146 research outputs found
The Effect Of Perpetrator Remorse, Victim Gender, And Photographer On Victim Blame In A Case Of Nonconsensual Photograph Sharing
Emotional expression is often used as a way to determine a personâs intent for social situations. In a courtroom, when a perpetrator expresses (or fails to express) remorse, not only the perception of the perpetrator may be altered, but also the perception of the victim. This difference may especially be the case in a situation where the victim is viewed as having a high level of culpability for the crime, such as if the victim took the picture and sent it. Furthermore, the gender of the victim of the crime may influence how the victim is perceived, such that women may be viewed as more culpable for their victimization than men. In recent years, an increase in technology use has led to an increase in cyber-crimes. Although some states have passed laws in an attempt to police these crimes, many states have been unable to keep up with the occurrence of these new crimes. One of these cyber-crimes is when a nude photograph of an individual is shared on the Internet without the pictured personâs consent, which is also known as nonconsensual pornography. Victims of nonconsensual pornography may face problems such as stalking, harassment, job loss, and depression. When perpetrators are assigned a punishment for this crime, perceptions of the situation may impact the outcome of the trial. The current study examined the impact of remorse, victim gender, and victim culpability on both victim and perpetrator blame in a case of nonconsensual pornography. Results indicated victims are blamed less and the perpetrators are blamed more in the remorse condition when compared to the control condition. Additionally, the victim was attributed more blame when he or she took the photograph than when the perpetrator took the photo. Lastly, Men were more likely than women to blame the victim. Implications and future directions are discussed
Expert Testimony in Cases Involving Battered Women Who Kill: Going Beyond the Battered Woman Syndrome
IFKIS - a basis for managing avalanche risk in settlements and on roads in Switzerland
After the avalanche winter of 1999 in Switzerland, which caused 17 deaths and damage of over CHF 600 mill. in buildings and on roads, the project IFKIS, aimed at improving the basics of organizational measures (closure of roads, evacuation etc.) in avalanche risk management, was initiated. <P style='line-height: 20px;'> The three main parts of the project were the development of a compulsory checklist for avalanche safety services, a modular education and training course program and an information system for safety services. The information system was developed in order to improve both the information flux between the national centre for avalanche forecasting, the Swiss Federal Institute for Snow and Avalanche Research SLF, and the local safety services on the one hand and the communication between avalanche safety services in the communities on the other hand. <P style='line-height: 20px;'> The results of this project make a valuable contribution to strengthening organizational measures in avalanche risk management and to closing the gaps, which became apparent during the avalanche winter of 1999. They are not restricted to snow avalanches but can also be adapted for dealing with other natural hazard processes and catastrophes
Making SDGs work for climate change hotspots
The impacts of climate change on people's livelihoods have been widely documented. It is expected that climate and environmental change will hamper poverty reduction, or even exacerbate poverty in some or all of its dimensions. Changes in the biophysical environment, such as droughts, flooding, water quantity and quality, and degrading ecosystems, are expected to affect opportunities for people to generate income. These changes, combined with a deficiency in coping strategies and innovation to adapt to particular climate change threats, are in turn likely to lead to increased economic and social vulnerability of households and communities, especially amongst the poorest
The effect of communication between the right and left liver on the outcome of surgical drainage for jaundice due to malignant obstruction at the hilus of the liver
Debate continues regarding the optimal management of irresectable malignant proximal biliary obstruction. Controversy exists concerning the ability of unilateral drainage to provide adequate biliary decompression with tumors that have occluded the communication between the right and left hepatic ductal systems. Between October 1986 and October 1989, 18 patients with malignant proximal biliary obstruction were treated by an intrahepatic biliary enteric bypass. Patients were divided into two groups based on the presence or absence of a communication between the right and left biliary systems. In Group I (n = 9), there was free communication; and in Group II (n = 9) there was no communication. There were two perioperative deaths (11%) one due to persistent cholangitis and the other to myocardial insufficiency both with one death in each group. The median survival (excluding perioperative deaths) was 5.6 months. Comparison of pre- and postoperative serum levels of bilirubin and alkaline phosphatase showed a significant decrease in each group, but no difference between the groups in the size of the reduction. Sixteen patients survived at least three months and the palliation was judged as excellent in eight, fair in five, and unchanged in three. These results demonstrate the effectiveness of biliary enteric bypass regardless of communication between the left and right biliary ductal systems.H. U. Baer, M. Rhyner, S. C. Stain, P. W. Glauser, A. R. Dennison, G. J. Maddern, and L. H. Blumgar
Transport on percolation clusters with power-law distributed bond strengths: when do blobs matter?
The simplest transport problem, namely maxflow, is investigated on critical
percolation clusters in two and three dimensions, using a combination of
extremal statistics arguments and exact numerical computations, for power-law
distributed bond strengths of the type .
Assuming that only cutting bonds determine the flow, the maxflow critical
exponent \ve is found to be \ve(\alpha)=(d-1) \nu + 1/(1-\alpha). This
prediction is confirmed with excellent accuracy using large-scale numerical
simulation in two and three dimensions. However, in the region of anomalous
bond capacity distributions () we demonstrate that, due to
cluster-structure fluctuations, it is not the cutting bonds but the blobs that
set the transport properties of the backbone. This ``blob-dominance'' avoids a
cross-over to a regime where structural details, the distribution of the number
of red or cutting bonds, would set the scaling. The restored scaling exponents
however still follow the simplistic red bond estimate. This is argued to be due
to the existence of a hierarchy of so-called minimum cut-configurations, for
which cutting bonds form the lowest level, and whose transport properties scale
all in the same way. We point out the relevance of our findings to other scalar
transport problems (i.e. conductivity).Comment: 9 pages + Postscript figures. Revtex4+psfig. Submitted to PR
What static and dynamic properties should slalom skis possess? Judgments by advanced and expert skiers
Flexural and torsional rigidity are important properties of skis. However, the flexural and torsional rigidity that lead to optimal performance remain to be established. In the present study, four pairs of slalom skis that differed in flexural and torsional rigidity were tested by advanced and expert skiers. Using a 10-item questionnaire, different aspects of the skisâ performance were rated on a 9-point scale. For each pair of skis, physical measurements were compared with the ratings of the two groups of skiers. Correlations (Spearman) were then determined between (i) different mechanical properties of the skis (static and dynamic), (ii) subjective assessments of the participants, and (iii) properties of the skis and the participantsâ assessments. The latter showed that expert skiers rate the aspects of the skis more accurately than advanced skiers. Importantly, expert skiers are particularly sensitive to torsion of the skis. These results suggest that such highly rated elements should be addressed in future ski designs
Novel in vitro diagnosis of equine allergies using a protein array and mathematical modelling approach: a proof of concept using insect bite hypersensitivity
Insect bite hypersensitivity (IBH) is a seasonal recurrent skin allergy of horses caused by IgE-mediated reactions to allergens present in the saliva of biting insects of the genus Culicoides, and possibly also Simulium and Stomoxys species. In this work we show that protein microarrays containing complex extracts and pure proteins, including recombinant Culicoides allergens, can be used as a powerful technique for the diagnosis of IBH. Besides the obvious advantages such as general profiling and use of few microliters of samples, this microarray technique permits automation and allows the generation of mathematical models with the calculation of individual risk profiles that can support the clinical diagnosis of allergic diseases. After selection of variables on influence on the projection (VIP), the observed values of sensitivity and specificity were 1.0 and 0.967, respectively. This confirms the highly discriminatory power of this approach for IBH and made it possible to attain a robust predictive mathematical model for this disease. It also further demonstrates the specificity of the protein array method on identifying a particular IgE-mediated disease when the sensitising allergen group is known
Stateâofâtheâart in marketed adjuvants and formulations in Allergen Immunotherapy: a position paper of the European Academy of Allergy and Clinical Immunology (EAACI)
Since the introduction of allergen immunotherapy (AIT) over 100 years ago, focus has been on standardization of allergen extracts, with reliable molecular composition of allergens receiving the highest attention. While adjuvants play a major role in European AIT, they have been less well studied. In this Position Paper we summarize current unmet needs of adjuvants in AIT citing current evidence. Four adjuvants are used in products marketed in Europe: aluminium hydroxide (Al(OH)3) is the most frequently used adjuvant, with microcrystalline tyrosine (MCT), monophosphoryl lipid A (MPLA) and calcium phosphate (CaP) used less frequently. Recent studies on humans, and using mouse models, have characterized in part the mechanisms of action of adjuvants on preâexisting immune responses. AIT differs from prophylactic vaccines that provoke immunity to infectious agents, as in allergy the patient is preâsensitized to the allergen. The intended mode of action of adjuvants is to simultaneously enhance the immunogenicity of the allergen, while precipitating the allergen at the injection site to reduce the risk of anaphylaxis. Contrasting immune effects are seen with different adjuvants. Aluminium hydroxide initially boosts Th2 responses, while the other adjuvants utilised in AIT redirect the Th2 immune response toward Th1 immunity. After varying lengths of time, each of the adjuvants supports tolerance. Further studies of the mechanisms of action of adjuvants may advise shorter treatment periods than the current threeâtoâfiveâyear regimens, enhancing patient adherence. Improved lead compounds from the adjuvant pipeline are under development and are explored for their capacity to fill this unmet need
Semi-automated Magnetic Bead-Based Antibody Selection from Phage Display Libraries
Phage display of combinatorial antibody libraries is a very efficient method for selecting recombinant antibodies against a wide range of molecules. It has been applied very successfully for the generation of therapeutic antibodies for more than a decade. To increase robustness and reproducibility of the selection procedure, we developed a semi-automated selection method for the generation of recombinant antibodies from phage display libraries. In this procedure, the selection targets are specifically immobilised to magnetic particles which can then by automatically handled by a magnetic particle processor. At present up to 96 samples can be handled simultaneously. Applying the processor allows standardisation of panning parameters such as washing conditions, incubation times, or to perform parallel selections on same targets under different buffer conditions. Additionally, the whole protocol has been streamlined to carry out bead loading, phage selection, phage amplification between selection rounds and magnetic particle ELISA for confirmation of binding activity in microtiter plate formats. Until now, this method has been successfully applied to select antibody fragments against different types of target, such as peptides, recombinant or homologous proteins, or chemical compounds
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