Noise-robust method for image segmentation

Segmentation of noisy images is one of the most challenging problems in image analysis and any improvement of segmentation methods can highly influence the performance of many image processing applications. In automated image segmentation, the fuzzy c-means (FCM) clustering has been widely used because of its ability to model uncertainty within the data, applicability to multi-modal data and fairly robust behaviour. However, the standard FCM algorithm does not consider any information about the spatial linage context and is highly sensitive to noise and other imaging artefacts. Considering above mentioned problems, we developed a new FCM-based approach for the noise-robust fuzzy clustering and we present it in this paper. In this new iterative algorithm we incorporated both spatial and feature space information into the similarity measure and the membership function. We considered that spatial information depends on the relative location and features of the neighbouring pixels. The performance of the proposed algorithm is tested on synthetic image with different noise levels and real images. Experimental quantitative and qualitative segmentation results show that our method efficiently preserves the homogeneity of the regions and is more robust to noise than other FCM-based methods

Fast soliton scattering by delta impurities

We study the Gross-Pitaevskii equation (nonlinear Schroedinger equation) with a repulsive delta function potential. We show that a high velocity incoming soliton is split into a transmitted component and a reflected component. The transmitted mass (L^2 norm squared) is shown to be in good agreement with the quantum transmission rate of the delta function potential. We further show that the transmitted and reflected components resolve into solitons plus dispersive radiation, and quantify the mass and phase of these solitons.Comment: 32 pages, 3 figure

Variability of organic and elemental carbon, water soluble organic carbon, and isotopes in Hong Kong

International audienceTo determine the levels and variations of carbonaceous aerosol in Hong Kong, PM2.5 and PM10 samples were collected by high volume (Hi-vol) samplers at three monitoring stations (representing middle-scale roadside, urban-, and regional-scale environments) during winter (November 2000 to February 2001) and summer (June 2001 to August 2001) periods. The highest concentrations of organic carbon (OC), elemental carbon (EC), and water-soluble organic carbon (WSOC) were found at the middle-scale roadside site with the lowest at the regional-scale site. The percentages of WSOC in total carbon at these sites were inversely correlated with their concentrations (i.e., the highest percentages of WSOC were observed at the regional-scale site). A high WSOC fraction may be associated with aged aerosol because of the secondary formation by photochemical oxidation of organic precursors of anthropogenic pollutants during transport. The annual average of isotope abundances (?13C) of OC and EC were ?26.9±0.5? and ?25.6±0.1?, respectively. There were no notable differences for seasonal distributions of carbon isotopic composition, consistent with motor vehicle emissions being the main source contributors of carbonaceous aerosol in Hong Kong. OC 13C abundances at the regional-scale site were higher than those at the middle-scale roadside and urban sites, consistent with secondary organic aerosols of biogenic origin

The Glycemic, Cholesterol, and Weight Effects of L-carnitine in Diabetes: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Introduction L-carnitine possibly impacts insulin sensitivity and glucose metabolism. However, its therapeutic role in diabetes is poorly understood. Methods A systematic review and meta-analysis were conducted using PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) from inception through June 30, 2021. Included studies evaluated the use of L-carnitine in diabetes on fasting blood glucose (FBG), hemoglobin A1c (HbA1c), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), weight, or body mass index (BMI). Weighted mean difference (WMD) and 95% confidence intervals (CI) were calculated using the DerSimonian and Laird random-effects model. Results Seventeen studies involving 1622 patients were included. Reductions in FBG (WMD = -0.46 mmol/L, 95% CI = -0.68 to -0.23 mmol/L), HbA1c (WMD = -0.5%, 95% CI = -0.8 to -0.1%), TC (WMD = -0.29 mmol/L, 95% CI = -0.42 to -0.16 mmol/L), and LDL-C (WMD = -0.23 mmol/L, 95% CI = -0.39 to -0.07 mmol/L) were significant. Effects on HDL-C, TG, weight, or BMI were insignificant. Doses between 1001 to 2000 mg showed greatest benefit (p \u3c 0.02 for all). Discussion/Conclusion L-carnitine plays a potential role as adjunctive therapy in diabetes. Additional research is necessary for patients with higher baseline HbA1c and type 1 diabetes

Glycosaminoglycans and other sulphated polysaccharides in calculogenesis of urinary stones

Naturally occurring glycosaminoglycans (GAGs) and other, semisynthetic, sulphated polysaccharides are thought to play an important role in urolithiasis. Processes involved in urinary stone formation are crystallization and crystal retention. Oxalate transport and renal tubular cell injury are determining factors in these processes. In this article experimental results concerning the possible mechanisms of action of GAGs and other sulphated polysaccharides are reviewed. GAGs are inhibitors of crystal growth and agglomeration and possibly also of nucleation. They can prevent crystal adherence, correct an abnormal oxalate flux and prevent renal tubular cell damage

Modified Norris–Landzberg Model and Optimum Design of Temperature Cycling ALT

Accelerated life testing (ALT) is an effective way to assess the lifetime of a product. Due to the complex nature of its testing profile, it is difficult to carry out temperature cycling ALT. This paper establishes a modified Norris–Landzberg model as acceleration model, and proposes the optimum design method of temperature cycling ALT. First, the FEA method is used to study the influence of temperature cycling profile parameters on the thermal fatigue life of 63Sn–37Pb solder joints. Then, a modified Norris–Landzberg model is proposed by introducing ramp time and dwell time with an added weight value. Finally, the temperature cycling ALT is regarded as a special multi-stress ALT to study its optimum design method. The uniform design theory is used to determine the combined mode. The optimum model is established with the objective of minimizing the asymptotic variance of the estimation of median lifetime under normal use conditions, and the simulation example shows the workability of the proposed method

Towards a global analysis of polarized parton distributions

We present a technique for implementing in a fast way, and without any approximations, higher-order calculations of partonic cross sections into global analyses of parton distribution functions. The approach, which is set up in Mellin-moment space, is particularly suited for analyses of future data from polarized proton-proton collisions, but not limited to this case. The usefulness and practicability of this method is demonstrated for the semi-inclusive production of hadrons in deep-inelastic scattering and the transverse momentum distribution of ``prompt'' photons in pp collisions, and a case study for a future global analysis of polarized parton densities is presented.Comment: 20 pages, LaTeX, 6 eps figures, final version to appear in PRD (minor changes

Allergenicity and oral tolerance of enzymatic cross-linked tropomyosin evaluated using cell and mouse models

The enzymatic cross-linking of proteins to form high-molecular-weight compounds may alter their sensitization potential. The IgG-/IgE-binding activity, digestibility, allergenicity, and oral tolerance of cross-linked tropomyosin with tyrosinase (CTC) or horseradish peroxidase (CHP) were investigated. ELISA results demonstrated CTC or CHP reduced its IgE-binding activity by 34.5 ± 1.8 and 63.5 ± 0.6%, respectively. Compared with native tropomyosin or CTC, CHP was more easily digested into small fragments; CHP decreased the degranulation of RBL-2H3 cells and increased endocytosis by dendritic cells. CHP can induce oral tolerance and reduce allergenicity in mice by decreasing IgE and IgG1 levels in serum, the production of T-cell cytokines, and the percentage composition of dendritic cells. These findings demonstrate CHP has more potential of reducing the allergenicity than CTC via influencing the morphology of protein, changing the original method of antigen presentation, modulating the Th1/Th2 immunobalance, and inducing the oral tolerance of the allergen tropomyosin