128 research outputs found
Gravitational Collapse: Expanding and Collapsing Regions
We investigate the expanding and collapsing regions by taking two well-known
spherically symmetric spacetimes. For this purpose, the general formalism is
developed by using Israel junction conditions for arbitrary spacetimes. This
has been used to obtain the surface energy density and the tangential pressure.
The minimal pressure provides the gateway to explore the expanding and
collapsing regions. We take Minkowski and Kantowski-Sachs spacetimes and use
the general formulation to investigate the expanding and collapsing regions of
the shell.Comment: 12 pages, 4 figures, accepted for publication in Gen. Relativ. Gra
Phase Separation of Rigid-Rod Suspensions in Shear Flow
We analyze the behavior of a suspension of rigid rod-like particles in shear
flow using a modified version of the Doi model, and construct diagrams for
phase coexistence under conditions of constant imposed stress and constant
imposed strain rate, among paranematic, flow-aligning nematic, and log-rolling
nematic states. We calculate the effective constitutive relations that would be
measured through the regime of phase separation into shear bands. We calculate
phase coexistence by examining the stability of interfacial steady states and
find a wide range of possible ``phase'' behaviors.Comment: 23 pages 19 figures, revised version to be published in Physical
Review
Cosmological Black Holes on Branes
We examined analytically a cosmological black hole domain wall system. Using
the C-metric construction we derived the metric for the spacetime describing an
infinitely thin domain wall intersecting a cosmological black hole. We studied
the behaviour of the scalar field describing a self-interacting cosmological
domain wall and find the approximated solution valid for large distances. The
thin wall approximation and the back raection problem were elaborated finding
that the topological kink solution smoothed out singular behaviour of the zero
thickness wall using a core topological and hence thick domain wall. We also
analyze the nucleation of cosmological black holes on and in the presence of a
domain walls and conclude that the domain wall will nucleate small black holes
on it rather than large ones inside.Comment: 13 pages, Revtex, to be published in Phys.Rev. D1
Astrochemistry - Complex organic matter in Titan's aerosols? Reply
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62938/1/nature05418.pd
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A mixed-methods feasibility study of a novel AI-enabled, web-based, clinical decision support system for the treatment of major depression in adults
Background:-
The objective of this paper is to discuss perceived clinical utility and impact on physician-patient relationship of a novel, artificial-intelligence (AI) enabled clinical decision support system (CDSS) for use in treating adults with major depression.
Methods:-
A single arm, naturalistic follow-up study aimed at assessing the acceptability and useability of the software. Patients had a baseline appointment, followed by a minimum of two appointments with the CDSS. Study exit questionnaires and interviews were conducted to assess perceived clinical utility, impact on patient-physician relationship, and understanding and trust. 7 physicians and 17 patients, of which 14 completed, consented to participate.
Results:-
86 % of physicians (6/7) felt the information provided by the CDSS provided more comprehensive understanding of patient situations. 71 % (5/7) felt the information was helpful. 86 % of physicians (6/7) reported the AI/predictive model was useful when deciding treatment. 62 % of patients (8/13) reported improved care due to the tool, and 46 %(6/13) reported a significantly or somewhat improved physician-patient relationship 54 % reported no change. 71 % of physicians (5/7) and 62 % of patients (8/13) rated trusting the tool.
Limitations:-
Small sample size and treatment changes prior to CDSS introduction limits ability to verify impact on outcomes.
Conclusions:-
Qualitative results from 12 patient exit interviews are analyzed and presented. Findings suggest physicians perceived the tool as useful in conducting appointments and used it while deciding treatment. Physicians and patients generally found the tool trustworthy, and it may have positive effects on physician-patient relationships. (Study identifier: NCT04061642)
“Help! I Need Somebody”: Music as a global resource for obtaining wellbeing goals in times of crisis
Health and self-regulatio
Evaluating the clinical feasibility of an artificial intelligence–powered, web-based clinical decision support system for the treatment of depression in adults: longitudinal feasibility study
Background:- Approximately two-thirds of patients with major depressive disorder do not achieve remission during their first treatment. There has been increasing interest in the use of digital, artificial intelligence–powered clinical decision support systems (CDSSs) to assist physicians in their treatment selection and management, improving the personalization and use of best practices such as measurement-based care. Previous literature shows that for digital mental health tools to be successful, the tool must be easy for patients and physicians to use and feasible within existing clinical workflows.
Objective:- This study aims to examine the feasibility of an artificial intelligence–powered CDSS, which combines the operationalized 2016 Canadian Network for Mood and Anxiety Treatments guidelines with a neural network–based individualized treatment remission prediction.
Methods:- Owing to the COVID-19 pandemic, the study was adapted to be completed entirely remotely. A total of 7 physicians recruited outpatients diagnosed with major depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria. Patients completed a minimum of one visit without the CDSS (baseline) and 2 subsequent visits where the CDSS was used by the physician (visits 1 and 2). The primary outcome of interest was change in appointment length after the introduction of the CDSS as a proxy for feasibility. Feasibility and acceptability data were collected through self-report questionnaires and semistructured interviews.
Results:- Data were collected between January and November 2020. A total of 17 patients were enrolled in the study; of the 17 patients, 14 (82%) completed the study. There was no significant difference in appointment length between visits (introduction of the tool did not increase appointment length; F2,24=0.805; mean squared error 58.08; P=.46). In total, 92% (12/13) of patients and 71% (5/7) of physicians felt that the tool was easy to use; 62% (8/13) of patients and 71% (5/7) of physicians rated that they trusted the CDSS. Of the 13 patients, 6 (46%) felt that the patient-clinician relationship significantly or somewhat improved, whereas 7 (54%) felt that it did not change.
Conclusions:- Our findings confirm that the integration of the tool does not significantly increase appointment length and suggest that the CDSS is easy to use and may have positive effects on the patient-physician relationship for some patients. The CDSS is feasible and ready for effectiveness studies
EWOCS-I: The catalog of X-ray sources in Westerlund 1 from the Extended Westerlund 1 and 2 Open Clusters Survey
Context. With a mass exceeding several 104 M and a rich and dense population of massive stars, supermassive young star clusters represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions among stars.Aims. In this paper we present the "Extended Westerlund 1 and 2 Open Clusters Survey" (EWOCS) project, which aims to investigate the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars. The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically, the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec. Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation were carried out using the ACIS-Extract software.Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a photon flux threshold of approximately 2 × 10−8 photons cm−2 s−1. The X-ray sources exhibit a highly concentrated spatial distribution, with 1075 sources located within the central 1 arcminute. We have successfully detected X-ray emissions from 126 out of the 166 known massive stars of the cluster, and we have collected over 71000 photons from the magnetar CXO J164710.20-455217
The CALorimetric Electron Telescope (CALET) for high-energy astroparticle physics on the International Space Station
The CALorimetric Electron Telescope (CALET) is a space experiment, currently under development by Japan in collaboration with Italy and the United States, which will measure the flux of cosmic-ray electrons (and positrons) up to 20 TeV energy, of gamma rays up to 10 TeV, of nuclei with Z from 1 to 40 up to 1 PeV energy, and will detect gamma-ray bursts in the 7 keV to 20 MeV energy range during a 5 year mission. These measurements are essential to investigate possible nearby astrophysical sources of high energy electrons, study the details of galactic particle propagation and search for dark matter signatures. The main detector of CALET, the Calorimeter, consists of a module to identify the particle charge, followed by a thin imaging calorimeter (3 radiation lengths) with tungsten plates interleaving scintillating fibre planes, and a thick energy measuring calorimeter (27 radiation lengths) composed of lead tungstate logs. The Calorimeter has the depth, imaging capabilities and energy resolution necessary for excellent separation between hadrons, electrons and gamma rays. The instrument is currently being prepared for launch (expected in 2015) to the International Space Station ISS, for installation on the Japanese Experiment Module - Exposure Facility (JEM-EF)
ASKAP and MeerKAT surveys of the magellanic clouds
The Magellanic Clouds are a stepping stone from the overwhelming detail of the Milky Way in which we are immersed, to the global characteristics of galaxies both in the nearby and distant universe. They are interacting, gas-rich dwarf galaxies of sub-solar metallicity, not unlike the building blocks that assembled the large galaxies that dominate groups and clusters, and representative of the conditions at the height of cosmic star formation. The Square Kilometre Array (SKA) can make huge strides in understanding galactic metabolism and the ecological processes that govern star formation, by observations of the Magellanic Clouds and other, nearby Magellanic-type irregular galaxies. Two programmes with SKA Pathfinders attempt to pave the way: the approved Galactic ASKAP Spectral Line Survey (GASKAP) includes a deep survey in H I and OH of the Magellanic Clouds, whilst MagiKAT is proposed to perform more detailed studies of selected regions within the Magellanic Clouds - also including Faraday rotation measurements and observations at higher frequencies. These surveys also close the gap with the revolutionizing surveys at far-IR wavelengths with the Spitzer Space Telescope and Herschel Space Observatory
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