Simulation of diffractive and non-diffractive processes at the LHC energy with the PYTHIA and PHOJET MC event generators

The predictions of the PYTHIA6.205 and PHOJET1.12 MC event generators for diffractive processes and minimum bias events are presented for the LHC energy. The comparison with the experimental data from the ISR, the SPS and the Tevatron is made

Prévalence en anticorps contre le virus de la fièvre de la vallée du Rift chez les petits ruminants du Sénégal

Une enquête de prévalence en anticorps contre le virus de la fièvre de la Vallée du Rift a été réalisée sur un échantillon représentatif du cheptel ovin et caprin du Sénégal. La répartition des anticorps montre l'état enzootique de la fièvre de la vallée du Rift dans ce cheptel. Les prévalences en anticorps chez les ovins et caprins sont comparables mais réparties de façon très hétérogène selon les zones étudiées (Résumé d'auteur

Centrality dependence of K+ produced in Pb+Pb collisions at 158 GeV per nucleon

The NA52 collaboration searches for a discontinuous behaviour of charged kaons produced in Pb+Pb collisions at 158 A GeV as a function of the impact parameter, which could reveal a hadron to quark-gluon plasma (QGP) phase transition. The K+ yield is found to grow proportional to the number of participating ('wounded') nucleons N, above N=100. Previous NA52 data agree with the above finding and show a discontinuous behaviour in the kaon centrality dependence near N=100, marking the onset of strangeness enhancement -over e.g. p+A data at the same \sqrt{s}- in a chemically equilibrated phase.Comment: 2 pages, 2 figures, submitted to the XXXth International Conference on High Energy Physics, 27 July - 2 August, 2000, Osaka, Japa

Intercalibration of the barrel electromagnetic calorimeter of the CMS experiment at start-up

Calibration of the relative response of the individual channels of the barrel electromagnetic calorimeter of the CMS detector was accomplished, before installation, with cosmic ray muons and test beams. One fourth of the calorimeter was exposed to a beam of high energy electrons and the relative calibration of the channels, the intercalibration, was found to be reproducible to a precision of about 0.3%. Additionally, data were collected with cosmic rays for the entire ECAL barrel during the commissioning phase. By comparing the intercalibration constants obtained with the electron beam data with those from the cosmic ray data, it is demonstrated that the latter provide an intercalibration precision of 1.5% over most of the barrel ECAL. The best intercalibration precision is expected to come from the analysis of events collected in situ during the LHC operation. Using data collected with both electrons and pion beams, several aspects of the intercalibration procedures based on electrons or neutral pions were investigated

Low mass dimuon production in proton and ion induced interactions at SPS

The low mass dimuon spectra collected in p-U collisions by the NA38 experiment significantly exceeds the total cross section expected from previous analysis, done by other experiments. The `excess' events have a harder \pt\ distribution than the muon pairs from $\eta$ and $\omega$ Dalitz decays, expected to dominate the mass window 0.4--0.65~GeV/$c^2$. We conjecture that the excess events might be due to \qqbar\ annihilations, negligible at low \pt\ but made visible by the \mt\ cut applied in the NA38 data. Taking this assumption to parametrise the p-U spectra, we proceed with the analysis of the S-Cu, S-U and Pb-Pb data, collected by the NA38 and NA50 experiments, where we find that the measured mass spectra does not seem to exceed the expected low mass `cocktail' by more than 20\,\%

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

A locus at 19p13 is associated with breast cancer (BC) and ovarian cancer (OC) risk. Here we analyse 438 SNPs in this region in 46,451 BC and 15,438 OC cases, 15,252 BRCA1 mutation carriers and 73,444 controls and identify 13 candidate causal SNPs associated with serous OC (P=9.2 × 10-20), ER-negative BC (P=1.1 × 10-13), BRCA1-associated BC (P=7.7 × 10-16) and triple negative BC (P-diff=2 × 10-5). Genotype-gene expression associations are identified for candidate target genes ANKLE1 (P=2 × 10-3) and ABHD8 (P<2 × 10-3). Chromosome conformation capture identifies interactions between four candidate SNPs and ABHD8, and luciferase assays indicate six risk alleles increased transactivation of the ADHD8 promoter. Targeted deletion of a region containing risk SNP rs56069439 in a putative enhancer induces ANKLE1 downregulation; and mRNA stability assays indicate functional effects for an ANKLE1 3′-UTR SNP. Altogether, these data suggest that multiple SNPs at 19p13 regulate ABHD8 and perhaps ANKLE1 expression, and indicate common mechanisms underlying breast and ovarian cancer risk