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Quarterly review of 241-SY-101 mixer pump data: October - December, 1998
This report presents data obtained on 241-SY-101 pump performance. The period covered is October 1 through December 31, 1998. During the quarter: (1) There was an indication of a 7.0-inch increase in the waste level at riser lA, and an average growth rate of 0.076 inches per day. (2) There was an indication of a 2.3-inch increase in the waste level at riser 1C. This riser was flushed with water several times, which would lower the level of the crust at this location. (3) Gases continued to be released at less than the pre-pump installation baseline rate, indicating a decrease in the gas generation rate, or an increase in gas retention, or both. The release rate was about 60 percent of the rate in the previous few quarters, and only 44 percent of the pre-pump release rate. (4) There was no change in the parameters that monitor pump performance. Key controls exist for waste temperature, gas concentration, pump parameters, and long-term waste behavior associated with the safe operation of the mixer pump that mitigates the buoyant displacement gas release event behavior of 241-SY-101. Table 1-1 compares the key controls and the current state of the waste as of December 31, 1998
Geometric K-Homology of Flat D-Branes
We use the Baum-Douglas construction of K-homology to explicitly describe
various aspects of D-branes in Type II superstring theory in the absence of
background supergravity form fields. We rigorously derive various stability
criteria for states of D-branes and show how standard bound state constructions
are naturally realized directly in terms of topological K-cycles. We formulate
the mechanism of flux stabilization in terms of the K-homology of non-trivial
fibre bundles. Along the way we derive a number of new mathematical results in
topological K-homology of independent interest.Comment: 45 pages; v2: References added; v3: Some substantial revision and
corrections, main results unchanged but presentation improved, references
added; to be published in Communications in Mathematical Physic
Replication is more than hitting the lottery twice
The main goal of our target article was to provide concrete recommendations for improving the replicability of research findings. Most of the comments focus on this point. In addition, a few comments were concerned with the distinction between replicability and generalizability and the role of theory in replication. We address all comments within the conceptual structure of the target article, and hope to convince readers that replication in psychological science amounts to much more than hitting the lottery twice
Botulism: a laboratory investigation on biological and food samples from cases and outbreaks in Brazil (1982-2001)
Adenosine A2A receptors modulate BDNF both in normal conditions and in experimental models of Huntington’s disease
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, enhances synaptic transmission and regulates neuronal proliferation and survival. Functional interactions between adenosine A2A receptors (A2ARs) and BDNF have been recently reported. In this article, we report some recent findings from our group showing that A2ARs regulate both BDNF functions and levels in the brain. Whereas BDNF (10 ng/ml) increased the slope of excitatory postsynaptic field potentials (fEPSPs) in hippocampal slices from wild-type (WT) mice, it was completely ineffective in slices taken from A2AR knock-out (KO) mice. Furthermore, enzyme immunoassay studies showed a significant reduction in hippocampal BDNF levels in A2AR KO vs. WT mice. Having found an even marked reduction in the striatum of A2AR KO mice, and as both BDNF and A2ARs have been implicated in the pathogenesis of Huntington’s disease (HD), an inherited striatal neurodegenerative disease, we then evaluated whether the pharmacological blockade of A2ARs could influence striatal levels of BDNF in an experimental model of HD-like striatal degeneration (quinolinic acid-lesioned rats) and in a transgenic mice model of HD (R6/2 mice). In both QA-lesioned rats and early symptomatic R6/2 mice (8 weeks), the systemic administration of the A2AR antagonist SCH58261 significantly reduced striatal BDNF levels. These results indicate that the presence and the tonic activation of A2ARs are necessary to allow BDNF-induced potentiation of synaptic transmission and to sustain a normal BDNF tone. The possible functional consequences of reducing striatal BDNF levels in HD models need further investigation
Atenção humanizada ao recém-nascido de baixo-peso. Método Canguru e cuidado centrado na família: correspondências e especificidades
Primordial Nucleosynthesis for the New Cosmology: Determining Uncertainties and Examining Concordance
Big bang nucleosynthesis (BBN) and the cosmic microwave background (CMB) have
a long history together in the standard cosmology. The general concordance
between the predicted and observed light element abundances provides a direct
probe of the universal baryon density. Recent CMB anisotropy measurements,
particularly the observations performed by the WMAP satellite, examine this
concordance by independently measuring the cosmic baryon density. Key to this
test of concordance is a quantitative understanding of the uncertainties in the
BBN light element abundance predictions. These uncertainties are dominated by
systematic errors in nuclear cross sections. We critically analyze the cross
section data, producing representations that describe this data and its
uncertainties, taking into account the correlations among data, and explicitly
treating the systematic errors between data sets. Using these updated nuclear
inputs, we compute the new BBN abundance predictions, and quantitatively
examine their concordance with observations. Depending on what deuterium
observations are adopted, one gets the following constraints on the baryon
density: OmegaBh^2=0.0229\pm0.0013 or OmegaBh^2 = 0.0216^{+0.0020}_{-0.0021} at
68% confidence, fixing N_{\nu,eff}=3.0. Concerns over systematics in helium and
lithium observations limit the confidence constraints based on this data
provide. With new nuclear cross section data, light element abundance
observations and the ever increasing resolution of the CMB anisotropy, tighter
constraints can be placed on nuclear and particle astrophysics. ABRIDGEDComment: 54 pages, 20 figures, 5 tables v2: reflects PRD version minor changes
to text and reference
Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study
A41 Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study
In: Addiction Science & Clinical Practice 2017, 12(Suppl 1): A4
Characteristics of stress relaxation kinetics of La 60 Ni 15 Al 25 bulk metallic glass
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