Identity complexity and integration in lesbian, gay, bisexual and heterosexual adolescents and emerging adults: Implications for clinical practice

The present study aimed at assessing whether differences exist in identity complexity and integration between 31 lesbian, gay, and bisexual (LGB) and 33 heterosexual youths (mean age 21.47, SD = 3.27), both Italian and US. Participants completed a newly created questionnaire, the Identity Labels and Life Contexts Questionnaire (ILLCQ), which assesses the interplay between identity dimensions and life contexts. The ILLCQ assesses identity integration on three levels: (a) integration among the different domains of identity in their intersection with the various life contexts (assessed through salience and centrality); (b) integration between an individual’s self-definition and the definition of self made by others (perceived self-recognition); and (c) the integration between how the person perceives her/himself to be and the way she/he shows her/himself to others. Results suggest that identity salience varies significantly across life contexts for both LGB and heterosexual youths. The only significant difference between the LGB and heterosexual groups was higher salience and centrality of the sexual orientation domain for LGB youths. Sexuality represents a core identity domain for LGB participants, and perhaps less so for heterosexual participants. LGB youths reported lower general identity recognition from other people. Implications for clinical practice are discussed

Mosaic tetracycline resistance genes encoding ribosomal protection proteins

First reported in 2003, mosaic tetracycline resistance genes are a subgroup of the genes encoding ribosomal protection proteins (RPPs). They are formed when two or more RPP-encoding genes recombine resulting in a functional chimera. To date, the majority of mosaic genes are derived from sections of three RPP genes, tet(O), tet(W) and tet(32), with others comprising tet(M) and tet(S). In this first review of mosaic genes, we report on their structure, diversity and prevalence, and suggest that these genes may be responsible for an under-reported contribution to tetracycline resistance in bacteria

The Adirondack Chronology

The Adirondack Chronology is intended to be a useful resource for researchers and others interested in the Adirondacks and Adirondack history.https://digitalworks.union.edu/arlpublications/1000/thumbnail.jp

The analysis of bridging constructs with hierarchical clustering methods: An application to identity

When analyzing psychometric surveys, some design and sample size limitations challenge existing approaches. Hierarchical clustering, with its graphics (heat maps, dendrograms, means plots), provides a nonparametric method for analyzing factorially-designed survey data, and small samples data. In the present study, we demonstrated the advantages of using hierarchical clustering (HC) for the analysis of non-higher-order measures, comparing the results of HC against those of exploratory factor analysis. As a factorially-designed survey, we used the Identity Labels and Life Contexts Questionnaire (ILLCQ), a novel measure to assess identity as a bridging construct for the intersection of identity domains and life contexts. Results suggest that, when used to validate factorially-designed measures, HC and its graphics are more stable and consistent compared to EFA

NAVY EXPEDITIONARY ADDITIVE MANUFACTURING (NEAM) CAPABILITY INTEGRATION

This capstone report analyzes the current and future use of additive manufacturing (AM) technologies within the Department of Defense (DOD). This analysis provided the technical background necessary to develop the Additive Manufacturing Process and Analysis Tool (AMPAT). AMPAT will help stakeholders identify what AM equipment best serves warfighters and their missions in expeditionary environments. Furthermore, the tool can be used by stakeholders to identify the most advantageous dispersions of AM capabilities across the fleet and make decisions on how those capabilities should be integrated into the greater naval mission and larger DOD enterprise. A systems engineering (SE) approach was implemented to gather information on current and prospective AM methods in order to understand and define the AM system operational requirements. Additionally, an SE process was utilized to analyze alternative software options to build the tool, implement agile software development processes to develop the tool, and verify and validate that the tool met the project requirements. The study found that AMPAT successfully outputs a ranked list of AM systems recommendations based upon user-defined input parameters and weighting values. Recommendations for choosing AM equipment and developing dispersion plans for the fleet include using the AMPAT deliverable to conduct customized, iterative analysis with user-defined inputs that are tailored to specific expeditionary environments.Outstanding ThesisCivilian, Department of the NavyCivilian, Department of the NavyCivilian, Department of the NavyCivilian, Department of the ArmyCivilian, Department of the NavyApproved for public release. Distribution is unlimited

From dislocation nucleation to dislocation multiplication in ceramic nanoparticle

Magnesium oxide nanocubes are compressed along the [001] direction in situ in the transmission electron microscope. Incipient plasticity in the smaller samples is characterized by the nucleation of few 1/2{110} dislocations while a larger number of line defects is observed in larger nanocubes. Yield and flow stresses scattered stochastically above a minimum value varying as the inverse of the sample size. The upper bound is given by the reduced number of dislocation sources. Such size-dependent behaviour is justified by a detailed statistical analysis and is fully explained by the deformation mechanism

Intermittent dislocation flow in viscoplastic deformation

The viscoplastic deformation (creep) of crystalline materials under constant stress involves the motion of a large number of interacting dislocations. Analytical methods and sophisticated `dislocation-dynamics' simulations have proved very effective in the study of dislocation patterning, and have led to macroscopic constitutive laws of plastic deformation. Yet, a statistical analysis of the dynamics of an assembly of interacting dislocations has not hitherto been performed. Here we report acoustic emission measurements on stressed ice single crystals, the results of which indicate that dislocations move in a scale-free intermittent fashion. This result is confirmed by numerical simulations of a model of interacting dislocations that successfully reproduces the main features of the experiment. We find that dislocations generate a slowly evolving configuration landscape which coexists with rapid collective rearrangements. These rearrangements involve a comparatively small fraction of the dislocations and lead to an intermittent behavior of the net plastic response. This basic dynamical picture appears to be a generic feature in the deformation of many other materials. Moreover, it should provide a framework for discussing fundamental aspects of plasticity, that goes beyond standard mean-field approaches that see plastic deformation as a smooth laminar flow

Neuropsicologia e desnutrição: um estudo com crianças de 7 a 10 anos de idade, em uma comunidade carente

OBJECTIVES: to compare the neuropsychological profile of eutrophic, stunted and chronically malnourished children, and to analyse the role of socio-economic factors on the cognitive development. METHODS: seven to 10 year-old girls and boys from a poor community in São Paulo were evaluated: 27 eutrophyc, 31 stunted and 15 chronically malnourished. Neuropsychological evaluation involved cognitive functions not fully assessed in this population, such as working, declarative and non-declarative memories, attention and executive functions. Socio-economic indicators, maternal mental health and the children's behaviour at school were also evaluated. RESULTS: malnourished children had a lower score on the vocabulary test than the eutrophic and stunted groups (p s<0.05), performed worse in the visuospatial working memory task (p = 0.01), were more anxious than the stunted (p = 0.006), and despite having lower average birth weight than eutrophic children (p = 0.01), only two children as had prenatal malnutrition. Stunted children exhibited no impairment. No differences in socio-economic variables were found among groups. CONCLUSIONS: chronic malnutrition was associated to impairment of expressive speech, visual-spatial short-term memory and increased anxiety. No effects were observed in intellectual abilities, executive functions, verbal working memory, long-term memory, nor in visuoconstructive function. Preservation of the latter cognitive functions can be attributed to adequate environmental conditions and the lack of overall prenatal malnutrition.OBJETIVOS: comparar o perfil neuropsicológico de crianças eutróficas, desnutridas pregressas e crônicas, em idade escolar, e analisar o papel de fatores, socioeconômicas, no seu desenvolvimento cognitivo. MÉTODOS: foram avaliadas crianças de ambos os sexos, 27 eutróficas, 31 desnutridas pregressas e 15 desnutridas crônicas, de 7 a 10 anos de idade, de uma comunidade carente da cidade de São Paulo. A avaliação incluiu funções cognitivas pouco investigadas nessa população; memória operacional, memória declarativa e não-declarativa, atenção e funções executivas. Foram analisados também condições socioeconômicas, saúde mental materna e comportamento na escola. RESULTADOS: as crianças desnutridas crônicas tiveram pior desempenho do que as eutróficas no teste de vocabulário (p s < 0,05) e no teste de memória operacional vísuo-espacial (p = 0,01), mostraram-se mais ansiosas (p = 0,006), somente dois indivíduos tinham desnutrição pré-natal. As crianças desnutridas pregressas não mostraram prejuízos. Nas variáveis socioeconômicas não houve diferenças. CONCLUSÕES: a desnutrição crônica foi relacionada a prejuízo de linguagem expressiva, memória operacional vísuo-espacial e maior ansiedade. Não houve prejuízo de nível intelectual, funções executivas, memória de longo prazo e função vísuo-construtiva. A preservação da maioria das funções cognitivas pode ser atribuída à ausência de desnutrição intra-uterina, e/ou ao fato de que, as crianças vivem em adequado ambiente socio-econômico.Universidade Federal de São Paulo (UNIFESP) Departamento de PsicobiologiaUNIFESP, Depto. de PsicobiologiaSciEL

Renal Sympathetic Denervation and Quality of Life

ABSTRACTBackgroundRenal sympathetic denervation (RSD) is a promising strategy in the treatment of resistant hypertension. No studies have assessed the effect of RSD on quality of life in our country, which was the aim of this study.MethodsThe EuroQol5 Dimensions questionnaire (EQ5D5L) was chosen to evaluate quality of life in 10 patients undergoing RSD, and it was applied before and 3 months after the procedure.ResultsMean age was 47.3 ± 12 years and 90% of the patients were female. Baseline blood pressure was 187 ± 37.5/104 ± 18.5mmHg and the number of antihypertensive drugs was 7.6 ± 1.3. Before the procedure, the value assigned to health status was 37.5 ± 22.7, increasing at 3 months to 70.5 ± 20.9 (P = 0.01). In the follow-up, in addition to a decrease in the number of antihypertensive drugs (7.6 ± 1.3 vs. 6 ± 2.2; P = 0.05), a trend towards reduced levels of systolic blood pressure (187 ± 36mmHg vs 170 ± 44mmHg; P = 0.10) and diastolic blood pressure (104 ± 18mmHg vs 98 ± 20mmHg; P = 0.20) was observed. Health status improvement resulted from a reduction of problems related to mobility, usual activities, pain/discomfort and anxiety/depression. The magnitude of blood pressure reduction was not associated with improved quality in all of the patients. On the other hand, those who had a decrease in the number of antihypertensive drugs reported a better health status.ConclusionsPatients with resistant hypertension have poor health status scores. RSD improved quality of life in most patients. Further studies are required to confirm consistent benefits