Synthesis, characterisation and gas permeation studies on microporous silica and alumina-silica membranes for separation of propane and propylene

Microporous silica membranes are known to exhibit molecular sieving effects. However, separation of nearly equal sized molecules is difficult to carry out by size exclusion. Introducing sorption selectivity and keeping the kinetics favourable to facilitate a good contribution of permeation from sorption is a possible solution to enhance selectivity of adsorbing molecules. Results are presented in this paper on the synthesis of a microporous silica membrane with commendable permselectivity between helium and propylene. Modifications are performed on the membrane to improve its almost non-selective nature to propylene/propane mixtures to give practical separation values. Gas separation results on the modified membranes are presented. Surface selectivity on the newly added alumina surface layer is identified as the helping mechanism in realising this separation

Studies on Bracing Member End Connections for Cold Formed Steel Sections

This paper is concentrated mainly on the behaviour of bracing end connections for cold formed steel lipped angle and lipped channel sections. For bracing members, only one flange is possible to connect with tower leg member or supporting member, which causes uneven distribution of stresses in the end section popularly known as shear lag effect. Tension tests have been carried out to simulate the bracing end connections. Special test rig has been assembled and end fittings fabricated such that the load will be applied as concentric load at the pulling end and on the other end load is transferred through the connected flange only. All the specimens have been instrumented with dial gauges, to study the deformations and one specimen is instrumented with strain gauges to study the strain variation. The failure load for tested joints has been calculated by using various International Standards and compared with the test results

Searches for IceCube Neutrinos Coincident with Gravitational Wave Events

Searches for neutrinos from gravitational wave events have been performed utilizing the wide energy range of the IceCube Neutrino Observatory. We discuss results from these searches during the third observing run (O3) of the advanced LIGO and Virgo detectors, including a low-latency follow-up of public candidate alert events in O3, an archival search on high-energy track data, and a low-energy search employing IceCube-DeepCore. The dataset of high-energy tracks is mainly sensitive to muon neutrinos, while the low energy dataset is sensitive to neutrinos of all flavors. In all of these searches, we present upper limits on the neutrino flux and isotropic equivalent energy emitted in neutrinos. We also discuss future plans for additional searches, including extending the low-latency follow-up to the next observing run of the LIGO-Virgo-KAGRA detectors (O4) and analysis of gravitational wave (GW) events using a high-energy cascade dataset, which are produced by electron neutrino charged-current interactions and neutral-current interactions from neutrinos of all flavors.Comment: Presented at the 38th International Cosmic Ray Conference (ICRC2023). See arXiv:2307.13047 for all IceCube contribution

EFFECT OF VARIOUS ROOT CANAL DISINFECTION PROCEDURES ON EXPRESSION OF ENTEROCOCCUS FAECALIS VIRULENCE FACTOR – A PCR STUDY

Abstract Objective: To compare and evaluate antimicrobial effects of 2% Chlorhexidine (CHX) versus 0.1% Octenidine Dihydrochloride (OCT) as root canal irrigant with and without Laser activation against Enterococcus faecalis virulence factor - E. faecalis endocarditis antigen (efaA) using real time polymerase chain reaction. Aim: To evaluate the effect of various root canal disinfection procedures on expression of Enterococcus faecalis virulence factor (efaA) using real time PCR. Methods and Materials: Forty single rooted premolars were taken and decoronated to standardize the root length as 14 mm. The canals were instrumented up to F3 Protaper Gold and teeth were autoclaved at 121°C for 20 minutes at 15 psi. 0.1 mL of the bacterial suspension was injected into the root canals, and the samples were incubated at 37°C and 100% humidity for 21 days. The samples were randomly divided into four groups: Group I – 2% Chlorhexidine, Group - II 2% Chlorhexidine with Laser, Group III – 0.1% Octenidine dihydrochloride, Group IV- 0.1% Octenidine dihydrochloride with Laser. After the irrigation protocol, Paper points were used to transfer the contents of the canal. PCR was performed to detect the presence of Enterococcus faecalis virulence factor (efaA). Results:Octenidine (0.1%) was more effective than 2% Chlorhexidine against E. faecalis. Group II and IV showed significant difference compared to Group I and III with statistically significant difference (p˂0.001). Laser activation enhanced the antimicrobial action of the irrigants. Conclusion: Octenidine (0.1%) was more effective than 2% Chlorhexidine against E. faecalis. Laser activated irrigation proved to enhance the antimicrobial action of the irrigants

Distributed fibre optic strain sensing of an axially deformed well model in the laboratory

Well integrity is crucial in enabling sustainable gas production from methane hydrate reservoirs and real-time distributed monitoring techniques can potentially facilitate proper and timely inspection of well integrity during gas production. In this research, the feasibility of distributed fibre optic strain monitoring with Brillouin optical time domain reflectometry/analysis (BOTDR/A) for well monitoring was examined by conducting a laboratory test on a well model subjected to axial tensile deformation, which occurs due to reservoir compaction during gas production. First, the validity of the proposed experimental methodology is assessed by a finite element analysis and theoretical modelling of a well subjected to reservoir compaction. A 3 m long well model is developed from the modelling and is instrumented with different types of fibre optic cables to measure the distributed strain development during tensile loading. Results show that the proposed well model and loading scheme can satisfactorily simulate the axial tensile deformation of the well in the laboratory condition. BOTDR is capable of capturing the tensile strain development of the well model accurately within the limitation of the spatial resolution of the BOTDR measurement. To enable accurate distributed strain monitoring of well deformation with BOTDR/A, the following issues are discussed: tightly buffered coating layers around optical fibre cores through mechanical compression and/or chemical adhesion, and a small number of coating layers

Caustic Recycle from Hanford Tank Waste Using Large Area NaSICON Structures (LANS)

This report presents the results of a 5-day test of an electrochemical bench-scale apparatus using a proprietary (NAS-GY) material formulation of a (Na) Super Ion Conductor (NaSICON) membrane in a Large Area NaSICON Structures (LANS) configuration. The primary objectives of this work were to assess system performance, membrane seal integrity, and material degradation while removing Na from Group 5 and 6 tank waste from the Hanford Site

The <i>Plasmodium</i> eukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

Sporozoites, the invasive form of malaria parasites transmitted by mosquitoes, are quiescent while in the insect salivary glands. Sporozoites only differentiate inside of the hepatocytes of the mammalian host. We show that sporozoite latency is an active process controlled by a eukaryotic initiation factor-2α (eIF2α) kinase (IK2) and a phosphatase. IK2 activity is dominant in salivary gland sporozoites, leading to an inhibition of translation and accumulation of stalled mRNAs into granules. When sporozoites are injected into the mammalian host, an eIF2α phosphatase removes the PO4 from eIF2α-P, and the repression of translation is alleviated to permit their transformation into liver stages. In IK2 knockout sporozoites, eIF2α is not phosphorylated and the parasites transform prematurely into liver stages and lose their infectivity. Thus, to complete their life cycle, Plasmodium sporozoites exploit the mechanism that regulates stress responses in eukaryotic cells