Scale effect in a LUTI model of Brussels: challenges for policy evaluation

The aim of this paper is to assess the reliability of policy evaluation based on Land Use and Transport Interactions models, relative to the choice of the Basic Spatial Units. An UrbanSim (+ MATsim) model applied to Brussels (Belgium) is used as the case study. The evolution of the study area over twenty years is forecasted for four levels of Basic Spatial Units and five scenarios (businessas-usual and four alternatives). Results show larger variations between Basic Spatial Units levels than across scenarios. These findings are valid for various sustainability indicators and for a simple cost-benefit analysis aiming at ranking the scenarios. The direction of the variations resulting from the implementation of the scenarios remains, however, the same for all Basic Spatial Units levels. Hence, the influence of the scale on policy evaluation based on Land Use and Transport Interactions models appears limited when it is only intended to compare scenarios, but it will have a crucial role when evaluations are based on absolute variations or threshold values

Blip10000: a social video dataset containing SPUG content for tagging and retrieval

The increasing amount of digital multimedia content available is inspiring potential new types of user interaction with video data. Users want to easilyfind the content by searching and browsing. For this reason, techniques are needed that allow automatic categorisation, searching the content and linking to related information. In this work, we present a dataset that contains comprehensive semi-professional user generated (SPUG) content, including audiovisual content, user-contributed metadata, automatic speech recognition transcripts, automatic shot boundary les, and social information for multiple `social levels'. We describe the principal characteristics of this dataset and present results that have been achieved on different tasks

The flow of a foam in a two-dimensional porous medium

International audienceFoams have been used for decades as displacing fluids for enhanced oil recovery and aquifer remediation, and more recently, for remediation of the vadose zone, in which case foams carry chemical amendments. Foams are better injection fluids than aqueous solutions due to their low sensitivity to gravity and because they are less sensitive to permeability heterogeneities, thus allowing a more uniform sweep. The latter aspect results from their peculiar rheology, whose understanding motivates the present study. We investigate foam flow through a two-dimensional porous medium consisting of circular obstacles positioned randomly in a horizontal transparent Hele-Shaw cell. The local foam structure is recorded in situ, which provides a measure of the spatial distribution of bubble velocities and sizes at regular time intervals. The flow exhibits a rich phenomenology including preferential flow paths and local flow nonstationarity (intermittency) despite the imposed permanent global flow rate. Moreover, the medium selects the bubble size distribution through lamella division-triggered bubble fragmentation. Varying the mean bubble size of the injected foam, its water content, and mean velocity, we characterize those processes systematically. In particular, we measure the spatial evolution of the distribution of bubble areas, and infer the efficiency of bubble fragmentation depending on the various control parameters. We furthermore show that the distributions of bubble sizes and velocities are correlated. This study sheds new light on the local rheology of foams in porous media and opens the way toward quantitative characterization of the relationship between medium geometry and foam flow properties. It also suggests that large-scale models of foam flows in the subsurface should account for the correlation between bubble sizes and velocities

Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects

<p>Abstract</p> <p>Background</p> <p>Consumption of plant sterol (PS) esters lower low-density lipoprotein (LDL)-cholesterol levels by suppressing intestinal absorption of cholesterol. Commercially available PS are mainly esterified to omega-6 fatty acid (FA), such as sunflower oil (SO) FA. Emerging trends include using other sources such as olive oil (OO) or omega-3 FA from fish oil (FO), known to exert potent hypotriglyceridemic effects. Our objective was to compare the actions of different FA esterified to PS on blood lipids, carotenoid bioavailability as well as inflammatory and coagulation markers.</p> <p>Methods</p> <p>Twenty-one moderately overweight, hypercholesterolemic subjects consumed experimental isoenergetic diets enriched with OO (70% of fat), each lasting 28-day and separated by 4-week washout periods, using a randomized crossover design. Diets were supplemented with three PS esters preparations, PS-FO, PS-SO, or PS-OO. All PS treatments contained an equivalent of 1.7 PS g/d, and the PS-FO provided a total of 5.4 g/d FO FA (eicosapentaenoic and docosahexaenoic acids).</p> <p>Results</p> <p>There were no differences between PS-containing diet effects on total cholesterol, LDL-cholesterol, or high-density lipoprotein (HDL)-cholesterol levels. However, PS-FO consumption resulted in markedly lower (P < 0.0001) fasting and postprandial triglyceride concentrations compared with PS-SO and PS-OO. These treatments affected plasma β-carotene (P = 0.0169) and retinol (P = 0.0244), but not tocopherol (P = 0.2108) concentrations. Consumption of PS-FO resulted in higher β-carotene (P = 0.0139) and retinol (P = 0.0425) levels than PS-SO and PS-OO, respectively. Plasma TNF-α, IL-6, C-reactive protein, prostate specific antigen, and fibrinogen concentrations were unaffected by the PS-interventions. In contrast, plasminogen activator inhibitor 1 (PAI-1) concentrations were lower (P = 0.0282) in the PS-FO-fed than the PS-SO, but not the PS-OO (P = 0.7487) groups.</p> <p>Conclusion</p> <p>Our findings suggest that, in hypercholesterolemic subjects consuming an OO-based diet, PS-FO results in lowered blood triglyceride and PAI-1 concentrations, and higher fat-soluble vitamin levels in comparison to the vegetable oil FA esters of PS (PS-SO and PS-OO). Thus, PS-FO may offer hyperlipidemic subjects a more comprehensive lipid lowering approach while reducing the potential risk of decreased plasma carotenoid concentrations.</p

Seasonal modulation of mesoscale processes alters nutrient availability and plankton communities in the Red Sea

Hydrographic and atmospheric forcing set fundamental constraints on the biogeochemistry of aquatic ecosystems and manifest in the patterns of nutrient availability and recycling, species composition of communities, trophic dynamics, and ecosystem metabolism. In the Red Sea, latitudinal gradients in environmental conditions and primary production have been ascribed to fluctuations in Gulf of Aden Water inflow, upwelling/mixing, and regenerated nutrient utilization i.e. rapidly recycled nitrogen in upper layers. However, our understanding of upper layer dynamics and related changes in plankton communities, metabolism and carbon and nitrogen export is limited. We surmised that stratification and mesoscale eddies modulate the nutrient availability and taxonomic identity of plankton communities in the Red Sea. Based on remote-sensing data of sea level anomalies and high resolution in situ measurements (ScanFish) we selected stations for hydrographic CTD profiles, water sampling (nutrients, seawater oxygen stable isotopes [δ18OSW]), phytoplankton and zooplankton collections. In fall 2014, strong stratification subjected the plankton community to an overall nitrogen and phosphorus shortage. The nutrient deficiency increased numbers of heterotrophic dinoflagellates, microzooplankton, and diazotrophs (Trichodesmium, diatom-diazotroph associations [DDAs]), albeit largely decreased phytoplankton and mesozooplankton abundances. In spring 2015, mesoscale eddies increased the nutrient availability, and the thermohaline characteristics and low δ18OSW point to the interaction of eddies with Gulf of Aden Surface Water (GASW). Cyclonic eddies and, most likely, the availability of nutrients associated with the GASW, increased the abundances of autotrophs (diatoms, Prasinophytes) and supported larger numbers of zooplankton and their larvae. We demonstrate that the interplay of stratification, advection of Gulf of Aden water and mesoscale eddies are key elements to better understand changes in plankton community composition, ecosystem metabolism, and macronutrient export in the Red Sea in space and time

Améliorer la compréhension et la gestion des conflits d’intérêts des experts conseillant la prise de décisions en santé publique

Étude de cas / Case studyAu Québec, au Canada et ailleurs dans le monde, des comités consultatifs d’experts conseillent et orientent les décideurs gouvernementaux dans le choix de nouveaux médicaments, de vaccins à utiliser ou encore d’interventions à mettre en place. Parallèlement, ces experts bénéficient d’un appui de plus en plus important d’entreprises privées pour réaliser leurs recherches ou en diffuser les résultats. Cette situation les met à risque de conflits d’intérêts et peut, éventuellement, miner la confiance de la population envers la prise de décision publique. Cette étude de cas suscite des réflexions pertinentes quant à ce qui constitue une gestion saine et optimale des situations de conflits d’intérêts par les membres experts et les organisations dans lesquelles ils ont un rôle-conseil.In Québec, in Canada and elsewhere in the world, expert advisory committees advise and guide government decision-makers in the choice of new drugs, vaccines to be used or interventions to be put in place. In parallel, these experts are receiving increasing support from private companies to conduct their research or to disseminate the results of their research. Such situations place them at risk of conflicts of interest and may eventually undermine confidence in public decision-making. This case study stimulates reflection into what constitutes sound and optimal management of conflict of interest situations by expert members and the organizations in which they have an advising role