Overcoming Thermo-Optical Dynamics in Broadband Nanophotonic Sensing

Advances in integrated photonics open exciting opportunities for batch-fabricated optical sensors using high quality factor nanophotonic cavities to achieve ultra-high sensitivities and bandwidths. The sensitivity improves with higher optical power, however, localized absorption and heating within a micrometer-scale mode volume prominently distorts the cavity resonances and strongly couples the sensor response to thermal dynamics, limiting the sensitivity and hindering the measurement of broadband time-dependent signals. Here, we derive a frequency-dependent photonic sensor transfer function that accounts for thermo-optical dynamics and quantitatively describes the measured broadband optomechanical signal from an integrated photonic atomic-force-microscopy nanomechanical probe. Using this transfer function, the probe can be operated in the high optical power, strongly thermo-optically nonlinear regime, reaching a sensitivity of $\approx$ 0.4 fm/Hz$^{1/2}$, an improvement of $\approx 10\times$ relative to the best performance in the linear regime. Counterintuitively, we discover that higher transduction gain and sensitivity are obtained with lower quality factor optical modes for low signal frequencies. Not limited to optomechanical transducers, the derived transfer function is generally valid for describing small-signal dynamic response of a broad range of technologically important photonic sensors subject to the thermo-optical effect

Endurance of quantum coherence due to particle indistinguishability in noisy quantum networks

Quantum coherence, the physical property underlying fundamental phenomena such as multi-particle interference and entanglement, has emerged as a valuable resource upon which modern technologies are founded. In general, the most prominent adversary of quantum coherence is noise arising from the interaction of the associated dynamical system with its environment. Under certain conditions, however, the existence of noise may drive quantum and classical systems to endure intriguing nontrivial effects. In this vein, here we demonstrate, both theoretically and experimentally, that when two indistinguishable non-interacting particles co-propagate through quantum networks affected by non-dissipative noise, the system always evolves into a steady state in which coherences accounting for particle indistinguishabilty perpetually prevail. Furthermore, we show that the same steady state with surviving quantum coherences is reached even when the initial state exhibits classical correlations.Comment: arXiv admin note: substantial text overlap with arXiv:1709.0433

Effects of mergers and galaxy interactions at intermediate densities in the SDSS-DR4

Recently, several observational works have provided evidence in favor of a pre-processing of galaxies at moderate environments. These evidences show that the transition of galaxies onto the red-sequence could take place in galaxy groups in the outskirt of clusters or in the infalling populations. Based on the evidence that interacting and merging systems are priviledged found at intermediate densities, we use the SDSSDR4 data to analyse the role of mergers and close galaxy interactions as environmental processes to lead to evolutionary transformations. We explore the properties of galaxy pairs and merging systems at different local and global density environments, comparing them with those of isolated galaxies in an unbiased control sample.Recientemente varios autores han aportado evidencia observacional que sugerir´ıa que las galaxias son pre-procesadas en regiones de densidad intermedia, produciendo una gran transformacion en las mismas. Estos resultados observacionales muestran que la transicion de las galaxias hacia la secuencia roja se producir´ıa en regiones perifericas de los cumulos de galaxias. Por otra parte, existe evidencia tanto teorica como observacional que indicar´ıa que las interacciones y fusiones de galaxias son particularmente frecuentes en estas regiones. En este trabajo analizamos el rol de las interacciones y colisiones de galaxias en regiones de densidad intermedia, utilizando para tal efecto galaxias del cat´alogo SDSS-DR4.Fil: Perez, J.. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Tissera, Patricia Beatriz. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Padilla, N.. Pontificia Universidad Católica de Chile; ChileFil: Alonso, S.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Complejo Astronómico "el Leoncito". Universidad Nacional de Córdoba. Complejo Astronómico "el Leoncito". Universidad Nacional de la Plata. Complejo Astronómico "el Leoncito". Universidad Nacional de San Juan. Complejo Astronómico "el Leoncito"; ArgentinaFil: Garcia Lambas, Diego Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomia Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomia Teórica y Experimental; Argentin

The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism

The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer, summer days, suggesting an underlying link between circadian biology and the melanocortin system. Despite key neuroanatomical substrates shared by both circadian and melanocortin-signaling pathways, little is known about the relationship between the two. Here we identify a link between circadian disruption and the control of glucose homeostasis mediated through the melanocortin-4 receptor (Mc4r). Mc4r-deficient mice exhibit exaggerated circadian fluctuations in baseline blood glucose and glucose tolerance. Interestingly, exposure to lighting conditions that disrupt circadian rhythms improve their glucose tolerance. This improvement occurs through an increase in glucose clearance by skeletal muscle and is food intake and body weight independent. Restoring Mc4r expression to the paraventricular nucleus prevents the improvement in glucose tolerance, supporting a role for the paraventricular nucleus in the integration of circadian light cues and metabolism. Altogether these data suggest that Mc4r signaling plays a protective role in minimizing glucose fluctuations due to circadian rhythms and environmental light cues and demonstrate a previously undiscovered connection between circadian biology and glucose metabolism mediated through the melanocortin system

Solving the Physical Traveling Salesman Problem: Tree Search and Macro Actions

This paper presents a number of approaches for solving a real-time game consisting of a ship that must visit a number of waypoints scattered around a 2-D maze full of obstacles. The game, the Physical Traveling Salesman Problem (PTSP), which featured in two IEEE conference competitions during 2012, provides a good balance between long-term planning (finding the optimal sequence of waypoints to visit), and short-term planning (driving the ship in the maze). This paper focuses on the algorithm that won both PTSP competitions: it takes advantage of the physics of the game to calculate the optimal order of waypoints, and it employs Monte Carlo tree search (MCTS) to drive the ship. The algorithm uses repetitions of actions (macro actions) to reduce the search space for navigation. Variations of this algorithm are presented and analyzed, in order to understand the strength of each one of its constituents and to comprehend what makes such an approach the best controller found so far for the PTSP. © 2009-2012 IEEE

The Good, the Bad, and the Ugly: Statistical quality assessment of SZ detections

International audienceWe examine three approaches to the problem of source classification in catalogues. Our goal is to determine the confidence withwhich the elements in these catalogues can be distinguished in populations on the basis of their spectral energy distribution (SED).Our analysis is based on the projection of the measurements onto a comprehensive SED model of the main signals in the consideredrange of frequencies. We first consider likelihood analysis, which is halfway between supervised and unsupervised methods. Next, weinvestigate an unsupervised clustering technique. Finally, we consider a supervised classifier based on artificial neural networks. Weillustrate the approach and results using catalogues from various surveys, such as X-rays (MCXC), optical (SDSS), and millimetric(Planck Sunyaev-Zeldovich (SZ)). We show that the results from the statistical classifications of the three methods are in very goodagreement with each other, although the supervised neural network-based classification shows better performance allowing the bestseparation into populations of reliable and unreliable sources in catalogues. The latest method was applied to the SZ sources detectedby the Planck satellite. It led to a classification assessing and thereby agreeing with the reliability assessment published in the PlanckSZ catalogue. Our method could easily be applied to catalogues from future large surveys such as SRG/eROSITA and Euclid

Social media in cardiology: Reasons to learn how to use it

Social media has changed the way we learn, educate, and interact with our peers. The dynamic nature of social media and their immediate availability through our portable devices (smartphones, tablets, smartwatches, etc.) is quickly transforming the way we participate in society. The scope of these digital tools is broad as they deal with many different aspects: Teaching and learning, case discussion, congresses coverage, peer to peer interaction, research are examples worth mentioning. The scientific societies considered more innovative, are promoting these tools between their members. These new concepts need to be known by the cardiologists to stay updated, as countless information is moving rapidly through these channels. We summarize the main reasons why learning how to use these tools to be part of the conversation is essential for the cardiologist in training or fully stablished

Solid-state proton NMR of paramagnetic metal complexes: DANTE spin echoes for selective excitation in inhomogeneously broadened lines

The paramagnetic complex bis(oxazolinylphenyl)amine-Fe(III)Cl-2 is investigated by means of solid-state proton NMR at 18.8 T (800 MHz) using magic-angle spinning at 65 kHz. Spin echoes that are excited and refocused by combs of rotor-synchronized pulses in the manner of 'Delays Alternating with Nutation for Tailored Excitation' (DANTE) allow one to characterize different chemical environments that severely overlap in conventional MAS spectra. Such sequences combine two apparently contradictory features: an overall bandwidth exceeding several MHz, and very selective irradiation of a few kHz within inhomogeneously broadened sidebands. The experimental hyperfine interactions correlate well with DFT calculations. (C) 2013 Elsevier B.V. All rights reserved

Parents' Perceptions about Salt Consumption in Urban Areas of Peru: Formative Research for a Social Marketing Strategy.

BACKGROUND: Salt intakes in Latin America currently double the World Health Organization's recommendation of 5 g/day. Various strategies to reduce the population's salt consumption, such as raising awareness using social marketing, have been recommended. This study identified parents' perceptions of salt consumption to inform a social marketing strategy focused on urban areas in Peru. METHODS: Using a sequential exploratory methods design, parents of pre-school children, of high and low socioeconomic status, provided qualitative data in the form of interviews and focus groups. Following this, quantitative data was obtained via questionnaires, which were sent to all parents. The information was analyzed jointly. RESULTS: 296 people (mean age 35.4, 82% women) participated, 64 in the qualitative and 232 in the quantitative phase of the study. Qualitative data from the first phase revealed that the majority of mothers were in charge of cooking, and female participants expressed that cooking was "their duty" as housewives. The qualitative phase also revealed that despite the majority of the participants considered their salt intake as adequate, half of them mentioned that they have tried to reduce salt consumption, and the change in the flavor of the food was stated as the most difficult challenge to continue with such practice. Quantitative data showed that 67% of participants would be willing to reduce their salt intake, and 79.7% recognized that high salt intake causes hypertension. In total, 84% of participants reaffirmed that mothers were in charge of cooking. There were no salient differences in terms of responses provided by participants from high versus low socioeconomic groups. CONCLUSIONS: The results point towards the identification of women as a potential target-audience of a social marketing strategy to promote reductions in salt intake in their families and, therefore, a gender-responsive social marketing intervention is recommended