Gastropod species found in birds' nests from Argentina

Los nidos de aves son ejemplos de hábitats ocupados por un conjunto de invertebrados, como insectos, arañas, pseudoescorpiones, etc. Por primera vez se presenta una lista de gasterópodos encontrados en nidos aviarios de la Argentina. Un total de 138 especímenes pertenecientes a 11 especies, 10 géneros y 8 familias fueron hallados en 42 nidos de 6 familias de aves en 6 provincias. Sólo Pupisoma latens, representado por 58 especímenes de diferentes tamaños, fue encontrado vivo en un nido, siendo un nuevo hábitat de la especie, previamente encontrada en partes aéreas de árboles. El resto de las especies estaban representadas por animales muertos (fragmentos o conchillas vacías), que podrían estar relacionados a la dieta de las aves. Entre estas, las especies con mayor número de representantes (mayoritariamente pre-adultos) fueron Bulimulus bonariensis bonariensis y Succinea meridionalis. Los nidos de Anumbius annumbi y Furnarius rufus de la provincia de Buenos Aires tuvieron el número más elevado de ejemplares de gasterópodos. Especímenes de gasterópodos de agua dulce (Heleobia parchappii, Biomphalaria sp. y Drepanotrema sp.) constituyeron 13 % del total.Bird's nests are specialized habitats that are inhabited by a diverse suite of invertebrates, such as insects, spiders, pseudoscorpions, and ticks. This study presents a list of gastropods found in birds' nests from Argentina for the first time. A total of 138 specimens of gastropods, belonging to 11 species, 10 genera and 8 families of snails were present in the nests of 42 birds from 6 families in 6 provinces in Argentina. Fifty eight specimens of the snail Pupisoma latens of different sizes were found alive in a nest, representing a new habitat for this species, which has been previously described from the aerial parts of trees. The remaining species were represented by dead specimens (fragments or empty shells), which can be tentatively attributed to bird diets. Among these, the most abundant species were Bulimulus bonariensis bonariensis and Succinea meridionalis, both as pre-adults. The nests Anumbius annumbi and Furnarius rufus from the province of Buenos Aires had the highest number of specimens. Freshwater snails (Heleobia parchappii, Biomphalaria sp., and Drepanotrema sp.) comprised 13% of the snail species found.Fil: Miquel, Sergio Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales ; ArgentinaFil: Turienzo, Paola Noemí. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Entomología; ArgentinaFil: Di Iorio, Osvaldo Rubén. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Entomología; Argentin

Effects of Increasing Doses of Intracoronary Adenosine on the Assessment of Fractional Flow Reserve

ObjectivesThe purpose of this study was to investigate the effects of increasing dose of intracoronary adenosine on fractional flow reserve (FFR) measurement.BackgroundsFFR is a validated method for the assessment of the severity of coronary artery stenosis. It is based on the change in the pressure gradient across the stenosis after the achievement of maximal hyperemia of the coronary microcirculation that may be obtained by either intracoronary bolus or intravenous infusion of adenosine. No study has explored so far the effects of very high doses of intracoronary adenosine on FFR.MethodsFFR was assessed in 46 patients with 50 intermediate lesions during cardiac catheterization by pressure-recording guidewire (PrimeWire, Volcano, San Diego, California). FFR was calculated as the ratio of the distal coronary pressure to the aortic pressure at hyperemia. Increasing doses of adenosine were administrated (60, 120, 180, 360, and 720 μg) as intracoronary boluses. Exclusion criteria were: 1) allergy to adenosine; 2) baseline bradycardia (heart rate <50 beats/min); 3) hypotension (blood pressure <90 mm Hg); and 4) refusal to provide signed informed consent.ResultsHigh doses of intracoronary adenosine were well tolerated, with no major side effects. Increasing doses up to 720 μg progressively decreased FFR values and increased the percentage of patients showing an FFR <0.75. Among angiographic parameters, both percent stenosis and lesion length were independently associated with lower FFR values.ConclusionsThis study shows that high doses of intracoronary adenosine (up to 720 μg) increased the sensitivity of FFR in the detection of hemodynamically relevant coronary stenoses. Furthermore, lesion length and stenosis severity were independent angiographic determinants of FFR

Audiological monitoring of cisplatin exposed patients

Cisplatin is an antineoplasic drug, which has ototoxicity as a side effect. The goals of this paper were to evaluate the audiological behavior in osteosarcoma patients treated with cisplatin and to verify which evaluation method is the best for early detection of drug induced hearing loss. STUDY DESIGN: Clinical prospective. MATERIAL AND METHOD: 13 patients, that received four cisplatin cycles of 120 mg/m²/cycle divided in two days (60 mg/m²/day), were evaluated prior to start of chemotherapy, prior to each scheduled course and at the end of treatment. It was performed the pure tone audiometry (250 to 18000 Hz) and the transitory and distortion product otoacoustic emission (TOAE and DPOAE). RESULTS: In the mean values, it was observed hearing loss, after 480 mg/m² cumulative cisplatin dosage, beginning at 8 kHz. At the individual values, it was observed that 15,3% had mild to moderate hearing loss beginning at 3kHz, 15,3% beginning at 4 kHz, 15,3% beginning at 6 kHz and 15,3% beginning at 8 kHz. TOAE did not show changes before the audiometry. DPOAE showed smaller amplitude after the cycles of cisplatin, but this change happened together with the audiometry - not prior. CONCLUSION: The high frequency audiometry was more efficient to detect early ototoxicity. TOAE and DPOAE can be used as complement tests. All cisplatin exposed patients showed high frequency hearing loss, 30,6% showed hearing loss in important frequencies (3 and 4 kHz) for speech comprehension.A cisplatina é um agente quimioterápico que apresenta dentre seus efeitos colaterais a ototoxicidade. Este estudo teve como objetivos avaliar a audição de pacientes portadores de osteossarcoma expostos à cisplatina e verificar qual o método de investigação mais adequado para identificar precocemente as alterações auditivas induzidas por drogas ototóxicas. FORMA DE ESTUDO: Clínico prospectivo. MATERIAL E MÉTODO: 13 indivíduos portadores de osteossarcoma que receberam quatro ciclos de cisplatina de 120 mg/m²/ciclo, fracionados em dois dias de aplicação (60 mg/m²/dia), foram submetidos à avaliação audiológica - audiometria tonal liminar (250 a 18000 Hz) e emissões otoacústicas transitórias (EOAT) e por produto de distorção (EOAPD) - antes do início do tratamento e após cada ciclo de cisplatina. RESULTADOS: Observou-se, nos valores médios, perda auditiva após a dose cumulativa de 480 mg/m² a partir de 8 kHz. Quanto aos valores individuais, 15,3% dos pacientes apresentaram perda auditiva de grau leve a moderado a partir de 3 kHz, 15,3% a partir de 4 kHz, 15,3% a partir de 6 kHz e 15,3% a partir de 8 kHz. Não foi observada redução na amplitude das EOAT precocemente à alteração dos limiares nas altas freqüências. Houve redução da amplitude das EOAPD concomitante ao aumento do limiar de audibilidade. CONCLUSÃO: A audiometria de altas freqüências é mais efetiva na detecção precoce da perda auditiva induzida por cisplatina. As EOAT e EOAPD podem ser usadas como complemento à avaliação audiométrica. Todos os pacientes expostos à cisplatina têm perda auditiva nas altas freqüências, e destes, 30,6% tem perda auditiva a partir das freqüências de 3 e 4 kHz consideradas importantes para a compreensão da fala.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Otorrinolaringologia e Distúrbios da Comunicação HumanaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de PediatriaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Instituto de Oncologia PediátricaUNIFESP, EPM, Depto. de Otorrinolaringologia e Distúrbios da Comunicação HumanaUNIFESP, EPM, Depto. de PediatriaUNIFESP, EPM, Instituto de Oncologia PediátricaSciEL

Dental pulp stem cells bioadhesivity: evaluation on mineral-trioxide-aggregate.

Stem cells are undifferentiated cells that have the capacity to self-renew. They have been discovered in many adult tissues, including teeth. Dental Pulp Mesenchymal Stem Cells (DP-MSCs) are involved in dental repair by activation of growth factors, released after caries and have the ability to regenerate a dentin-pulp-like complex. The molecular/cellular research gives the possibility to grow new tissues and biological structures for clinical applications, providing cells for therapies including cell transplantation and tissue engineering. In this study DP-MSCs were derived from dental pulp of 10 donors. To evaluate material toxicity, after in vitro isolation, the cells were seeded on mineral trioxide aggregate (MTA). Initial light microscopy investigation of cells revealed no signs of cell death due to toxicity or infection, on the contrary the scaffolds supplied an excellent support for cell structures, the cells proliferated and adhered to substrate. Similar observation was seen in scanning electron microscopy, in particular the cells had proliferated and spread, covering a considerable part of the surface of the biomaterials investigated, with an elaborate form of attachment, in fact, the cells formed a continuous layer on the upper surface of the MTA. In conclusion, the aim of this study is to demonstrate that DP-MSCs combined with MTA could be a potential source for regenerative medicine, encouraging further study to evaluate the new-dentin formation

Risk of recurrence after a first episode of symptomatic venous thromboembolism provoked by a transient risk factor: a systematic review.

We aimed to determine the risk of recurrence for symptomatic venous thromboembolism (VTE) provoked by different transient risk factors. DATA SOURCES: MEDLINE, EMBASE, and Cochrane Collaboration Registry of Randomized Trials databases were searched. STUDY SELECTION: Prospective cohort studies and randomized trials of patients with a first episode of symptomatic VTE provoked by a transient risk factor and treated for at least 3 months were identified. DATA EXTRACTION: Number of patients and recurrent VTE during the 0- to 12-month and 0- to 24-month intervals after stopping therapy, study design, and provoking risk factor characteristics were extracted. DATA SYNTHESIS: Annualized recurrence rates were calculated and pooled across studies. At 24 months, the rate of recurrence was 3.3% per patient-year (11 studies, 2268 patients) for all patients with a transient risk factor, 0.7% per patient-year (3 studies, 248 patients) in the subgroup with a surgical factor, and 4.2% per patient-year (3 studies, 509 patients) in the subgroup with a nonsurgical factor. In the same studies, the rate of recurrence after unprovoked VTE was 7.4% per patient-year. The rate ratio for a nonsurgical compared with a surgical factor was 3.0 and for unprovoked thrombosis compared with a nonsurgical factor was 1.8 at 24 months. CONCLUSIONS: The risk of recurrence is low if VTE is provoked by surgery, intermediate if provoked by a nonsurgical risk factor, and high if unprovoked. These risks affect whether patients with VTE should undergo short-term vs indefinite treatment

Relationships derived from relationships: Competition between arbitrary relationships and physical similarity

El estudio de las relaciones de similitud física (RSF) y las relaciones arbitrarias resulta de interés ya que permite evaluar la capacidad de formación y discriminación de nuevas relaciones entre estímulos cuando está disponible un criterio de respuesta potencialmente más arraigado, como el de similitud física. El propósito del presente estudio fue investigar los efectos de la competencia de respuesta entre las relaciones derivadas de relaciones (RDR) y las RSF. Se consideraron como indicadores de respuesta el número de respuestas por las RDR y los tiempos de respuesta. Participaron del estudio 158 sujetos adultos. Los resultados demostraron que, cuando los participantes formaron RDR consistentemente, la presencia de competencia no generó dificultad para seleccionar respuestas por RDR. Los participantes que respondieron inconsistentemente a las RDR, sí presentaron efectos de competencia en ambos indicadores de respuesta. Se pone de manifiesto la conveniencia de utilizar los tiempos de respuesta además de la cantidad de respuestas por la RDR, como una medida más fina del control de estímulos y de estudiar tanto el desempeño de los participantes que responden consistentemente a todas las relaciones derivadas como el de aquellos que sólo exhiben consistencia en el establecimiento de clases de equivalencia de estímulos. Debe atenderse tanto a las relaciones que son estrictamente arbitrarias, como también a las RSF en tanto se sabe que la tendencia a considerar estas relaciones estaría también en la base del formación del razonamiento analógico.The study of physical similarity relationships (PSR) and arbitrary relationships is of interest because it allows the assessment of the ability to form and discriminate new relationships between stimuli when another response criterion more established is potentially available, like that of physical similarity. The importance of this type of relational responding is that this behavior is similar to that of analogical reasoning and its study has the advantage of allowing systematic control of familiarity and stimulus learning. The relationships derived from relationships (RDR) imply the ability to establish relationships based not on the stimulus, but on the relations established between combinations of stimuli. In this sense, it is necessary to address both the relationships that are strictly arbitrary as well as PSR, as it is known that the tendency to consider these relationships would also be the basis for the formation of analogical reasoning. The purpose of this study was to investigate the effects of response competition between the RDR and the PSR. The number of responses by the RDR and response times were considered as indicators of response. The study included 158 adult subjects. The results showed that when participants formed RDR consistently, the presence of competition did not cause difficulties in selecting responses by RDR. By contrast, participants who responded inconsistently to the RDR did show effects of competition in both indicators of response. The advantage of using the response times in addition to the number of responses by the RDR is shown as a finer measure of stimulus control. In turn, a special emphasis is made on the importance of studying both the performance of the participants who responded consistently to all derived relations as well as those that only exhibit consistency in establishing stimulus equivalence classes.Fil: Fiorentini, Leticia. Universidad de Buenos Aires. Facultad de Psicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Arismendi, Mariana. Universidad de Buenos Aires. Facultad de Psicología; ArgentinaFil: Vernis, Sergio. Universidad de Buenos Aires. Facultad de Psicología; ArgentinaFil: Primero, Gerardo. Universidad de Buenos Aires. Facultad de Psicología; ArgentinaFil: Sánchez, Federico José. Universidad de Buenos Aires. Facultad de Psicología; ArgentinaFil: Tabullo, Angel Javier. Universidad de Buenos Aires. Facultad de Psicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Iorio, Alberto Andres. Universidad de Buenos Aires. Facultad de Psicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentin

Spontaneous rupture of the renal pelvis due to squamous cell carcinoma of the urinary bladder: a rare case

Bladder cancer is the fourth most common tumor in men and is usually diagnosed around the seventh decade of life. The predominant histological type is transitional cell carcinoma, while squamous cell carcinomas and adenocarcinomas are less common. Spontaneous rupture of the excretory system, an obstructive complication, is a rare occurrence and even more uncommon when caused by neoplasia. The aim of this article is to report the case of a male patient with spontaneous rupture of the pelvis due to squamous cell carcinoma of the bladder. With regard to renal pelvis rupture due to primary urinary tract obstruction, stone formation (lithiasis) is the most common cause, accounting for 50%, while neoplasia ranks fifth. As for the histological subtypes of the neoplasm, it is essential to note that transitional cell carcinoma is observed in 90% of cases

Stimulus equivalence relations and equivalence-equivalence relations: effects of the training structure

En el presente estudio se investiga la influencia de la estructura de entrenamiento en la formación de relaciones de equivalencia y de “equivalencia-equivalencia”. Se estudiaron tres grupos de sujetos los cuales fueron entrenados con las estructuras: Muchos a Uno, Uno a Muchos o Serie Lineal para las relaciones condicionales. Se verificó el efecto de estructura de entrenamiento sobre la variable porcentaje de aciertos en el test de relaciones de equivalencia. Sin embargo, este fenómeno no se replicó en el test de relaciones de equivalencia-equivalencia. Los resultados indican que la estructura de entrenamiento influye cuando se forman relaciones de equivalencia, pero no cuando se forman relaciones de equivalencia-equivalencia. Se analizan los hallazgos considerando los requisitos para la formación de relaciones de equivalencia-equivalencia.The influence of training structure on the formation of equivalence relations and equivalence-equivalence relations was assessed. Three groups learned conditional relations using different training structures: Many to One, One to Many and Linear Series. The results showed a training structure effect on the percentage of correct responses in the equivalence relations test. However, this effect was not observed on the test of equivalence-equivalence relations. These results show that training structure has effects on the formation of equivalence relations, but it has no influence on equivalence-equivalence relations. These findings are analyzed according to the requirements for the formation of equivalence-equivalence relations.Fil: Fiorentini, Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Vernis, Sergio. Universidad de Buenos Aires. Facultad de Psicologia; ArgentinaFil: Arismendi, Mariana. Universidad de Buenos Aires. Facultad de Psicologia; ArgentinaFil: Primero, Gerardo. Universidad de Buenos Aires. Facultad de Psicologia; ArgentinaFil: Argibay, Juan Carlos. Universidad de Buenos Aires. Facultad de Psicologia; ArgentinaFil: Sanchez, Federico. Universidad de Buenos Aires. Facultad de Psicologia; ArgentinaFil: Tabullo, Angel Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Segura, Enrique Teodoro. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Iorio, Alberto Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentin

Impact of DEL22q11, trisomy 21, and other genetic syndromes on surgical outcome of conotruncal heart defects

ObjectiveGenetic syndromes occur in more than 20% of patients with conotruncal heart defects. We investigated the impact of genetic syndromes on the surgical outcome of conotruncal anomalies in infancy.MethodsThis retrospective study reviews the outcome of 787 patients (median age 6.3 months) who underwent primary (598) or staged (189) repair of a conotruncal defect between 1992 and 2007.ResultsProven genetic syndrome was diagnosed in 211 patients (26.8%), including del22q11 (91 patients), trisomy 21 (29 patients), VACTERL (18 patients), and other syndromes (73 patients). Primary repair was accomplished in 80.9% of nonsyndromic patients and 74.4% of syndromic patients (P = .18) Fifteen-year cumulative survival was 84.3% ± 2.3% in nonsyndromic patients and 73.2% ± 4.2% in syndromic patients (P < .001). Primary and staged repair allowed similar 15-year survival (81.4% ± 4.5% vs 79.1% ± 5.1%, P = .8). Freedom from noncardiac cause of death was significantly lower in syndromic patients (P = .0056). Fifteen-year Kaplan–Meier survival was 87.6% ± 3.9% for del22q11, 95.8% ± 4.1% for trisomy 21, 56.8% ± 6.3% for VACTERL, and 62.3% ± 12.7% for patients with other syndromes (P = .022). Total intensive care unit stay was 10.8 ± 4.9 days in syndromic patients and 5.1 ± 1.7 days in nonsyndromic patients (P < .001). Freedom from reintervention 15 years after repair was 79.6% ± 4.9% in nonsyndromic patients and 62.4% ± 7.4% in syndromic patients (P = .007).ConclusionDel22q11 and trisomy 21 do not represent risk factors for mortality after repair of conotruncal anomalies, whereas other syndromes adversely affect the surgical outcome for predominant noncardiac attrition. Higher morbidity and lower mid-term freedom from reintervention can be predicted in syndromic patients

Los jóvenes y la transmisión de la experiencia argentina reciente

Este libro pretende expresar parte del trabajo realizado durante Seminario "Entre el pasado y el futuro. Los jóvenes y la transmisión de la experiencia argentina reciente" en el que participaron Institutos de Formación Docente de distintos lugares del país, ante la convocatoria realizada por el proyecto "A 30 años del golpe"Este libro está dividido en cuatro grandes secciones. Con la señalada intención de reproducir lo más fielmente posible la propia estructura del Seminario, las tres primeras secciones reproducen las actividades de cada una de las tres jornadas en que funcionó el Seminario