On effective index approximations of photonic crystal slabs

As a means to assess the quality of effective index approximations in simulations of photonic crystal slabs, we consider a reduction of 2-D Helmholtz problems for waveguide Bragg gratings to 1-D wave propagation, and compare with rigorous 2-D reference solutions. Variational procedures permit to establish a reasonable effective index profile even in cases where locally no guided modes exist

Effects of Cold Deformation and Electron Irradiations on Deuterium Desorption Temperature Range from Zr – 1 %Nb Alloy

The explored warm-up ranges of desorption ion-implanted deuterium from Zr – 1 %Nb alloy, with different structure: after crystallization from melt, plastic deformation and irradiations electron. Cool deformation under 300 K Zr – 1 %Nb alloy with degree 3.9 has allowed to reach the nanostructure conditions in alloy with average size crystallite d 61 nm, high three-dimensional concentration of the borders (~ 3,4 %) and significant level microstrain that in spectrum of thermodesorption ion-implanted deuterium was shown as additional low temperature area thermodesorption deuterium within the range of the temperature 770-1000 K. Irradiation electron to energy 10 MeV by fluence ~ 6 × 1017 cm – 2 has brought about active development of the revocable processes in nanostructure alloy: reduction of the average grain size d 58 nm, increase to concentrations of the borders (~ 8,8 %) and appearance additional peaks in spectrum of thermodesorption deuterium with the temperature 700 and 800 K and, accordingly, increase the warmup range desorption deuterium toward reduction of the temperature. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3512

Microarray study of gene expression in uterine leiomyoma

Uterine leiomyoma is a most common benign neoplasm in women of reproductive age. It arises from the myometrial compartment of the uterus and may transform in some cases to a malignant phenotype. Aim: To identify the genes involved in pathogenesis of uterine leiomyoma. Methods: We have studied differential gene expression in matched tissue samples of leiomyoma and normal myometrium from the very same people utilizing a cDNA microarray screening method. We also compared our results with previously published microarray data to identify the overlapping gene alterations. Results: Based on this comparison we can divide genes deregulated in our study into two groups. The first group comprises genes that to our knowledge have not been previously reported as deregulated in fibroids: CLDN1, FGF7 (KGF), HNRPM, ISOC1, MAGEC1 (CT7), MAPK12, RFC, TIE1, TNFRSF21 (DR6). The second group consists of genes identified also in previous studies: CCND1 (BCL1), CDKN1A (P21), CRABP2, FN1 and SOX4 (EVI16). In our study FN1 was the most up-regulated gene, occupying the place between the myometrium and fibroids ranging from 2.07 to 3.64, depending of the probe molecule used for detection. Conclusions: Newly identified genes may be regarded as potential diagnostic or prognostic markers of uterine leiomyoma and thus may be very useful as new therapeutic candidates.Лейомиома матки является одним из наиболее распространенных доброкачественных новообразований женской репродуктивной сферы. В некоторых случаях отмечают злокачественную трансформацию данного новообразования. Цель: идентификация генов, вовлеченных в патогенез лейомиомы. Методы: проведен анализ дифференциальной экспрессии генов в образцах лейомиомы и нормального миометрия одних и тех же пациентов методом ДНК-биочип-гибридизации и проведено сравнение полученных результатов с данными, опубликованными ранее. Результаты: выявлены различия в экспрессии ряда генов, которые можно разделить на две группы. Впервые выявлена повышенная экспрессия генов CLDN1, FGF7 (KGF), HNRPM, ISOC1, MAGEC1 (CT7), MAPK12, RFC, TIE1 и TNFRSF21 (DR6) в ткани лейомиомы по сравнению с нормальным миометрием. Ко второй группе можно отнести гены CCND1 (BCL1), CDKN1A (P21), CRABP2, FN1 и SOX4 (EVI16), уже упоминавшиеся в связи с патогенезом лейомиомы в ряде предыдущих исследований. Наибольшим изменением уровня экспрессии (в 2,07–3,64 раз в зависимости от зонда) характеризовался ген фибронектина FN1. Выводы: идентифицированные гены могут рассматриваться в качестве потенциальных диагностических и прогностических маркеров лейомиомы матки

(k,1)-coloring of sparse graphs

AbstractA graph G is (k,1)-colorable if the vertex set of G can be partitioned into subsets V1 and V2 such that the graph G[V1] induced by the vertices of V1 has maximum degree at most k and the graph G[V2] induced by the vertices of V2 has maximum degree at most 1. We prove that every graph with maximum average degree less than 10k+223k+9 admits a (k,1)-coloring, where k≥2. In particular, every planar graph with girth at least 7 is (2,1)-colorable, while every planar graph with girth at least 6 is (5,1)-colorable. On the other hand, when k≥2 we construct non-(k,1)-colorable graphs whose maximum average degree is arbitrarily close to 14k4k+1

Prevention of stomatological complications in therapy of locally extended cancer of oral cavity mucus

Aim of the investigation: to improve prophylaxis of dental complications during the therapy in the patients with locally extended cancer of oral cavity mucus. Materials and methods. Results of sanation of oral cavity in 320 patients with cancer of oral and pharyngeal areas have been analyzed. Results. The best results have been marked in the patients who experienced surgical sanation before chemo-radial therapy. Most complications have been observed when teeth were extracted after the chemical therapy during the period of radial therapy at focal dose of above 20 Gy as well as in the late periods after the radial therapy. Conclusion: A complex of preventive measures with the use of haemostatic sponge with canamycin in such patients has decreased a number of complications and the terms of healing of alveoli of extracted teeth

Analysis of color properties of raster images of histological microspecimens: own research experience

Analysis of color properties of raster images of histological microspecimens: own research experience. Ivanova M.D., Myroshnychenko M.S., Khara G.I., Arseniev O.V., Olkhovsky V.O., Grygorian E.K., Fedulenkova Yu.Ya., Kozlov S.V. This study is aimed to develop a computer program to analyze the color properties of raster images of histological microspecimens used in pathological anatomy and forensic medicine. When developing a computer program, we used the system for building client applications – Windows Presentation Foundation (WPF). The system allows you to create applications with visually attractive user interaction capabilities. The programming language is C#, as well as basic graphics capabilities of the .NET Framework system are used. To speed up the display we applied double buffering. In the course of the research, the authors developed a modern computer program «Analysis of color properties of raster images». This program allows you to analyze the color of each individual pixel of a photograph in RGB and Lab color models, comparing the colors and brightness of individual pixels, selecting groups of points and determining statistical characteristics of them. Characteristic points are well distinguishable in the photographs, studied with the program «Analysis of color properties of raster images». This makes it possible to select and automate these properties, using computer recognition algorithms, completely removing human factor’s influence on the analysis results. The computer program «Analysis of color properties of raster images» is of significant scientific and practical interest for specialists both in the field of morphology (pathologists, forensic experts, etc.), and in the field of other biomedical disciplines