First report of Desmiphora hirticollis (Olivier) (Coleoptera: Cerambycidae) on Wigandia urens (Ruiz and Pavón) H.B.K. (Hydrophilaceae) in Mexico

Desmiphora hirticollis (Olivier) (Coleoptera: Cerambycidae) was found in Oaxaca, Mexico, feeding in the stems of Wigandia urens (Ruiz and Pavón) H.B.K. (Hydrophilaceae), a new host record. Information about damage in the plant stems and some observations of the insect’s biology are provided

Cuando la ultraderecha cita a Machado. Los agujeros en la memoria democrática y el papel de la literatura

En esta contribución, se habla de literatura –de la manera en la que la literatura ha representado el pasado– y de política –en concreto, de los efectos de las deficiencias de la democracia española que hoy está en grave crisis–. Se hace desde el presente más inmediato (febrero de 2019), y por supuesto partiendo de Machado. A partir de algunas anécdotas, se muestra cómo este uso se hace desde la ignorancia más que desde la provocación, y sin encontrar siempre el rechazo de la ciudadanía que no sabe demasiado de la vida y muerte del poeta. Esa imagen, la ultraderecha usando a Machado, refleja bien el momento actual y sirve de hilo rojo a la presente reflexión. Keywords: Antonio Machado, literatura, política, ultraderecha, memoria democrática, democracia

Discussing the teaching of composition at the university

The challenge involved in the teaching of musical composition is somewhat analogous to the issue of reconciling theory and practice; this is when the teacher– student relationship triggers a flow of information that leads to the construction of new concepts that are established by either or both sides. The present paper emerged from a roundtable held at the "The Teaching of Composition at the University" colloquium, which took place at the State University of ParanaÌ in November 2019. The authors did not attempt to arrive at definitive conclusions but, rather, point out directions for critical reflection and practical approaches about the issue of teaching composition. The occasion was also an excellent one for sharing didactic experiences taking place at universities in Brazil and abroad

Análisis proteómico de la vía de señalización de CLEC-2 en plaquetas humanas mediante 2-D-DIGE y 2-DE combinado con tinción con SyproRubi: comparación de ambas aproximaciones experimentales

Comunicaciones a congreso

A 2D-DIGE-based proteomic analysis reveals differences in the platelet releasate composition when comparing thrombin and collagen stimulations

Upon stimulation, platelets release a high number of proteins (the releasate). There are clear indications that these proteins are involved in the pathogenesis of several diseases, such as atherosclerosis. In the present study we compared the platelet releasate following platelet activation with two major endogenous agonists: thrombin and collagen. Proteome analysis was based on 2D-DIGE and LC-MS/MS. Firstly, we showed the primary role of thrombin and collagen receptors in platelet secretion by these agonists; moreover, we demonstrated that GPVI is the primary responsible for collagen-induced platelet activation/aggregation. Proteomic analysis allowed the detection of 122 protein spots differentially regulated between both conditions. After excluding fibrinogen spots, down-regulated in the releasate of thrombin-activated platelets, 84 differences remained. From those, we successfully identified 42, corresponding to 37 open-reading frames. Many of the differences identified correspond to post-translational modifications, primarily, proteolysis induced by thrombin. Among others, we show vitamin K-dependent protein S, an anticoagulant plasma protein, is up-regulated in thrombin samples. Our results could have pathological implications given that platelets might be playing a differential role in various diseases and biological processes through the secretion of different subsets of granule proteins and microvesicles following a predominant activation of certain receptors.Ministerio de Economía y Competitividad (MINECO). (España)European regional developmental fund (ERDF)Ministerio de Economía y Competitividad (MINECO)/SAF2010-2251Ministerio de Economía y Competitividad (MINECO)/SAF2013-45014-

Variación del proteoma de las micropartículas plaquetarias dependiendo del estímulo: papel de las proteínas de señalización

Comunicaciones a congreso

Proteins involved in plateled activation by GPVI and ALPHAIIBBETA3 receptors are differentially regulated in acute coronary symdrome: a platelet proteomics study

Comunicaciones a congreso

High resolution 2-De-Based proteomics analysis of human atrial fibrilation

Comunicaciones a congreso