On the Stability and the Approximation of Branching Distribution Flows, with Applications to Nonlinear Multiple Target Filtering

We analyse the exponential stability properties of a class of measure-valued equations arising in nonlinear multi-target filtering problems. We also prove the uniform convergence properties w.r.t. the time parameter of a rather general class of stochastic filtering algorithms, including sequential Monte Carlo type models and mean eld particle interpretation models. We illustrate these results in the context of the Bernoulli and the Probability Hypothesis Density filter, yielding what seems to be the first results of this kind in this subject

A continuous non-linear shadowing model of columnar growth

We propose the first continuous model with long range screening (shadowing) that described columnar growth in one space dimension, as observed in plasma sputter deposition. It is based on a new continuous partial derivative equation with non-linear diffusion and where the shadowing effects apply on all the different processes.Comment: Fast Track Communicatio

Static behaviour of functionally graded sandwich beams using a quasi-3D theory

This paper presents static behaviour of functionally graded (FG) sandwich beams by using a quasi-3D theory, which includes both shear deformation and thickness stretching effects. Various symmetric and non-symmetric sandwich beams with FG material in the core or skins under the uniformly distributed load are considered. Finite element model (FEM) and Navier solutions are developed to determine the displacement and stresses of FG sandwich beams for various power-law index, skin-core-skin thickness ratios and boundary conditions. Numerical results are compared with those predicted by other theories to show the effects of shear deformation and thickness stretching on displacement and stresses

Progressive metabolic impairment underlies the novel nematicidal action of fluensulfone on the potato cyst nematode Globodera pallida

Background: Fluensulfone is a new nematicide with an excellent profile of selective toxicity against plant parasitic nematodes. Here, its effects on the physiology and biochemistry of the potato cyst nematode Globodera pallida have been investigated and comparisons made with its effect on the life-span of the free-living nematode Caenorhabditis elegans to provide insight into its mode of action and its selective toxicity. Results: Fluensulfone exerts acute effects (≤ 1 h; ≥ 100 μM) on stylet thrusting and motility of hatched second stage G. pallida juveniles (J2s). Chronic exposure to lower concentrations of fluensulfone (≥ 3 days; ≤ 30 μM), reveals a slowly developing metabolic insult in which G. pallida J2s sequentially exhibit a reduction in motility, loss of a metabolic marker for cell viability, high lipid content and tissue degeneration prior to death. These effects are absent in adults and dauers of the model genetic nematode Caenorhabditis elegans. Conclusion: The nematicidal action of fluensulfone follows a time-course which progresses from an early impact on motility through to an accumulating metabolic impairment, an inability to access lipid stores and death

Missing-in-metastasis and IRSp53 deform PI(4,5)P-2-rich membranes by an inverse BAR domain-like mechanism

The actin cytoskeleton plays a fundamental role in various motile and morphogenetic processes involving membrane dynamics. We show that actin-binding proteins MIM (missing-in-metastasis) and IRSp53 directly bind PI(4,5)P-2-rich membranes and deform them into tubular structures. This activity resides in the N-terminal IRSp53/MIM domain (IMD) of these proteins, which is structurally related to membrane-tubulating BAR (Bin/amphiphysin/Rvs) domains. We found that because of a difference in the geometry of the PI(4,5)P-2-binding site, IMDs induce a membrane curvature opposite that of BAR domains and deform membranes by binding to the interior of the tubule. This explains why IMD proteins induce plasma membrane protrusions rather than invaginations. We also provide evidence that the membrane-deforming activity of IMDs, instead of the previously proposed F-actin - bundling or GTPase-binding activities, is critical for the induction of the filopodia/microspikes in cultured mammalian cells. Together, these data reveal that interplay between actin dynamics and a novel membrane-deformation activity promotes cell motility and morphogenesis

DIAMS revisited: Taming the variety of knowledge in fault diagnosis expert systems

The DIAMS program, initiated in 1986, led to the development of a prototype expert system, DIAMS-1 dedicated to the Telecom 1 Attitude and Orbit Control System, and to a near-operational system, DIAMS-2, covering a whole satellite (the Telecom 2 platform and its interfaces with the payload), which was installed in the Satellite Control Center in 1993. The refinement of the knowledge representation and reasoning is now being studied, focusing on the introduction of appropriate handling of incompleteness, uncertainty and time, and keeping in mind operational constraints. For the latest generation of the tool, DIAMS-3, a new architecture has been proposed, that enables the cooperative exploitation of various models and knowledge representations. On the same baseline, new solutions enabling higher integration of diagnostic systems in the operational environment and cooperation with other knowledge intensive systems such as data analysis, planning or procedure management tools have been introduced

The evolution operator of the Hartree-type equation with a quadratic potential

Based on the ideology of the Maslov's complex germ theory, a method has been developed for finding an exact solution of the Cauchy problem for a Hartree-type equation with a quadratic potential in the class of semiclassically concentrated functions. The nonlinear evolution operator has been obtained in explicit form in the class of semiclassically concentrated functions. Parametric families of symmetry operators have been found for the Hartree-type equation. With the help of symmetry operators, families of exact solutions of the equation have been constructed. Exact expressions are obtained for the quasi-energies and their respective states. The Aharonov-Anandan geometric phases are found in explicit form for the quasi-energy states.Comment: 23 pege

Imaging and Treatment of Patients with Acute Stroke: An Evidence-Based Review

Evidence-based medicine has emerged as a valuable tool to guide clinical decision-making, by summarizing the best possible evidence for both diagnostic and treatment strategies. Imaging plays a critical role in the evaluation and treatment of patients with acute ischemic stroke, especially those who are being considered for thrombolytic or endovascular therapy. Time from stroke-symptom onset to treatment is a strong predictor of long-term functional outcome after stroke. Therefore, imaging and treatment decisions must occur rapidly in this setting, while minimizing unnecessary delays in treatment. The aim of this review was to summarize the best available evidence for the diagnostic and therapeutic management of patients with acute ischemic stroke

The Drift Chambers Of The Nomad Experiment

We present a detailed description of the drift chambers used as an active target and a tracking device in the NOMAD experiment at CERN. The main characteristics of these chambers are a large area, a self supporting structure made of light composite materials and a low cost. A spatial resolution of 150 microns has been achieved with a single hit efficiency of 97%.Comment: 42 pages, 26 figure

Superdeformed rotational bands in the Mercury region; A Cranked Skyrme-Hartree-Fock-Bogoliubov study

A study of rotational properties of the ground superdeformed bands in \Hg{0}, \Hg{2}, \Hg{4}, and \Pb{4} is presented. We use the cranked Hartree-Fock-Bogoliubov method with the {\skm} parametrization of the Skyrme force in the particle-hole channel and a seniority interaction in the pairing channel. An approximate particle number projection is performed by means of the Lipkin-Nogami prescription. We analyze the proton and neutron quasiparticle routhians in connection with the present information on about thirty presently observed superdeformed bands in nuclei close neighbours of \Hg{2}.Comment: 26 LaTeX pages, 14 uuencoded postscript figures included, Preprint IPN-TH 93-6