Successful management of peri-implantitis around short and ultrashort single-crown implants: a case series with a 3-year follow-up

Introduction and Aim. In case of peri-implantitis, resective surgery is contraindicated for short and ultrashort implants, limiting the treatment options to regenerative surgery or to implant removal. 'is retrospective case series presents the clinical and radiographic outcomes of a surgical regenerative procedure to treat peri-implantitis around short and ultrashort implants. Materials and Methods. The study is a retrospective evaluation of patients suffering from peri-implantitis and those who underwent access flap surgery, concomitant chemical and mechanical decontamination of implant surface, and bone grafting using a self-hardening mixture of bone substitutes and biphasic calcium sulfate. No membranes were applied to cover the grafting material, and primary tension-free closure was achieved. The retrospective protocol was reviewed and approved by the Ethics Committee for Clinical Sperimentation (CESC) of Verona and Rovigo, Italy (based in the University of Verona) (Prog. 1863CESC. Date of approval: 2018-07-04). Results. 15 patients (17 implants) have been diagnosed with peri-implantitis after a mean follow-up of 24 months after loading. Implant length was between 5 and 8 mm. 8 patients (10 implants) had a history of periodontitis. At baseline, the mean PD (probing pocket dept) at the deepest site was 8.12 mm, with an average mBI (modified bleeding index) of 2.35 and a mean BD (bone defect depth) of 3.04 mm. At the 3-year follow-up, the CSR was 100%, the mean mBI was 0.88 (average reduction: - 1.47), the mean PD was 3.35 mm (mean PD reduction: 4.77 mm), and the mean bone defect was reduced by 1.74 mm, with a mean bone fill of 55%. Conclusions. The results of the present case series suggest that if accurate surface decontamination is achieved, high survival rate and good clinical and radiographic results can be obtained after 3 years. However, only the histological examination could confirm the growth of new bone in direct contact with the implant surface or if the grafted material only fills the space left by the peri-implant defect

Understanding bottom-up continuous hydrothermal synthesis of nanoparticles using empirical measurement and computational simulation

Continuous hydrothermal synthesis was highlighted in a recent review as an enabling technology for the production of nanoparticles. In recent years, it has been shown to be a suitable reaction medium for the synthesis of a wide range of nanomaterials. Many single and complex nanomaterials such as metals, metal oxides, doped oxides, carbonates, sulfides, hydroxides, phosphates, and metal organic frameworks can be formed using continuous hydrothermal synthesis techniques. This work presents a methodology to characterize continuous hydrothermal flow systems both experimentally and numerically, and to determine the scalability of a counter current supercritical water reactor for the large scale production (>1,000 T·year–1) of nanomaterials. Experiments were performed using a purpose-built continuous flow rig, featuring an injection loop on a metal salt feed line, which allowed the injection of a chromophoric tracer. At the system outlet, the tracer was detected using UV/Vis absorption, which could be used to measure the residence time distribution within the reactor volume. Computational fluid dynamics (CFD) calculations were also conducted using a modeled geometry to represent the experimental apparatus. The performance of the CFD model was tested against experimental data, verifying that the CFD model accurately predicted the nucleation and growth of the nanomaterials inside the reactor

Assessing the life cycle environmental impacts of titania nanoparticle production by continuous flow solvo/hydrothermal synthesis

Continuous-flow hydrothermal and solvothermal syntheses offer substantial advantages over conventional processes, producing high quality materials from a wide range of precursors. In this study, we evaluate the “cradle-to-gate” life cycle environmental impacts of alternative titanium dioxide (TiO₂) nanoparticle production parameters, considering a range of operational conditions, precursors, material properties and production capacities. A detailed characterisation of the nano-TiO₂ products allows us, for the first time, to link key nanoparticle characteristics to production parameters and environmental impacts, providing a useful foundation for future studies evaluating nano-TiO₂ applications. Five different titanium precursors are considered, ranging from simple inorganic precursors, like titanium oxysulphate (TiOS), to complex organic precursors such as titanium bis(ammonium-lactato)dihydroxide (TiBALD). Synthesis at the laboratory scale is used to determine the yield, size distribution, crystallinity and phase of the nanoparticles. The specifications and operating experience of a full scale plant (>1000 t per year) are used to estimate the mass and energy inputs of industrial scale production for the life cycle assessment. Overall, higher process temperatures are linked to larger, more crystalline nanoparticles and higher conversion rates. Precursor selection also influences nano-TiO₂ properties: production from TiOS results in the largest particle sizes, while TiBALD achieves the smallest particles and narrowest size distribution. Precursor selection is the main factor in determining cradle-to-gate environmental impacts (>80% in some cases), due to the production impact of complex organic precursors. Nano-TiO2 production from TiOS shows the lowest global warming potential (GWP) (<12 kg CO₂-eq. per kg TiO₂) and cumulative energy demand (CED) (<149 MJ kg¯¹ TiO₂) due to the low environmental impact of the precursor, the use of water as a solvent and its high yield even at lower temperatures. Conversely, the TiBALD precursor shows the highest impact (86 kg CO₂-eq. per kg TiO₂ and 1952 MJ kg¯¹ TiO₂) due to the need for additional post-synthesis steps and complexity of precursor manufacturing. The main purpose of this study is not a direct comparison of the environmental impacts of TiO₂ nanoparticles manufactured utilizing various precursors under different conditions, but to provide an essential foundation for future work evaluating potential applications of nano-TiO₂ and their life cycle environmental impacts

UVaEjector: CFD modelling of refrigerant ejectors

This dataset comprises an ANSYS Workbench file in compressed format. Such file contains all the simulation setup and results used by the authors in its submission to Energy Journal

UVaEjector: CFD modelling of refrigerant ejectors

This dataset comprises an ANSYS Workbench file in compressed format. Such file contains all the simulation setup and results used by the authors in its submission to Energy Journal.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

Quantification of mixing efficiency in turbulent supercritical water hydrothermal reactors

This paper presents a mathematical model able to quantify mixing efficiency in Supercritical Water Hydrothermal Reactors (SWHR) for the production of different types of nanoparticles. In fact, mixing plays a crucial role in determining the final particle size distribution and therefore the final product quality. In this work, mixing of supercritical water streams is studied with Computational Fluid Dynamics (CFD) by using the Reynolds Averaged Navier Stokes (RANS) approach coupled with an equation of state and a micromixing model, to take into account the effect of molecular mixing. The performance of the model is investigated in three different scenarios, corresponding to very different values of the Richardson number and very different mixer configurations. The main results show how mixing can be quantified by means of a global mixing time and how turbulence enhances the process, leading to better final product characteristics, especially in terms of lower mean particle size and narrower particle size distributions. This confirms previous research on this topic, highlighting the fact that both the mean particle size and the particle size distribution are strongly dependent on the mixing features of the SWH

Velocity measurements in a model of a coronary bifurcation with stent. Numerical benchmark (Database) BIO-17-1458

Experimental measurements for several stenting techniques under steady and unsteady flow conditions were performed. The test conditions were highly controlled and uncertainty was accurately predicted. The results obtained in this research consist of readily accessible, easy to emulate, detailed velocity fields and geometry.<div><br></div><div>This dataset is explained and commented in:</div><div>Carrascal, P. G., García, J. G., Pallares, J. S., Ruiz, F. C., & Martín, F. M. (2018). Benchmark for numerical models of stented coronary bifurcation flow. <i>Journal of biomechanical engineering</i>, <i>140</i>(9), 091009.<br></div

Successful Management of Peri-Implantitis around Short and Ultrashort Single-Crown Implants: A Case Series with a 3-Year Follow-Up

Introduction and Aim. In case of peri-implantitis, resective surgery is contraindicated for short and ultrashort implants, limiting the treatment options to regenerative surgery or to implant removal. This retrospective case series presents the clinical and radiographic outcomes of a surgical regenerative procedure to treat peri-implantitis around short and ultrashort implants. Materials and Methods. The study is a retrospective evaluation of patients suffering from peri-implantitis and those who underwent access flap surgery, concomitant chemical and mechanical decontamination of implant surface, and bone grafting using a self-hardening mixture of bone substitutes and biphasic calcium sulfate. No membranes were applied to cover the grafting material, and primary tension-free closure was achieved. The retrospective protocol was reviewed and approved by the Ethics Committee for Clinical Sperimentation (CESC) of Verona and Rovigo, Italy (based in the University of Verona) (Prog. 1863CESC. Date of approval: 2018-07-04). Results. 15 patients (17 implants) have been diagnosed with peri-implantitis after a mean follow-up of 24 months after loading. Implant length was between 5 and 8 mm. 8 patients (10 implants) had a history of periodontitis. At baseline, the mean PD (probing pocket dept) at the deepest site was 8.12 mm, with an average mBI (modified bleeding index) of 2.35 and a mean BD (bone defect depth) of 3.04 mm. At the 3-year follow-up, the CSR was 100%, the mean mBI was 0.88 (average reduction: -1.47), the mean PD was 3.35 mm (mean PD reduction: 4.77 mm), and the mean bone defect was reduced by 1.74 mm, with a mean bone fill of 55%. Conclusions. The results of the present case series suggest that if accurate surface decontamination is achieved, high survival rate and good clinical and radiographic results can be obtained after 3 years. However, only the histological examination could confirm the growth of new bone in direct contact with the implant surface or if the grafted material only fills the space left by the peri-implant defect