1,255 research outputs found
Avalanche to streamer transition in particle simulations
The avalanche to streamer transition is studied and illustrated in a particle
model. The results are similar to those of fluid models. However, when
super-particles are introduced, numerical artefacts become visible. This
underscores the need of models that are hybrid in space.Comment: 2 pages, 1 figur
Role of CD56 in Normal Kidney Development and Wilms Tumorigenesis
The cell-surface glycoprotein CD56 has three major isoforms that play important roles in cell adhesion and signaling, which may promote cell proliferation, differentiation, survival, or migration. It is an important molecule in normal kidney development and acts as a key marker in Wilms tumor stem and progenitor cells. Here, we review the structural and genetic features of the CD56 glycoprotein, and summarize its roles in the normal versus diseased metanephric blastema. We discuss areas of CD56-related research that may complement or improve existing Wilms tumor treatment strategies, including the antibody-drug conjugate lorvotuzumab mertansine that binds to CD56
The Structure of Nuclear Star Clusters in Nearby Late-type Spiral Galaxies from Hubble Space Telescope Wide Field Camera 3 Imaging
We obtained Hubble Space Telescope/Wide Field Camera 3 imaging of a sample of
ten of the nearest and brightest nuclear clusters residing in late-type spiral
galaxies, in seven bands that span the near-ultraviolet to the near-infrared.
Structural properties of the clusters were measured by fitting two-dimensional
surface brightness profiles to the images using GALFIT. The clusters exhibit a
wide range of structural properties. For six of the ten clusters in our sample,
we find changes in the effective radius with wavelength, suggesting radially
varying stellar populations. In four of the objects, the effective radius
increases with wavelength, indicating the presence of a younger population
which is more concentrated than the bulk of the stars in the cluster. However,
we find a general decrease in effective radius with wavelength in two of the
objects in our sample, which may indicate extended, circumnuclear star
formation. We also find a general trend of increasing roundness of the clusters
at longer wavelengths, as well as a correlation between the axis ratios of the
NCs and their host galaxies. These observations indicate that blue disks
aligned with the host galaxy plane are a common feature of nuclear clusters in
late-type galaxies, but are difficult to detect in galaxies that are close to
face-on. In color-color diagrams spanning the near-UV through the near-IR, most
of the clusters lie far from single-burst evolutionary tracks, showing evidence
for multi-age populations. Most of the clusters have integrated colors
consistent with a mix of an old population (> 1 Gyr) and a young population
(~100-300 Myr). The wide wavelength coverage of our data provides a sensitivity
to populations with a mix of ages that would not be possible to achieve with
imaging in optical bands only.Comment: Corrected a typo in author name and affiliation for MC and corrected
a typo in the conclusio
Probing the AGN Unification Model at redshift z 3 with MUSE observations of giant Ly nebulae
A prediction of the classic active galactic nuclei (AGN) unification model is
the presence of ionisation cones with different orientations depending on the
AGN type. Confirmations of this model exist for present times, but it is less
clear in the early Universe. Here, we use the morphology of giant Ly
nebulae around AGNs at redshift z3 to probe AGN emission and therefore
the validity of the AGN unification model at this redshift. We compare the
spatial morphology of 19 nebulae previously found around type I AGNs with a new
sample of 4 Ly nebulae detected around type II AGNs. Using two
independent techniques, we find that nebulae around type II AGNs are more
asymmetric than around type I, at least at radial distances ~physical kpc
(pkpc) from the ionizing source. We conclude that the type I and type II AGNs
in our sample show evidence of different surrounding ionising geometries. This
suggests that the classical AGN unification model is also valid for
high-redshift sources. Finally, we discuss how the lack of asymmetry in the
inner parts (r30 pkpc) and the associated high values of the HeII to
Ly ratios in these regions could indicate additional sources of (hard)
ionizing radiation originating within or in proximity of the AGN host galaxies.
This work demonstrates that the morphologies of giant Ly nebulae can be
used to understand and study the geometry of high redshift AGNs on
circum-nuclear scales and it lays the foundation for future studies using much
larger statistical samples.Comment: 15 pages, 13 figures, accepted for publication in MNRA
Грошово-кредитна система Сполучених Штатів Америки
У статті розглядаються проблеми функціонування грошово-кредитної системи Сполучених Штатів Америки — однієї з найбільш розвинених країн світу. Ключові слова: центральний банк, комерційні банки, небанківські кредитні установи, грошова одиниця, грошово-кредитна система.В статье рассматриваются проблемы функционирования денежно-кредитной системы Соединенных Штатов Америки, одной из наиболее развитых стран мира. Ключевые слова: центральный банк, коммерческие банки, небанковские кредитные учреждения, денежная единица, денежно-кредитная система.The problems of functioning of the money-andcredit United States of America are examined in the article, one of the most prosperous countries world. Key words: Central bank, commercial banken, nonbanken of credit institution, money unit, gold-credit system
Stellar Kinematics and Structural Properties of Virgo Cluster Dwarf Early-Type Galaxies from the SMAKCED Project. I. Kinematically Decoupled Cores and Implications for Infallen Groups in Clusters
We present evidence for kinematically decoupled cores (KDCs) in two dwarf
early-type (dE) galaxies in the Virgo cluster, VCC 1183 and VCC 1453, studied
as part of the SMAKCED stellar absorption-line spectroscopy and imaging survey.
These KDCs have radii of 1.8'' (0.14 kpc) and 4.2'' (0.33 kpc), respectively.
Each of these KDCs is distinct from the main body of its host galaxy in two
ways: (1) inverted sense of rotation; and (2) younger (and possibly more
metal-rich) stellar population. The observed stellar population differences are
probably associated with the KDC, although we cannot rule out the possibility
of intrinsic radial gradients in the host galaxy. We describe a statistical
analysis method to detect, quantify the significance of, and characterize KDCs
in long-slit rotation curve data. We apply this method to the two dE galaxies
presented in this paper and to five other dEs for which KDCs have been reported
in the literature. Among these seven dEs, there are four significant KDC
detections, two marginal KDC detections, and one dE with an unusual central
kinematic anomaly that may be an asymmetric KDC.The frequency of occurence of
KDCs and their properties provide important constraints on the formation
history of their host galaxies. We discuss different formation scenarios for
these KDCs in cluster environments and find that dwarf-dwarf wet mergers or gas
accretion can explain the properties of these KDCs. Both of these mechanisms
require that the progenitor had a close companion with a low relative velocity.
This suggests that KDCs were formed in galaxy pairs residing in a poor group
environment or in isolation whose subsequent infall into the cluster quenched
star formation.Comment: 14 pages, accepted for publication in Ap
Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents
Deviations from the local field approximation in negative streamer heads
Negative streamer ionization fronts in nitrogen under normal conditions are
investigated both in a particle model and in a fluid model in local field
approximation. The parameter functions for the fluid model are derived from
swarm experiments in the particle model. The front structure on the inner scale
is investigated in a 1D setting, allowing reasonable run-time and memory
consumption and high numerical accuracy without introducing super-particles. If
the reduced electric field immediately before the front is >= 50kV/(cm bar),
solutions of fluid and particle model agree very well. If the field increases
up to 200kV/(cm bar), the solutions of particle and fluid model deviate, in
particular, the ionization level behind the front becomes up to 60% higher in
the particle model while the velocity is rather insensitive. Particle and fluid
model deviate because electrons with high energies do not yet fully run away
from the front, but are somewhat ahead. This leads to increasing ionization
rates in the particle model at the very tip of the front. The energy overshoot
of electrons in the leading edge of the front actually agrees quantitatively
with the energy overshoot in the leading edge of an electron swarm or avalanche
in the same electric field.Comment: The paper has 17 pages, including 15 figures and 3 table
Картографический метод в изучении территориального рекреационного неравенства
This article investigates the link between teachers' appraisal of specific interpersonal situations in classrooms and their more general interpersonal identity standard, which together form their interpersonal role identity. Using semi-structured and video-stimulated interviews, data on teachers' appraisals and interpersonal identity standards were collected and analyzed using appraisal and interpersonal circumplex theory. Results show a variety of interpersonal identity standards, although the majority of the teachers mentions standards focusing on the codes steering and being friendly. The situation “reacting to student positive behavior” evoked most appraisals that confirmed identity standards. For 13 of the 29 teachers, their identity standard matched with their appraisals. In most cases, however, this match was only to some extent (10 teachers) and sometimes not at all (six teachers). The results suggest that teachers can enhance their relationship with students by becoming more aware of the meanings teachers attach to this relationship in specific situations
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