Advancing research on climate change, conflict and migration

Policy makers across the entire globe have repetitively expressed concern about climate change as a trigger of mass migration and increased political instability. Recent research on both climate-conflict and climatemigrationlinkages has gained significant attention in the scientific and public debate. Both research fields are deeply intertwined and share some common characteristics. They also have been rapidly evolving during the past years with major achievements being made. Perhaps most importantly, an improved understanding of the role of (potential) climate change impacts in migration and conflicts has been achieved, which has been essential for moving beyond environmental determinism toward a more nuanced exploration of the  interlinkages between climate, conflict and migration. Yet, significant conversations and uncertainties continue to exist, hence indicating the urgent need for further advances in these fields. Here, we debate cross-cutting andcommon pitfalls in both research fields and their implications for policy and research. These pitfalls include (i) insufficient attention to context factors and causal chains, (ii) underestimation of complex spatio-temporal patterns, (iii) discrepancies between quantitative and qualitative evidence, (iv) the non-consideration of adaptation strategies, and (v) a narrow spectrum of methods. We illustrate best practices and suggest ways to move the debate forward

Gender in the Climate-Conflict Nexus: "Forgotten" Variables, Alternative Securities, and Hidden Power Dimensions

The literature on the security implications of climate change, and in particular on potential climate-conflict linkages, is burgeoning. Up until now, gender considerations have only played a marginal role in this research area. This is despite growing awareness of intersections between protecting women’s rights, building peace and security, and addressing environmental changes. This article advances the claim that adopting a gender perspective is integral for understanding the conflict implications of climate change. We substantiate this claim via three main points. First, gender is an essential, yet insufficiently considered intervening variable between climate change and conflict. Gender roles and identities as well as gendered power structures are important in facilitating or preventing climate-related conflicts. Second, climate change does affect armed conflicts and social unrest, but a gender perspective alters and expands the notion of what conflict can look like, and whose security is at stake. Such a perspective supports research inquiries that are grounded in everyday risks and that document alternative experiences of insecurity. Third, gender-differentiated vulnerabilities to both climate change and conflict stem from inequities within local power structures and socio-cultural norms and practices, including those related to social reproductive labor. Recognition of these power dynamics is key to understanding and promoting resilience to conflict and climate change. The overall lessons drawn for these three arguments is that gender concerns need to move center stage in future research and policy on climate change and conflicts

The critical geopolitics of water conflicts in school textbooks: The case of Germany

A considerable body of critical literature has analysed how scientific discussions on water-conflict links are picked up in the political, academic, economic, civil society and media domains. By contrast, there are almost no such studies for the domain of education. This void is crucial as school attendance rates and the prevalence of environmental education are on the rise, while school education has privileged access to young people during their political socialisation. We address this void by analysing the depiction of water conflicts in school textbooks from a critical geopolitics perspective. More specifically, we use a combination of quantitative and qualitative methods to analyse the visual and textual content of German geography textbooks published between 2000 and 2017. Our findings reveal that the analysed school textbooks securitise water and overstate the risk of water conflicts, which could yield a range of negative societal effects. The textbooks further reproduce Orientalist stereotypes about the Global South, and about the Middle East in particular, and often promote an uncritical green economy stance towards the privatisation of water. Water conflicts are hence discussed in the context of a crisis discourse and reproduce powerful knowledge that privileges certain political interests at the expense of others

The Future of Environmental Peace and Conflict Research

Interest in the intersections of environmental issues, peace and conflict has surged in recent years. Research on the topic has developed along separate research streams, which broadened the knowledge base considerably, but hardly interact across disciplinary, methodological, epistemological and ontological silos. Our forum addresses this gap by bringing into conversation six research streams on the environment, peace and conflict: environmental change and human security, climate change and armed conflict, environmental peacebuilding, political ecology, securitisation of the environment, and decolonizing environmental security. For each research stream, we outline core findings, potentials for mutual enrichment with other streams, and prospects for future research

Benzodiazepine use and risk of dementia: prospective population based study

Producción CientíficaObjective To evaluate the association between use of benzodiazepines and incident dementia. Design Prospective, population based study. Setting PAQUID study, France. Participants 1063 men and women (mean age 78.2 years) who were free of dementia and did not start taking benzodiazepines until at least the third year of follow-up. Main outcome measures Incident dementia, confirmed by a neurologist. Results During a 15 year follow-up, 253 incident cases of dementia were confirmed. New use of benzodiazepines was associated with an increased risk of dementia (multivariable adjusted hazard ratio 1.60, 95% confidence interval 1.08 to 2.38). Sensitivity analysis considering the existence of depressive symptoms showed a similar association (hazard ratio 1.62, 1.08 to 2.43). A secondary analysis pooled cohorts of participants who started benzodiazepines during follow-up and evaluated the association with incident dementia. The pooled hazard ratio across the five cohorts of new benzodiazepine users was 1.46 (1.10 to 1.94). Results of a complementary nested case-control study showed that ever use of benzodiazepines was associated with an approximately 50% increase in the risk of dementia (adjusted odds ratio 1.55, 1.24 to 1.95) compared with never users. The results were similar in past users (odds ratio 1.56, 1.23 to 1.98) and recent users (1.48, 0.83 to 2.63) but reached significance only for past users. Conclusions In this prospective population based study, new use of benzodiazepines was associated with increased risk of dementia. The result was robust in pooled analyses across cohorts of new users of benzodiazepines throughout the study and in a complementary case-control study. Considering the extent to which benzodiazepines are prescribed and the number of potential adverse effects of this drugclass in the general population, indiscriminate widespread use should be cautioned against

Differentiation of human adipose-derived stem cells into neuron/motoneuron-like cells for cell replacement therapy of spinal cord injury

Human adipose-derived stem cells (hADSCs) are increasingly presumed to be a prospective stem cell source for cell replacement therapy in various degenerative and/or traumatic diseases. The potential of trans-differentiating hADSCs into motor neuron cells indisputably provides an alternative way for spinal cord injury (SCI) treatment. In the present study, a stepwise and efficient hADSC trans-differentiation protocol with retinoic acid (RA), sonic hedgehog (SHH), and neurotrophic factors were developed. With this protocol hADSCs could be converted into electrophysiologically active motoneuron-like cells (hADSC-MNs), which expressed both a cohort of pan neuronal markers and motor neuron specific markers. Moreover, after being primed for neuronal differentiation with RA/SHH, hADSCs were transplanted into SCI mouse model and they survived, migrated, and integrated into injured site and led to partial functional recovery of SCI mice. When ablating the transplanted hADSC-MNs harboring HSV-TK-mCherry overexpression system with antivirial Ganciclovir (GCV), functional relapse was detected by motor-evoked potential (MEP) and BMS assays, implying that transplanted hADSC-MNs participated in rebuilding the neural circuits, which was further confirmed by retrograde neuronal tracing system (WGA). GFP-labeled hADSC-MNs were subjected to whole-cell patch-clamp recording in acute spinal cord slice preparation and both action potentials and synaptic activities were recorded, which further confirmed that those pre-conditioned hADSCs indeed became functionally active neurons in vivo. As well, transplanted hADSC-MNs largely prevented the formation of injury-induced cavities and exerted obvious immune-suppression effect as revealed by preventing astrocyte reactivation and favoring the secretion of a spectrum of anti-inflammatory cytokines and chemokines. Our work suggests that hADSCs can be readily transformed into MNs in vitro, and stay viable in spinal cord of the SCI mouse and exert multi-therapeutic effects by rebuilding the broken circuitry and optimizing the microenvironment through immunosuppression

Research and Design of a Routing Protocol in Large-Scale Wireless Sensor Networks

无线传感器网络，作为全球未来十大技术之一，集成了传感器技术、嵌入式计算技术、分布式信息处理和自组织网技术，可实时感知、采集、处理、传输网络分布区域内的各种信息数据，在军事国防、生物医疗、环境监测、抢险救灾、防恐反恐、危险区域远程控制等领域具有十分广阔的应用前景。 本文研究分析了无线传感器网络的已有路由协议，并针对大规模的无线传感器网络设计了一种树状路由协议，它根据节点地址信息来形成路由，从而简化了复杂繁冗的路由表查找和维护，节省了不必要的开销，提高了路由效率，实现了快速有效的数据传输。 为支持此路由协议本文提出了一种自适应动态地址分配算——ADAR（AdaptiveDynamicAddre...As one of the ten high technologies in the future, wireless sensor network, which is the integration of micro-sensors, embedded computing, modern network and Ad Hoc technologies, can apperceive, collect, process and transmit various information data within the region. It can be used in military defense, biomedical, environmental monitoring, disaster relief, counter-terrorism, remote control of haz...学位：工学硕士院系专业：信息科学与技术学院通信工程系_通信与信息系统学号：2332007115216