287 research outputs found
The Discovery of a Very Narrow-Line Star Forming Obat a Redshift of 5.66ject
We report on the discovery of a very narrow-line star forming object beyond
redshift of 5. Using the prime-focus camera, Suprime-Cam, on the 8.2 m Subaru
telescope together with a narrow-passband filter centered at
= 8150 \AA with passband of = 120 \AA, we have obtained a very
deep image of the field surrounding the quasar SDSSp J104433.04012502.2 at a
redshift of 5.74. Comparing this image with optical broad-band images, we have
found an object with a very strong emission line. Our follow-up optical
spectroscopy has revealed that this source is at a redshift of
, forming stars at a rate
yr. Remarkably, the velocity dispersion of Ly-emitting gas is
only 22 km s. Since a blue half of the Ly emission could be
absorbed by neutral hydrogen gas, perhaps in the system, a modest estimate of
the velocity dispersion may be 44 km s. Together with a linear
size of 7.7 kpc, we estimate a lower limit of the dynamical mass
of this object to be . It is thus suggested that
LAE J10440123 is a star-forming dwarf galaxy (i.e., a subgalactic object or
a building block) beyond redshift 5 although we cannot exclude a possibility
that most Ly emission is absorbed by the red damping wing of neutral
intergalactic matter.Comment: 6 pages, 2 figures. ApJ Letters, in pres
Broken rotational symmetry in the pseudogap phase of a high-Tc superconductor
The nature of the pseudogap phase is a central problem in the quest to
understand high-Tc cuprate superconductors. A fundamental question is what
symmetries are broken when that phase sets in below a temperature T*. There is
evidence from both polarized neutron diffraction and polar Kerr effect
measurements that time- reversal symmetry is broken, but at temperatures that
differ significantly. Broken rotational symmetry was detected by both
resistivity and inelastic neutron scattering at low doping and by scanning
tunnelling spectroscopy at low temperature, but with no clear connection to T*.
Here we report the observation of a large in-plane anisotropy of the Nernst
effect in YBa2Cu3Oy that sets in precisely at T*, throughout the doping phase
diagram. We show that the CuO chains of the orthorhombic lattice are not
responsible for this anisotropy, which is therefore an intrinsic property of
the CuO2 planes. We conclude that the pseudogap phase is an electronic state
which strongly breaks four-fold rotational symmetry. This narrows the range of
possible states considerably, pointing to stripe or nematic orders.Comment: Published version. Journal reference and DOI adde
Observations and Theoretical Implications of the Large Separation Lensed Quasar SDSS J1004+4112
We study the recently discovered gravitational lens SDSS J1004+4112, the
first quasar lensed by a cluster of galaxies. It consists of four images with a
maximum separation of 14.62''. The system has been confirmed as a lensed quasar
at z=1.734 on the basis of deep imaging and spectroscopic follow-up
observations. We present color-magnitude relations for galaxies near the lens
plus spectroscopy of three central cluster members, which unambiguously confirm
that a cluster at z=0.68 is responsible for the large image separation. We find
a wide range of lens models consistent with the data, but they suggest four
general conclusions: (1) the brightest cluster galaxy and the center of the
cluster potential well appear to be offset by several kpc; (2) the cluster mass
distribution must be elongated in the North--South direction, which is
consistent with the observed distribution of cluster galaxies; (3) the
inference of a large tidal shear (~0.2) suggests significant substructure in
the cluster; and (4) enormous uncertainty in the predicted time delays between
the images means that measuring the delays would greatly improve constraints on
the models. We also compute the probability of such large separation lensing in
the SDSS quasar sample, on the basis of the CDM model. The lack of large
separation lenses in previous surveys and the discovery of one in SDSS together
imply a mass fluctuation normalization \sigma_8=1.0^{+0.4}_{-0.2} (95% CL), if
cluster dark matter halos have an inner slope -1.5. Shallower profiles would
require higher values of \sigma_8. Although the statistical conclusion might be
somewhat dependent on the degree of the complexity of the lens potential, the
discovery is consistent with the predictions of the abundance of cluster-scale
halos in the CDM scenario. (Abridged)Comment: 21 pages, 24 figures, 5 tables, accepted for publication in Ap
The Fifth Data Release of the Sloan Digital Sky Survey
This paper describes the Fifth Data Release (DR5) of the Sloan Digital Sky
Survey (SDSS). DR5 includes all survey quality data taken through June 2005 and
represents the completion of the SDSS-I project (whose successor, SDSS-II will
continue through mid-2008). It includes five-band photometric data for 217
million objects selected over 8000 square degrees, and 1,048,960 spectra of
galaxies, quasars, and stars selected from 5713 square degrees of that imaging
data. These numbers represent a roughly 20% increment over those of the Fourth
Data Release; all the data from previous data releases are included in the
present release. In addition to "standard" SDSS observations, DR5 includes
repeat scans of the southern equatorial stripe, imaging scans across M31 and
the core of the Perseus cluster of galaxies, and the first spectroscopic data
from SEGUE, a survey to explore the kinematics and chemical evolution of the
Galaxy. The catalog database incorporates several new features, including
photometric redshifts of galaxies, tables of matched objects in overlap regions
of the imaging survey, and tools that allow precise computations of survey
geometry for statistical investigations.Comment: ApJ Supp, in press, October 2007. This paper describes DR5. The SDSS
Sixth Data Release (DR6) is now public, available from http://www.sdss.or
The Sloan Digital Sky Survey Quasar Lens Search. III. Constraints on Dark Energy from the Third Data Release Quasar Lens Catalog
We present cosmological results from the statistics of lensed quasars in the
Sloan Digital Sky Survey (SDSS) Quasar Lens Search. By taking proper account of
the selection function, we compute the expected number of quasars lensed by
early-type galaxies and their image separation distribution assuming a flat
universe, which is then compared with 7 lenses found in the SDSS Data Release 3
to derive constraints on dark energy under strictly controlled criteria. For a
cosmological constant model (w=-1) we obtain
\Omega_\Lambda=0.74^{+0.11}_{-0.15}(stat.)^{+0.13}_{-0.06}(syst.). Allowing w
to be a free parameter we find
\Omega_M=0.26^{+0.07}_{-0.06}(stat.)^{+0.03}_{-0.05}(syst.) and
w=-1.1\pm0.6(stat.)^{+0.3}_{-0.5}(syst.) when combined with the constraint from
the measurement of baryon acoustic oscillations in the SDSS luminous red galaxy
sample. Our results are in good agreement with earlier lensing constraints
obtained using radio lenses, and provide additional confirmation of the
presence of dark energy consistent with a cosmological constant, derived
independently of type Ia supernovae.Comment: 9 pages, 3 figures, 2 tables, accepted for publication in A
The Seventh Data Release of the Sloan Digital Sky Survey
This paper describes the Seventh Data Release of the Sloan Digital Sky Survey
(SDSS), marking the completion of the original goals of the SDSS and the end of
the phase known as SDSS-II. It includes 11663 deg^2 of imaging data, with most
of the roughly 2000 deg^2 increment over the previous data release lying in
regions of low Galactic latitude. The catalog contains five-band photometry for
357 million distinct objects. The survey also includes repeat photometry over
250 deg^2 along the Celestial Equator in the Southern Galactic Cap. A
coaddition of these data goes roughly two magnitudes fainter than the main
survey. The spectroscopy is now complete over a contiguous area of 7500 deg^2
in the Northern Galactic Cap, closing the gap that was present in previous data
releases. There are over 1.6 million spectra in total, including 930,000
galaxies, 120,000 quasars, and 460,000 stars. The data release includes
improved stellar photometry at low Galactic latitude. The astrometry has all
been recalibrated with the second version of the USNO CCD Astrograph Catalog
(UCAC-2), reducing the rms statistical errors at the bright end to 45
milli-arcseconds per coordinate. A systematic error in bright galaxy photometr
is less severe than previously reported for the majority of galaxies. Finally,
we describe a series of improvements to the spectroscopic reductions, including
better flat-fielding and improved wavelength calibration at the blue end,
better processing of objects with extremely strong narrow emission lines, and
an improved determination of stellar metallicities. (Abridged)Comment: 20 pages, 10 embedded figures. Accepted to ApJS after minor
correction
Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123
P-glycoprotein (P-gp) expression at the blood-brain barrier prevents unwanted blood-borne toxins and signalling molecules from entering the brain. Primary and immortalised human brain endothelial cells (BECs) represent two suitable options for studying P-gp function in vitro. The limited supply of primary human BECs and their instability over passage number makes this choice unattractive for medium/high throughput studies. The aim of this study was to further characterise the expression of P-gp by an immortalised human BEC line, hCMEC/D3, in order to evaluate their use as an in vitro human blood-brain barrier model. P-gp expression was stable over a high passage number (up to passage 38) and was polarised on the apical plasma membrane, consistent with human BECs in vivo. In addition, hCMEC/D3 cell P-gp expression was comparable, albeit slightly lower to that observed in primary isolated human BECs although P-gp function was similar in both cell lines. The P-gp inhibitors tariquidar and vinblastine prevented the efflux of rhodamine 123 (rh123) from hCMEC/D3 cells, indicative of functional P-gp expression. hCMEC/D3 cells also displayed polarised P-gp transport, since both tariquidar and vinblasine selectively increased the apical-to-basolateral permeability of hCMEC/D3 cells to rh123. The results presented here demonstrate that hCMEC/D3 cells are a suitable model to investigate substrate specificity of P-gp in BECs of human origin
hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia
hMTH1 is an 8-oxodGTPase that prevents mis-incorporation of free oxidized nucleotides into genomic DNA. Base excision and mismatch repair pathways also restrict the accumulation of oxidized lesions in DNA by removing the mis-inserted 8-oxo-7,8-dihydro-2'-deoxyguanosines (8-oxodGs). In this study, we aimed to investigate the interplay between hMYH DNA glycosylase and hMTH1 for cancer cell survival by using mismatch repair defective T-cell acute lymphoblastic leukemia (T-ALL) cells. To this end, MYH and MTH1 were silenced individually or simultaneously using small hairpin RNAs. Increased sub-G1 population and apoptotic cells were observed upon concurrent depletion of both enzymes. Elevated cell death was consistent with cleaved caspase 3 accumulation in double knockdown cells. Importantly, overexpression of the nuclear isoform of hMYH could remove the G1 arrest and partially rescue the toxicity observed in hMTH1-depleted cells. In addition, expression profiles of human DNA glycosylases were generated using quantitative reverse transcriptase–PCR in MTH1 and/or MYH knockdown cells. NEIL1 DNA glycosylase, involved in repair of oxidized nucleosides, was found to be significantly downregulated as a cellular response to MTH1–MYH co-suppression. Overall, the results suggest that hMYH and hMTH1 functionally cooperate for effective repair and survival in mismatch repair defective T-ALL Jurkat A3 cells
Superhumps in Cataclysmic Binaries. XXIV. Twenty More Dwarf Novae
We report precise measures of the orbital and superhump period in twenty more
dwarf novae. For ten stars, we report new and confirmed spectroscopic periods -
signifying the orbital period P_o - as well as the superhump period P_sh. These
are GX Cas, HO Del, HS Vir, BC UMa, RZ Leo, KV Dra, KS UMa, TU Crt, QW Ser, and
RZ Sge. For the remaining ten, we report a medley of P_o and P_sh measurements
from photometry; most are new, with some confirmations of previous values.
These are KV And, LL And, WX Cet, MM Hya, AO Oct, V2051 Oph, NY Ser, KK Tel, HV
Vir, and RX J1155.4-5641.
Periods, as usual, can be measured to high accuracy, and these are of special
interest since they carry dynamical information about the binary. We still have
not quite learned how to read the music, but a few things are clear. The
fractional superhump excess epsilon [=(P_sh-P_o)/P_o] varies smoothly with P_o.
The scatter of the points about that smooth curve is quite low, and can be used
to limit the intrinsic scatter in M_1, the white dwarf mass, and the
mass-radius relation of the secondary. The dispersion in M_1 does not exceed
24%, and the secondary-star radii scatter by no more than 11% from a fixed
mass-radius relation. For the well-behaved part of epsilon(P_o) space, we
estimate from superhump theory that the secondaries are 18+-6% larger than
theoretical ZAMS stars. This affects some other testable predictions about the
secondaries: at a fixed P_o, it suggests that the secondaries are (compared
with ZAMS predictions) 40+-14% less massive, 12+-4% smaller, 19+-6% cooler, and
less luminous by a factor 2.5(7). The presence of a well-defined mass-radius
relation, reflected in a well-defined epsilon(P_o) relation, strongly limits
effects of nuclear evolution in the secondaries.Comment: PDF, 62 pages, 7 tables, 21 figures; accepted, in press, to appear
November 2003, PASP; more info at http://cba.phys.columbia.edu
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