Rotor and control system loads analysis of the XV-15 with the advanced technology blades

An analysis of the rotor and control system loads of the XV-15 with the Advanced Technology Blades (XV-15/ATB) was conducted to study the effects of modifications designed to alleviate high collective actuator loads encountered during initial flight tests. Rotor loads predictions were correlated with flight data to establish accuracies of the methodology used in the analysis. Control system loads predictions were then examined and were also correlated with flight data. The results showed a significant reduction in 3/rev collective actuator loads of the XV-15/ATB when the control system stiffness was increased and the rotor blade chord balance and tip twist were modified

The search for novel analgesics: re-examining spinal cord circuits with new tools

In this perspective, we propose the absence of detailed information regarding spinal cord circuits that process sensory information remains a major barrier to advancing analgesia. We highlight recent advances showing that functionally discrete populations of neurons in the spinal cord dorsal horn play distinct roles in processing sensory information. We then discuss new molecular, electrophysiological, and optogenetic techniques that can be employed to understand how dorsal horn circuits process tactile and nociceptive information. We believe this information can drive the development of entirely new classes of pharmacotherapies that target key elements in spinal circuits to selectively modify sensory function and blunt pain

Approximate roots of a valuation and the Pierce-Birkhoff Conjecture

This paper is a step in our program for proving the Piece-Birkhoff Conjecture for regular rings of any dimension (this would contain, in particular, the classical Pierce-Birkhoff conjecture which deals with polynomial rings over a real closed field). We first recall the Connectedness and the Definable Connectedness conjectures, both of which imply the Pierce - Birkhoff conjecture. Then we introduce the notion of a system of approximate roots of a valuation v on a ring A (that is, a collection Q of elements of A such that every v-ideal is generated by products of elements of Q). We use approximate roots to give explicit formulae for sets in the real spectrum of A which we strongly believe to satisfy the conclusion of the Definable Connectedness conjecture. We prove this claim in the special case of dimension 2. This proves the Pierce-Birkhoff conjecture for arbitrary regular 2-dimensional rings

Individualisation of time-motion analysis : a method comparison and case report series

© Georg Thieme Verlag KG. This study compared the intensity distribution of time-motion analysis data, when speed zones were categorized by different methods. 12 U18 players undertook a routine battery of laboratory- and field-based assessments to determine their running speed corresponding to the respiratory compensation threshold (RCT), maximal aerobic speed (MAS), maximal oxygen consumption (vVO 2max ) and maximal sprint speed (MSS). Players match-demands were tracked using 5 Hz GPS units in 22 fixtures (50 eligible match observations). The percentage of total distance covered running at high-speed (%HSR), very-high speed (%VHSR) and sprinting were determined using the following speed thresholds: 1) arbitrary; 2) individualised (IND) using RCT, vVO 2max and MSS; 3) individualised via MAS per se; 4) individualised via MSS per se; and 5) individualised using MAS and MSS as measures of locomotor capacities (LOCO). Using MSS in isolation resulted in 61 % and 39 % of player's % HSR and % VHSR, respectively, being incorrectly interpreted, when compared to the IND technique. Estimating the RCT from fractional values of MAS resulted in erroneous interpretations of % HSR in 50 % of cases. The present results suggest that practitioners and researchers should avoid using singular fitness characteristics to individualise the intensity distribution of time-motion analysis data. A combination of players' anaerobic threshold, MAS, and MSS characteristics are recommended to individualise player-tracking data

The Nature of the Low-Metallicity ISM in the Dwarf Galaxy NGC 1569

We are modeling the spectra of dwarf galaxies from infrared to submillimeter wavelengths to understand the nature of the various dust components in low-metallicity environments, which may be comparable to the ISM of galaxies in their early evolutionary state. The overall nature of the dust in these environments appears to differ from those of higher metallicity starbursting systems. Here, we present a study of one of our sample of dwarf galaxies, NGC 1569, which is a nearby, well-studied starbursting dwarf. Using ISOCAM, IRAS, ISOPHOT and SCUBA data with the Desert et al. (1990) model, we find consistency with little contribution from PAHs and Very Small Grains and a relative abundance of bigger colder grains, which dominate the FIR and submillimeter wavelengths. We are compelled to use 4 dust components, adding a very cold dust component, to reproduce the submillimetre excess of our observations.Comment: 4 pages, 4 postscript figures. Proceedings of "Infrared and Submillimeter Astronomy. An International Colloquium to Honor the Memory of Guy Serra" (2002

Central Control of Brown Adipose Tissue Thermogenesis

Thermogenesis, the production of heat energy, is an essential component of the homeostatic repertoire to maintain body temperature during the challenge of low environmental temperature and plays a key role in elevating body temperature during the febrile response to infection. Mitochondrial oxidation in brown adipose tissue (BAT) is a significant source of neurally regulated metabolic heat production in many species from mouse to man. BAT thermogenesis is regulated by neural networks in the central nervous system which responds to feedforward afferent signals from cutaneous and core body thermoreceptors and to feedback signals from brain thermosensitive neurons to activate BAT sympathetic nerve activity. This review summarizes the research leading to a model of the feedforward reflex pathway through which environmental cold stimulates BAT thermogenesis and includes the influence on this thermoregulatory network of the pyrogenic mediator, prostaglandin E2, to increase body temperature during fever. The cold thermal afferent circuit from cutaneous thermal receptors, through second-order thermosensory neurons in the dorsal horn of the spinal cord ascends to activate neurons in the lateral parabrachial nucleus which drive GABAergic interneurons in the preoptic area (POA) to inhibit warm-sensitive, inhibitory output neurons of the POA. The resulting disinhibition of BAT thermogenesis-promoting neurons in the dorsomedial hypothalamus activates BAT sympathetic premotor neurons in the rostral ventromedial medulla, including the rostral raphe pallidus, which provide excitatory, and possibly disinhibitory, inputs to spinal sympathetic circuits to drive BAT thermogenesis. Other recently recognized central sites influencing BAT thermogenesis and energy expenditure are also described

The 158 micron (CII) mapping of galaxies: Probing the atomic medium

Using the MPE/UCB Far-infrared Imaging Fabry-Perot Interferometer (FIFI) on the Kuiper Airborne Observatory (KAO), we have made large scale maps of (CII) in the spiral galaxies NGC 6946, NGC 891, M83 and the peculiar elliptical Cen A, thus allowing for the first time, detailed studies of the spatial distribution of the FIR line emission in external galaxies. We find that the (CII) emission comes from a mixture of components of interstellar gas. The brightest emission is associated with the nuclear regions, a second component traces the spiral arms as seen in the nearly face on spiral galaxies NGC 6946 and M83 and the largest star forming/H2 regions contained within them, and another extended component of low brightness can be detected in all of the galaxies far from the nucleus, beyond the extent of CO emission

Mid-infrared observations of the ultraluminous galaxies IRAS14348-1447, IRAS19254-7245, and IRAS23128-5919

We present a study of the three ultraluminous infrared galaxies IRAS14348-1447, IRAS19254-7245, and IRAS23128-5919, based on mid-infrared (MIR) spectro-imaging (5-18microns) observations performed with ISOCAM. We find that the MIR emission from each system, which consists of a pair of interacting late type galaxies, is principally confined to the nuclear regions with diameters of 1-2kpc and can account for more than 95% of their IRAS 12micron flux. In each interacting system, the galaxy hosting an active galactic nucleus (AGN) dominates the total spectrum and shows stronger dust continuum (12-16microns) relative to the Unidentified Infrared Band (UIB) emission (6-9microns), suggestive of its enhanced radiation field. The MIR dominant galaxy also exhibits elevated 15micron/Halpha and 15micron/K ratios which trace the high extinction due to the large quantities of molecular gas and dust present in its central regions. Using only diagnostics based on our mid-infrared spectra, we can establish that the Seyfert galaxy IRAS19254-7245 exhibits MIR spectral features of an AGN while the MIR spectrum of the Seyfert (or LINER) member of IRAS23128-5919 is characteristic of dust emission principally heated by star forming regions.Comment: Accepted for publication in Astronomy & Astrophysics, 13 pages, 9 figure