624 research outputs found
Real-time phase-shift detection of the surface plasmon resonance
We investigate a method to directly measure the phase of a laser beam
reflected from a metallic film after excitation of surface plasmon polaritons.
This method permits real time access to the phase information, it increases the
possible speed of data acquisition, and it may thus prove useful for increasing
the sensitivity of surface plasmon based sensors
Produção da cenoura e efeito na fertilidade do solo e nutrição decorrente da solarização do solo para controle da tiririca.
Dentre os desafios do cultivo orgânico de hortaliças destaca-se o controle de plantas daninhas, devido à proibição do uso de herbicidas. Entre as invasoras, a tiririca (Cyperus rotundus L.) é de difícil controle pela sua alta competitividade. A solarização é uma alternativa para desinfestação do solo, a qual consiste em cobri-lo com plástico transparente, com bons resultados no controle da tiririca. A fim de avaliar a influência do preparo e do revolvimento do solo sobre a eficiência da solarização no controle da tiririca, bem como seu posterior efeito sobre o cultivo da cenoura, foi realizado um experimento na Fazendinha Agroecológica, em Seropédica (RJ). O experimento foi disposto em blocos ao acaso com três repetições, em arranjo fatorial 2 x 3 mais uma testemunha adicional, sendo: 1) solo solarizado, preparado (com grade aradora) e revolvido 30 dias após a solarização (manualmente com auxílio de uma enxada); 2) solo solarizado, preparado e revolvido aos 60 dias; 3) solo solarizado, preparado e não revolvido; 4) solo solarizado, não preparado e revolvido aos 30 dias; 5) solo solarizado, não preparado e revolvido aos 60 dias; 6) solo solarizado, não preparado e não revolvido; solo não solarizado, não preparado e não revolvido (testemunha). A solarização iniciou-se em 29/1/2002, e durou cem dias. A solarização reduziu em 86% a infestação de tiririca no cultivo da cenoura. Até 10 cm de profundidade, a temperatura do solo foi superior nas parcelas solarizadas, porém a 5 cm, a solarização foi mais eficiente quando associada ao preparo do solo, não havendo efeito do revolvimento. A solarização aumentou os valores da biomassa microbiana e dos teores de Ca, Mg e P do solo. O desenvolvimento da cenoura foi influenciado pela solarização que resultou em maior produtividade
Percolation model for structural phase transitions in LiHIO mixed crystals
A percolation model is proposed to explain the structural phase transitions
found in LiHIO mixed crystals as a function of the
concentration parameter . The percolation thresholds are obtained from Monte
Carlo simulations on the specific lattices occupied by lithium atoms and
hydrogen bonds. The theoretical results strongly suggest that percolating
lithium vacancies and hydrogen bonds are indeed responsible for the solid
solution observed in the experimental range .Comment: 4 pages, 2 figure
Deuteron Electroweak Disintegration
We study the deuteron electrodisintegration with inclusion of the neutral
currents focusing on the helicity asymmetry of the exclusive cross section in
coplanar geometry. We stress that a measurement of this asymmetry in the quasi
elastic region is of interest for an experimental determination of the weak
form factors of the nucleon, allowing one to obtain the parity violating
electron neutron asymmetry. Numerically, we consider the reaction at low
momentum transfer and discuss the sensitivity of the helicity asymmetry to the
strangeness radius and magnetic moment. The problems coming from the finite
angular acceptance of the spectrometers are also considered.Comment: 30 pages, Latex, 7 eps figures, submitted to Phys.Rev.C e-mail:
[email protected] , [email protected]
BASS. XXX. Distribution functions of DR2 Eddington ratios, black hole masses, and X-ray luminosities
Galaxie
Observation of Scaling Violations in Scaled Momentum Distributions at HERA
Charged particle production has been measured in deep inelastic scattering
(DIS) events over a large range of and using the ZEUS detector. The
evolution of the scaled momentum, , with in the range 10 to 1280
, has been investigated in the current fragmentation region of the Breit
frame. The results show clear evidence, in a single experiment, for scaling
violations in scaled momenta as a function of .Comment: 21 pages including 4 figures, to be published in Physics Letters B.
Two references adde
Probing the structure and evolution of BASS active galactic nuclei through Eddington ratios
Galaxie
A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry
Chemotherapeutics tumor resistance is a principal reason for treatment failure, and clinical and experimental data indicate that multidrug transporters such as ATP-binding cassette (ABC) B1 and ABCG2 play a leading role by preventing cytotoxic intracellular drug concentrations. Functional efflux inhibition of existing chemotherapeutics by these pumps continues to present a promising approach for treatment. A contributing factor to the failure of existing inhibitors in clinical applications is limited understanding of specific substrate/inhibitor/pump interactions. We have identified selective efflux inhibitors by profiling multiple ABC transporters against a library of small molecules to find molecular probes to further explore such interactions. In our primary screening protocol using JC-1 as a dual-pump fluorescent reporter substrate, we identified a piperazine-substituted pyrazolo[1,5-a]pyrimidine substructure with promise for selective efflux inhibition. As a result of a focused structure-activity relationship (SAR)-driven chemistry effort, we describe compound 1 (CID44640177), an efflux inhibitor with selectivity toward ABCG2 over ABCB1. Compound 1 is also shown to potentiate the activity of mitoxantrone in vitro as well as preliminarily in vivo in an ABCG2-overexpressing tumor model. At least two analogues significantly reduce tumor size in combination with the chemotherapeutic topotecan. To our knowledge, low nanomolar chemoreversal activity coupled with direct evidence of efflux inhibition for ABCG2 is unprecedented
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