Super FSR tunable optical microbubble resonator

An optical resonator is often called fully tunable if its tunable range exceeds the spectral interval that contains the resonances at all the characteristic modes of this resonator. For the high Q-factor spheroidal and toroidal microresonators, this interval coincides with the azimuthal free spectral range. In this Letter, we demonstrate the first mechanically fully tunable spheroidal microresonator created of a silica microbubble having a 100 micron order radius and a micron order wall thickness. The tunable bandwidth of this resonator is more than two times greater than its azimuthal free spectral range

Urinary Protein Profiles in a Rat Model for Diabetic Complications

Diabetes mellitus is estimated to affect ∼24 million people in the United States and more than 150 million people worldwide. There are numerous end organ complications of diabetes, the onset of which can be delayed by early diagnosis and treatment. Although assays for diabetes are well founded, tests for its complications lack sufficient specificity and sensitivity to adequately guide these treatment options. In our study, we employed a streptozotocin- induced rat model of diabetes to determine changes in urinary protein profiles that occur during the initial response to the attendant hyperglycemia (e.g. the first two months) with the goal of developing a reliable and reproducible method of analyzing multiple urine samples as well as providing clues to early markers of disease progression. After filtration and buffer exchange, urinary proteins were digested with a specific protease, and the relative amounts of several thousand peptides were compared across rat urine samples representing various times after administration of drug or sham control. Extensive data analysis, including imputation of missing values and normalization of all data was followed by ANOVA analysis to discover peptides that were significantly changing as a function of time, treatment and interaction of the two variables. The data demonstrated significant differences in protein abundance in urine before observable pathophysiological changes occur in this animal model and as function of the measured variables. These included decreases in relative abundance of major urinary protein precursor and increases in pro-alpha collagen, the expression of which is known to be regulated by circulating levels of insulin and/or glucose. Peptides from these proteins represent potential biomarkers, which can be used to stage urogenital complications from diabetes. The expression changes of a pro-alpha 1 collagen peptide was also confirmed via selected reaction monitoring

Митний контроль та митне оформлення продуктів морського та річкового промислу українського походження

Ільченко К. Р. Митний контроль та митне оформлення продуктів морського та річкового промислу українського походження / К. Р. Ільченко // Правові та інституційні механізми забезпечення розвитку держави та права в умовах євроінтеграції : матеріали Міжнародної науково-практичної конференції (20 травня 2016 р., м. Одеса) : у 2 т. Т. 1 / відп. ред. М. В. Афанасьєва. - Одеса : Юридична література, 2016. - С. 439-441

Temperature measurement and stabilization in a birefringent whispering gallery resonator

Temperature measurement with nano-Kelvin resolution is demonstrated at room temperature, based on the thermal dependence of an optical crystal anisotropy in a high quality whispering gallery resonator. As the resonator's TE and TM modes frequencies have different temperature coefficients, their differential shift provides a sensitive measurement of the temperature variation, which is used for active stabilization of the temperature

Chaotic Waveguide-Based Resonators for Microlasers

We propose the construction of highly directional emission microlasers using two-dimensional high-index semiconductor waveguides as {\it open} resonators. The prototype waveguide is formed by two collinear leads connected to a cavity of certain shape. The proposed lasing mechanism requires that the shape of the cavity yield mixed chaotic ray dynamics so as to have the appropiate (phase space) resonance islands. These islands allow, via Heisenberg's uncertainty principle, the appearance of quasi bound states (QBS) which, in turn, propitiate the lasing mechanism. The energy values of the QBS are found through the solution of the Helmholtz equation. We use classical ray dynamics to predict the direction and intensity of the lasing produced by such open resonators for typical values of the index of refraction.Comment: 5 pages, 5 figure

Practical Investigations of the Method for Indirect Control of Acoustic Load Parameters

Abstract Article is devoted approbation of a method of indirect control of parameters of acoustic loading. Results of measurement of parameters of acoustic loading are presented

Heterogeneously integrated microdisk lasers for optical interconnects and optical logic

Optical interconnect and optical packet switching systems could take advantage of small footprint, low power lasers and optical logic elements. Microdisk lasers, with a diameter below 10 mu m and fabricated in InP membranes with a high index contrast, offer this possibility at the telecom wavelengths. The lasers are fabricated using heterogeneous integration of InP membranes on silicon-on-insulator (SOI) passive waveguide circuits, which allows to combine the active elements with compact, high-index contrast passive elements. The lasing mode in such microdisk lasers is a whispering gallery mode, which can be either in the clockwise (CW) or counter clockwise direction (CCW) or in both. The coupling to the SOI wire waveguides is through evanescent coupling. Predefined, unidirectional operation can be achieved by terminating the SOI wires at one end with Bragg gratings. For all-optical flip-flops, the laser operation must be switchable between CW and CCW, using short optical pulses. Unidirectional operation in either direction is only possible if the coupling between CW and CCW direction is very small, requiring small sidewall surface roughness, and if the gain suppression is sufficiently large, requiring large internal power levels. All-optical flip-flops based on microdisk lasers with diameter of 7.5 mu m have been demonstrated. They operate with a CW power consumption of a few mW and switch in 60ps with switching energies as low as 1.8fJ. Operation as all-optical gate has also been demonstrated. The surface roughness is limited through optimized etching of the disks and the large internal power is obtained through good heat sink