Bases biologiques de l'association chimio-radiotherapie. Applications aux cancers du poumon

Radiation therapy has been for years the treatment of choice of locally advanced non small cell lung cancer. Improvement due to the combination of radiation and chemotherapy has been shown recently through several randomized trials and a recent meta-analysis. These results may be explained by biological mechanisms, yet uncompletely explored, which are detailed in this review and applied to lung cancer. The optimal combination scheme is not yet defined, even though the concurrent approach is promising, at the expense of an increased toxicity which is the limiting factor of treatment escalation doses. Biological findings and future results of randomized trials will hopefully open new avenues in the therapeutic strategy of this poor prognosis disease.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Modification in the binding domain of ENV genes to redirect ALV host-ranges

International audienc

EP-1581: Salvage brachytherapy and a rectal spacer in locally recurrent prostate cancer after radiotherapy

International audienc

Persistent improved results after adding vincristine and bleomycin to a cyclophosphamide/hydroxorubicin/Vm-26/prednisone combination (CHVmP) in stage III-IV intermediate- and high-grade non-Hodgkin's lymphoma

SCOPUS: cp.jinfo:eu-repo/semantics/publishe