291 research outputs found
Conceptual mechanization studies for a horizon definition spacecraft attitude control subsystem, phase A, part II, 10 October 1966 - 29 May 1967
Attitude control subsystem for spin stabilized spacecraft for mapping earths infrared horizon radiance profiles in 15 micron carbon dioxide absorption ban
Computer recommendations for an automatic approach and landing system for V/STOL aircraft. Volume 1 - Computer recommendations
Evaluation of digital computer for V/STOL aircraft automatic approach and landing syste
A comparison of meningococcal carriage by pregnancy status
Neisseria meningitidis is the second leading cause of invasive meningitis. A prerequisite for infection is colonization of the nasopharynx, and asymptomatic carrier rates are widely reported in the range of 10-15%. Recent reports have indicated an increased likelihood that a pediatric admission for Neisseria meningitidis will have a mother who is pregnant in the home. We hypothesized that this association may relate to immunologic changes in pregnancy leading to higher carrier rates
Miscibility amongst AVSb kagome superconductors: design of mixed A-site AVSb (A: K, Rb, Cs) alloys
In this work we explore the chemical-property phase diagram of the
AVSb family through A-site alloying. We demonstrate full miscibility of
the alkali-site, highlighting that the three parent compounds are the terminal
ends of a single solid-solution. Using both polycrystalline and single crystal
methods, we map the dependence of the two primary electronic instabilities: (1)
the onset of charge density wave (CDW) order () and (2) the onset
of superconductivity () with alkali-site composition. We show
continuous trends in both and , including a region
of enhanced CDW stability in KCsVSb alloys. Together, our
results open new routes for chemical perturbation and exploration of the
chemical-property relationships in the class of AVSb kagome
superconductors
Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 2: Routes to Bicyclic Sultams
The synthesis of a library of bicyclic sultams incorporating the 1,5,2-dithiazepine 1,1-dioxide moiety is reported. Following scaffold synthesis via a one-pot sulfonylation/intramolecular thia-Michael protocol, several additional cyclization strategies have been realized enabling access to new bicyclic sultams
Access to primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in Canada: a geographic analysis
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Exploiting the retinal vascular geometry in identifying the progression to diabetic retinopathy using penalized logistic regression and random forests
Many studies have been conducted, investigating the effects that diabetes has to the retinal vasculature. Identifying and quantifying the retinal vascular changes remains a very challenging task, due to the heterogeneity of the retina. Monitoring the progression requires follow-up studies of progressed patients, since human retina naturally adapts to many different stimuli, making it hard to associate any changes with a disease. In this novel study, data from twenty five diabetic patients, who progressed to diabetic retinopathy, were used. The progression was evaluated using multiple geometric features, like vessels widths and angles, tortuosity, central retinal artery and vein equivalent, fractal dimension, lacunarity, in addition to the corresponding descriptive statistics of them. A statistical mixed model design was used to evaluate the significance of the changes between two periods: 3 years before the onset of diabetic
retinopathy and the first year of diabetic retinopathy. Moreover, the discriminative power of these features was evaluated using a random forests classifier and also a penalized logistic regression. The area under the ROC curve after running a ten-fold cross validation was 0.7925 and 0.785 respectively
Absence of bias against smokers in access to coronary revascularization after cardiac catheterization
OBJECTIVE: Many consider smoking to be a personal choice for which individuals should be held accountable. We assessed whether there is any evidence of bias against smokers in cardiac care decision-making by determining whether smokers were as likely as non-smokers to undergo revascularization procedures after cardiac catheterization. DESIGN: Prospective cohort study. Subjects and setting. All patients undergoing cardiac catheterization in Alberta, Canada. MAIN MEASURE: Patients were categorized as current smokers, former smokers, or never smokers, and then compared for their risk-adjusted likelihood of undergoing revascularization procedures (percutaneous coronary intervention or coronary artery bypass grafting) after cardiac catheterization. RESULTS: Among 20406 patients undergoing catheterization, 25.4% were current smokers at the time of catheterization, 36.6% were former smokers, and 38.0% had never smoked. When compared with never smokers (reference group), the hazard ratio for undergoing any revascularization procedure after catheterization was 0.98 (95% CI 0.93-1.03) for current smokers and 0.98 (0.94-1.03) for former smokers. The hazard ratio for undergoing coronary artery bypass grafting was 1.09 (1.00-1.19) for current smokers and 1.00 (0.93-1.08) for former smokers. For percutaneous coronary intervention, the hazard ratios were 0.93 (0.87-0.99) for current smokers and 1.00 (0.94-1.06) for former smokers. CONCLUSION: Despite potential for discrimination on the basis of smoking status, current and former smokers undergoing cardiac catheterization in Alberta, Canada were as likely to undergo revascularization procedures as catheterization patients who had never smoked
Retinal microvascular network geometry and cognitive abilities in community-dwelling older people:The Lothian Birth Cohort 1936 study
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