55 research outputs found
Extracting the Distribution Amplitudes of the rho meson from the Color Glass Condensate
We extract the leading twist-2 and subleading twist-3 Distribution Amplitudes
(DAs) of the rho meson using the HERA data on diffractive rho photoproduction.
We do so using several Colour Glass Condensate (CGC) inspired and a Regge
inspired dipole models. We find that our extracted twist-2 DA is not much model
dependent and is consistent with QCD Sum Rules and lattice predictions. The
extracted twist-3 DA is more model dependent but is still consistent with the
Sum Rules prediction.Comment: 21 pages, 10 figures, 3 tables. Section 6 revised, figures 8 and 9
and table 3 updated. Conclusions essentially unchange
Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial
Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials.
Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure.
Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen.
Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049
Constraining the magnitude of the chiral magnetic effect with event shape engineering in Pb-Pb collisions at root s(NN)=2.76 TeV
CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTĂFICO E TECNOLĂGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAĂĂO DE AMPARO Ă PESQUISA DO ESTADO DE SĂO PAULOIn ultrarelativistic heavy-ion collisions, the event-by-event variation of the elliptic flow v(2) reflects fluctuations in the shape of the initial state of the system. This allows to select events with the same centrality but different initial geometry. This selection technique, Event Shape Engineering, has been used in the analysis of charge-dependent two-and three-particle correlations in Pb-Pb collisions at root s(NN) = 2.76 TeV. The two-particle correlator < cos(phi(alpha) - phi(ss))gt;, calculated for different combinations of charges alpha and beta, is almost independent of v(2) (for a given centrality), while the three-particle correlator < cos(phi(alpha) + phi(beta) - 2 Psi(2))gt; scales almost linearly both with the event v(2) and charged-particle pseudorapidity density. The charge dependence of the three-particle correlator is often interpreted as evidence for the Chiral Magnetic Effect (CME), a parity violating effect of the strong interaction. However, its measured dependence on v(2) points to a large non-CME contribution to the correlator. Comparing the results with Monte Carlo calculations including a magnetic field due to the spectators, the upper limit of the CME signal contribution to the three-particle correlator in the 10-50% centrality interval is found to be 26-33% at 95% confidence level.777151162CNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTĂFICO E TECNOLĂGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAĂĂO DE AMPARO Ă PESQUISA DO ESTADO DE SĂO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTĂFICO E TECNOLĂGICOFINEP - FINANCIADORA DE ESTUDOS E PROJETOSFAPESP - FUNDAĂĂO DE AMPARO Ă PESQUISA DO ESTADO DE SĂO PAULOSem informaçãoSem informaçãoSem informaçãoAgĂȘncias de fomento estrangeiras apoiaram essa pesquisa, mais informaçÔes acesse artig
Electron capture Beta decay of <SUP>7</SUP>Be located inside and outside the C<SUB>36</SUB> fullerene
NatuurwetenskappeInstituut Vir Teoretiese FisikaPlease help us populate SUNScholar with the post print version of this article. It can be e-mailed to: [email protected]
Improving the Lipophilic Antioxidant Activity of Poultry Protein Hydrolisates Through Chemical Esterification
Purpose: Poultry protein hydrolysates (PPHs) are obtained as by-product of poultry slaughter industry using bio catalytic hydrolysis. These protein hydrolysates have good antioxidant properties, which make them potential functional ingredient to prevent the oxidation of meat derived products. However, protein hydrolysates have a poor solubility in lipid media. Methods: To increase the solubilisation in the lipid phase, thus improving antioxidant properties on the fatty acids, several esterification reactions were carried out using different alcohols. The reactions were monitored by LCâMS and the shift in antioxidant activity was assessed with hydrophilic and lipophilic ABTS assay. Results: A good increase in the lipophilicity of the esterified PPHs is shown, proportional to the increase of the alcohol chain length. Accordingly, a significant increase of the lipophilic antioxidant activity, especially for longest chain alcohols, was also observed. Conclusions: These results indicated that the chemical esterification of PPHs with food-grade long chain alcohol can be a valuable approach to increase the lipophilic antioxidant properties of these products. Graphical Abstract: [Figure not available: see fulltext.]
Hydrogen Storage in Aromatic Carbon Ring based Molecular Materials Decorated with Alkali or Alkali-Earth Metals
NatuurwetenskappeInstituut Vir Teoretiese FisikaPlease help us populate SUNScholar with the post print version of this article. It can be e-mailed to: [email protected]
Estimate of the Ratio of the Data and Background Signals in Detecting the Magnetic Fields of Surface Defects by Magnetic Measurement Transducers
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