Effect of Death Jumps and Back Squats on Eliciting Postactivation Potentiation for a 40-meter Sprint

Please refer to the pdf version of the abstract located adjacent to the title

Kentucky Bluegrass Floral Induction and Cultivar Response to Mechanical Removal of Harvest Residue

Open-field burning of post-harvest residue from Kentucky bluegrass (Poa pratensis L.) seed fields is being phased out in Washington, USA and may be banned in Idaho. Burning encourages early fall regrowth and timely completion of fall floral induction. Cultivars have different floral induction requirements and respond differently to mechanical residue removal. Our objective was to determine if length of fall floral induction requirement was related to seed yield when post-harvest residue was removed by crewcut vacuum sweeping. Floral induction requirements were not related to first-or second-year seed yields. Third-year seed yield of cultivars with long floral induction requirements declined more than third-year seed yields of cultivars with short floral induction requirements. Turf type, aggressive cultivars usually have longer floral induction requirements than non-aggressive cultivars. Exceptions suggest that turf type cultivars with short floral induction requirements can be developed. Cultivar selection will be important for sustained yields with mechanical residue removal

Post Activation Potentiation of Back Squat and Trap Bar Deadlift on Acute Sprint Performance

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NONLINEAR ESTIMATION OF GROWTH CURVE MODELS FOR GERMINATION DATA ANALYSIS

Logistic, Gompertz, Richards and Weibull growth curves were evaluated for their suitability as mathematical and empirical models to represent cumulative germination. By avoiding the limitations associated with the method of moments and single-value germination indices, the fitted models provided superior description of the time course of germination. The four-parameter Weibull model gave the best fit across a relatively wide range of seed species and germination conditions, and the resulting parameter estimates reflected identifiable aspects of the germination process. The nonlinear estimation of the germination response included a parameter summary, together with their asymptotic standard errors and correlation matrix, along with an approximate band for the expectation function, pairwise plots of the parameter inference region, and profile t plots. Evaluation of the fitted models also included information on lack of fit and residual structure. Empirical results and hypothesis testing were demonstrated with reference to a replicated experiment designed to determine the effects of reduced water potential on germination of onion seeds

Whole Genome Sequencing Analysis of an Idiopathic Intellectual Disability Syndrome

We present a new idiopathic intellectual disability syndrome accompanied with distinctive facial dysmorphology. X-chromosome inactivation assays reveal skewing in the mother, suggesting the possibility of an X-linked disorder. High-density genotyping arrays were performed on both children revealing no known causal or pathogenic SNVs and no known CNVs that might contribute to the phenotype. Whole genome sequencing was performed with Complete Genomics and subsequent sequence analysis led to the identification of severa

Effects of a Three-week Core Training Program on Different Unstable Platforms

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The longer your work hours, the worse your relationship? The role of selective optimization with compensation in the associations of working time with relationship satisfaction and self-disclosure in dual-career couples

This two-wave panel study investigates the associations between working time, selective optimization with compensation in private life and relationship outcomes (i.e. relationship satisfaction and self-disclosure) in dual-career couples. We propose that one partner’s selective optimization with compensation in private life either mediates or moderates the association of this partner’s working time and relationship outcomes (i.e. relationship satisfaction and self-disclosure). Moreover, we postulate the crossover (i.e. transmission) of relationship satisfaction and self-disclosure within the couple. To test these hypotheses, we conducted an online study with a time lag of six months, in which 285 dual-career couples took part. We found evidence for selective optimization with compensation in private life as a mediator: working time spent by partners in dual-career couples was associated with selective optimization with compensation in their private life that, in turn, predicted relationship satisfaction and self-disclosure. Results did not support the assumption that one partner’s selective optimization with compensation in private life moderates the association between working time and relationship satisfaction and self-disclosure. Relationship satisfaction, but not self-disclosure, crossed over within the couples. The results challenge the assumption that longer work hours have negative consequences for romantic relationships

Continuous, Real-Time Monitoring of Cocaine in Undiluted Blood Serum via a Microfluidic, Electrochemical Aptamer-Based Sensor

The development of a biosensor system capable of continuous, real-time measurement of small-molecule analytes directly in complex, unprocessed aqueous samples has been a significant challenge, and successful implementation has been achieved for only a limited number of targets. Towards a general solution to this problem, we report here the Microfluidic Electrochemical Aptamer-based Sensor (MECAS) chip wherein we integrate target-specific DNA aptamers that fold, and thus generate an electrochemical signal, in response to the analyte with a microfluidic detection system. As a model, we demonstrate the continuous, real-time (~1 minute time resolution) detection of the small molecule drug cocaine at near physiological, low micromolar concentrations directly in undiluted, otherwise unmodified blood serum. We believe our approach of integrating folding-based electrochemical sensors with miniaturized detection systems may lay the ground work for the realtime, point-of-care detection of a wide variety of molecular targets

Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1.

The histiocytoses are rare tumors characterized by the primary accumulation and tissue infiltration of histiocytes and dendritic cells. Identification of the activating BRAFV600E mutation in Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis (LCH) cases provided the basis for the treatment with BRAF and/or MEK inhibitors, but additional treatment options are needed. Twenty-four cases of neoplastic histiocytic diseases [11 extrapulmonary LCH, 4 ECD, 4 extranodal Rosai-Dorfman disease (RDD), 3 follicular dendritic cell sarcoma (FDCS), 1 histiocytic sarcoma (HS) and 1 blastic plasmacytoid dendritic cell neoplasm (BPDCN)] were analyzed using immunohistochemical and mutational analysis in search of biomarkers for targeted therapy. BRAF V600E mutations were detected in 4/11 LCH and 4/4 ECD cases. A pathogenic PTEN gene mutation and loss of PTEN protein expression were identified in the case of HS. Increased expression of PD-L1 (≥2+/≥5%) was seen in 3/4 ECD, 7/8 LCH, 3/3 FDCS and 1/1 HS, with overall 81% concordance between 2 antibodies used in the study (SP142 vs. MAB1561 clone). These results show for the first time significant expression of the PD-L1 immune checkpoint protein in these disorders, which may provide rationale for addition of immune check-point inhibitors in treatment of disseminated and/or refractory histiocytoses

Continuous, Real-Time Monitoring of Cocaine in Undiluted Blood Serum via a Microfluidic, Electrochemical Aptamer-Based Sensor

The development of a biosensor system capable of continuous, real-time measurement of small-molecule analytes directly in complex, unprocessed aqueous samples has been a significant challenge, and successful implementation has been achieved for only a limited number of targets. Towards a general solution to this problem, we report here the Microfluidic Electrochemical Aptamer-based Sensor (MECAS) chip wherein we integrate target-specific DNA aptamers that fold, and thus generate an electrochemical signal, in response to the analyte with a microfluidic detection system. As a model, we demonstrate the continuous, real-time (~1 minute time resolution) detection of the small molecule drug cocaine at near physiological, low micromolar concentrations directly in undiluted, otherwise unmodified blood serum. We believe our approach of integrating folding-based electrochemical sensors with miniaturized detection systems may lay the ground work for the realtime, point-of-care detection of a wide variety of molecular targets