Quantum statistics and locality

It is shown that two observers have mutually commuting observables if they are able to prepare in each subsector of their common state space some state exhibiting no mutual correlations. This result establishes a heretofore missing link between statistical and locality (commensurability) properties of the observables of spacelike separated observers in relativistic quantum physics, envisaged four decades ago by Haag and Kastler. It is based on a discussion of coincidence experiments and suggests a physically meaningful quantitative measure of possible violations of Einstein causality.Comment: 3 pages, no figure

Radio Labelings of Distance Graphs

A radio $k$-labeling of a connected graph $G$ is an assignment $c$ of non negative integers to the vertices of $G$ such that $$|c(x) - c(y)| \geq k+1 - d(x,y),$$ for any two vertices $x$ and $y$, $x\ne y$, where $d(x,y)$ is the distance between $x$ and $y$ in $G$. In this paper, we study radio labelings of distance graphs, i.e., graphs with the set $\Z$ of integers as vertex set and in which two distinct vertices $i, j \in \Z$ are adjacent if and only if $|i - j| \in D$.Comment: 14 page

A unitary correlation operator method

The short range repulsion between nucleons is treated by a unitary correlation operator which shifts the nucleons away from each other whenever their uncorrelated positions are within the replusive core. By formulating the correlation as a transformation of the relative distance between particle pairs, general analytic expressions for the correlated wave functions and correlated operators are given. The decomposition of correlated operators into irreducible n-body operators is discussed. The one- and two-body-irreducible parts are worked out explicitly and the contribution of three-body correlations is estimated to check convergence. Ground state energies of nuclei up to mass number A=48 are calculated with a spin-isospin-dependent potential and single Slater determinants as uncorrelated states. They show that the deduced energy- and mass-number-independent correlated two-body Hamiltonian reproduces all "exact" many-body calculations surprisingly well.Comment: 43 pages, several postscript figures, uses 'epsfig.cls'. Submitted to Nucl. Phys. A. More information available at http://www.gsi.de/~fm

The Representation of Natural Numbers in Quantum Mechanics

This paper represents one approach to making explicit some of the assumptions and conditions implied in the widespread representation of numbers by composite quantum systems. Any nonempty set and associated operations is a set of natural numbers or a model of arithmetic if the set and operations satisfy the axioms of number theory or arithmetic. This work is limited to k-ary representations of length L and to the axioms for arithmetic modulo k^{L}. A model of the axioms is described based on states in and operators on an abstract L fold tensor product Hilbert space H^{arith}. Unitary maps of this space onto a physical parameter based product space H^{phy} are then described. Each of these maps makes states in H^{phy}, and the induced operators, a model of the axioms. Consequences of the existence of many of these maps are discussed along with the dependence of Grover's and Shor's Algorithms on these maps. The importance of the main physical requirement, that the basic arithmetic operations are efficiently implementable, is discussed. This conditions states that there exist physically realizable Hamiltonians that can implement the basic arithmetic operations and that the space-time and thermodynamic resources required are polynomial in L.Comment: Much rewrite, including response to comments. To Appear in Phys. Rev.

A Quantum Anti-Zeno Paradox

We establish an exact differential equation for the operator describing time-dependent measurements continuous in time and obtain a series solution. Suppose the projection operator $E(t) = U(t) E U^\dagger(t)$ is measured continuously from t = 0 to T, where E is a projector leaving the initial state unchanged and U(t) a unitary operator obeying U(0) = 1 and some smoothness conditions in t. We prove that the probability of always finding E(t) = 1 from t = 0 to T is unity. If $U(t) \neq 1$, the watched kettle is sure to `boil'.Comment: 10 pages,late

Biallelic Loss-of-Function Variants in BICD1 Are Associated with Peripheral Neuropathy and Hearing Loss

Hearing loss and peripheral neuropathy are two clinical entities that are genetically and phenotypically heterogeneous and sometimes co-occurring. Using exome sequencing and targeted segregation analysis, we investigated the genetic etiology of peripheral neuropathy and hearing loss in a large Ashkenazi Jewish family. Moreover, we assessed the production of the candidate protein via western blotting of lysates from fibroblasts from an affected individual and an unaffected control. Pathogenic variants in known disease genes associated with hearing loss and peripheral neuropathy were excluded. A homozygous frameshift variant in the BICD1 gene, c.1683dup (p.(Arg562Thrfs*18)), was identified in the proband and segregated with hearing loss and peripheral neuropathy in the family. The BIDC1 RNA analysis from patient fibroblasts showed a modest reduction in gene transcripts compared to the controls. In contrast, protein could not be detected in fibroblasts from a homozygous c.1683dup individual, whereas BICD1 was detected in an unaffected individual. Our findings indicate that bi-allelic loss-of-function variants in BICD1 are associated with hearing loss and peripheral neuropathy. Definitive evidence that bi-allelic loss-of-function variants in BICD1 cause peripheral neuropathy and hearing loss will require the identification of other families and individuals with similar variants with the same phenotype

Sialylation of campylobacter jejuni lipo-oligosaccharides: impact on phagocytosis and cytokine production in mice

<p>Background: Guillain-Barré syndrome (GBS) is a post-infectious polyradiculoneuropathy, frequently associated with antecedent Campylobacter jejuni (C. jejuni) infection. The presence of sialic acid on C. jejuni lipo-oligosaccharide (LOS) is considered a risk factor for development of GBS as it crucially determines the structural homology between LOS and gangliosides, explaining the induction of cross-reactive neurotoxic antibodies. Sialylated C. jejuni are recognised by TLR4 and sialoadhesin; however, the functional implications of these interactions in vivo are unknown.</p> <p>Methodology/Principal Findings: In this study we investigated the effects of bacterial sialylation on phagocytosis and cytokine secretion by mouse myeloid cells in vitro and in vivo. Using fluorescently labelled GM1a/GD1a ganglioside-mimicking C. jejuni strains and corresponding (Cst-II-mutant) control strains lacking sialic acid, we show that sialylated C. jejuni was more efficiently phagocytosed in vitro by BM-MΦ, but not by BM-DC. In addition, LOS sialylation increased the production of IL-10, IL-6 and IFN-β by both BM-MΦ and BM-DC. Subsequent in vivo experiments revealed that sialylation augmented the deposition of fluorescent bacteria in splenic DC, but not macrophages. In addition, sialylation significantly amplified the production of type I interferons, which was independent of pDC.</p> <p>Conclusions/Significance: These results identify novel immune stimulatory effects of C. jejuni sialylation, which may be important in inducing cross-reactive humoral responses that cause GBS</p&gt

A collaborative-interactive model for mental health consultation: Teacher inservice education by psychiatric clinicians

Primary prevention of emotional disorders is often cited as a goal in community mental health consultation. The daily contact with children and parents by the classroom teacher can yield effective prevention, if the teacher is appropriately prepared to act as a resource, and by clinicians given an awareness of emotional difficulties in children and their parents. Though consultation is often described as facilitative of change, typically discussions of such programs emphasize technique rather than content. Presented here is a collaborative model based upon a didactic input of humanistic psychology, upon which educator and clinician draw as they become allies in pursuit of answers to questions raised in current examples from the teacher's classroom experience. Excerpts and results of the model's effectiveness are given.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43964/1/10578_2005_Article_BF01433269.pd

Evaluation of sub-acute changes in cardiac function after cisplatin-based combination chemotherapy for testicular cancer

Long-term cardiovascular morbidity is increasingly observed in chemotherapy-treated testicular cancer survivors, but little is known of early sub-clinical changes in cardiac function. We prospectively evaluated cardiac function in testicular cancer patients by echocardiography. Systolic (Wall Motion Score Index) and diastolic (E/A-ratio and Tissue Velocity Imaging (TVI)) parameters, and serum levels of N-Terminal pro-Brain Natriuretic Peptide (NT-proBNP) were assessed before the start of chemotherapy and 1 year later. Echocardiography data were compared with an age-matched group of healthy controls. Forty-two patients treated with bleomycin, etoposide and cisplatin were evaluated (median age 27 years, range 18–50). Systolic function and E/A-ratio did not change, whereas the median TVI decreased (12.0 vs 10.0 cms−1; P=0.002). Median levels of NT-proBNP increased (5 vs 18 pmoll−1, P=0.034). Compared with controls, TVI before the start of chemotherapy was not significantly different. In conclusion, we found that at a median of 10 months after cisplatin-based treatment for testicular cancer, TVI decreased significantly, indicating a deterioration of diastolic cardiac function. Serum levels of NT-proBNP increased. The prognostic significance of these changes for future cardiovascular morbidity is not clear

Electron and Photon Scattering on Three-Nucleon Bound States

A big spectrum of processes induced by real and virtual photons on the 3He and 3H nuclei is theoretically investigated through many examples based on nonrelativistic Faddeev calculations for bound and continuum states. The modern nucleon-nucleon potential AV18 together with the three-nucleon force UrbanaIX is used. The single nucleon current is augmented by explicit pi- and rho-like two-body currents which fulfill the current continuity equation together with the corresponding parts of the AV18 potential. We also employ the Siegert theorem, which induces many-body contributions to the current operator. The interplay of these different dynamical ingredients in the various electromagnetic processes is studied and the theory is compared to the experimental data. Overall we find fair to good agreement but also cases of strong disagreement between theory and experiment, which calls for improved dynamics. In several cases we refer the reader to the work of other groups and compare their results with ours. In addition we list a number of predictions for observables in different processes which would challenge this dynamical scenario even more stringently and systematically.Comment: 154 pages, 80 figures includes as ps files, 21 additional figures as jpeg file