Exercise for men with prostate cancer : a systematic review and meta-analysis

Context: Exercise could be beneficial for prostate cancer survivors. However, no systematic review across cancer stages and treatment types addressing potential benefits and harms exists to date. Objective: To assess the effects of exercise on cancer-specific quality of life and adverse events in prostate cancer trials. Evidence acquisition: We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, AMED, CINAHL, PsycINFO, SPORTDiscus, and PEDro. We also searched grey literature databases, including trial registers. Searches were from database inception to March 2015. Standardised mean differences (SMDs) were calculated for meta-analysis. Evidence synthesis: We included 16 randomised controlled trials (RCTs) involving 1574 men with prostate cancer. Follow-up varied from 8 wk to 12 mo. RCTs involved men with stage I–IV cancers. A high risk of bias was frequently due to problematic intervention adherence. Seven trials involving 912 men measured cancer-specific quality of life. Pooling of the data from these seven trials revealed no significant effect on this outcome (SMD 0.13, 95% confidence interval [CI] –0.08 to 0.34, median follow-up 12 wk). Sensitivity analysis of studies that were judged to be of high quality indicated a moderate positive effect estimate (SMD 0.33, 95% CI 0.08–0.58; median follow-up 12 wk). Similar beneficial effects were seen for cancer-specific fatigue, submaximal fitness, and lower body strength. We found no evidence of benefit for disease progression, cardiovascular health, or sexual function. There were no deaths attributable to exercise interventions. Other serious adverse events (eg, myocardial infarction) were equivalent to those seen in controls. Conclusions: These results support the hypothesis that exercise interventions improve cancer-specific quality of life, cancer-specific fatigue, submaximal fitness, and lower body strength. Patient summary: This review shows that exercise/physical activity interventions can improve quality of life, fatigue, fitness, and function for men with prostate cancer

The football is medicine plaform-scientific evidence, large-scale implementation of evidence-based concepts and future perspectives

The idea that football can be used as therapy and as a high-intensity and literally breath-taking training regime goes back centuries. To take one prominent example, the French philosopher Voltaire describes in the Book of Fate (1747), how a patient is cured by playing with a sacred football: “… full-blown and carefully covered with the softest Leather. You must kick this Bladder, Sir, once a Day about your Hall for a whole Hour together, with all the Vigour and Activity you possibly can”, “Ogul, upon making the first Experiment, was ready to expire for want of Breath”, “In short, our Doctor in about 8 days Time, performed an absolute Cure. His Patient was as brisk, active and gay, as One in the Bloom of his Youth.”1 Today, Voltaire and his main character, philosopher Zadig, have been proved right: Football is indeed a breath-taking activity and it can be used as therapy. Albeit today's recommendations suggest a lower training frequency, longer training periods and encourage group-based training, and say that any football can be applied

Experimental and numerical analysis of dynamic compressive response of Nomex honeycombs

Lightweight phenolic resin-impregnated aramid paper honeycombs, commercially known as Nomex®honeycombs, are promising cores for sandwich structures in aerospace applications due to their high ratios of stiffness and strength to density. The out-of-plane compressive properties of the Nomex honeycombs have been widely investigated under quasi-static and low strain rates (up to 300 s-1). There is a need to understand the behaviour of this structure under higher strain rate compression. This will widen the applicability of these structures to more areas such as debris impact and other impacts which induce high strain rates. This paper reports the out-of-plane compressive responses of Nomex honeycombs subject to quasi-static loading and high strain rate dynamic loading up to 1500 s-1. The work involves experimental measurements and numerical modelling and validation. The compressive responses of the honeycombs were measured using a sensitive magnesium alloy Kolsky bar setup with front and back face impacts. The failure modes of the Nomex honeycombs were identified to be different under quasi-static and dynamic compressions. Under quasi-static compression, the honeycombs failed with local phenolic resin fracture after the elastic buckling of the honeycomb walls. For the dynamic compression, the honeycombs failed with the stubbing of cell walls at the ends of specimens. A finite element (FE) numerical model was devised and validated with the experimental data. The FE model considered the strain rate effect of phenolic resin material. The model predictions were in good agreement with the experimental measurements and facilitated interpreting the out-of-plane compressive response of the Nomex honeycombs. It was shown that there was a linear compressive strength enhancement up to 30% from quasi-static to strain rate of 1500 s-1. The strength enhancement was governed by two mechanisms: the strain rate effect of the phenolic resin and inertial stabilization of the honeycomb unit cell walls, where 61%-74% of the enhancement was contributed by the inertial stabilization of the unit cell walls. In addition, it was shown that the impact method and initial imperfections had negligible effect on the compressive response of the Nomex honeycombs

Scheitholzvergaserkessel - eine moderne und umweltfreundliche Alternative fuer die Energieerzeugung im haeuslichen Bereich

The decision to install a billet wood gasification boiler is a conscious vote using renewable fuels in the residential sector. This brochure has been elaborated to facilitate interrested citizens the right selection of this boilers. So an effective evaluation of the listed boiler types is possible. Text and tables are based on a manufacturers questionnaire, taking place from 1995 to September 1999respectively in October 2000 due to a fast technological development were actualized. Furthermore new sellers appeared upgrading their product spectra in the heating sector by advanced wood gasification boilers.(GL)Die Entscheidung zur Installation eines Scheitholzvergaserkessels ist ein bewusstes Votum zum Einsatz eines nachwachsenden Brennstoffes im haeuslichen Bereich. Um ineressierten Buergern die Auswahl geeigneter Kessel zu erleichtern, wurde die vorliegende Broschuere ausgearbeitet. Damit ist eine effektive Beurteilung der aufgelisteten Kesseltypen moeglich. Text und Tabellen basieren auf einer Herstellerumfrage aus dem Jahr 1995, die im September 1999 bzw. im Oktober 2000 auf grund der rasanten technischen Entwicklung dieses Sektors aktualisiert werden musste. Darueber hinaus sind gaenzlich neue Anbieter aufgetreten, die ihre Produktpalette im Heizungsbereich mit modernen Scheitholzvergaserkesseln aufwerten wollen (Pflege des ''Oekoimage'').(orig/GL)SIGLEAvailable from TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Ernaehrung, Landwirtschaft und Forsten, Berlin (Germany)2. rev. ed.DEGerman