161 research outputs found

    Lyα\alpha at Cosmic Dawn with a Simulated Roman Grism Deep Field

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    The slitless grism on the Nancy Grace Roman Space Telescope will enable deep near-infrared spectroscopy over a wide field of view. We demonstrate Roman's capability to detect Lyα\alpha galaxies at z>7z>7 using a multi-position-angle (PA) observational strategy. We simulate Roman grism data using a realistic foreground scene from the COSMOS field. We also input fake Lyα\alpha galaxies spanning redshift z=7.5-10.5 and a line-flux range of interest. We show how a novel data cube search technique -- CUBGRISM -- originally developed for GALEX can be applied to Roman grism data to produce a Lyα\alpha flux-limited sample without the need for continuum detections. We investigate the impact of altering the number of independent PAs and exposure time. A deep Roman grism survey with 25 PAs and a total exposure time of 7070hrs can achieve Lyα\alpha line depths comparable to the deepest z=7z=7 narrow-band surveys (LLyα1043L_{{\rm{Ly}}\alpha}\gtrsim10^{43}erg s1^{-1}). Assuming a null result, where the opacity of the intergalactic medium (IGM) remains unchanged from z7z\sim7, this level of sensitivity will detect 400\sim400 deg2^{-2} Lyα\alpha emitters from z=7.258.75z=7.25-8.75. A decline from this expected number density is the signature of an increasing neutral hydrogen fraction and the onset of reionization. Our simulations indicate that a deep Roman grism survey has the ability to measure the timing and magnitude of this decline, allowing us to infer the ionization state of the IGM and helping us to distinguish between models of reionization.Comment: 11 pages, 7 figures, Submitted to Ap

    Probing Patchy Reionization with the Void Probability Function of Lyman-α\alpha Emitters

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    We probe what constraints for the global ionized hydrogen fraction the Void Probability Function (VPF) clustering can give for the Lyman-Alpha Galaxies in the Epoch of Reionization (LAGER) narrowband survey as a function of area. Neutral hydrogen acts like a fog for Lyman-alpha emission, and measuring the drop in the luminosity function of Lyman-α\alpha emitters (LAEs) has been used to constrain the ionization fraction in narrowband surveys. However, the clustering of LAEs is independent from the luminosity function's inherent evolution, and can offer additional constraints for reionization under different models. The VPF measures how likely a given circle is to be empty. It is a volume-averaged clustering statistic that traces the behavior of higher order correlations, and its simplicity offers helpful frameworks for planning surveys. Using the \citet{Jensen2014} simulations of LAEs within various amount of ionized intergalactic medium, we predict the behavior of the VPF in one (301x150.5x30 Mpc3^3), four (5.44×106\times 10^6 Mpc3^3), or eight (1.1×107\times 10^7 Mpc3^3) fields of LAGER imaging. We examine the VPF at 5 and 13 arcminutes, corresponding to the minimum scale implied by the LAE density and the separation of the 2D VPF from random, and the maximum scale from the 8-field 15.5 deg2^2 LAGER area. We find that even a single DECam field of LAGER (2-3 deg2^2) could discriminate between mostly neutral vs. ionized. Additionally, we find four fields allows the distinction between 30, 50, and 95 percent ionized; and that eight fields could even distinguish between 30, 50, 73, and 95 percent ionized.Comment: 14 pages, 5 figure

    VLA 1.4 GHz Catalogs of the Abell 370 and Abell 2390 Cluster Fields

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    We present 1.4 GHz catalogs for the cluster fields Abell 370 and Abell 2390 observed with the Very Large Array. These are two of the deepest radio images of cluster fields ever taken. The Abell 370 image covers an area of 40'x40' with a synthesized beam of ~1.7" and a noise level of ~5.7 uJy near field center. The Abell 2390 image covers an area of 34'x34' with a synthesized beam of ~1.4" and a noise level of ~5.6 uJy near field center. We catalog 200 redshifts for the Abell 370 field. We construct differential number counts for the central regions (radius < 16') of both clusters. We find that the faint (S_1.4GHz < 3 mJy) counts of Abell 370 are roughly consistent with the highest blank field number counts, while the faint number counts of Abell 2390 are roughly consistent with the lowest blank field number counts. Our analyses indicate that the number counts are primarily from field radio galaxies. We suggest that the disagreement of our counts can be largely attributed to cosmic variance.Comment: 13 pages, accepted for publication in ApJ

    The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.

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    Summary Trained immunity (TI) is a de facto innate immune memory program induced in monocytes/macrophages by exposure to pathogens or vaccines, which evolved as protection against infections. TI is characterized by immunometabolic changes and histone post-translational modifications, which enhance production of pro-inflammatory cytokines. As aberrant activation of TI is implicated in inflammatory diseases, tight regulation is critical; however, the mechanisms responsible for this modulation remain elusive. Interleukin-37 (IL-37) is an anti-inflammatory cytokine that curbs inflammation and modulates metabolic pathways. In this study, we show that administration of recombinant IL-37 abrogates the protective effects of TI in vivo, as revealed by reduced host pro-inflammatory responses and survival to disseminated candidiasis. Mechanistically, IL-37 reverses the immunometabolic changes and histone post-translational modifications characteristic of TI in monocytes, thus suppressing cytokine production in response to infection. IL-37 thereby emerges as an inhibitor of TI and as a potential therapeutic target in immune-mediated pathologies

    The HETDEX Survey: Emission Line Exploration and Source Classification

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    The Hobby-Eberly Telescope Dark Energy Experiment (HETDEX) is an untargeted spectroscopic survey that aims to measure the expansion rate of the Universe at z2.4z \sim 2.4 to 1% precision for both H(z)H(z) and DA(z)D_A(z). HETDEX is in the process of mapping in excess of one million Lyman Alpha emitting (LAE) galaxies and a similar number of lower-z galaxies as a tracer of the large-scale structure. The success of the measurement is predicated on the post-observation separation of galaxies with Lyα\alpha emission from the lower-zz interloping galaxies, primarily [OII], with low contamination and high recovery rates. The Emission Line eXplorer (ELiXer) is the principal classification tool for HETDEX, providing a tunable balance between contamination and completeness as dictated by science needs. By combining multiple selection criteria, ELiXer improves upon the 20 Angstrom rest-frame equivalent width cut commonly used to distinguish LAEs from lower-zz [OII] emitting galaxies. Despite a spectral resolving power, R 800\sim800, that cannot resolve the [OII] doublet, we demonstrate the ability to distinguish LAEs from foreground galaxies with 98.1% accuracy. We estimate a contamination rate of Lyα\alpha by [OII] of 1.2% and a Lyα\alpha recovery rate of 99.1% using the default ELiXer configuration. These rates meet the HETDEX science requirements.Comment: 38 pages, 11 figure

    De-Novo Assembly and Analysis of the Heterozygous Triploid Genome of the Wine Spoilage Yeast Dekkera bruxellensis AWRI1499

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    Despite its industrial importance, the yeast species Dekkera (Brettanomyces) bruxellensis has remained poorly understood at the genetic level. In this study we describe whole genome sequencing and analysis for a prevalent wine spoilage strain, AWRI1499. The 12.7 Mb assembly, consisting of 324 contigs in 99 scaffolds (super-contigs) at 26-fold coverage, exhibits a relatively high density of single nucleotide polymorphisms (SNPs). Haplotype sampling for 1.2% of open reading frames suggested that the D. bruxellensis AWRI1499 genome is comprised of a moderately heterozygous diploid genome, in combination with a divergent haploid genome. Gene content analysis revealed enrichment in membrane proteins, particularly transporters, along with oxidoreductase enzymes. Availability of this assembly and annotation provides a resource for further investigation of genomic organization in this species, and functional characterization of genes that may confer important phenotypic traits

    The Lick AGN Monitoring Project 2016 : dynamical modeling of velocity-resolved Hβ lags in luminous Seyfert galaxies

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    K.H. acknowledges support from STFC grant ST/R000824/1.We have modeled the velocity-resolved reverberation response of the Hβ broad emission line in nine Seyfert 1 galaxies from the Lick Active Galactic Nucleus (AGN) Monitoring Project 2016 sample, drawing inferences on the geometry and structure of the low-ionization broad-line region (BLR) and the mass of the central supermassive black hole. Overall, we find that the Hβ BLR is generally a thick disk viewed at low to moderate inclination angles. We combine our sample with prior studies and investigate line-profile shape dependence, such as log10(FWHM/σ), on BLR structure and kinematics and search for any BLR luminosity-dependent trends. We find marginal evidence for an anticorrelation between the profile shape of the broad Hβ emission line and the Eddington ratio, when using the rms spectrum. However, we do not find any luminosity-dependent trends, and conclude that AGNs have diverse BLR structure and kinematics, consistent with the hypothesis of transient AGN/BLR conditions rather than systematic trends.Publisher PDFPeer reviewe
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