990 research outputs found
Climatic, edaphic, and biotic controls over storage and turnover of carbon in soils
Soil carbon, a major component of the global carbon inventory, has significant potential for change with changing climate and human land use. We applied the Century ecosystem model to a series of forest and grassland sites distributed globally to examine large-scale controls over soil carbon. Key site-specific parameters influencing soil carbon dynamics are soil texture and foliar lignin content; accordingly, we perturbed these variables at each site to establish a range of carbon concentrations and turnover times. We examined the simulated soil carbon stores, turnover times, and C:N ratios for correlations with patterns of independent variables. Results showed that soil carbon is related linearly to soil texture, increasing as clay content increases, that soil carbon stores and turnover time are related to mean annual temperature by negative exponential functions, and that heterotrophic respiration originates from recent detritus (∼50%), microbial turnover (∼30%), and soil organic matter (∼20%) with modest variations between forest and grassland ecosystems. The effect of changing temperature on soil organic carbon (SOC) estimated by Century is dSOC/dT= 183e−0.034T. Global extrapolation of this relationship leads to an estimated sensitivity of soil C storage to a temperature of −11.1 Pg° C−1, excluding extreme arid and organic soils. In Century, net primary production (NPP) and soil carbon are closely coupled through the N cycle, so that as temperatures increase, accelerated N release first results in fertilization responses, increasing C inputs. The Century-predicted effect of temperature on carbon storage is modified by as much as 100% by the N cycle feedback. Century-estimated soil C sensitivity (−11.1 Pg° C−1) is similar to losses predicted with a simple data-based calculation (−14.1 Pg° C−1). Inclusion of the N cycle is important for even first-order predictions of terrestrial carbon balance. If the NPP-SOC feedback is disrupted by land use or other disturbances, then SOC sensitivity can greatly exceed that estimated in our simulations. Century results further suggest that if climate change results in drying of organic soils (peats), soil carbon loss rates can be high
Optimization of switching losses and capacitor voltage ripple using model predictive control of a cascaded H-bridge multi-level StatCom
This paper further develops a Model Predictive Control (MPC) scheme which is able to exploit the large number of redundant switching states available in a multi-level H-bridge StatCom (H-StatCom). The new sections of the scheme provide optimised methods to trade off the harmonic performance with converter switching losses and capacitor voltage ripple. Varying the pulse placement within the modulation scheme and modifying the heuristic model of the voltage balancing characteristics allows the MPC scheme to achieve superior performance to that of the industry standard phase shifted carrier modulation technique. The effects of capacitor voltage ripple on the lifetime of the capacitors is also investigated. It is shown that the MPC scheme can reduce capacitor voltage ripple and increase capacitor lifetime. Simulation and experimental results are presented that confirm the correct operation of the control and modulation strategies
Under-reactive but easily distracted: An fMRI investigation of attentional capture in autism spectrum disorder
For individuals with autism spectrum disorder (ASD), salient behaviorally-relevant information often fails to capture attention, while subtle behaviorally-irrelevant details commonly induce a state of distraction. The present study used functional magnetic resonance imaging (fMRI) to investigate the neurocognitive networks underlying attentional capture in sixteen high-functioning children and adolescents with ASD and twenty-one typically developing (TD) individuals. Participants completed a rapid serial visual presentation paradigm designed to investigate activation of attentional networks to behaviorally-relevant targets and contingent attention capture by task-irrelevant distractors. In individuals with ASD, target stimuli failed to trigger bottom-up activation of the ventral attentional network and the cerebellum. Additionally, the ASD group showed no differences in behavior or occipital activation associated with contingent attentional capture. Rather, results suggest that to-be-ignored distractors that shared either task-relevant or irrelevant features captured attention in ASD. Results indicate that individuals with ASD may be under-reactive to behaviorally-relevant stimuli, unable to filter irrelevant information, and that both top-down and bottom-up attention networks function atypically in ASD. Lastly, deficits in target-related processing were associated with autism symptomatology, providing further support for the hypothesis that non-social attentional processes and their neurofunctional underpinnings may play a significant role in the development of sociocommunicative impairments in ASD. © 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-NDlicense
Associations between alcohol misuse and risks for HIV infection among men who have multiple female sexual partners in Cape Town, South Africa
The perceived barriers to the inclusion of rainwater harvesting systems by UK house building companies
This work investigates the barriers that exist to deter the implementation of rainwater harvesting into new UK housing. A postal questionnaire was sent to a selection of large, medium and small house-builders distributed across the UK. Questions were asked concerning potential barriers to the inclusion of rainwater harvesting in homes separated into five sections; (1) institutional and regulatory gaps, (2) economic and financial constraints, (3) absence of incentives, (4) lack of information and technical knowledge, and (5) house-builder attitudes. The study concludes that although the knowledge of rainwater systems has increased these barriers are deterring house-builders from installing rainwater harvesting systems in new homes. It is further acknowledged that the implementation of rainwater harvesting will continue to be limited whilst these barriers remain and unless resolved, rainwater harvesting's potential to reduce the consumption of potable water in houses will continue to be limited
Intentional versus unintentional nitrogen use in the United States : trends, efficiency and implications
© The Author(s), 2012. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Biogeochemistry 114 (2013): 11-23, doi:10.1007/s10533-012-9801-5.Human actions have both intentionally and unintentionally altered the global economy of nitrogen (N), with both positive and negative consequences for human health and welfare, the environment and climate change. Here we examine long-term trends in reactive N (Nr) creation and efficiencies of Nr use within the continental US. We estimate that human actions in the US have increased Nr inputs by at least ~5 times compared to pre-industrial conditions. Whereas N2 fixation as a by-product of fossil fuel combustion accounted for ~1/4 of Nr inputs from the 1970s to 2000 (or ~7 Tg N year−1), this value has dropped substantially since then (to <5 Tg N year−1), owing to Clean Air Act amendments. As of 2007, national N use efficiency (NUE) of all combined N inputs was equal to ~40 %. This value increases to 55 % when considering intentional N inputs alone, with food, industrial goods, fuel and fiber production accounting for the largest Nr sinks, respectively. We estimate that 66 % of the N lost during the production of goods and services enters the air (as NO x , NH3, N2O and N2), with the remaining 34 % lost to various waterways. These Nr losses contribute to smog formation, acid rain, eutrophication, biodiversity declines and climate change. Hence we argue that an improved national NUE would: (i) benefit the US economy on the production side; (ii) reduce social damage costs; and (iii) help avoid some major climate change risks in the future.This work resulted from a workshop
supported by NSF Research Coordination Network Awards
DEB-0443439 and DEB-1049744 and by the David and Lucille
Packard Foundation
Admission to hospital following head injury in England: Incidence and socio-economic associations
BACKGROUND:
Head injury in England is common. Evidence suggests that socio-economic factors may cause variation in incidence, and this variation may affect planning for services to meet the needs of those who have sustained a head injury.
METHODS:
Socio-economic data were obtained from the UK Office for National Statistics and merged with Hospital Episodes Statistics obtained from the Department of Health. All patients admitted for head injury with ICD-10 codes S00.0–S09.9 during 2001–2 and 2002–3 were included and collated at the level of the extant Health Authorities (HA) for 2002, and Primary Care Trust (PCT) for 2003. Incidence was determined, and cluster analysis and multiple regression analysis were used to look at patterns and associations.
Results: 112,718 patients were admitted during 2001–2 giving a hospitalised incidence rate for England of 229 per 100,000. This rate varied across the English HA's ranging from 91–419 per 100,000. The rate remained unchanged for 2002–3 with a similar magnitude of variation across PCT's. Three clusters of HA's were identified from the 2001–2 data; those typical of London, those of the Shire counties, and those of Other Urban authorities. Socio-economic factors were found to account for a high proportion of the variance in incidence for 2001–2. The same pattern emerged for 2002–3 at the PCT level. The use of public transport for travel to work is associated with a
decreased incidence and lifestyle indicators, such as the numbers of young unemployed, increase the incidence.
CONCLUSION:
Head injury incidence in England varies by a factor of 4.6 across HA's and PCT's.
Planning head injury related services at the local level thus needs to be based on local incidence
figures rather than regional or national estimates. Socio-economic factors are shown to be
associated with admission, including travel to work patterns and lifestyle indicators, which suggests
that incidence is amenable to policy initiatives at the macro level as well as preventive programmes
targeted at key groups
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Cardiac Biomarkers and Risk of Atrial Fibrillation in Chronic Kidney Disease: The CRIC Study.
Background We tested associations of cardiac biomarkers of myocardial stretch, injury, inflammation, and fibrosis with the risk of incident atrial fibrillation (AF) in a prospective study of chronic kidney disease patients. Methods and Results The study sample was 3053 participants with chronic kidney disease in the multicenter CRIC (Chronic Renal Insufficiency Cohort) study who were not identified as having AF at baseline. Cardiac biomarkers, measured at baseline, were NT-proBNP (N-terminal pro-B-type natriuretic peptide), high-sensitivity troponin T, galectin-3, growth differentiation factor-15, and soluble ST-2. Incident AF ("AF event") was defined as a hospitalization for AF. During a median follow-up of 8 years, 279 (9%) participants developed a new AF event. In adjusted models, higher baseline log-transformed NT-proBNP (N-terminal pro-B-type natriuretic peptide) was associated with incident AF (adjusted hazard ratio [HR] per SD higher concentration: 2.11; 95% CI, 1.75, 2.55), as was log-high-sensitivity troponin T (HR 1.42; 95% CI, 1.20, 1.68). These associations showed a dose-response relationship in categorical analyses. Although log-soluble ST-2 was associated with AF risk in continuous models (HR per SD higher concentration 1.35; 95% CI, 1.16, 1.58), this association was not consistent in categorical analyses. Log-galectin-3 (HR 1.05; 95% CI, 0.91, 1.22) and log-growth differentiation factor-15 (HR 1.16; 95% CI, 0.96, 1.40) were not significantly associated with incident AF. Conclusions We found strong associations between higher NT-proBNP (N-terminal pro-B-type natriuretic peptide) and high-sensitivity troponin T concentrations, and the risk of incident AF in a large cohort of participants with chronic kidney disease. Increased atrial myocardial stretch and myocardial cell injury may be implicated in the high burden of AF in patients with chronic kidney disease
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Research-based versus clinical serum creatinine measurements and the association of acute kidney injury with subsequent kidney function: findings from the Chronic Renal Insufficiency Cohort study.
Background:Observational studies relying on clinically obtained data have shown that acute kidney injury (AKI) is linked to accelerated chronic kidney disease (CKD) progression. However, prior reports lacked uniform collection of important confounders such as proteinuria and pre-AKI kidney function trajectory, and may be susceptible to ascertainment bias, as patients may be more likely to undergo kidney function testing after AKI. Methods:We studied 444 adults with CKD who participated in the prospective Chronic Renal Insufficiency Cohort (CRIC) Study and were concurrent members of a large integrated healthcare delivery system. We estimated glomerular filtration rate (eGFR) trajectories using serum creatinine measurements from (i) the CRIC research protocol (yearly) and (ii) routine clinical care. We used linear mixed effects models to evaluate the associations of AKI with acute absolute change in eGFR and post-AKI eGFR slope, and explored whether these varied by source of creatinine results. Models were adjusted for demographic characteristics, diabetes status and albuminuria. Results:During median follow-up of 8.5 years, mean rate of eGFR loss was -0.31 mL/min/1.73 m2/year overall, and 73 individuals experienced AKI (55% Stage 1). A significant interaction existed between AKI and source of serum creatinine for acute absolute change in eGFR level after discharge; in contrast, AKI was independently associated with a faster rate of eGFR decline (mean additional loss of -0.67 mL/min/1.73 m2/year), which was not impacted by source of serum creatinine. Conclusions:AKI is independently associated with subsequent steeper eGFR decline regardless of the serum creatinine source used, but the strength of association is smaller than observed in prior studies after taking into account key confounders such as pre-AKI eGFR slope and albuminuria
SDN enabled dynamically reconfigurable high capacity optical access architecture for converged services
Dynamically reconfigurable time-division multiplexing (TDM) dense wavelength division multiplexing (DWDM) long-reach passive optical networks (PONs) can support the reduction of nodes and network interfaces by enabling a fully meshed flat optical core. In this paper we demonstrate the flexibility of the TDM-DWDM PON architecture, which can enable the convergence of multiple service types on a single physical layer. Heterogeneous services and modulation formats, i.e. residential 10G PON channels, business 100G dedicated channel and wireless fronthaul, are demonstrated co-existing on the same long reach TDM-DWDM PON system, with up to 100km reach, 512 users and emulated system load of 40 channels, employing amplifier nodes with either erbium doped fiber amplifiers (EDFAs) or semiconductor optical amplifiers (SOAs). For the first time end-to-end software defined networking (SDN) management of the access and core network elements is also implemented and integrated with the PON physical layer in order to demonstrate two service use cases: a fast protection mechanism with end-to-end service restoration in the case of a primary link failure; and dynamic wavelength allocation (DWA) in response to an increased traffic demand
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