450 research outputs found

    Man, Meaning and History

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    Indonesi

    Self-regulation in boys with oppositional defiant disorder and conduct disorder

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    Kinderen met een oppositioneel opstandige gedragsstoornis (ODD) of antisociale gedragsstoornis (CD) hebben een verhoogd risico op toekomstig probleemgedrag zoals delinquentie, werkeloosheid en psychiatrische problemen. Om beter te begrijpen waarom kinderen agressief en antisociaal gedrag vertonen en dit gedrag positief te kunnen beïnvloeden is het nuttig om naar de onderliggende cognitieve en neurobiologische processen te kijken, welke onderliggend zijn aan (probleem)gedrag. Eén van die mechanismen is zelfregulatie: het vermogen om controle uit te kunnen oefenen over onze gedachten, emoties en gedrag. In dit onderzoek hebben we zelfregulatie onderzocht door vier aspecten van zelfregulatie te onderzoeken: neurobiologie (ANS, HPA-as), emotieregulatie; executieve functies en gedrag. We onderzochten 65 jongens met ODD/CD en 38 normaal ontwikkelende controle jongens in de leeftijd van 8-12 jaar in rust en in een stressvolle situatie. We ontdekten dat jongens met ODD/CD een heterogene groep vormen zowel op gedragsniveau als neurobiologisch niveau. Daarnaast zagen we dat er specifieke relaties zijn tussen neurobiologische factoren en verschillende gedragsproblemen en dat de neurobiologie voorspellend is voor het verloop van agressie over een jaar tijd. Deze informatie is belangrijk omdat het laat zien dat interventies moeten aansluiten op het individu, passend bij het mechanisme dat onderliggend is aan het probleemgedrag en verstoord is.  NWO; project nummer: 056-21-010Development Psychopathology in context: clinical setting

    Erythrocyte deformability and aggregability in patients undergoing colon cancer surgery and effects of two infusions with omega-3 fatty acids

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    BACKGROUND: An adequate erythrocyte function is vital for tissue oxygenation and wound healing. The erythrocyte membrane phospholipid composition plays an important role in erythrocyte function and administration of omega-3 fatty acids may provide a means to improve it. OBJECTIVE: To investigate peri-operative erythrocyte function and effects of omega-3 fatty acids METHODS: Forty-four patients undergoing elective laparoscopic colon resection for non-metastasized cancer were randomized between intravenous omega-3 poly-unsaturated fatty acids (n-3 PUFAs) or placebo (saline). Peri-operative blood samples were analyzed with a Lorrca MaxSIS Ektacytometer and erythrocyte membrane phospholipids were determined with gas chromatography. RESULTS: Patient and operation characteristics were equal between groups. There was a significant increase in erythrocyte membrane eicosapentaenoic acid (EPA) but not docosahexaenoic acid (DHA) in the n-PUFA group. There were no significant differences in erythrocyte deformability but the aggregation index (AI) was significantly lower and the aggregation half time (T 1/2) was significantly higher in the n-3 PUFA group. CONCLUSION: This study confirms rapid changes in erythrocyte membrane phospholipid composition after administration of intravenous n-3 PUFAs. Erythrocyte deformability parameters were not affected but erythrocyte aggregability was decreased in the n-3 PUFA group. Further investigation is necessary to gain more insights in the effects of n-3 PUFA and the postoperative inflammatory response on erythrocyte function

    Algunos ejemplos de relación entre agregación, capacidad de infiltración y erosión en suelos mediterráneos

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    [Resumen] Este trabajo tiene por objeto evaluar la influencia de la agregación sobre la capacidad de infiltración y la tendencia a la erosión de suelos mediterráneos sobre litología caliza. Se identifican algunas variables de agregación que influyen de una manera importante en la infiltración y la erosión, aunque es en combinación con otras características del suelo cuando estas variables explican mejor dichos parámetros. Se consiguen una serie de modelos de ecuaciones de regresión múltiple basadas en variables indicadoras de la agregación de los suelos y otras características (cobertura vegetal, materia orgánica, pedregosidad y humedad del suelo) que explican bastante bien la capacidad de infiltración, la concentración de sedimentos y la erosión de los suelos en las zonas de estudio.[Abstract] The objective of this work is to evaluate the influence of soil aggregation on soil infiltration capacity and erosion in mediterranean soils developed on limestones. Sorne key-variables related to soil aggregation which play an important role on soil infiltration capacity and erosion are identified. Especially the combination of these variables with other soil characterisitics give the most satisfactory results explaining soil infiltration and erosiono Sorne models of multiple regression equations based in variables related to aggregation and other soil characteristics (vegetation cover, organic matter, stoniness and soil moisture) are obtained. They explain quite well the infiltration capacity, the sediment concentration and the erosion in the study zones

    Influencia de la estructura y usos del suelo en las características de retención hídrica de suelos mediterráneos sobre litología caliza

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    [Resumen] Se investigan las diferencias entre la capacidad de retención hídrica de suelos mediterráneos sobre litología caliza sometidos a diferentes usos: incendiados y bajo pastoreo intensivo. En estos mismos suelos se valoran las relaciones entre estructura del suelo y capacidad de retención hídrica a diversos puntos de la curva de retención. Agregados de pequeño tamaño y materia orgánica influyen positivamente y de manera considerable en la capacidad de retención en casi todos los puntos de la curva de retención determinados. Agregados de gran tamaño y microagregados estables en agua influyen negativamente. La combinación de agregados de tamaño 1-0,105 mm y el contenido en materia orgánica predicen bastante bien la capacidad de retención a niveles bajos de succión (pF 0,4 YpF 1).[Abstract] The differences between the water holding capacity of Mediterranean soils developed on limestones and under different land uses (burnt and overgrazed soils) are investigated. The relationships between soil structure and soil moisture characteristic at different levels of the water retention curve in these same soils are evaluated. Organic matter and small sized aggregates are positively related to the water holding capacity. Large sized aggregates and waterstable microaggregates are negatively related to the water holding capacity of the soils. The combination of aggregates at 1-0,105 mm and organic matter content predict quite well the water retention capacity at lower suction levels (pF 0,4 and pF 1)

    Епідигматичний модус англійських числівників

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    У статті розглядаються англійські числівники, денумеративи та їх епідигматичний модус. Семантична структура порівнюваних груп розглядаються на векторах їх походження та модифікації. Частиномовна представленість досліджується на просторах їх граматичного, семантичного і словотворчого буття. Визначаються перспективи подальшого дослідження. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/30551В статье исследуются английские числительные, денумеративы, а также их эпидигматичекие аспекты. Семантическая структура сравниваемых единиц изучается на векторах семантики, грамматики и словотворчества. Намечаются перспективы дальнейшего исследования. При цитировании документа, используйте ссылку http://essuir.sumdu.edu.ua/handle/123456789/30551The article in question deals with the English numerals, denumerals and their epidigmatic tendencies. The semantic structures of both groups are being focused upon. The words under analysis are viewed in terms of their initial and secondary grounds. The item of part of speech charge is being considered in terms of grammatical, semantic and epidigmatic aspects. Thus, the modus of the paradigmatic groups have been considered wide perspectives for further investigation. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3055

    Electron microscopic observation in case of platelet activation in a chronic haemodialysis subject

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    During haemodialysis (HD), platelets (PLTs) are activated and release granule contents. As HD treatment occurs three times a week, it has been demonstrated that PLTs are exhausted due to the repetitive character of the treatment. To identify PLT depletion morphologically, PLT evaluation was performed by light microscopy and electron microscopy (EM) in a chronic HD subject and a healthy reference subject. Blood samples were taken before the start of HD treatment for measurement of PLT count, PLT volume and size parameters. Blood smears were screened by light microscopy for qualitative evaluation of PLT granule containing cytoplasm, as indicated by its staining density. Morphological PLT parameters of surface area and size of dense bodies were assessed by EM. Data were compared with results of a group of 20 chronic HD subjects and a group of 20 healthy reference subjects. With respect to the percentage of PLTs with appropriate staining density (>75%), light microscopic evaluation showed that this value (9%) was within the range of a group of chronic HD subjects, but considerably below the reference range (70%). EM evaluation revealed an average PLT surface area and dense bodies area of respectively 42% and 31%, if the healthy reference subject was set on 100%. PLTs from a chronic HD subject are considerably smaller and substantially less granular than PLTs from a healthy reference subject. These findings support the hypothesis of PLT depletion in chronic HD subjects due to frequent PLT activation and/or increased urea concentrations
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