Analysis of the Scanning Tunneling Microscopy Images of the Charge Density Wave Phase in Quasi-one-dimensional Rb0.3MoO3

The experimental STM images for the CDW phase of the blue bronze RbMoO3 have been successfully explained on the basis of first-principles DFT calculations. Although the density of states near the Fermi level strongly concentrates in two of the three types of Mo atoms Mo-II and Mo-III, the STM measurement mostly probes the contribution of the uppermost O atoms of the surface, associated with the Mo-IO6 octahedra. In addition, it is found that the surface concentration of Rb atoms plays a key role in determining the surface nesting vector and hence the periodicity of the CDW modulation. Significant experimental inhomogeneities of the b* surface component of the wavevector of the modulation, probed by STM, are reported. The calculated changes in the surface nesting vector are consistent with the observed experimental inhomogeneities.Comment: 4 pages 5 Figure

The key role of CD40 ligand in overcoming tumor-induced dendritic cell dysfunction

Overcoming dendritic cell (DC) dysfunction is a prerequisite for successful active immunotherapy against breast cancer. CD40 ligand (CD40L), a key molecule in the interface between T-lymphocytes and DCs, seems to be instrumental in achieving that goal. Commenting on our data that CD40L protects circulating DCs from apoptosis induced by breast tumor products, Lenahan and Avigan highlighted the potential of CD40L for immunotherapy. We expand on that argument by pointing to additional findings that CD40L not only rescues genuine DCs but also functionally improves populations of immature antigen-presenting cells that fill the DC compartment in patients with breast cancer

Farm Management in Australia: The Way Forward

This paper summarises the outcomes of a National Workshop in Farm Management, 5-6 December 2002, organised by the University of Sydney, Faculty of Rural Management, Orange. At this Workshop leading farmers, industry leaders, corporate representatives, academics, researchers and extension officers explored the future of farm management (education, research and consultancy) in Australia. Major outcomes were that farm management practice is proceeding informally to undertake decisions supporting socially and ecologically friendly, sustainable commercial production agriculture. However the risks of lack of integration, a reductionist approach to only on-farm practice, stagnation of academic programs to respond to leading edge industry initiatives, as well as ill-defined boundaries for farm management research were identified. The analysis indicated that formal educational models, research and extension-consultancy frameworks of an holistic nature, and a multiple bottom line perspective, were appropriate avenues for the future development of farm management practice and research. Workshop participants perceived that a farm management strand emphasising business management rather than technology could be a better educational model. Also there was an emphasis in highlighting the importance of linked development and partnership amongst the different players. The Workshop created the conditions for development of networks among industry, education and consultative research.Farm Management,

Numerical and functional defects of blood dendritic cells in early- and late-stage breast cancer

The generation of antitumour immunity depends on the nature of dendritic cell (DC)–tumour interactions. These have been studied mostly by using in vitro-derived DC which may not reflect the natural biology of DC in vivo. In breast cancer, only one report has compared blood DC at different stages and no longitudinal evaluation has been performed. Here we conducted three cross-sectional and one one-year longitudinal assessments of blood DC in patients with early (stage I/II, n=137) and advanced (stage IV, n=36) disease compared to healthy controls (n=66). Patients with advanced disease exhibit markedly reduced blood DC counts at diagnosis. Patients with early disease show minimally reduced counts at diagnosis but a prolonged period (1 year) of marked DC suppression after tumour resection. While differing in frequency, DC from both patients with early and advanced disease exhibit reduced expression of CD86 and HLA-DR and decreased immunostimulatory capacities. Finally, by comparing a range of clinically available maturation stimuli, we demonstrate that conditioning with soluble CD40L induces the highest level of maturation and improved T-cell priming. We conclude that although circulating DC are compromised by loco-regional and systemic breast cancer, they respond vigorously to ex vivo conditioning, thus enhancing their immunostimulatory capacity and potential for immunotherapy

Проблемы медицинского обслуживания моряков в Украине

Стаття присвячена деяким проблемам медичного обслуговування моряків в Україні, в тому числі питанням професійних оглядів, які визначають придатність моряка по стану здоров‘я до роботи на суднах. Розглядаються проекти пропозицій до наказу, який готується і який буде регламентувати медичні огляди моряків.The article is devoted some problems of medical service of seafarers in Ukraine, in particular to the questions of professional examinations, determining the fitness of seafarer to be fit for work on ships. The projects of appendixes are examined to the preparing order, to regulating physical examinations of seafarers

Studi Komparasi Pemahaman Konsep Sistem Pernapasan Manusia Melalui Penerapan Pembelajaran Konstruktivisme Tipe Novick Dipadu Concept Map Dan Ceramah Bervariasi

This research is aim to find out the different comprehension of human respiration system concept in the Novick type of constructivism learning with concept map and the varied lecturing learning. This study was a quasi-experimental research using Post-test Only With Nonequivalent Groups research design. The sampling technique used was Cluster Sampling one. The populations of this research were all of 11th degree students of science at SMA Negeri 2 Karanganyar in academic year 2012/2013. The samples of this research were the students of 11th Imersi I as experiment group and 11th Imersi II as control group. Technique of collecting data used was a multiple choice test with reasoning, essay test, and observation sheet. The hypothesis testing was carried out using t-test. The conclusion of research that there isn\u27t different comprehension of human respiratory system concept between the Novick type of constructivism learning with concept map and the varied lecturing learning

How a network-based start-up ecosystem supports new venture performance: Management perspectives and future research.

The literature on how a start-up ecosystem has an impact on a start-up’s performance has significantly grown and contributed to the management field. Nevertheless, these theoretical developments have been scattered, inconsistent, lacking in theoretical depth. Therefore, in this review, we use three perspectives to organise the knowledge field, refine concepts and generate a prospectus for future studies. The perspectives reviewed are the Resource-Based View, Open Innovation and Social Capital Theory. The results have generally shown that the network-based start-up ecosystem contributes resources, capabilities, learning, collaboration, relationship, knowledge shared and social capital to new ventures. The influence of these benefits for new venture performance is uncertain. Conceptual development in start-up ecosystem research will gain value from management perspectives that address these benefits. We propose a plan for future studies on network-based start-ups that is oriented towards a more robust framework with which to consider the role and influence of a start-up ecosystem that goes beyond general descriptions of the positive effect of start-ups network-ecosystem on performance

Tuberculosis bovina en Colombia: aislamiento y tipificación del Micobacterium bovis en el valle de Ubaté.

A partir de 12 bovinos, procedentes del valle de Ubaté, Colombia, con lesiones sospechosas de tuberculosis, se procedió a trabajar ganglios linfáticos mediastínicos, ganglios linfáticos mesentéricos, pulmones e hígados, comprobándose por primera vez en ganaderías colombianas la tuberculosis bovina causada por Mycobacterium bovis. De las diferentes muestras se hicieron impresiones que se fijaron por calor. Las coloraciones de Gram y Azul de lactofenol fueron negativas para microorganismos Gram (más) y Gram (menos) y para hongos, respectivamente. En las impresiones teñidas con Ziehl-Neelsen, se observaron microorganismos ácido-alcohol resistentes. Se hicieron macerados de las muestras en caldo nutritivo y se cultivaron en medios diferenciales para confirmar o descartar la presencia o ausencia de otro tipo de gérmenes aeróbicos o anaeróbicos, bacteriales o micóticos, que pudieran dar origen a lesiones de tipo granulomatoso. Las diferentes suspensiones de las muestras se cultivaron en medio Lowenstein-Jensen más glicerina y Lowenstein-Jensen más piruvato de Na. Los cultivos en medios diferenciales para bacterias y hongos, se descartaron a las 120 horas por no presentar ningún tipo de crecimiento. El material cultivado en medio de Lowenstein-Jensen más piruvato de Na, empezó su desarrollo hacia los 17 días, presentándose en el medio colonias puntiformes blanco-amarillentas. Se dejaron en incubación hasta completar 60 días, tiempo necesario para un buen desarrollo A partir de estas colonias, se realizaron las pruebas bioquímicas para la tipificación de las cepas (4), en el Laboratorio de Tuberculosis del INAS. Ls pruebas bioquímicas de las cepas estudiadas y las pruebas biológicas permitieron clasificarlas como Mycobacterium bovisGanado de leche-Ganadería lech