Nuevos datos magnetoestratigráficos del tránsito Oligoceno-Mioceno en el sector SE de la Cuenca del Ebro (provincia de Lleida, Zaragoza y Huesca, NE de España)

The study of two late Oligocene-early Miocene stratigraphic sections of alluvial and shallow lacustrine facies in the SE Ebro Basin has enabled the establishment of a high-resolution magnetostratigraphy for the Oligocene-Miocene boundary. The studied samples include alluvial sandstones and mudstones as well as shallow lacustrine limestones. A total of 121 stratigraphic levels, with an average sample spacing of -2.5 m, were sampled in two sections, using a portable gasoline powered dril1 machine. Core samples were cut in the laboratory into two or three standard specimens of 2.54 cm diameter X 2.1 cm in length. A minimum of two specimens per site were thermally or AF demagnetized in 8-9 steps at intervals of 50°C or 30°C, and intervals of 2.5 mT and 5 mT, respectively. The magnetic polarity zonation of the sections have been correlated to the Geomagnetic Polarity Time Scale (GPTS) allowing the recognition of Chrons 9r, 9n, 8r and 8n in the Mina Pilar section, and Chrons 6Cr, 6Cn, 6Br, 6Bn and 6AAr in the Valcuerna section. On the basis of magnetostratigraphic correlation it is deduced an interval of sedimentation time of -1.6 Ma for the Mina Pilar section, and 1.7-1.9 Ma for the Valcuerna section

Condroblastoma de astrágalo: localización inusual

Se expone 1 caso de un condroblastoma de astrágalo en 1 paciente de 17 años. Esta tumoración, definida como tal en 1942 por Jaffe y Lichtenstein, presenta un comportamiento benigno que responde al tratamiento mediante curetaje e injerto óseo de la cavidad. A pesar de este comportamiento benigno se hace mención a la posibilidad de metástasis pulmonares y a la agresividad local en algunos casos.A 17-year-old man with chondroblastoma of the talus is reported. This tumor described in 1942 by Jaffe and Lichtenstein has a benign behavior and a good response to surgical treatment by curetage of the cavity and bone graft. In certain cases local aggresivity and lung metastasis has been described

Expression and antiviral activity of a β-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences

The in silico identification of a β-defensin-like peptide sequence (omBD-1) in the rainbow trout (Oncorhynchuss mykiss) database of salmonid EST is reported here. We have studied the transcript expression of this β-defensin-like sequence in different organs and expressed the recombinant peptide in a fish cell line. Finally, we have demonstrated the in vitro antiviral activity of the recombinant trout β-defensin-like peptide against viral haemorrhagic septicaemia rhabdovirus (VHSV), one of the most devastating viruses for worldwide aquaculture. Thus, the resistance to VHSV infection of EPC cells transfected with pMCV 1.4-omBD-1 has been shown. Since EPC cells transfected with omBD-1 produced acid and heat stable antiviral activity and up regulation of Mx, a type I IFN-mediated mechanism of antiviral action is suggested. To our knowledge, this is the first report showing biological activity of a β-defensin-like peptide from any fish

Effect of high pressure processing temperature on dry-cured hams with different textural characteristics

High pressure processing is mainly used to eliminate pathogenic microorganisms and extend the shelf-life of dry-cured hams, but it also modifies its texture. These changes might be different depending on the initial textural characteristics. In this study, texture, colour and colour stability were evaluated after pressurization at 600 MPa during 6 min at 7 ºC, 20 ºC and 35 ºC in samples with different textural characteristics (no pastiness, medium and high pastiness groups). HP treatments produced an increase of hardness (F0) and lightness (L*) values and a decrease of softness/pastiness (Y2 and Y90) and redness (a*) values at any processing temperatures. However, the increase of F0 and L* values was more pronounced in non–pasty samples. In samples with high pastiness and softness, HP processing at high temperature (35ºC) reduced the intensity of pastiness. However, texture of hams with non-pasty texture might be negatively affected. Therefore, the optimal temperature of HP processing depends on the textural characteristics of dry-cured hams.info:eu-repo/semantics/acceptedVersio

Evolución de la Biomecánica Deportiva a partir de las tesis doctorales realizadas en España entre los años 1980 y 2019

El objeto de este estudio es realizar una revisión de las tesis doctorales que se han leído en España en el campo de la Biomecánica Deportiva durante el periodo comprendido entre 1980 y 2019 para conocer la producción científica, los datos de autoría y dirección, y los referentes institucionales que les han dado cobertura académica. La muestra ha quedado compuesta de 233 tesis después de un proceso de selección con el uso de criterios de inclusión/exclusión y términos de búsqueda específicos. Los resultados ponen de manifiesto que la producción de tesis en Biomecánica deportiva ha sido exponencial a lo largo de los periodos analizados. El 90,6% de las tesis se han leído en universidades públicas y el 9,4% en privadas. Tanto en la autoría, como en la dirección de las tesis, existe una presencia mayoritaria de hombres. A pesar de la progresiva y creciente presencia de la mujer como autoras de las tesis, el 69,5% están realizadas por hombres y en el caso de la dirección de las tesis, la presencia de la mujer es incluso, más reducida, con un 81,5% de las tesis dirigidas solo por hombresPeer Reviewe

The immunogenicity of viral haemorragic septicaemia rhabdovirus (VHSV) DNA vaccines can depend on plasmid regulatory sequences

A plasmid DNA encoding the viral hemorrhagic septicaemia virus (VHSV)-G glycoprotein under the control of 5′ upstream sequences (enhancer/promoter sequence plus both non-coding 1st exon and 1st intron sequences) from carp β-actin gene (pAE6-GVHSV) was compared to the vaccine plasmid usually described the gene expression is regulated by the human cytomegalovirus (CMV) immediate-early promoter (pMCV1.4-GVHSV). We observed that these two plasmids produced a markedly different profile in the level and time of expression of the encoded-antigen, and this may have a direct effect upon the intensity and suitability of the in vivo immune response. Thus, fish genetic immunisation assays were carried out to study the immune response of both plasmids. A significantly enhanced specific-antibody response against the viral glycoprotein was found in the fish immunised with pAE6-GVHSV. However, the protective efficacy against VHSV challenge conferred by both plasmids was similar. Later analysis of the transcription profile of a set of representative immune-related genes in the DNA immunized fish suggested that depending on the plasmid-related regulatory sequences controlling its expression, the plasmid might activate distinct patterns of the immune system. All together, the results from this study mainly point out that the selection of a determinate encoded-antigen/vector combination for genetic immunisation is of extraordinary importance in designing optimised DNA vaccines that, when required for inducing protective immune response, could elicit responses biased to antigen-specific antibodies or cytotoxic T cells generation

A High Luminosity e+e- Collider to study the Higgs Boson

A strong candidate for the Standard Model Scalar boson, H(126), has been discovered by the Large Hadron Collider (LHC) experiments. In order to study this fundamental particle with unprecedented precision, and to perform precision tests of the closure of the Standard Model, we investigate the possibilities offered by An e+e- storage ring collider. We use a design inspired by the B-factories, taking into account the performance achieved at LEP2, and imposing a synchrotron radiation power limit of 100 MW. At the most relevant centre-of-mass energy of 240 GeV, near-constant luminosities of 10^34 cm^{-2}s^{-1} are possible in up to four collision points for a ring of 27km circumference. The achievable luminosity increases with the bending radius, and for 80km circumference, a luminosity of 5 10^34 cm^{-2}s^{-1} in four collision points appears feasible. Beamstrahlung becomes relevant at these high luminosities, leading to a design requirement of large momentum acceptance both in the accelerating system and in the optics. The larger machine could reach the top quark threshold, would yield luminosities per interaction point of 10^36 cm^{-2}s^{-1} at the Z pole (91 GeV) and 2 10^35 cm^{-2}s^{-1} at the W pair production threshold (80 GeV per beam). The energy spread is reduced in the larger ring with respect to what is was at LEP, giving confidence that beam polarization for energy calibration purposes should be available up to the W pair threshold. The capabilities in term of physics performance are outlined.Comment: Submitted to the European Strategy Preparatory Group 01-04-2013 new version as re-submitted to PRSTA

Ladder approximation to spin velocities in quantum wires

The spin sector of charge-spin separated single mode quantum wires is studied, accounting for realistic microscopic electron-electron interactions. We utilize the ladder approximation (LA) to the interaction vertex and exploit thermodynamic relations to obtain spin velocities. Down to not too small carrier densities our results compare well with existing quantum Monte-Carlo (QMC) data. Analyzing second order diagrams we identify logarithmically divergent contributions as crucial which the LA includes but which are missed, for example, by the self-consistent Hartree-Fock approximation. Contrary to other approximations the LA yields a non-trivial spin conductance. Its considerably smaller computational effort compared to numerically exact methods, such as the QMC method, enables us to study overall dependences on interaction parameters. We identify the short distance part of the interaction to govern spin sector properties.Comment: 6 pages, 6 figures, to appear in Physical Review