63 research outputs found
Multiband superconductivity with unexpected deficiency of nodal quasiparticles in CeCu2Si2
Superconductivity in the heavy-fermion compound CeCu2Si2 is a prototypical
example of Cooper pairs formed by strongly correlated electrons. For more than
30 years, it has been believed to arise from nodal d-wave pairing mediated by a
magnetic glue. Here, we report a detailed study of the specific heat and
magnetization at low temperatures for a high-quality single crystal.
Unexpectedly, the specific-heat measurements exhibit exponential decay with a
two-gap feature in its temperature dependence, along with a linear dependence
as a function of magnetic field and the absence of oscillations in the field
angle, reminiscent of multiband full-gap superconductivity. In addition, we
find anomalous behavior at high fields, attributed to a strong Pauli
paramagnetic effect. A low quasiparticle density of states at low energies with
a multiband Fermi-surface topology would open a new door into electron pairing
in CeCu2Si2.Comment: 5 pages, 4 figures (main text) + 5 pages, 6 figures (supplemental
material), published in Phys. Rev. Let
Thermodynamic study of gap structure and pair-breaking effect by magnetic field in the heavy-fermion superconductor CeCu2Si2
This paper presents the results of specific-heat and magnetization
measurements, in particular their field-orientation dependence, on the first
discovered heavy-fermion superconductor CeCuSi (
K). We discuss the superconducting gap structure and the origin of the
anomalous pair-breaking phenomena, leading e.g., to the suppression of the
upper critical field , found in the high-field region. The data
show that the anomalous pair breaking becomes prominent below about 0.15 K in
any field direction, but occurs closer to for . The
presence of this anomaly is confirmed by the fact that the specific-heat and
magnetization data satisfy standard thermodynamic relations. Concerning the gap
structure, field-angle dependences of the low-temperature specific heat within
the and planes do not show any evidence for gap nodes. From
microscopic calculations in the framework of a two-band full-gap model, the
power-law-like temperature dependences of and , reminiscent of nodal
superconductivity, have been reproduced reasonably. These facts further support
multiband full-gap superconductivity in CeCuSi.Comment: 10 pages, 8 figures, published in Phys. Rev.
Comparison of conservative treatment versus transcatheter arterial embolisation for the treatment of spontaneously ruptured hepatocellular carcinoma
Purpose: To elucidate the prognostic factors in the spontaneous rupture of hepatocellular carcinoma (HCC) and to determine whether transcatheter arterial embolisation (TAE) is associated with better prognosis compared to conservative treatment. Material and methods: A retrospective multicentre study was conducted involving 71 patients with spontaneous rupture of HCC. A conservative treatment group (Cons T group) included 20 patients, while a transcatheter arterial embolisation group (TAE group) included 51 patients. Results: The median survival time (MST) in the Cons T group was only 16 days and the survival rate was 39% at one month, whereas the MST in the TAE group was 28 days and the one month survival rate was 63%. However, there is no statistically significant difference in the overall survival between Cons T and TAE groups (p = 0.213). Multivariable analysis identified only the presence of distant metastasis as an independent prognostic factor (p = 0.023). A subanalysis including patients without distant metastasis showed that the presence of portal vein tumour thrombosis was a significant prognostic factor (p = 0.015). Conclusions: Distant metastasis appears to be a prognostic factor in spontaneous rupture of HCC. In cases without distant metastasis, portal vein tumour thrombosis could influence the prognosis. Our data failed to prove any benefit of TAE as the primary management
Experimental renal and hepatic artery embolization with a new embolic agent, atelocollagen, in a porcine model
PURPOSEWe aimed to investigate the potentiality of atelocollagen, a new embolic agent which is collagen type I in a porcine experimental model. MATERIALS AND METHODSThree pigs underwent transcatheter embolization of lower interlobular arteries of the renal artery (n=6) and one branch of the hepatic artery (n=3) with collagen type I. Angiography was performed prearterial, during, and postarterial embolization. After the procedure, samples from the embolized organs were evaluated by histological analysis. RESULTSSix lower interlobular renal arteries and three hepatic arteries were successfully embolized by administration of 0.8±0.3 mL and 2.9±1.2 mL, respectively, of the collagen type I. Histological findings of the embolized kidney specimens showed that the collagenous materials filled the arterial lumen, whose size ranged from 2.02 to 839.82 μm and reached the level of afferent arteries of glomerular tufts. Although the area of occluded arteries of the liver was smaller than the kidney, histological findings of the liver specimens showed that the collagenous materials filled small arterial lumens from 2.81 to 187.86 μm in diameter. CONCLUSIONAtelocollagen, a collagen type I, has the potential to be used to embolize the distal vessels of both renal and hepatic arteries
Real-world outcome of rTMS treatment for depression within the Japanese public health insurance system: Registry data from Kansai TMS network
Imazu S., Ikeda S., Toi Y., et al. Real-world outcome of rTMS treatment for depression within the Japanese public health insurance system: Registry data from Kansai TMS network. Asian Journal of Psychiatry 97, 104082 (2024); https://doi.org/10.1016/j.ajp.2024.104082.This study registered consecutive cases to elucidate the efficacy of rTMS treatment for depression within the Japanese public health insurance system. Of the 102 patients with depression who received rTMS over the left dorsolateral prefrontal cortex, 44 (43.1 %) patients reached remission and 14 (13.7 %) patients did not reach remission but responded to treatment. No serious adverse events occurred. Low baseline HAMD-17 score was associated with remission after rTMS treatment. Favorable outcomes of rTMS treatment were shown in this cohort within the Japanese public insurance system. Our results provide insights into rTMS treatment for depression in real-world clinical setting
Functional localization and effective connectivity of cortical theta and alpha oscillatory activity during an attention task
Objectives: The aim of this paper is to investigate cortical electric neuronal activity as an indicator of brain function, in a mental arithmetic task that requires sustained attention, as compared to the resting state condition. The two questions of interest are the cortical localization of different oscillatory activities, and the directional effective flow of oscillatory activity between regions of interest, in the task condition compared to resting state. In particular, theta and alpha activity are of interest here, due to their important role in attention processing.
Methods: We adapted mental arithmetic as an attention ask in this study. Eyes closed 61-channel EEG was recorded in 14 participants during resting and in a mental arithmetic task (“serial sevens subtraction”). Functional localization and connectivity analyses were based on cortical signals of electric neuronal activity estimated with sLORETA (standardized low resolution electromagnetic tomography). Functional localization was based on the comparison of the cortical distributions of the generators of oscillatory activity between task and resting conditions. Assessment of effective connectivity was based on the iCoh (isolated effective coherence) method, which provides an appropriate frequency decomposition of the directional flow of oscillatory activity between brain regions. Nine regions of interest comprising nodes from the dorsal and ventral attention networks were selected for the connectivity analysis.
Results: Cortical spectral density distribution comparing task minus rest showed significant activity increase in medial prefrontal areas and decreased activity in left parietal lobe for the theta band, and decreased activity in parietal-occipital regions for the alpha1 band. At a global level, connections among right hemispheric nodes were predominantly decreased during the task condition, while connections among left hemispheric nodes were predominantly increased. At more detailed level, decreased flow from right inferior frontal gyrus to anterior cingulate cortex for theta, and low and high alpha oscillations, and increased feedback (bidirectional flow) between left superior temporal gyrus and left inferior frontal gyrus, were observed during the arithmetic task.
Conclusions: Task related medial prefrontal increase in theta oscillations possibly corresponds to frontal midline theta, while parietal decreased alpha1 activity indicates the active role of this region in the numerical task. Task related decrease of intracortical right hemispheric connectivity support the notion that these nodes need to disengage from one another in order to not interfere with the ongoing numerical processing. The bidirectional feedback between left frontal-temporal-parietal regions in the arithmetic task is very likely to be related to attention network working memory function.
Significance: The methods of analysis and the results presented here will hopefully contribute to clarify the roles of the different EEG oscillations during sustained attention, both in terms of their functional localization and in terms of how they integrate brain function by supporting information flow between different cortical regions. The methodology presented here might be clinically relevant in evaluating abnormal attention function
Noninvasive prediction of shunt operation outcome in idiopathic normal pressure hydrocephalus
Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome characterized by gait disturbance, cognitive deterioration and urinary incontinence in elderly individuals. These symptoms can be improved by shunt operation in some but not all patients. Therefore, discovering predictive factors for the surgical outcome is of great clinical importance. We used normalized power variance (NPV) of electroencephalography (EEG) waves, a sensitive measure of the instability of cortical electrical activity, and found significantly higher NPV in beta frequency band at the right fronto-temporo-occipital electrodes (Fp2, T4 and O2) in shunt responders compared to non-responders. By utilizing these differences, we were able to correctly identify responders and non-responders to shunt operation with a positive predictive value of 80% and a negative predictive value of 88%. Our findings indicate that NPV can be useful in noninvasively predicting the clinical outcome of shunt operation in patients with iNPH
Fully gapped superconductivity with no sign change in the prototypical heavy-fermion CeCu2Si2
In exotic superconductors including high- copper-oxides, the
interactions mediating electron Cooper-pairing are widely considered to have a
magnetic rather than the conventional electron-phonon origin. Interest in such
exotic pairing was initiated by the 1979 discovery of heavy-fermion
superconductivity in CeCuSi, which exhibits strong antiferromagnetic
fluctuations. A hallmark of unconventional pairing by anisotropic repulsive
interactions is that the superconducting energy gap changes sign as a function
of the electron momentum, often leading to nodes where the gap goes to zero.
Here, we report low-temperature specific heat, thermal conductivity and
magnetic penetration depth measurements in CeCuSi, demonstrating the
absence of gap nodes at any point on the Fermi surface. Moreover,
electron-irradiation experiments reveal that the superconductivity survives
even when the electron mean free path becomes substantially shorter than the
superconducting coherence length. This indicates that superconductivity is
robust against impurities, implying that there is no sign change in the gap
function. These results show that, contrary to long-standing belief, heavy
electrons with extremely strong Coulomb repulsions can condense into a
fully-gapped s-wave superconducting state, which has an on-site attractive
pairing interaction.Comment: 8 pages, 5 figures + Supplement (3 pages, 5 figures
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