The biographical consequences of protest and activism: a systematic review and a new typology

Most research on activist participation has aimed to explain motives to engage in protest and collective action or becoming an activist. The outcomes, for the individual, have been neglected. Therefore, we set out to systematically document and organize the psychological and behavioural changes associated with activism into a typology of change. The review contains 57 papers describing changes. Psychological changes identified in the literature can be classified into 19 main forms: marital status, children, relationship ties, work-life/career, extended involvement, consumer behaviour, identity, empowerment, radicalization/politicization, legitimacy, sustained commitment, self-esteem, general well-being, ‘traits’, self-confidence, religion, organizing, knowledge and home skills. Our analysis highlights the lack of analysis of the relation between type of protest and type of change, and lack of research into the processes behind the various psychological changes. What is needed now is more precise investigation of the relationship between types of protests, social and psychological processes, and psychological outcomes. Further, more longitudinal studies are required to explore the relationship

Magnetostatic bias in multilayer microwires: theory and experiments

The hysteresis curves of multilayer microwires consisting of a soft magnetic nucleus, intermediate non-magnetic layers, and an external hard magnetic layer are investigated. The magnetostatic interaction between magnetic layers is proved to give rise to an antiferromagnetic-like coupling resulting in a magnetostatic bias in the hysteresis curves of the soft nucleus. This magnetostatic biasing effect is investigated in terms of the microwire geometry. The experimental results are interpreted considering an analytical model taking into account the magnetostatic interaction between the magnetic layers.Comment: 6 pages, 7 figure

Experimentally increased brood size accelerates actuarial senescence and increases subsequent reproductive effort in a wild bird population

The assumption that reproductive effort decreases somatic state, accelerating ageing, is central to our understanding of life-history variation. Maximal reproductive effort early in life is predicted to be maladaptive by accelerating ageing disproportionally, decreasing fitness. Optimality theory predicts that reproductive effort is restrained early in life to balance the fitness contribution of reproduction against the survival cost induced by the reproductive effort. When adaptive, the level of reproductive restraint is predicted to be inversely linked to the remaining life expectancy, potentially resulting in a terminal effort in the last period of reproduction. Experimental tests of the reproductive restraint hypothesis require manipulation of somatic state and subsequent investigation of reproductive effort and residual life span. To our knowledge the available evidence remains inconclusive, and hence reproductive restraint remains to be demonstrated. We modulated somatic state through a lifelong brood size manipulation in wild jackdaws and measured its consequences for age-dependent mortality and reproductive success. The assumption that lifelong increased brood size reduced somatic state was supported: Birds rearing enlarged broods showed subsequent increased rate of actuarial senescence, resulting in reduced residual life span. The treatment induced a reproductive response in later seasons: Egg volume and nestling survival were higher in subsequent seasons in the increased versus reduced broods' treatment group. We detected these increases in egg volume and nestling survival despite the expectation that in the absence of a change in reproductive effort, the reduced somatic state indicated by the increased mortality rate would result in lower reproductive output. This leads us to conclude that the higher reproductive success we observed was the result of higher reproductive effort. Our findings show that reproductive effort negatively covaries with remaining life expectancy, supporting optimality theory and confirming reproductive restraint as a key factor underpinning life-history variation

Al-B-C ternary compounds : synthesis, structure, composition and thermal stability

International audienc

Al-B-C ternary compounds : synthesis, structure, composition and thermal stability

International audienc

‘The International Teacher Leadership project,’ a case of international action research.

Copyright CARNThe paper arises from the International Teacher Leadership project, a research and development project involving researchers and practitioners in 14 European countries. The paper provides a conceptual exploration of the idea of teacher leadership and its role in educational reform, central to which is the idea that teachers, regardless of their level of power and organisational position, can engage in the leadership of enquiry-based development activity aimed at influencing their colleagues and embedding improved practices in their schools. The paper provides an outline of the project’s methodology which builds on that used in the Carpe Vitam Leadership for Learning project (Frost, 2008a). It is a form of collaborative action research which is highly developmental and discursive. It seeks to identify principles, strategies and tools that can be applied in a range of cultural settings. The paper includes a thematic analysis of the cultural contexts and policy environments of the participating countries in order to identify the obstacles to teacher leadership and to inform the nature of the support strategies employed

Multimodal tretment of intracranial aneurysm

Aneurysmal subarachnoid hemorrhage (SAH), despite improvements in imagistic and medical treatment, is still a serious disease with high rates of case mortality and morbidity (40%). Technical planning and therapy options of patients with aneurismal SAH have changed during the angioCT and 3D angiography era, and long-term outcome has significantly improved during the past few decades. However, the outcome is still determined mainly by specialist experience and severity of initial bleeding or early rebleeding

Ruptured intracranial aneurysm associated with bilateral carotid occlusive daises and venous angioma: A case report

Coexistence of a ruptured intracranial aneurysm with an internal carotid arteries carotid artery occlusion, a contralateral internal carotid artery stenoses and a intracranial venous angioma is infrequent and it suppose a complicate diagnosis and therapeutic management of either disease. We report a case who underwent a first successful microsurgical clipping of the intracranial aneurysm followed by a right carotid artery angioplasty with stenting after two months

Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort

Background β-lactam antibiotics are associated with a variety of immune-mediated or hypersensitivity reactions, including immediate (Type I) reactions mediated by antigen-specific IgE. Objective To identify genetic predisposing factors for immediate reactions to β-lactam antibiotics. Methods Patients with a clinical history of immediate hypersensitivity reactions to either penicillins or cephalosporins, which were immunologically confirmed, were recruited from allergy clinics. A genome-wide association study (GWAS) was conducted on 662 patients (the discovery cohort) with a diagnosis of immediate hypersensitivity and the main finding was replicated in a cohort of 98 Spanish cases, recruited using the same diagnostic criteria as the discovery cohort. Results GWAS identified rs71542416 within the Class II HLA region as the top hit (P = 2x10-14); this was in linkage disequilibrium with HLA-DRB1*10:01 (OR = 2.93 P = 5.4x10-7) and HLA-DQA1*01:05 (OR=2.93, P=5.4x10-7). Haplotype analysis identified that HLA-DRB1*10:01 was a risk factor even without the HLA-DQA1*01:05 allele. The association with HLA-DRB1*10:01 was replicated in another cohort, with the meta-analysis of the discovery and replication cohorts showing that HLA-DRB1*10:01 increased the risk of immediate hypersensitivity at a genome-wide level (OR = 2.96 P=4.1x10-9). No association with HLA-DRB1*10:01 was identified in 268 patients with delayed hypersensitivity reactions to β-lactams. Conclusion HLA-DRB1*10:01 predisposed to immediate hypersensitivity reactions to penicillins. Further work to identify other predisposing HLA and non-HLA loci is required. Clinical implications This novel insight into the mechanisms of immediate reactions associated with penicillins may be of use in risk stratifying patients where penicillin cannot be excluded as an etiological agent

Effect of ochratoxin A on the intestinal mucosa and mucosa-associated lymphoid tissues in broiler chickens

The immunotoxic effect of ochratoxin A (OTA) on the intestinal mucosa-associated lymphoid tissue and its cytotoxic action on the intestinal epithelium were studied in broiler chickens experimentally treated with the toxin. From the 7th day of life, 80 male broiler chickens (Ross 308) were randomly divided into four groups of 20 birds each. The three experimental groups (E1-3) were treated with OTA for 28 days (E1: 50 μg/kg body weight [bw]/day; E2: 20 μg/kg bw/day; E3: 1 μg/kg bw/day) and the fourth group served as control. Histological examination of the intestinal mucosa and immunohistochemical staining for identification of CD4+, CD8+, TCR1 and TCR2 lymphocytes in the duodenum, jejunum and ileocaecal junction were performed, and CD4+/CD8+ and TCR1/TCR2 ratios were calculated. OTA toxicity resulted in decreased body weight gain, poorer feed conversion ratio, lower leukocyte and lymphocyte count, and altered intestinal mucosa architecture. After 14 days of exposure to OTA, immunohistochemistry showed a significant reduction of the lymphocyte population in the intestinal epithelium and the lamina propria. After 28 days of exposure, an increase in the CD4+ and CD8+ values in both the duodenum and jejunum of chickens in Groups E1 and E2 was observed, but the TCR1 and TCR2 lymphocyte counts showed a significant reduction. No significant changes were observed in Group E3. The results indicate that OTA induced a decrease in leukocyte and lymphocyte counts and was cytotoxic to the intestinal epithelium and the mucosa-associated lymphoid tissue, altering the intestinal barrier and increasing susceptibility to various associated diseases