baines D
- Baines K
- Baird T
- Baird Y
- Bakshi S
- Bakthavatsalam D
- Balaconis MK
- Baldassarri M
- Baldini M
- Ball CA
- Bals R
- Baltzell AH
- Bamford A
- Bamford P
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- Banagan J
- Banales JM
- Bancroft H
- Band G
- Bandera A
- Bandini M
- Bandla N
- Bano S
- Baptista D
- Barada O
- Baras A
- Baratti S
- Barber R
- Barbieri C
- Barbieri C
- Barbour A
- Barclay L
- Barclay WS
- Barda B
- Bargagli E
- Bari S
- Barker J
- Barlow G
- Barlow SL
- Barnass S
- Barnes KC
- Baroni S
- Baroni S
- Barreira A
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- Barrett KMS
- Barrett N
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- Barry P
- Bartels M
- Bartley S
- Baruah R
- Baselli G
- Bashyal A
- Basikolo C
- Bassetti M
- Bassford C
- Basso MEF
- Bastion V
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- Baya N
- Bayo L-A
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- Beadsworth M
- Beale R
- Bean S
- Beaumont K
- Beavis S
- Beck A
- Beckmann ND
- Beech E
- Beech V
- Beekes M
- Beesley K
- Begg C
- Beguin Y
- Behan T
- Beith CM
- Belagodu Z
- Belbin GM
- Belfield H
- Belhaj Y
- Beligni G
- Belisle A
- Bell D
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- Bellamy M
- Belli MA
- Bellinghausen C
- Bellini A
- Bellwood R
- Below JE
- Bemand T
- Benetti E
- Benham L
- Bennet D
- Bennett S
- Bentley M
- Benyon S
- Beppu S
- Beranova E
- Bercades G
- Bergan J
- Bergantini L
- Berger MM
- Bergomi M
- Bergomi P
- Berkowitz N
- Bernardo D
- Bernasconi A
- Bernatoniene J
- Berridge J
- Bertrand A
- Best N
- Bettini LR
- Beudel M
- Bevan E
- Bewley J
- Bhardwaj N
- Bhatia N
- Bhatterjee R
- Bhuie P
- Bi R
- Bianchi F
- Bianco C
- Bibert S
- Bibert S
- Bibi F
- Biddle J
- Biesecker L
- Biggs H
- Biondi A
- Birch J
- Birch J
- Birch S
- Birchall K
- Birchall K
- Bird S
- Birkinshaw I
- Birney E
- Birt M
- Biscarini F
- Black E
- Black K
- Blackledge B
- Blackledge B
- Blackman H
- Blakemore H
- Blanco-Grau A
- Blasi F
- Blay N
- Blay N
- Blow S
- Blunt M
- Boada M
- Board S
- Bocciardi R
- Bocciolone M
- Bochud M
- Bochud P-Y
- Bochud PY
- Bochud PY
- Bochud PY
- Bociek A
- Boer C
- Boezen M
- Bogaard HJ
- Bogaert D
- Boillat N
- Boillat-Blanco N
- Bokhari M
- Bolton M
- Bolton R
- Bolze A
- Bombace S
- Bomers M
- Bonfanti P
- Bonner S
- Bonta PI
- Booker L
- Booth L
- Booth S
- Borislavova B
- Borra C
- Bos L
- Bosari S
- Bosio G
- Bosse Y
- Botello A
- Bothma P
- Botta G
- Botta M
- Boua PR
- Bouab M
- Bough L
- Boughton AP
- Boujemla B
- Bouras K
- Boutros P
- Bouysran Y
- Bowes A
- Bowles R
- Boyle P
- Boyle R
- Boz C
- Bradford Y
- Bradley C
- Bradley P
- Bradley-Potts J
- Bradshaw Z
- Brady A
- Brady M
- Brady R
- Brahier T
- Brandwood C
- Branney D
- Brantwood C
- Brassard N
- Braun A
- Braun N
- Brayne A
- Brealey D
- Brealey D
- Breen G
- Bremmer P
- Brennan B
- Brenner B
- Brenner T
- Bretherick AD
- Brett M
- Brett S
- Brickell K
- Bridgett V
- Brimfield L
- Brinkworth E
- Briton K
- Brittain-Long R
- Britvan B
- Bromley M
- Brooke H
- Brooks S
- Brouwer MC
- Brown A
- Brown A
- Brown A
- Brown CW
- Brown E
- Brown J
- Bruce M
- Brunak S
- Bruno R
- Brunton M
- Brusco A
- Bruttini M
- Bryant J
- Bryant S
- Bryant S
- Buckley C
- Buckley S
- Bugiani M
- Bujanda L
- Bulik CM
- Bulle E
- Bullock K
- Bulteel N
- Bunni L
- Burda D
- Burden T
- Burn I
- Burnett C
- Burns K
- Burt K
- Burtenshaw A
- Burtenshaw A
- Burton M
- Busani S
- Busson A
- Bussotti M
- Bustamante C
- Butcher D
- Buti M
- Butler A
- Butler S
- Butler-Laporte G
- Butler-Laporte G
- Butler-Laporte G
- Butler-Laporte G
- Butte MJ
- Butterworth AS
- Butterworth-Cowin N
- Button H
- Buxbaum JD
- Buxbaum JD
- Buxbaum JD
- Byun J
- Caba Llero-Garralda A
- Cabrelli L
- Caceres M
- Cadilla CL
- Cagova L
- Caldarelli GP
- Calderon EJ
- Callaghan M
- Callier S
- Camby S
- Cameli P
- Campbell A
- Campbell H
- Campbell R
- Campbell R
- Campos S
- Camsooksai J
- Canaccini A
- Canakoglu A
- Cantarini L
- Cantor MN
- Capasso M
- Capitani K
- Cappadona C
- Cappelli S
- Capps N
- Carbral-Ortega L
- Cardamone G
- Carella M
- Carey DJ
- Carli D
- Carlucci N
- Carmody M
- Carmody S
- Carnahan M
- Carnero-Montoro E
- Carrabba M
- Carracedo AD
- Carreras Nolla A
- Carreras A
- Carriero ML
- Carson G
- Carter A
- Carter E
- Carter J
- Carter S
- Carungcong J
- Caruth V
- Casey M
- Cass E
- Castano-Vinyals G
- Castelli F
- Castle K
- Castoldi M
- Castori M
- Castro P
- Caswell M
- Catena E
- Caterson J
- Cathcart S
- Catlow L
- Catterall BWA
- Caulfield MJ
- Caulfield MJ
- Cavazza A
- Cawley K
- Cawthron K
- Cazzaniga M
- Cea C
- Cecconi M
- Ceri S
- Ceri S
- Ceriotti F
- Cerny A
- Cerrato L
- Chablani M
- Chadbourn I
- Chadwick D
- Chadwick D
- Chambler D
- Chan G
- Chan R
- Chand M
- Chandler B
- Chang D
- Chang TS
- Chang X
- Chang Y
- Chapman S
- Charles B
- Charlesworth R
- Charney AW
- Charnock R
- Chasse M
- Chassot J
- Chaudhary K
- Chavan S
- Chechi K
- Chee N
- Cheema Y
- Chen H-H
- Cheng N
- Cherian S
- Chernitsov A
- Cherubini A
- Chetam L
- Cheyne C
- Chiba S
- Chihara Y
- Child J
- Childs D
- Chittoor G
- Chiu A
- Cho JH
- Cho K
- Choe K-W
- Choi S
- Chouchane O
- Choudhury Y
- Chowdhury M
- Christle J
- Chubachi S
- Chueca N
- Chukkambotla S
- Chukkambotla S
- Chung R
- Chung W
- Churchhouse C
- Chwialkowska K
- Chwialkowska K
- Ciccarelli M
- Ciesek S
- Cirulli ET
- Claassen S
- Claire W
- Clamp S
- Clapham M
- Claringbould A
- Clarinval M
- Clark A
- Clark JJ
- Clark M
- Clark M
- Clark R
- Clark R
- Clark S
- Clark T
- Clark V
- Clarke D
- Clarke EA
- Clarke N
- Clarkson M
- Clayton S
- Clement I
- Clements S
- Clerc O
- Cloherty A
- Clohisey S
- Clohisey S
- Clohisey S
- Clohisey S
- Coates C
- Cockrell M
- Coetzee S
- Coghlan P
- Coignet M
- Coiro G
- Coker D
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- Cole J
- Cole S
- Cole S
- Cole S
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- Coles H
- Colley J
- Collier D
- Collier D
- Colligan G
- Collignon A
- Collignon A
- Collini P
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- Collins BL
- Collins C
- Collins E
- Collins E
- Collins K
- Collis M
- Colombo F
- Colombo R
- Combes E
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- Connor M
- Conticini E
- Convery K
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- Cooke GS
- Cooper J
- Cooper L
- Cooper L
- Corcoran E
- Cordero AIH
- Cordioli M
- Cordioli M
- Cordioli M
- Cordioli M
- Cordioli M
- Cordioli M
- Cordioli M
- Cornberg M
- Cornell S
- Cornely OA
- Corral MA
- Correia GDS
- Corridi M
- Cortes B
- Cortes B
- Cosgrove C
- Cosgrove D
- Cosier T
- Cossarizza A
- Costantino G
- Cother N
- Coton Z
- Coulding M
- Coutts A
- Coventry T
- Coviello DA
- Cowley A
- Cowley A
- Cowley N
- Cowton A
- Cox A
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- Cox NJ
- Coyle J
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- Crew A
- Crickmore V
- CRiPSI
- Crisp N
- Criste K
- Cristiano D
- Croci L
- Croci S
- Croft M
- Crook DW
- Crooks K
- Crotti L
- Crowe R
- Crowley M
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- Cunningham M
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- Cupitt J
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- Curtis CJ
- Cusack R
- Cusick C
- Cutino-Moguel M-T
- Cutler S
- D'Acremont V
- D'Alessandro M
- D'Amato M
- D'Angio M
- D'Sylva S
- Da Gloria EF
- Dabe S
- Daga S
- Daglish J
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- Dalton K
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- Daly MJ
- Daly Z
- Dalziel J
- Damas JK
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- Danesh J
- Daniel A
- Daniel P
- Daniels A
- Darcis G
- Dark P
- Dark P
- Darlington K
- Darwish D
- Dasgin J
- Daubney E
- Davey M
- Davey M
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- David C
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- Davies G
- Davies K
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- Davies M
- Davies M
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- Davis LK
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- Day N
- Daya M
- de Brabander J
- de Bree G
- de Bruin S
- de Cid R
- de Cid R
- de Geus EJC
- de Gordoa LO-R
- de Gordoa LO-R
- De Grandi A
- de Jong H
- de Jong MD
- De la Horra C
- De Neef M
- de Pablo R
- de Rojas I
- de Salazar A
- de Silva T
- De Vivo O
- De Vivo O
- de Vries H
- Deacon B
- Deacon B
- Dearden J
- Death Y
- Deboever C
- Debreceni G
- Deelen P
- Deelen P
- Deery J
- Degenhardt F
- Dei S
- Dela Rosa A
- Delaneau O
- Delgado CC
- Delgado J
- Della Monica M
- Dellot P
- Deloukas P
- Demetriou C
- Denmade C
- Dennis C
- Dent K
- Dent M
- Depante M
- Dervisevic S
- Desanctis E
- Desgranges F
- deSouza F
- Di Angelantonio E
- di Bartolomeo C
- Di Biagio A
- Di Domenico P
- Di Pietro M
- Di Sarno L
- Di Valentin E
- Digby B
- Digby S
- Dincarslan O
- Ding L
- Ding Y
- Djeugam B
- Do R
- Dobano C
- Dobson E
- Docherty AB
- Doddato G
- Dodds S
- Domingues F
- Donaldson A
- Donaldson D
- Donati A
- Dongelmans D
- Donlon S
- Donnachie J
- Donne B
- Donnelly K
- Donnelly L
- Donner K
- Donnison P
- Donnison P
- Donohue C
- Dooks E
- Doonan R
- Dopazo X
- Dore R
- Dormand N
- Douglas K
- Douthwaite S
- Downes C
- Drake TM
- Dreher M
- Drummond A
- Drummond A
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- Dudman S
- Dueker N
- Duffield J
- Duffin D
- Duffy K
- Duffy S
- Duga S
- Duga S
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- Dumas M-E
- Duncan E
- Duncan T
- Dunham I
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- Valente S
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- Valentine J
- Valentino F
- Valino K
- Vallerga C
- Vallotton N
- Valsecchi MG
- van Agtmael M
- van Baarle F
- van Blokland I
- van de Beek D
- van den Berge M
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- van der Valk M
- van Heel D
- van Heel DA
- van Heel DA
- van Koutrik L
- van Mourik N
- Van Singer M
- van Tonder L
- van Uffelen KWJ
- van Vugt M
- Vandernoot I
- Varghese M
- Vari MS
- Varnai R
- Vecchia M
- Vedage D
- Veelo D
- Veerapen K
- Veerapen K
- Veerapen K
- Vehreschild MJGT
- Velho M
- Venkatesh H
- Venturelli S
- Verdugo RA
- Vergori A
- Verlander M
- Verma A
- Verma SS
- Vertue M
- Vertue M
- Verula J
- Verzuri A
- Viala B
- Vigurs C
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- Vincent-Smith L
- Vincenti A
- Viollet RM
- Visuvanathan S
- Vitart V
- Vizcaychipi MP
- Vlaar APJ
- Vochin A
- Voide C
- Voide C
- Volland S
- Vollenweider P
- Vollenweider P
- Von Frenckell C
- von Hohenstaufen K
- von Mering C
- Vonk JM
- Voza A
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- Vuylsteke A
- Vuylsteke A
- Wacker EM
- Wackett T
- Wadams B
- Waddington N
- Waddy S
- Wagstaff V
- Waite AAC
- Wakabayashi A
- Wakahara K
- Wake R
- Wakefield P
- Wakinshaw F
- Walden A
- Waldron J
- Walker D
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- Walters RK
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- Wang B
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- Wang J
- Wang Q
- Wang X
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- Ward G
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- Washington NL
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- Watanabe K
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- Watson N
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- Waugh V
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- Welters ID
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- Wery M
- Wesse T
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- Whiteley S
- Whiteside J
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- Wiersinga WJ
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- Wiselka M
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- Woodyatt W
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- Wooton DG
- Working UCLAHATLASDM
- Workman A
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- Worsley L
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- Wu Y
- Wulandari R
- Wyllie DH
- Wynter I
- Xavier K
- Xue X
- Yadav A
- Yagi K
- Yamada M
- Yamada Y
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- Yang Z
- Yaspan B
- Yasui Y
- Yates B
- Yates B
- Yatomi M
- Ye C
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- Yermakovich D
- Yi X
- Yonekawa A
- Yoon H
- Yoon KJ
- Yoshida K
- Yoshida S
- Yoshida S
- Yoshida T
- Yoshihara T
- Yoshiya K
- Yoshiyama T
- Youlton N
- Younes SE
- Young P
- Yun N
- Zak A
- Zaki A
- Zambon M
- Zamikula J
- Zanella A
- Zanella I
- Zanelli G
- Zara F
- Zara F
- Zarate R
- Zarate R
- Zborowski AC
- Zeberg H
- Zechner M
- Zechner M
- Zguro K
- Zhai R
- Zhang JE
- Zhang M
- Zhao JH
- Zhen J
- Zheng C
- Zheng T
- Zhou W
- Zhou W
- Zhu W
- Zitter L
- Zlatopolsky M
- Zoller H
- Zollner S
- Zongo O
- zu Bentrup FM
- Zucchi P
- Zwinderman AHK
- Zyndorf M
- Publication venue
- Publication date
- 01/01/2021
- Field of study
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3,4,5,6,7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease