A Rare Case of Hip Pain Secondary to Pigmented Villonodular Synovitis

A 19-year-old Asian male presented to our emergency department with atraumatic right hip pain radiating to the right groin associated with pain on ambulation. Magnetic resonance imaging of the right hip with and without contrast revealed the diagnosis. Pigmented villonodular synovitis is a rare, monoarticular benign tumor originating from the synovium of the joint. The treatment is synovectomy of the pathological joint to prevent further disease progression

Intrinsic Optical and Electronic Properties from Quantitative Analysis of Plasmonic Semiconductor Nanocrystal Ensemble Optical Extinction

The optical extinction spectra arising from localized surface plasmon resonance in doped semiconductor nanocrystals (NCs) have intensities and lineshapes determined by free charge carrier concentrations and the various mechanisms for damping the oscillation of those free carriers. However, these intrinsic properties are convoluted by heterogeneous broadening when measuring spectra of ensembles. We reveal that the traditional Drude approximation is not equipped to fit spectra from a heterogeneous ensemble of doped semiconductor NCs and produces fit results that violate Mie scattering theory. The heterogeneous ensemble Drude approximation (HEDA) model rectifies this issue by accounting for ensemble heterogeneity and near-surface depletion. The HEDA model is applied to tin-doped indium oxide NCs for a range of sizes and doping levels but we expect it can be employed for any isotropic plasmonic particles in the quasistatic regime. It captures individual NC optical properties and their contributions to the ensemble spectra thereby enabling the analysis of intrinsic NC properties from an ensemble measurement. Quality factors for the average NC in each ensemble are quantified and found to be notably higher than those of the ensemble. Carrier mobility and conductivity derived from HEDA fits matches that measured in the bulk thin film literature

Tuning Nanocrystal Surface Depletion by Controlling Dopant Distribution as a Route Toward Enhanced Film Conductivity

Electron conduction through bare metal oxide nanocrystal (NC) films is hindered by surface depletion regions resulting from the presence of surface states. We control the radial dopant distribution in tin-doped indium oxide (ITO) NCs as a means to manipulate the NC depletion width. We find in films of ITO NCs of equal overall dopant concentration that those with dopant-enriched surfaces show decreased depletion width and increased conductivity. Variable temperature conductivity data shows electron localization length increases and associated depletion width decreases monotonically with increased density of dopants near the NC surface. We calculate band profiles for NCs of differing radial dopant distributions and, in agreement with variable temperature conductivity fits, find NCs with dopant-enriched surfaces have narrower depletion widths and longer localization lengths than those with dopant-enriched cores. Following amelioration of NC surface depletion by atomic layer deposition of alumina, all films of equal overall dopant concentration have similar conductivity. Variable temperature conductivity measurements on alumina-capped films indicate all films behave as granular metals. Herein, we conclude that dopant-enriched surfaces decrease the near-surface depletion region, which directly increases the electron localization length and conductivity of NC films

Monolithic in-based III-V compound semiconductor focal plane array cell with single stage CCD output

A monolithic semiconductor imager includes an indium-based III-V compound semiconductor monolithic active layer of a first conductivity type, an array of plural focal plane cells on the active layer, each of the focal plane cells including a photogate over a top surface of the active layer, a readout circuit dedicated to the focal plane cell including plural transistors formed monolithically with the monolithic active layer and a single-stage charge coupled device formed monolithically with the active layer between the photogate and the readout circuit for transferring photo-generated charge accumulated beneath the photogate during an integration period to the readout circuit. The photogate includes thin epitaxial semiconductor layer of a second conductivity type overlying the active layer and an aperture electrode overlying a peripheral portion of the thin epitaxial semiconductor layer, the aperture electrode being connectable to a photogate bias voltage

It’s not about the pain – it’s about the feedback’: krav maga experts’ views on self-defence performance and the experience of contact, pain and injury in the process of skill development

Expert performance in self-defence situations has not been the subject of rigorous empirical investigation. This study aims is broaden knowledge in self-defence, its development and the role of contact, pain and inju- ry in training, in order to stimulate future research activity. Semi-structured interviews with two Israeli krav maga experts centred on the development of expertise in self-defence. The interviews were analysed using an interpretative phenomenological framework; an induc- tive approach that captures the richness and complexity of the lived experience. Two analytically leading themes emerged concerning a) the characteristics of expert self-defence performance and b) the benefits, drawbacks and limitations of contact and pain in training activities. By examining the analytic observation through a theoretical lens with regards to (a) the key components of decision-making and mind-set and (b) contact, pain and injury in the training process, we point the direction for further avenues of inquiry in the context of self-defence performance and the development of the associated skills

Topics, Sources and Applicability of Coaching Knowledge in Police Training

The current study explored police trainers’ perceptions of their actual and preferred methods of acquiring new coaching knowledge; the types of knowledge they currently require and/or desire; and how they apply new knowledge. A total of 163 police trainers from Germany and Austria participated in the study. The responses were analysed using an inductive approach. The results showed that police trainers thought they needed knowledge of pedagogy, policing, and self-development, with reasons being centred around a need to optimise learning, training content and the engagement of learners within the training sessions. Preferred methods of learning focused predominantly around informal and non-formal opportunities, the reasons for which were social interaction, the reality-based focus of the content and the perceived quality. Finally, police trainers identified technical or tactical policing knowledge, or knowledge specific to the delivery of police training as useful, recently acquired coaching knowledge, mainly because it was perceived to have direct application to their working practices. Based on these findings, it is suggested police trainers are in need of context-specific knowledge and support to develop the declarative knowledge structures that afford critical reflection of new information

Mammalian ANP32A and ANP32B proteins drive differential polymerase adaptations in avian influenza virus

ANP32 proteins, which act as influenza polymerase cofactors, vary between birds and mammals. In mammals, ANP32A and ANP32B have been reported to serve essential but redundant roles to support influenza polymerase activity. The well-known mammalian adaptation PB2-E627K enables influenza polymerase to use mammalian ANP32 proteins. However, some mammalian-adapted influenza viruses do not harbor this substitution. Here, we show that alternative PB2 adaptations, Q591R and D701N, also allow influenza polymerase to use mammalian ANP32 proteins, whereas other PB2 mutations, G158E, T271A, and D740N, increase polymerase activity in the presence of avian ANP32 proteins as well. Furthermore, PB2-E627K strongly favors use of mammalian ANP32B proteins, whereas D701N shows no such bias. Accordingly, PB2-E627K adaptation emerges in species with strong pro-viral ANP32B proteins, such as humans and mice, while D701N is more commonly seen in isolates from swine, dogs, and horses, where ANP32A proteins are the preferred cofactor. Using an experimental evolution approach, we show that the passage of viruses containing avian polymerases in human cells drove acquisition of PB2-E627K, but not in the absence of ANP32B. Finally, we show that the strong pro-viral support of ANP32B for PB2-E627K maps to the low-complexity acidic region (LCAR) tail of ANP32B. IMPORTANCE Influenza viruses naturally reside in wild aquatic birds. However, the high mutation rate of influenza viruses allows them to rapidly and frequently adapt to new hosts, including mammals. Viruses that succeed in these zoonotic jumps pose a pandemic threat whereby the virus adapts sufficiently to efficiently transmit human-to-human. The influenza virus polymerase is central to viral replication and restriction of polymerase activity is a major barrier to species jumps. ANP32 proteins are essential for influenza polymerase activity. In this study, we describe how avian influenza viruses can adapt in several different ways to use mammalian ANP32 proteins. We further show that differences between mammalian ANP32 proteins can select different adaptive changes and are responsible for some of the typical mutations that arise in mammalian-adapted influenza polymerases. These different adaptive mutations may determine the relative zoonotic potential of influenza viruses and thus help assess their pandemic risk

Main crustal seismic sources in El Salvador

We present a map and a data set containing information about intra-plate seismic sources in El Salvador. These are the results of the field campaigns and data analysis carried out by the research group of Planetary Geodinamics, Active Tectonics and Related Risks from Complutense University of Madrid during the last 12 years. We include two maps, the first map contains 1405 fault traces with evidences of Quaternary activity derived form morphometric, paleoseismological and geomorphological analysis together with field data mapping carried in El Salvador. The second map is a synthesis of the 29 intra-plate seismic sources selected from the quaternary faults map. The geometry of these sources was simplified and we also include a table where some available data of the proposed sources are included, such as their name, orientation, length and slip-rate. For further interpretation and discussion of these sources see (Alonso-Henar et al., 2018) [1, doi.org/10.1016/j.enggeo.2018.06.015]This research was supported by the project“ QUAKESTEP”(CGL2017–83931-C3-1-P) founded by the Spanish Ministry of Science, Innovation and Universities. We are grateful to our colleagues atDGOA-MARN (Observatorio Ambiental del Ministerio de Medio Ambiente y Recursos Naturales de ElSalvador): Manuel Díaz, Walter Hernandez and Douglas Hernández for their assistance. Figures were produced using GMT softwar