696 research outputs found
Uniqueness and Generalization in Organizational Psychology: Research as a Relational Practice
The paper addresses the epistemological and theoretical assumptions that underpin the concept of Work and Organizational Psychology as idiographic, situated, and transformative social science. Positioning the connection between uniqueness and generalization inside the debate around organization studies as applied approaches, the contribution highlights the ontological, gnoseological, and methodological implications at stake. The use of practical instead of scientific rationality is explored, through the perspective of a hermeneutic lens, underlining the main features connected to the adoption of an epistemology of practice. Specifically, the contribution depicts the configuration of the applied research as a relational practice, embedded in the unfolding process of generating knowledge dealing with concrete social contexts and particular social objects. The discussion of a case study regarding a field research project allows one to point out challenges and constraints connected to the enactment of the research process as a social accomplishment
Learning soft task priorities for control of redundant robots
Movement primitives (MPs) provide a powerful
framework for data driven movement generation that has been
successfully applied for learning from demonstrations and robot
reinforcement learning. In robotics we often want to solve a
multitude of different, but related tasks. As the parameters
of the primitives are typically high dimensional, a common
practice for the generalization of movement primitives to new
tasks is to adapt only a small set of control variables, also
called meta parameters, of the primitive. Yet, for most MP
representations, the encoding of these control variables is precoded
in the representation and can not be adapted to the
considered tasks. In this paper, we want to learn the encoding of
task-specific control variables also from data instead of relying
on fixed meta-parameter representations. We use hierarchical
Bayesian models (HBMs) to estimate a low dimensional latent
variable model for probabilistic movement primitives (ProMPs),
which is a recent movement primitive representation. We show
on two real robot datasets that ProMPs based on HBMs
outperform standard ProMPs in terms of generalization and
learning from a small amount of data and also allows for an
intuitive analysis of the movement. We also extend our HBM by
a mixture model, such that we can model different movement
types in the same dataset
Miniaturized and High-Throughput Assays for Analysis of T-Cell Immunity Specific for Opportunistic Pathogens and HIV
Monitoring of antigen-specific T-cell responses is valuable in numerous conditions that include infectious diseases, vaccinations, and opportunistic infections associated with acquired or congenital immune defects. A variety of assays that make use of peripheral lymphocytes to test activation markers, T-cell receptor expression, or functional responses are currently available. The last
group of assays calls for large numbers of functional lymphocytes. The number of cells increases with the number of antigens to be tested. Consequently, cells may be the limiting factor, particularly in lymphopenic subjects and in children, the groups that more often require immune monitoring. We have developed immunochemical assays that measure secreted cytokines in the same wells in which peripheral blood mononuclear cells (PBMC) are cultured. This procedure lent itself to miniaturization and automation. Lymphoproliferation and the enzyme-linked immunosorbent spot (ELISPOT) assay have been adapted to a miniaturized format. Here we provide examples of immune profiles and describe a comparison between miniaturized assays based on cytokine secretion or proliferation. We also demonstrate that these assays are convenient for use in testing antigen specificity in
established T-cell lines, in addition to analysis of PBMC. In summary, the applicabilities of miniaturization to save cells and reagents and of automation to save time and increase accuracy were demonstrated in this study using different methodological approaches valuable in the clinical immunology laboratory
Conventional and algorithmic music listening before radiotherapy treatment: A randomized controlled pilot study
Music listening is a widespread approach in the field of music therapy. In this study, the effects of music listening on anxiety and stress in patients undergoing radiotherapy are investigated. Sixty patients with breast cancer who were candidates for postoperative curative radiotherapy were recruited and randomly assigned to three groups: Melomics-Health (MH) group (music listening algorithmically created, n = 20); individualized music listening (IML) group (playlist of preferred music, n = 20); no music group (n = 20). Music listening was administered for 15 min immediately before simulation and during the first five radiotherapy sessions. The State-Trait Anxiety Inventory (STAI) and the Psychological Distress Inventory (PDI) were administered before/after treatment. Cochran’s Q test and McNemar test for paired proportions were performed to evaluate if the proportion of subjects having an outcome score below the critical value by treatment and over time was different, and if there was a change in that proportion. The MH group improved in STAI and PDI. The IML group worsened in STAI at T1 and improved STAI-Trait at T2. The IML group worsened in PDI at T2. The No music group generally improved in STAI and PDI. Clinical and music listening-related implications are discussed defining possible research perspectives in this field
Anemia a cellule falciformi e sindromi correlate: aggiornamenti e prospettive
The presence of hemoglobin S (HbS) in blood is responsible for sickle cell disease when its concentration, for the presence of two copies of HbS gene or one copy of HbS plus another \u3b2-globin variant (such as hemoglobin C or \u3b2-thalassemia), is markedly increased. In this report, we reviewed some recent epidemiological data on the disease prevalence, we discussed pre-analytical as well analytical aspects, relevant to the correct measurement of HbS in blood, and we summarized some important aspects for the management of the sickling crises and for the current and future therapy of this disease
Learning high-level robotic manipulation actions with visual predictive model
Learning visual predictive models has great potential for real-world robot manipulations. Visual predictive models serve as a model of real-world dynamics to comprehend the interactions between the robot and objects. However, prior works in the literature have focused mainly on low-level elementary robot actions, which typically result in lengthy, inefficient, and highly complex robot manipulation. In contrast, humans usually employ top–down thinking of high-level actions rather than bottom–up stacking of low-level ones. To address this limitation, we present a novel formulation for robot manipulation that can be accomplished by pick-and-place, a commonly applied high-level robot action, through grasping. We propose a novel visual predictive model that combines an action decomposer and a video prediction network to learn the intrinsic semantic information of high-level actions. Experiments show that our model can accurately predict the object dynamics (i.e., the object movements under robot manipulation) while trained directly on observations of high-level pick-and-place actions. We also demonstrate that, together with a sampling-based planner, our model achieves a higher success rate using high-level actions on a variety of real robot manipulation tasks
- …